ATE116321T1 - Neues verfahren zur isolierung von castanospermin. - Google Patents

Neues verfahren zur isolierung von castanospermin.

Info

Publication number: ATE116321T1
Authority: AT; Austria
Prior art keywords: castanospermine; isolation; new method; tetrc; enydroxyindolizidine
Prior art date: 1985-05-24

Application number

AT92115805T

Other languages

English (en)

Inventor

Paul S Liu

Barry L Rhinehart

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-24

Filing date

1986-05-21

Publication date

1995-01-15

1986-05-21 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1995-01-15 Application granted granted Critical

1995-01-15 Publication of ATE116321T1 publication Critical patent/ATE116321T1/de

Links

JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 title 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 title 1
238000002955 isolation Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT92115805T 1985-05-24 1986-05-21 Neues verfahren zur isolierung von castanospermin. ATE116321T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73812785A	1985-05-24	1985-05-24

Publications (1)

Publication Number	Publication Date
ATE116321T1 true ATE116321T1 (de)	1995-01-15

Family

ID=24966697

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT92115805T ATE116321T1 (de)	1985-05-24	1986-05-21	Neues verfahren zur isolierung von castanospermin.
AT86106863T ATE92318T1 (de)	1985-05-24	1986-05-21	Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT86106863T ATE92318T1 (de)	1985-05-24	1986-05-21	Isolierung von castanospermin und dessen verwendung als antidiabetisches heilmittel.

Country Status (5)

Country	Link
EP (2)	EP0522599B1 (de)
JP (2)	JPH0729923B2 (de)
AT (2)	ATE116321T1 (de)
CA (1)	CA1327970C (de)
DE (2)	DE3688807T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE126696T1 (de) *	1985-12-23	1995-09-15	Hutchinson Fred Cancer Res	Regulierung der retroviralen replikation, infektion und pathogenese.
GB8827701D0 (en) *	1987-12-09	1988-12-29	Nippon Shinyaku Co Ltd	Thrombolytic &c compositions
US5192772A (en) *	1987-12-09	1993-03-09	Nippon Shinyaku Co. Ltd.	Therapeutic agents
AU618838B2 (en) *	1988-08-10	1992-01-09	Praxis Pharmaceuticals, Inc.	Use of castanospermine as an anti-inflammatory and immunosuppressant agent
WO1990001319A1 (en) *	1988-08-10	1990-02-22	The Australian National University	Use of castanospermine as an anti-inflammatory and immunosuppressant agent
GB8924292D0 (en) *	1989-10-27	1989-12-13	Novalal Ltd	The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5844102A (en) *	1994-07-07	1998-12-01	University Of Maryland Baltimore County	Glycohydrolase inhibitors, their preparation and use thereof
WO2017192599A1 (en) *	2016-05-02	2017-11-09	Florida State University Research Foundation, Inc.	Treatment of zika virus infections using alpha-glucosidase inhibitors
WO2021248164A1 (en) *	2020-06-04	2021-12-09	Florida State University Research Foundation, Inc.	Large scale purification of castanospermine

1986
- 1986-05-20 CA CA000509494A patent/CA1327970C/en not_active Expired - Fee Related
- 1986-05-21 EP EP92115805A patent/EP0522599B1/de not_active Expired - Lifetime
- 1986-05-21 AT AT92115805T patent/ATE116321T1/de not_active IP Right Cessation
- 1986-05-21 AT AT86106863T patent/ATE92318T1/de not_active IP Right Cessation
- 1986-05-21 DE DE86106863T patent/DE3688807T2/de not_active Expired - Fee Related
- 1986-05-21 JP JP61114990A patent/JPH0729923B2/ja not_active Expired - Lifetime
- 1986-05-21 EP EP86106863A patent/EP0202661B1/de not_active Expired - Lifetime
- 1986-05-21 DE DE3650190T patent/DE3650190T2/de not_active Expired - Fee Related
1994
- 1994-09-29 JP JP6259063A patent/JP2528083B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0522599A1 (de)	1993-01-13
JP2528083B2 (ja)	1996-08-28
JPH07252151A (ja)	1995-10-03
ATE92318T1 (de)	1993-08-15
JPS61271220A (ja)	1986-12-01
EP0202661A2 (de)	1986-11-26
DE3688807D1 (de)	1993-09-09
JPH0729923B2 (ja)	1995-04-05
EP0522599B1 (de)	1994-12-28
DE3650190T2 (de)	1995-05-11
DE3650190D1 (de)	1995-02-09
EP0202661A3 (en)	1990-07-25
EP0202661B1 (de)	1993-08-04
DE3688807T2 (de)	1994-02-10
CA1327970C (en)	1994-03-22

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Legal Events

Date	Code	Title	Description
1995-07-15	UEP	Publication of translation of european patent specification
2001-02-15	REN	Ceased due to non-payment of the annual fee