NO900019L - Piperidiner og fremgangsmaate til fremstilling derav. - Google Patents

Piperidiner og fremgangsmaate til fremstilling derav.

Info

Publication number: NO900019L
Authority: NO; Norway
Prior art keywords: group; fluorobenzoyl; piperidyl; piperidines; nitrogen atom
Prior art date: 1989-01-05

Application number

NO90900019A

Other languages

English (en)

Norwegian (no)

Other versions

NO900019D0 (no

Inventor

Gerard Ferrand

Herve Dumas

Jean-Claude Depin

Gilles Chavernac

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-05

Filing date

1990-01-04

Publication date

1990-07-06

1990-01-04 Application filed by Lipha filed Critical Lipha

1990-01-04 Publication of NO900019D0 publication Critical patent/NO900019D0/no

1990-07-06 Publication of NO900019L publication Critical patent/NO900019L/no

Links

150000003053 piperidines Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
-1 4-fluorobenzoyl Chemical group 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
KZKRRZFCAYOXQE-UHFFFAOYSA-N 1$l^{2}-azinane Chemical compound C1CC[N]CC1 KZKRRZFCAYOXQE-UHFFFAOYSA-N 0.000 abstract 1
125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 abstract 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

NO90900019A 1989-01-05 1990-01-04 Piperidiner og fremgangsmaate til fremstilling derav. NO900019L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8900071A FR2641278B1 (fr)	1989-01-05	1989-01-05	Piperidines, procedes de preparation et medicaments les contenant

Publications (2)

Publication Number	Publication Date
NO900019D0 NO900019D0 (no)	1990-01-04
NO900019L true NO900019L (no)	1990-07-06

Family

ID=9377487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO90900019A NO900019L (no)	1989-01-05	1990-01-04	Piperidiner og fremgangsmaate til fremstilling derav.

Country Status (23)

Country	Link
US (1)	US5001134A (de)
EP (1)	EP0377528B1 (de)
JP (1)	JP2927480B2 (de)
AT (1)	ATE98231T1 (de)
AU (1)	AU634739B2 (de)
CA (1)	CA2007127A1 (de)
DD (1)	DD291323A5 (de)
DE (1)	DE69004973T2 (de)
DK (1)	DK0377528T3 (de)
ES (1)	ES2062425T3 (de)
FR (1)	FR2641278B1 (de)
HU (1)	HUT58053A (de)
IL (1)	IL92950A0 (de)
MA (1)	MA21719A1 (de)
MX (1)	MX26760A (de)
NO (1)	NO900019L (de)
NZ (1)	NZ232023A (de)
OA (1)	OA09433A (de)
PT (1)	PT92782A (de)
RU (1)	RU1838299C (de)
TN (1)	TNSN90002A1 (de)
YU (1)	YU2290A (de)
ZA (1)	ZA9061B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5776963A (en) *	1989-05-19	1998-07-07	Hoechst Marion Roussel, Inc.	3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5561128A (en) *	1989-05-19	1996-10-01	Hoechst-Roussel Pharmaceuticals, Inc.	N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5364866A (en) *	1989-05-19	1994-11-15	Hoechst-Roussel Pharmaceuticals, Inc.	Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
AU672182B2 (en) *	1991-11-27	1996-09-26	Novo Nordisk A/S	Piperidine derivatives and their use in treating psychosis
US5378714A (en) *	1991-11-27	1995-01-03	Novo Nordisk A/S	Antipsychotic piperidine derivatives
WO1994006765A1 (fr) *	1992-09-17	1994-03-31	Nippon Soda Co., Ltd.	Compose heterocyclique azote, son procede de production, et agent de lutte contre les parasites
US5512591A (en) *	1993-02-18	1996-04-30	President And Fellows Of Harvard College	Treatments for diseases characterized by neovascularization
US5633274A (en) *	1993-02-18	1997-05-27	President And Fellows Of Harvard College	Cancer treatments
DK60593D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60793D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60693D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60893D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Piperidinderivater, deres fremstilling og anvendelse
US5453425A (en) *	1994-07-11	1995-09-26	Janssen Pharmaceutica N.V.	Risperidone oral formulation
US5556871A (en) *	1995-04-24	1996-09-17	President & Fellows Of Harvard College	Method for treating epithelial precancerous lesions with topical inidazoles
CA2350730A1 (en) *	1998-12-18	2000-06-22	George V. Delucca	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6605623B1 (en) *	1998-12-18	2003-08-12	Bristol-Myers Squibb Pharma Co.	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
WO2000035449A1 (en) *	1998-12-18	2000-06-22	Du Pont Pharmaceuticals Company	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6486180B1 (en) *	1998-12-18	2002-11-26	Bristol-Myers Squibb Pharma Company	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US7166617B2 (en) *	2000-02-29	2007-01-23	Mitsubishi Pharma Corporation	Cyclic amide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4355037A (en) *	1981-11-12	1982-10-19	Hoechst-Roussel Pharmaceuticals	3-(4-Piperidyl)-1,2-benzisoxales
FR2527205A1 (fr) *	1982-05-18	1983-11-25	Bouchara Emile	Nouvelles phenyloxoalcoyl piperidines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
US4804663A (en) *	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

1989
- 1989-01-05 FR FR8900071A patent/FR2641278B1/fr not_active Expired - Lifetime
1990
- 1990-01-02 IL IL92950A patent/IL92950A0/xx unknown
- 1990-01-03 ES ES90400006T patent/ES2062425T3/es not_active Expired - Lifetime
- 1990-01-03 MA MA21979A patent/MA21719A1/fr unknown
- 1990-01-03 EP EP90400006A patent/EP0377528B1/de not_active Expired - Lifetime
- 1990-01-03 AT AT90400006T patent/ATE98231T1/de not_active IP Right Cessation
- 1990-01-03 DE DE69004973T patent/DE69004973T2/de not_active Expired - Fee Related
- 1990-01-03 DK DK90400006.4T patent/DK0377528T3/da active
- 1990-01-04 NO NO90900019A patent/NO900019L/no unknown
- 1990-01-04 HU HU9039A patent/HUT58053A/hu unknown
- 1990-01-04 CA CA002007127A patent/CA2007127A1/fr not_active Abandoned
- 1990-01-04 MX MX2676090A patent/MX26760A/es unknown
- 1990-01-04 PT PT92782A patent/PT92782A/pt unknown
- 1990-01-04 DD DD90336942A patent/DD291323A5/de not_active IP Right Cessation
- 1990-01-04 RU SU904742892A patent/RU1838299C/ru active
- 1990-01-04 JP JP2000045A patent/JP2927480B2/ja not_active Expired - Lifetime
- 1990-01-04 ZA ZA9061A patent/ZA9061B/xx unknown
- 1990-01-05 OA OA59722A patent/OA09433A/xx unknown
- 1990-01-05 AU AU47713/90A patent/AU634739B2/en not_active Expired - Fee Related
- 1990-01-05 YU YU00022/90A patent/YU2290A/xx unknown
- 1990-01-05 TN TNTNSN90002A patent/TNSN90002A1/fr unknown
- 1990-01-05 US US07/461,515 patent/US5001134A/en not_active Expired - Lifetime
- 1990-01-05 NZ NZ232023A patent/NZ232023A/en unknown

Also Published As

Publication number	Publication date
OA09433A (fr)	1992-10-15
ATE98231T1 (de)	1993-12-15
DD291323A5 (de)	1991-06-27
DK0377528T3 (da)	1994-04-11
NO900019D0 (no)	1990-01-04
ZA9061B (en)	1990-10-31
US5001134A (en)	1991-03-19
IL92950A0 (en)	1990-09-17
JPH02225465A (ja)	1990-09-07
PT92782A (pt)	1990-07-31
DE69004973T2 (de)	1994-06-23
DE69004973D1 (de)	1994-01-20
HU900039D0 (en)	1990-03-28
EP0377528B1 (de)	1993-12-08
EP0377528A1 (de)	1990-07-11
NZ232023A (en)	1992-05-26
AU4771390A (en)	1990-07-12
JP2927480B2 (ja)	1999-07-28
TNSN90002A1 (fr)	1991-03-05
RU1838299C (ru)	1993-08-30
AU634739B2 (en)	1993-03-04
FR2641278B1 (fr)	1991-03-22
MA21719A1 (fr)	1990-10-01
MX26760A (es)	1994-02-28
ES2062425T3 (es)	1994-12-16
FR2641278A1 (fr)	1990-07-06
HUT58053A (en)	1992-01-28
YU2290A (en)	1992-05-28
CA2007127A1 (fr)	1990-07-05

Publication	Publication Date	Title
NO900019L (no)	1990-07-06	Piperidiner og fremgangsmaate til fremstilling derav.
DK0646115T3 (da)	2003-04-22	Heterocykliske/cykliske aminderivater
DK131893D0 (da)	1993-11-24	2-(substitueret methyl)-4-(substitueret ethoxy)-5-(lavere alkyl)-pyridinforbindelser, farmaceutisk praeparat, som indeholder saadanne samt anvendelse af en saadan forbindelse til fremstilling af et farmaceutisk praeparat
BR1100931A (pt)	1999-11-23	Compostos derivados de aril-heteroaril carbinóis, processos para a preparação dos compostos, composições farmacêuticas, e, uso dos compostos derivados de aril-heteroaril carbinóis
FI952850A7 (fi)	1995-06-09	Menetelmä lääkeaineena käyttökelpoisen syklisen amiiniyhdisteen tai sen farmaseuttisen suolan valmistamiseksi
ATE206122T1 (de)	2001-10-15	Verbindungen, die als antiproliferative mittel und als garft inhibitoren verwendbar sind
CA2238817A1 (en)	1997-07-10	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
AR012102A1 (es)	2000-09-27	Derivados de 2-(iminometil)amino-fenilo, su preparacion, uso de los mismos para la fabricacion de medicamentos y composiciones farmaceuticas que los contienen.
NO905368D0 (no)	1990-12-12	Serotonin-antagonister, deres fremstilling og anvendelse.
DK0532515T3 (da)	1997-04-21	Fremstilling af substituerede piperidiner
HUP0402261A2 (hu)	2005-02-28	Piperidinszármazékok és alkalmazásuk kemokin receptor aktivitás modulátoraiként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
KR930004262A (ko)	1993-03-22	메타노안트라센 화합물
ATE128463T1 (de)	1995-10-15	Piperidin und pyrrolidin derivate.
DK326481A (da)	1982-01-25	Fremgangsmaade til fremstilling af i 5-stillingen substituerede 5,10-dihydro-11h-dibenzo (b,e) (1,4) diazepin-11-oner eller syreadditionssalte deraf
NO20022123L (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
NO20002351L (no)	2000-11-06	Nye substituerte pyridin- eller piperidinforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem
KR930004234A (ko)	1993-03-22	메타노안트라센 화합물
KR930700441A (ko)	1993-03-15	1-피페리디닐 알카노일아릴 술폰아미드 유도체
ATE92058T1 (de)	1993-08-15	Pyrimidin-derivate, 2-(4-(alpha-heteroaryl-alphaaryl-(alpha-alkyl)-methoxy)-butyl)-1-piperaziny > mit serotoninergischer wirkung.
DK104388D0 (da)	1988-02-26	Hidtil ukendte 2-(2,3-dihydro-2-oxo-3-benzofuranyl)-eddikesyrederivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
RU2000111489A (ru)	2002-05-10	Антипсихотические замещенные производные пиперидина
ES444064A1 (es)	1977-08-16	Procedimiento de preparacion de nuevos (aroil-2'-et-1'-il)- 1-(acetamido-4"-piperazin-1"-il-metil)-2-bencimidazoles.