ATE89566T1 - Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon. - Google Patents

Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon.

Info

Publication number
ATE89566T1
ATE89566T1 AT88901854T AT88901854T ATE89566T1 AT E89566 T1 ATE89566 T1 AT E89566T1 AT 88901854 T AT88901854 T AT 88901854T AT 88901854 T AT88901854 T AT 88901854T AT E89566 T1 ATE89566 T1 AT E89566T1
Authority
AT
Austria
Prior art keywords
pct
gln
glu
falciparum
hepatocytes
Prior art date
Application number
AT88901854T
Other languages
English (en)
Inventor
Claudine Marchand
Pierre Druilhe
Odile Puijalon-Mercereau
Gordon Langsley
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE89566T1 publication Critical patent/ATE89566T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88901854T 1987-02-09 1988-02-09 Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon. ATE89566T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8701543A FR2610631B1 (fr) 1987-02-09 1987-02-09 Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme
EP88901854A EP0343186B1 (de) 1987-02-09 1988-02-09 Moleküle mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum-produzierten proteins in hepatozyten und zusammensetzungen davon
PCT/FR1988/000074 WO1988005785A1 (fr) 1987-02-09 1988-02-09 Molecules comportant au moins une sequence peptidique porteuse d'un, ou plusieurs, epitopes caracteristiques d'une proteine produite par p. falciparum dans les hepatocytes et compositions les contenant

Publications (1)

Publication Number Publication Date
ATE89566T1 true ATE89566T1 (de) 1993-06-15

Family

ID=9347704

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88901854T ATE89566T1 (de) 1987-02-09 1988-02-09 Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon.

Country Status (8)

Country Link
US (4) US5599542A (de)
EP (1) EP0343186B1 (de)
JP (1) JP2729070B2 (de)
AT (1) ATE89566T1 (de)
AU (1) AU610571B2 (de)
DE (1) DE3881204T2 (de)
FR (1) FR2610631B1 (de)
WO (1) WO1988005785A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2610631B1 (fr) * 1987-02-09 1989-11-24 Pasteur Institut Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme
US6270771B1 (en) * 1988-10-06 2001-08-07 Institut Pasteur Peptide sequences specific for the hepatic stages of P. falciparum bearing epitopes capable of stimulating the T lymphocytes
FR2672290B1 (fr) * 1991-02-05 1995-04-21 Pasteur Institut Sequences peptidiques specifiques des stades hepatiques de p. falciparum porteuses d'epitopes capables de stimuler les lymphocytes t.
FR2656626B1 (fr) * 1989-12-29 1994-08-12 Pasteur Institut Fragment peptidique comprenant une sequence issue de la proteine 28 kda de schistosoma mansoni et compositions vaccinantes et/ou therapeutiques comprenant ledit fragment.
FR2665365B1 (fr) * 1990-08-06 1995-04-28 Pasteur Institut Antigene de plasmodium falciparum susceptible d'induire des anticorps protecteurs - application a la vaccination.
GB9020438D0 (en) * 1990-09-19 1990-10-31 Imperial College Plasmodium liver stage antigens
US20030161840A1 (en) * 1992-10-19 2003-08-28 Institut Pasteur Plasmodium falciparum antigens inducing protective antibodies
FR2697022B1 (fr) 1992-10-19 1994-12-16 Pasteur Institut Antigènes de Plasmodium falciparum capables d'induire des anticorps protecteurs à large spectre - Application à la vaccination.
GB0022017D0 (en) * 2000-09-08 2000-10-25 Univ Dundee Cell assays
EP1201250A1 (de) * 2000-10-25 2002-05-02 SMITHKLINE BEECHAM BIOLOGICALS s.a. Immunogenische Zusammensetzung die hepatische Phaseantigene aus Plasmodium enthält
EP2933334B1 (de) * 2003-02-18 2019-09-18 Baylor College of Medicine Induzierte Aktivierung in dendritischen Zellen
EP2465510B1 (de) 2006-10-19 2018-11-28 Baylor College Of Medicine Verfahren und Zusammensetzungen zur Erzeugung einer Immunreaktion mittels CD40-Induktion sowie Strukturerkennungsrezeptoren und Adapter davon
US20100203067A1 (en) 2008-09-22 2010-08-12 Baylor College Of Medicine Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
WO2011146862A1 (en) 2010-05-21 2011-11-24 Bellicum Pharmaceuticals, Inc. Methods for inducing selective apoptosis
US9434935B2 (en) 2013-03-10 2016-09-06 Bellicum Pharmaceuticals, Inc. Modified caspase polypeptides and uses thereof
US9944690B2 (en) 2013-03-14 2018-04-17 Bellicum Pharmaceuticals, Inc. Methods for controlling T cell proliferation
EP3004329B1 (de) 2013-06-05 2020-03-04 Bellicum Pharmaceuticals, Inc. Verfahren zur induktion von partieller apoptose mit caspasepolypeptiden
CA2937750A1 (en) 2014-02-14 2015-08-20 Bellicum Pharmaceuticals, Inc. Methods for activating t cells using an inducible chimeric polypeptide
EP3189148A4 (de) 2014-09-02 2018-05-02 Bellicum Pharmaceuticals, Inc. Co-stimulierung von chimären antigenrezeptoren durch myd88- und cd40-polypeptide
ES2904301T3 (es) 2014-11-03 2022-04-04 Academisch Ziekenhuis Leiden H O D N Leids Univ Medisch Centrum Receptores de células T dirigidos contra Bob1 y usos de los mismos
EP4219544A1 (de) 2015-03-10 2023-08-02 Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum T-zell-rezeptoren gegen das bevorzugt exprimierte antigen von melanom und deren verwendungen
US20210147507A1 (en) 2017-05-09 2021-05-20 Bellicum Pharmaceuticals, Inc. Methods to augment or alter signal transduction
AU2018378955A1 (en) 2017-12-08 2020-06-18 Bellicum Pharmaceuticals, Inc. Methods for enhancing and maintaining CAR-T cell efficacy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569722B2 (en) * 1983-01-28 1988-02-18 Saramane Pty Ltd Expression of plasmodium falciparum polypeptides from cloned cdna
EP0153188B1 (de) * 1984-02-21 1991-10-09 National Research Development Corporation Herstellung von Malaria-Impfstoffen
US4707357A (en) * 1984-06-26 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
FR2610631B1 (fr) * 1987-02-09 1989-11-24 Pasteur Institut Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme
AU4661889A (en) * 1988-11-30 1990-06-26 Biomedical Research Institute A novel malarial sporozoite and exoerythrocytic peptide antigen
US5139792A (en) * 1990-07-19 1992-08-18 Bio-Techniques Laboratories, Inc. Method and system for dispensing live bacteria into animal feed and drinking water

Also Published As

Publication number Publication date
AU610571B2 (en) 1991-05-23
AU1342888A (en) 1988-08-24
JP2729070B2 (ja) 1998-03-18
WO1988005785A1 (fr) 1988-08-11
EP0343186B1 (de) 1993-05-19
DE3881204T2 (de) 1993-11-11
FR2610631B1 (fr) 1989-11-24
JPH01502194A (ja) 1989-08-03
FR2610631A1 (fr) 1988-08-12
EP0343186A1 (de) 1989-11-29
US5589343A (en) 1996-12-31
US5928901A (en) 1999-07-27
US5602031A (en) 1997-02-11
US5599542A (en) 1997-02-04
DE3881204D1 (de) 1993-06-24

Similar Documents

Publication Publication Date Title
ATE89566T1 (de) Molekuele mit mindestens einer peptidsequenz einer oder mehrerer epitopen eines p.falciparum- produzierten proteins in hepatozyten und zusammensetzungen davon.
NO875476L (no) Elektrokjemiluminiscente analyser.
DK0590071T3 (da) Hovedsagelig rene receptor-lignende TGF-BETA-1 bindende molekyler samt anvendelse deraf
FI946066A0 (fi) Hepatiitti-C viruksen genotyyppien uudet sekvenssit ja niiden käyttö terapeuttisina ja diagnostisina aineina
LU91015I2 (fr) Recombinate (Rurioctocog alfa) dans toutes ses formes couvertes par le brevet de base
GB9710809D0 (en) Nucleic acid binding proteins
DE69029092D1 (de) Synthetische Antigene zum Nachweis von Antikörpern gegen Hepatitis C-Virus
ES2144399T3 (es) Clonado del adn de virus de anemia de los pollos.
ATE70280T1 (de) Charakteristische polypeptide und antikoerper vom papillomavirus, diagnostische verfahren und dieselben verwendende impfungen.
ATE94757T1 (de) Lysolecithinderivate zur behandlung von autoimmunerkrankungen.
PT785950E (pt) Analogos do factor de crescimento de queratinocitos
DK0486572T3 (da) Forbedringer i granulocyt-makrofag-kolonistimulerende faktorreceptor og derivater deraf
DE69226775D1 (de) Dns-sequenzen von hpv42 papillomavirus :verwendungsmöglichkeit für diagnose
ATE230418T1 (de) Monoklonaler antikörper gegen das humane mx- protein mxa
ATE180489T1 (de) Für leberzellkarzinom spezifisches onkogen
DE59508137D1 (de) Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
ATE48142T1 (de) Blutprotein, verfahren zu seiner herstellung, antikoerper gegen dieses protein und dieses protein oder diese antikoerper enthaltende pharmazeutische zubereitungen.
AU5315790A (en) Molecules containing at least one peptide sequence carrying one or several epitopes characteristic of a protein produced by p. falciparum at the sporozoite stage and in the hepatocytes
KR930701605A (ko) 엠. 튜버쿨로시스(M. tuberculosis)의 단백질 MTP 40의 뉴클레오타이드 및 아미노산 서열 및 이로부터 유도된 합성 펩타이드
PT86944A (pt) Verfahren zur isolierung von basalmembranproteinen aus menschlichen und tierischen geweben
DK292584D0 (da) Biologisk aktive konjugater, deres fremstilling og anvendelse
BRPI0409948A (pt) composições de spex e processos de uso
MX9206732A (es) Nuevas proteinas inhibidoras de trombina a partir de sanguijuelas de tierra.
KR950018049A (ko) 사람 dna 토포이소머라제 제i형의 돌연변이체 단백질
ATE27822T1 (de) Hexapeptid, verfahren zur herstellung und pharmazeutische zusammensetzungen hieraus.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time