ATE98231T1 - Piperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. - Google Patents

Piperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.

Info

Publication number
ATE98231T1
ATE98231T1 AT90400006T AT90400006T ATE98231T1 AT E98231 T1 ATE98231 T1 AT E98231T1 AT 90400006 T AT90400006 T AT 90400006T AT 90400006 T AT90400006 T AT 90400006T AT E98231 T1 ATE98231 T1 AT E98231T1
Authority
AT
Austria
Prior art keywords
group
fluorobenzoyl
piperidines
piperidyl
nitrogen atom
Prior art date
Application number
AT90400006T
Other languages
English (en)
Inventor
Gerard Ferrand
Herve Dumas
Jean-Claude Depin
Gilles Chavernac
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Application granted granted Critical
Publication of ATE98231T1 publication Critical patent/ATE98231T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT90400006T 1989-01-05 1990-01-03 Piperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. ATE98231T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8900071A FR2641278B1 (fr) 1989-01-05 1989-01-05 Piperidines, procedes de preparation et medicaments les contenant
EP90400006A EP0377528B1 (de) 1989-01-05 1990-01-03 Piperidine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE98231T1 true ATE98231T1 (de) 1993-12-15

Family

ID=9377487

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90400006T ATE98231T1 (de) 1989-01-05 1990-01-03 Piperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.

Country Status (23)

Country Link
US (1) US5001134A (de)
EP (1) EP0377528B1 (de)
JP (1) JP2927480B2 (de)
AT (1) ATE98231T1 (de)
AU (1) AU634739B2 (de)
CA (1) CA2007127A1 (de)
DD (1) DD291323A5 (de)
DE (1) DE69004973T2 (de)
DK (1) DK0377528T3 (de)
ES (1) ES2062425T3 (de)
FR (1) FR2641278B1 (de)
HU (1) HUT58053A (de)
IL (1) IL92950A0 (de)
MA (1) MA21719A1 (de)
MX (1) MX26760A (de)
NO (1) NO900019L (de)
NZ (1) NZ232023A (de)
OA (1) OA09433A (de)
PT (1) PT92782A (de)
RU (1) RU1838299C (de)
TN (1) TNSN90002A1 (de)
YU (1) YU2290A (de)
ZA (1) ZA9061B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
JPH07502268A (ja) * 1991-11-27 1995-03-09 ノボ　ノルディスク　アクティーゼルスカブ 化学化合物、それらの製法および使用
US5378714A (en) * 1991-11-27 1995-01-03 Novo Nordisk A/S Antipsychotic piperidine derivatives
WO1994006765A1 (fr) * 1992-09-17 1994-03-31 Nippon Soda Co., Ltd. Compose heterocyclique azote, son procede de production, et agent de lutte contre les parasites
US5633274A (en) * 1993-02-18 1997-05-27 President And Fellows Of Harvard College Cancer treatments
US5512591A (en) * 1993-02-18 1996-04-30 President And Fellows Of Harvard College Treatments for diseases characterized by neovascularization
DK60593D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
DK60693D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
DK60793D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
DK60893D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Piperidinderivater, deres fremstilling og anvendelse
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
US5556871A (en) * 1995-04-24 1996-09-17 President & Fellows Of Harvard College Method for treating epithelial precancerous lesions with topical inidazoles
US6605623B1 (en) * 1998-12-18 2003-08-12 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2350730A1 (en) * 1998-12-18 2000-06-22 George V. Delucca N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
EP1156807A4 (de) * 1998-12-18 2002-04-03 Du Pont Pharm Co N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
DE69926919D1 (de) 1998-12-18 2005-09-29 Bristol Myers Squibb Pharma Co N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
NZ521576A (en) * 2000-02-29 2005-06-24 Mitsubishi Pharma Corp Novel cyclic amide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355037A (en) * 1981-11-12 1982-10-19 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidyl)-1,2-benzisoxales
FR2527205A1 (fr) * 1982-05-18 1983-11-25 Bouchara Emile Nouvelles phenyloxoalcoyl piperidines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

Also Published As

Publication number Publication date
DD291323A5 (de) 1991-06-27
ES2062425T3 (es) 1994-12-16
HU900039D0 (en) 1990-03-28
AU4771390A (en) 1990-07-12
JPH02225465A (ja) 1990-09-07
FR2641278B1 (fr) 1991-03-22
YU2290A (en) 1992-05-28
OA09433A (fr) 1992-10-15
DE69004973T2 (de) 1994-06-23
MA21719A1 (fr) 1990-10-01
MX26760A (es) 1994-02-28
DE69004973D1 (de) 1994-01-20
AU634739B2 (en) 1993-03-04
CA2007127A1 (fr) 1990-07-05
RU1838299C (ru) 1993-08-30
IL92950A0 (en) 1990-09-17
DK0377528T3 (da) 1994-04-11
NO900019L (no) 1990-07-06
JP2927480B2 (ja) 1999-07-28
EP0377528B1 (de) 1993-12-08
PT92782A (pt) 1990-07-31
EP0377528A1 (de) 1990-07-11
NO900019D0 (no) 1990-01-04
US5001134A (en) 1991-03-19
HUT58053A (en) 1992-01-28
ZA9061B (en) 1990-10-31
FR2641278A1 (fr) 1990-07-06
TNSN90002A1 (fr) 1991-03-05
NZ232023A (en) 1992-05-26

Similar Documents

Publication Publication Date Title
ATE98231T1 (de) Piperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.
DK0687253T3 (da) Hidtil ukendte 4-aminopyridiner, fremgangsmåde til deres fremstilling samt lægemidler indeholdende disse forbindelser
ATE144503T1 (de) Thiazolidin-2,4-dionderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
NO975987L (no) 4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater
ATE125252T1 (de) Cyano-2-hydroxy-3-enamid-derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte.
CA2238817A1 (en) 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
AR012102A1 (es) Derivados de 2-(iminometil)amino-fenilo, su preparacion, uso de los mismos para la fabricacion de medicamentos y composiciones farmaceuticas que los contienen.
GB1014053A (en) 7-hydroxy-coumarin derivatives and process for their production
ATE101612T1 (de) Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel.
HUT46003A (en) Process for producing 3,7-dihydro-3-methyl-7-square brackets open (1,2,4-oxadiazol-3-yl)-alkylinyl square brackets closed -1h-purine-2,6-dione derivatives and pharmaceutics comprising such compounds
ATE86602T1 (de) Alpha,alpha disubstituierte n-cycloalkylalkylbenzylamine, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und ihre zwischenprodukte bei der herstellung.
ATE19776T1 (de) Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE111909T1 (de) Heterocyclisch substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln.
ATE3548T1 (de) Neue, in 5-stellung substituierte 5,10-dihydro11h-dibenzo (b,e)(1,4)diazepin-11-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
IE38907L (en) Tetrahydropyridine and piperidine derivatives.
KR930004234A (ko) 메타노안트라센 화합물
FI873183A0 (fi) Komplex med optiskt aktiva sockerligander, foerfarande foer deras framstaellning och deras anvaendning.
ATE139532T1 (de) Neue dna-gyrase inhibitoren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATE34170T1 (de) 1-(3-(6-fluor-1,2-benzisoxazol-3-yl)propyl)-4(substituierte)-piperazine und -piperidine, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen und ihre verwendung als arzneimittel.
DE60220779D1 (de) Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten
ATE96434T1 (de) 2-(heteroalkyl)-1,4-dihydropyridine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE325793T1 (de) Benzyliden-gamma-butyrolactone, verfahren zu ihrer herstellung und ihre verwendung als uv- absorber
DE69207609D1 (de) 4-cinnolinon-derivate, ihre herstellung und ihre verwendung als arzneimittel
DE68907857D1 (de) Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3671221D1 (de) Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee