ATE95422T1 - Ein synthetisches nonapeptid zur verwendung als adjuvant. - Google Patents

Ein synthetisches nonapeptid zur verwendung als adjuvant.

Info

Publication number
ATE95422T1
ATE95422T1 AT88830056T AT88830056T ATE95422T1 AT E95422 T1 ATE95422 T1 AT E95422T1 AT 88830056 T AT88830056 T AT 88830056T AT 88830056 T AT88830056 T AT 88830056T AT E95422 T1 ATE95422 T1 AT E95422T1
Authority
AT
Austria
Prior art keywords
adjuvant
thymo
synthetic nonapeptide
peptide
synthetic
Prior art date
Application number
AT88830056T
Other languages
English (en)
Inventor
Luciano Nencioni
Guido Antoni
Diana Boraschi
Aldo Tagliabue
Original Assignee
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo Spa filed Critical Sclavo Spa
Application granted granted Critical
Publication of ATE95422T1 publication Critical patent/ATE95422T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AT88830056T 1987-02-20 1988-02-16 Ein synthetisches nonapeptid zur verwendung als adjuvant. ATE95422T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19434/87A IT1217314B (it) 1987-02-20 1987-02-20 Nonapeptide sintetico ad attivita'adiuvante capace di potenziare in vivo la risposta anticorporale
EP88830056A EP0293333B1 (de) 1987-02-20 1988-02-16 Ein synthetisches Nonapeptid zur Verwendung als Adjuvant

Publications (1)

Publication Number Publication Date
ATE95422T1 true ATE95422T1 (de) 1993-10-15

Family

ID=11157912

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88830056T ATE95422T1 (de) 1987-02-20 1988-02-16 Ein synthetisches nonapeptid zur verwendung als adjuvant.

Country Status (7)

Country Link
US (1) US5206014A (de)
EP (1) EP0293333B1 (de)
JP (1) JPS63301829A (de)
AT (1) ATE95422T1 (de)
DE (1) DE3884672T2 (de)
ES (1) ES2059562T3 (de)
IT (1) IT1217314B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057010C (en) * 1989-05-25 2002-08-06 Paul B. Chapman Anti-idiotypic antibody which induces an immune response against a glycosphingolipid and use thereof
US6432402B1 (en) 1989-05-25 2002-08-13 Sloan-Kettering Institute For Cancer Research Anti-idiotypic antibody which induces an immune response against a glycosphingolipid and use thereof
IT1262898B (it) * 1992-03-23 1996-07-22 Antigeni ricombinanti proteici ad aumentata immunogenicita' contenenti il peptide rappresentato dalla sequenza vqgeesndk
US6270758B1 (en) 1998-10-08 2001-08-07 Duke University Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
ATE413191T1 (de) * 1999-12-03 2008-11-15 Celltech Chiroscience Ltd Verwendung of interleukin-1 mutein als impfstoffadjuvans

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4283328A (en) * 1979-10-01 1981-08-11 Research Corporation Preparation of dehydropeptides
EP0033384B1 (de) * 1980-01-18 1984-02-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente
JPS57197223A (en) * 1981-05-27 1982-12-03 Eisai Co Ltd Immunoenhancing agent containing ricin b chain
DE3224379A1 (de) * 1982-06-30 1984-01-12 Hoechst Ag, 6230 Frankfurt Nonapeptid mit immunstimulierender wirkung, verfahren zu dessen herstellung und dessen verwendung
DE3230151A1 (de) * 1982-08-13 1984-02-16 Hoechst Ag, 6230 Frankfurt Neues polypeptid mit wirkung auf das immunsystem, verfahren zu seiner isolierung und reinigung, seine verwendung, dieses enthaltende mittel sowie seine spaltprodukte, deren verwendung und diese enthaltende mittel
US4845079A (en) * 1985-01-23 1989-07-04 Luly Jay R Peptidylaminodiols
IT1188550B (it) * 1986-02-07 1988-01-14 Sclavo Spa Peptide sintetico ad attivita' interleukina 1 umana

Also Published As

Publication number Publication date
EP0293333B1 (de) 1993-10-06
US5206014A (en) 1993-04-27
EP0293333A2 (de) 1988-11-30
DE3884672T2 (de) 1994-04-28
ES2059562T3 (es) 1994-11-16
IT1217314B (it) 1990-03-22
JPS63301829A (ja) 1988-12-08
DE3884672D1 (de) 1993-11-11
IT8719434A0 (it) 1987-02-20
EP0293333A3 (en) 1990-09-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties