ATE116321T1 - Neues verfahren zur isolierung von castanospermin. - Google Patents
Neues verfahren zur isolierung von castanospermin.Info
- Publication number
- ATE116321T1 ATE116321T1 AT92115805T AT92115805T ATE116321T1 AT E116321 T1 ATE116321 T1 AT E116321T1 AT 92115805 T AT92115805 T AT 92115805T AT 92115805 T AT92115805 T AT 92115805T AT E116321 T1 ATE116321 T1 AT E116321T1
- Authority
- AT
- Austria
- Prior art keywords
- castanospermine
- isolation
- new method
- tetrc
- enydroxyindolizidine
- Prior art date
Links
- JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 title 1
- JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 title 1
- 238000002955 isolation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73812785A | 1985-05-24 | 1985-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE116321T1 true ATE116321T1 (de) | 1995-01-15 |
Family
ID=24966697
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86106863T ATE92318T1 (de) | 1985-05-24 | 1986-05-21 | Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel. |
| AT92115805T ATE116321T1 (de) | 1985-05-24 | 1986-05-21 | Neues verfahren zur isolierung von castanospermin. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86106863T ATE92318T1 (de) | 1985-05-24 | 1986-05-21 | Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel. |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP0202661B1 (de) |
| JP (2) | JPH0729923B2 (de) |
| AT (2) | ATE92318T1 (de) |
| CA (1) | CA1327970C (de) |
| DE (2) | DE3688807T2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987003903A1 (en) * | 1985-12-23 | 1987-07-02 | Fred Hutchinson Cancer Research Center | Regulating retroviral replication, infection, and pathogenesis |
| GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
| US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
| JPH04500959A (ja) * | 1988-08-10 | 1992-02-20 | ジ オーストラリアン ナショナル ユニバーシティー | 抗炎症剤および免疫抑制剤としてのカスタノスペルミンの使用 |
| AU618838B2 (en) * | 1988-08-10 | 1992-01-09 | Praxis Pharmaceuticals, Inc. | Use of castanospermine as an anti-inflammatory and immunosuppressant agent |
| GB8924292D0 (en) * | 1989-10-27 | 1989-12-13 | Novalal Ltd | The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase |
| US5844102A (en) * | 1994-07-07 | 1998-12-01 | University Of Maryland Baltimore County | Glycohydrolase inhibitors, their preparation and use thereof |
| US10328061B2 (en) | 2016-05-02 | 2019-06-25 | Florida State University Research Foundation, Inc. | Treatment of Zika virus infections using alpha-glucosidase inhibitors |
| WO2021248164A1 (en) * | 2020-06-04 | 2021-12-09 | Florida State University Research Foundation, Inc. | Large scale purification of castanospermine |
-
1986
- 1986-05-20 CA CA000509494A patent/CA1327970C/en not_active Expired - Fee Related
- 1986-05-21 JP JP61114990A patent/JPH0729923B2/ja not_active Expired - Lifetime
- 1986-05-21 AT AT86106863T patent/ATE92318T1/de not_active IP Right Cessation
- 1986-05-21 EP EP86106863A patent/EP0202661B1/de not_active Expired - Lifetime
- 1986-05-21 EP EP92115805A patent/EP0522599B1/de not_active Expired - Lifetime
- 1986-05-21 DE DE86106863T patent/DE3688807T2/de not_active Expired - Fee Related
- 1986-05-21 AT AT92115805T patent/ATE116321T1/de not_active IP Right Cessation
- 1986-05-21 DE DE3650190T patent/DE3650190T2/de not_active Expired - Fee Related
-
1994
- 1994-09-29 JP JP6259063A patent/JP2528083B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0522599B1 (de) | 1994-12-28 |
| EP0202661A3 (en) | 1990-07-25 |
| DE3688807T2 (de) | 1994-02-10 |
| DE3650190T2 (de) | 1995-05-11 |
| ATE92318T1 (de) | 1993-08-15 |
| JPH0729923B2 (ja) | 1995-04-05 |
| EP0202661B1 (de) | 1993-08-04 |
| DE3688807D1 (de) | 1993-09-09 |
| JP2528083B2 (ja) | 1996-08-28 |
| DE3650190D1 (de) | 1995-02-09 |
| CA1327970C (en) | 1994-03-22 |
| EP0202661A2 (de) | 1986-11-26 |
| JPH07252151A (ja) | 1995-10-03 |
| EP0522599A1 (de) | 1993-01-13 |
| JPS61271220A (ja) | 1986-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |