ATE96664T1 - Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken. - Google Patents

Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken.

Info

Publication number
ATE96664T1
ATE96664T1 AT89305478T AT89305478T ATE96664T1 AT E96664 T1 ATE96664 T1 AT E96664T1 AT 89305478 T AT89305478 T AT 89305478T AT 89305478 T AT89305478 T AT 89305478T AT E96664 T1 ATE96664 T1 AT E96664T1
Authority
AT
Austria
Prior art keywords
triglycerides
cholesterol
mammals
beta
fatty acid
Prior art date
Application number
AT89305478T
Other languages
English (en)
Inventor
Rolf Kristian Berge
Jon Bremer
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Application granted granted Critical
Publication of ATE96664T1 publication Critical patent/ATE96664T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT89305478T 1988-06-02 1989-05-31 Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken. ATE96664T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888813012A GB8813012D0 (en) 1988-06-02 1988-06-02 Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals
EP89305478A EP0345038B1 (de) 1988-06-02 1989-05-31 Nicht-beta-oxidierbare Fettsäure-Analoge, die die Blutkonzentration von Cholesterin und Triglyceriden bei Säugetieren senken

Publications (1)

Publication Number Publication Date
ATE96664T1 true ATE96664T1 (de) 1993-11-15

Family

ID=10637920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89305478T ATE96664T1 (de) 1988-06-02 1989-05-31 Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken.

Country Status (8)

Country Link
US (1) US5093365A (de)
EP (1) EP0345038B1 (de)
AT (1) ATE96664T1 (de)
CA (1) CA1329550C (de)
DE (1) DE68910386T2 (de)
DK (1) DK267689A (de)
ES (1) ES2059749T3 (de)
GB (1) GB8813012D0 (de)

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JPH10507179A (ja) * 1994-10-13 1998-07-14 ペプチド テクノロジー リミテッド 修飾ポリ不飽和脂肪酸
NO952796D0 (no) * 1995-07-14 1995-07-14 Rolf Berge Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater
WO1999058120A1 (en) * 1998-05-08 1999-11-18 Rolf Berge USE OF NON-β-OXIDIZABLE FATTY ACID ANALOGUES FOR TREATMENT OF SYNDROME-X CONDITIONS
US20020074691A1 (en) * 1999-09-14 2002-06-20 Robert M Mortellite High speed method of making plastic film and nonwoven laminates
AUPQ291499A0 (en) * 1999-09-17 1999-10-07 Women's And Children's Hospital Adelaide Novel nitro and sulphur containing compounds
NO328803B1 (no) 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
PL364178A1 (en) * 2001-01-26 2004-12-13 Schering Corporation Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
AU2002241956A1 (en) * 2001-01-26 2002-08-06 Schering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US20020183305A1 (en) * 2001-01-26 2002-12-05 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
EP1911462A3 (de) 2001-01-26 2011-11-30 Schering Corporation Zusammensetzungen enthaltend einen Sterolabsorptionshemmer
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
IL156585A0 (en) * 2001-01-26 2004-01-04 Schering Corp Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
HU230253B1 (hu) * 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
DK1355644T3 (da) * 2001-01-26 2006-10-23 Schering Corp Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
JP2004532868A (ja) * 2001-05-25 2004-10-28 シェーリング　コーポレイション アルツハイマー病の処置におけるアゼチジノン置換誘導体の使用
FR2828487B1 (fr) * 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
JP2005504091A (ja) * 2001-09-21 2005-02-10 シェーリング　コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
AU2002335770B2 (en) * 2001-09-21 2005-08-18 Merck Sharp & Dohme Corp. Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s)
NZ537762A (en) * 2002-06-20 2007-02-23 Thia Medica As Sulfur-containing phospholipid derivatives
US20040067267A1 (en) * 2002-10-08 2004-04-08 Murthy Pothapragada Suryanarayana Process for preparation of cholesterol lowering compositions from garlic
WO2004043457A1 (en) * 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) * 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング　コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
EP1680189A2 (de) * 2003-11-05 2006-07-19 Schering Corporation Kombinationen von lipidmodulierenden mitteln mit substituierten azetidinonen zur behandlung von vaskularen erkrankungen
US20090215895A1 (en) * 2004-01-30 2009-08-27 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
JP2008506774A (ja) * 2004-07-19 2008-03-06 ティア メディカ アクスイェ セルスカプ タンパク質材料と非酸化性脂肪酸体を含む組成物
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
AU2014229506B2 (en) 2013-03-11 2017-04-13 Nobesita As Natural lipids containing non-oxidizable fatty acids
CA2904898C (en) 2013-03-11 2019-10-15 Jan Remmereit Lipid compositions containing bioactive fatty acids

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Publication number Priority date Publication date Assignee Title
DE2208533A1 (de) * 1972-02-23 1973-09-27 Kolmar Laboratories Neue alkylthioaether
NL7405744A (en) * 1974-04-29 1975-10-31 Dow Chemical Co Butylphenyl-thioalkane carboxylic acids - as hypocholesterolaemics and antilipaemics from corresp. thiophenols and haloalkane carboxylic acids
DE2515146A1 (de) * 1975-04-08 1976-10-21 Bayer Ag Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2856683A1 (de) * 1978-12-29 1980-07-17 Nattermann A & Cie Entzuendungshemmende und antiatherosklerotisch wirkende arzneimittel
CH661207A5 (en) * 1980-06-30 1987-07-15 Hoerrmann Wilhelm Pharmaceutical composition containing long-chain aldehydes or carboxylic acids

Also Published As

Publication number Publication date
DE68910386D1 (de) 1993-12-09
US5093365A (en) 1992-03-03
EP0345038A2 (de) 1989-12-06
EP0345038B1 (de) 1993-11-03
DK267689A (da) 1989-12-03
ES2059749T3 (es) 1994-11-16
GB8813012D0 (en) 1988-07-06
CA1329550C (en) 1994-05-17
EP0345038A3 (de) 1991-06-12
DK267689D0 (da) 1989-06-01
DE68910386T2 (de) 1994-06-09

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