ATE92318T1 - Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel. - Google Patents

Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel.

Info

Publication number: ATE92318T1
Authority: AT; Austria
Prior art keywords: antidabetic; castanospermine; remedy; isolation; tetrc
Prior art date: 1985-05-24

Application number

AT86106863T

Other languages

English (en)

Inventor

Paul S Liu

Barry L Rhinehart

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-24

Filing date

1986-05-21

Publication date

1993-08-15

1986-05-21 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1993-08-15 Application granted granted Critical

1993-08-15 Publication of ATE92318T1 publication Critical patent/ATE92318T1/de

Links

JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 title 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 title 1
238000002955 isolation Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT86106863T 1985-05-24 1986-05-21 Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel. ATE92318T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73812785A	1985-05-24	1985-05-24
EP86106863A EP0202661B1 (de)	1985-05-24	1986-05-21	Isolierung von Castanospermin und dessen Verwendung als antidiabetisches Heilmittel

Publications (1)

Publication Number	Publication Date
ATE92318T1 true ATE92318T1 (de)	1993-08-15

Family

ID=24966697

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT86106863T ATE92318T1 (de)	1985-05-24	1986-05-21	Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel.
AT92115805T ATE116321T1 (de)	1985-05-24	1986-05-21	Neues verfahren zur isolierung von castanospermin.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT92115805T ATE116321T1 (de)	1985-05-24	1986-05-21	Neues verfahren zur isolierung von castanospermin.

Country Status (5)

Country	Link
EP (2)	EP0202661B1 (de)
JP (2)	JPH0729923B2 (de)
AT (2)	ATE92318T1 (de)
CA (1)	CA1327970C (de)
DE (2)	DE3650190T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3650377T2 (de) *	1985-12-23	1996-02-22	Hutchinson Fred Cancer Res	Regulierung der retroviralen replikation, infektion und pathogenese.
GB8827701D0 (en) *	1987-12-09	1988-12-29	Nippon Shinyaku Co Ltd	Thrombolytic &c compositions
US5192772A (en) *	1987-12-09	1993-03-09	Nippon Shinyaku Co. Ltd.	Therapeutic agents
JPH04500959A (ja) *	1988-08-10	1992-02-20	ジオーストラリアンナショナルユニバーシティー	抗炎症剤および免疫抑制剤としてのカスタノスペルミンの使用
AU618838B2 (en) *	1988-08-10	1992-01-09	Praxis Pharmaceuticals, Inc.	Use of castanospermine as an anti-inflammatory and immunosuppressant agent
GB8924292D0 (en) *	1989-10-27	1989-12-13	Novalal Ltd	The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5844102A (en) *	1994-07-07	1998-12-01	University Of Maryland Baltimore County	Glycohydrolase inhibitors, their preparation and use thereof
BR112018072298A2 (pt)	2016-05-02	2019-02-12	Florida State University Research Foundation, Inc.	tratamento de infecções pelo vírus da zika usando inibidores da alfa-glicosidase
US11518762B2 (en) *	2020-06-04	2022-12-06	Florida State University Research Foundation, Inc.	Large scale purification of castanospermine

1986
- 1986-05-20 CA CA000509494A patent/CA1327970C/en not_active Expired - Fee Related
- 1986-05-21 JP JP61114990A patent/JPH0729923B2/ja not_active Expired - Lifetime
- 1986-05-21 DE DE3650190T patent/DE3650190T2/de not_active Expired - Fee Related
- 1986-05-21 AT AT86106863T patent/ATE92318T1/de not_active IP Right Cessation
- 1986-05-21 DE DE86106863T patent/DE3688807T2/de not_active Expired - Fee Related
- 1986-05-21 EP EP86106863A patent/EP0202661B1/de not_active Expired - Lifetime
- 1986-05-21 AT AT92115805T patent/ATE116321T1/de not_active IP Right Cessation
- 1986-05-21 EP EP92115805A patent/EP0522599B1/de not_active Expired - Lifetime
1994
- 1994-09-29 JP JP6259063A patent/JP2528083B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ATE116321T1 (de)	1995-01-15
DE3650190D1 (de)	1995-02-09
CA1327970C (en)	1994-03-22
DE3688807D1 (de)	1993-09-09
EP0202661A3 (en)	1990-07-25
DE3688807T2 (de)	1994-02-10
JPS61271220A (ja)	1986-12-01
JPH07252151A (ja)	1995-10-03
EP0522599A1 (de)	1993-01-13
JPH0729923B2 (ja)	1995-04-05
JP2528083B2 (ja)	1996-08-28
EP0202661A2 (de)	1986-11-26
DE3650190T2 (de)	1995-05-11
EP0522599B1 (de)	1994-12-28
EP0202661B1 (de)	1993-08-04

Similar Documents

Publication	Publication Date	Title
AU566960B2 (en)	1987-11-05	7-aminoazolo (1,5-alpha) pyrimidines
AU584388B2 (en)	1989-05-25	Novel heterocyclic compounds
GR880100248A (el)	1989-01-31	Ουσιες για την προφυλαξη και θεραπεια ρετροιογενην φλεγμωνων.
AU568513B2 (en)	1988-01-07	Beta-carbolines
ATE53837T1 (de)	1990-06-15	Pyridin-derivate, ihre herstellung und verwendung.
ATE92318T1 (de)	1993-08-15	Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel.
FI853624A0 (fi)	1985-09-20	1-substituerade tetralinderivat, deras framstaellning och anvaendning.
ATE88343T1 (de)	1993-05-15	Anxiolytisches praeparat.
IT1208604B (it)	1989-07-10	Blocchetto di nastri medicali.
ATE84043T1 (de)	1993-01-15	Aminosaeurederivate.
DE3881270D1 (de)	1993-07-01	Verwendung von pyrrolidon-derivaten als antiamnetikum.
GR1000887B (el)	1993-03-16	Νεα παραγωγα σπιροφουρανης.
FI842112A0 (fi)	1984-05-25	Foerfarande foer framstaellning av- karbolin-3-karboxylsyraderivat.
FI860074A0 (fi)	1986-01-08	Oktahydroindolizinfoereningar anvaendbara som smaertstillande medel.
NO863616D0 (no)	1986-09-10	Fremgangsmaate for fremstilling av n-sulfamyl-3-(2-guanidino-thiazolo-4-yl-methylthio)-propionamid.
ATE47392T1 (de)	1989-11-15	4-substituierte 10-cyanmethylen-thieno(4,3-e>benzo-azepine.
SE8504409D0 (sv)	1985-09-24	Novel chemical intermediates
DE3676116D1 (de)	1991-01-24	Herstellung von azetidin-derivaten.
DE3777432D1 (de)	1992-04-23	Verwendung von 2-aminoalkyl-5-pyridinol-verbindungen als nootropika und antidepressiva.
SU1269465A1 (ru)	1996-04-10	Способ получения 2-анилино-7-гидрокси-6н-1,3,4-тиадиазепинов
SU1626642A1 (ru)	2006-12-20	3-Алкил-4-метил-2,9-диоксо-3,8-диазабицикло[4,3,0]нона-1(6), 4-диенилийперхлораты, обладающие противовоспалительным действием
SU1266156A1 (ru)	2016-08-27	7-морфолинокумарины в качестве красителей для лазерной техники
SE8600650D0 (sv)	1986-02-14	Gangjern
SU1732643A1 (ru)	2001-06-10	Амиды n-этоксиоксалилантраниловой кислоты, проявляющие противовоспалительную и анальгетическую активность
SE8503608D0 (sv)	1985-07-26	Reglerkrets, foretredesvis avsedd for angbadrum

Legal Events

Date	Code	Title	Description
1994-05-15	UEP	Publication of translation of european patent specification
2001-02-15	REN	Ceased due to non-payment of the annual fee