ES2056858T3 - Esplenopentinas aciladas modificadas, procedimiento para su fabricacion y su uso. - Google Patents

Esplenopentinas aciladas modificadas, procedimiento para su fabricacion y su uso.

Info

Publication number
ES2056858T3
ES2056858T3 ES88109774T ES88109774T ES2056858T3 ES 2056858 T3 ES2056858 T3 ES 2056858T3 ES 88109774 T ES88109774 T ES 88109774T ES 88109774 T ES88109774 T ES 88109774T ES 2056858 T3 ES2056858 T3 ES 2056858T3
Authority
ES
Spain
Prior art keywords
splenopentins
aciled
procedure
manufacture
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88109774T
Other languages
English (en)
Inventor
Klaus Dr Rer Nat Forner
Angelika Ehrlich
Wolfgang Prof Dr Sc Med Diezel
Rolf Dr Rer Nat Eckert
Elke Dr Rer Nat Euthin
Eberhard Dr Rer Nat Krause
Peter Slonina
Hans-Dieter Dr Med Volk
Heinrich Dr Sc Nat Repke
Monika Georgi
Martina Leidert
Michael Dr Sc Nat Bienert
Michail Ovcinnikov
Ralph Schmidt
Manfred Dr Rer Nat Schutt
Renate Dr Rer Nat Mentel
Winfried Dr Med Breustedt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berlin Chemie AG
Original Assignee
Berlin Chemie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DD30397587A external-priority patent/DD263778A1/de
Priority claimed from DD31108087A external-priority patent/DD281089A7/de
Priority claimed from DD31214488A external-priority patent/DD268160A1/de
Application filed by Berlin Chemie AG filed Critical Berlin Chemie AG
Application granted granted Critical
Publication of ES2056858T3 publication Critical patent/ES2056858T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA INVENCION TRATA DE NUEVOS COMPUESTOS SPLENOPENTINOS ACILADOS DE LA FORMULA(I). PROCEDIMIENTO PARA SU OBTENCION POR ACILACION DE SPLENOPENTINOS ASI COMO SU UTILIZACION COMO PEPTIDO FARMACOLOGICAMENTE EFICAZ. LOS COMPUESTOS SON APTOS PARA NORMALIZAR EL FUNCIONAMIENTO DEL SISTEMA INMUNOLOGICO POR INMUNODEFICIENCIAS PRIMARIAS Y SECUNDARIAS.
ES88109774T 1987-06-19 1988-06-20 Esplenopentinas aciladas modificadas, procedimiento para su fabricacion y su uso. Expired - Lifetime ES2056858T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DD30397587A DD263778A1 (de) 1987-06-19 1987-06-19 Verfahren zur herstellung acylierter splenopentine
DD31108087A DD281089A7 (de) 1987-12-23 1987-12-23 Verfahren zur chromatographischen reinigung von acylierten splenopentin-peptiden
DD31214488A DD268160A1 (de) 1988-01-08 1988-01-08 Verfahren zur herstellung eines mittels mit wirkung auf knochenmarkstammzellen

Publications (1)

Publication Number Publication Date
ES2056858T3 true ES2056858T3 (es) 1994-10-16

Family

ID=27179904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88109774T Expired - Lifetime ES2056858T3 (es) 1987-06-19 1988-06-20 Esplenopentinas aciladas modificadas, procedimiento para su fabricacion y su uso.

Country Status (6)

Country Link
EP (1) EP0307553B1 (es)
JP (1) JPS6485998A (es)
AT (1) ATE107311T1 (es)
DE (1) DE3850196D1 (es)
ES (1) ES2056858T3 (es)
HU (1) HU199878B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD296084A5 (de) * 1989-07-27 1991-11-21 Adw Verfahren zur herstellung von humanen spleninderivaten
DD292382B5 (de) * 1990-03-06 1994-03-24 Berlin Chemie Ag Verfahren zur herstellung eines parenteral applizierbaren lagerbestaendigen immunstimulierenden praeparats
DE4011207A1 (de) * 1990-04-06 1991-10-10 Stiefel Thomas Humane splenopentinderivate und verfahren zu deren herstellung
EP0517126A1 (de) * 1991-05-31 1992-12-09 WOGEPHARM GmbH Verwendung von Diacetyl-Splenopentin bei der Chemo- und Strahlentherapie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2938420A1 (de) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt Neue peptide und verfahren zu ihrer herstellung
US4309340A (en) * 1980-03-31 1982-01-05 American Home Products Corporation Polypeptide compositions
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
DE3401545A1 (de) * 1983-08-03 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue peptide mit immunstimulierender wirkung, verfahren zu deren herstellung und deren verwendung
US4629723A (en) * 1984-06-27 1986-12-16 Ortho Pharmaceutical Corporation Potent thymopentin analogs

Also Published As

Publication number Publication date
HUT47310A (en) 1989-02-28
HU199878B (en) 1990-03-28
EP0307553B1 (de) 1994-06-15
EP0307553A3 (en) 1990-05-09
ATE107311T1 (de) 1994-07-15
JPS6485998A (en) 1989-03-30
EP0307553A2 (de) 1989-03-22
DE3850196D1 (de) 1994-07-21

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