YU2290A - Process for piperidine obtaining - Google Patents

Process for piperidine obtaining

Info

Publication number: YU2290A
Authority: YU; Yugoslavia
Prior art keywords: group; fluorobenzoyl; piperidyl; nitrogen atom; radical
Prior art date: 1989-01-05

Application number

YU00022/90A

Other languages

English (en)

Inventor

G Ferrand

J C Depin

G Chavernac

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-05

Filing date

1990-01-05

Publication date

1992-05-28

1990-01-05 Application filed by Lipha filed Critical Lipha

1992-05-28 Publication of YU2290A publication Critical patent/YU2290A/xx

Links

NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 2
-1 4-fluorobenzoyl Chemical group 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
KZKRRZFCAYOXQE-UHFFFAOYSA-N 1$l^{2}-azinane Chemical compound C1CC[N]CC1 KZKRRZFCAYOXQE-UHFFFAOYSA-N 0.000 abstract 1
125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 abstract 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
150000003053 piperidines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

YU00022/90A 1989-01-05 1990-01-05 Process for piperidine obtaining YU2290A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8900071A FR2641278B1 (fr)	1989-01-05	1989-01-05	Piperidines, procedes de preparation et medicaments les contenant

Publications (1)

Publication Number	Publication Date
YU2290A true YU2290A (en)	1992-05-28

Family

ID=9377487

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU00022/90A YU2290A (en)	1989-01-05	1990-01-05	Process for piperidine obtaining

Country Status (23)

Country	Link
US (1)	US5001134A (de)
EP (1)	EP0377528B1 (de)
JP (1)	JP2927480B2 (de)
AT (1)	ATE98231T1 (de)
AU (1)	AU634739B2 (de)
CA (1)	CA2007127A1 (de)
DD (1)	DD291323A5 (de)
DE (1)	DE69004973T2 (de)
DK (1)	DK0377528T3 (de)
ES (1)	ES2062425T3 (de)
FR (1)	FR2641278B1 (de)
HU (1)	HUT58053A (de)
IL (1)	IL92950A0 (de)
MA (1)	MA21719A1 (de)
MX (1)	MX26760A (de)
NO (1)	NO900019L (de)
NZ (1)	NZ232023A (de)
OA (1)	OA09433A (de)
PT (1)	PT92782A (de)
RU (1)	RU1838299C (de)
TN (1)	TNSN90002A1 (de)
YU (1)	YU2290A (de)
ZA (1)	ZA9061B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5364866A (en) *	1989-05-19	1994-11-15	Hoechst-Roussel Pharmaceuticals, Inc.	Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) *	1989-05-19	1998-07-07	Hoechst Marion Roussel, Inc.	3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5561128A (en) *	1989-05-19	1996-10-01	Hoechst-Roussel Pharmaceuticals, Inc.	N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5378714A (en) *	1991-11-27	1995-01-03	Novo Nordisk A/S	Antipsychotic piperidine derivatives
NZ245260A (en) *	1991-11-27	1995-06-27	Novo Nordisk As	Piperidine derivatives, preparation and pharmaceutical compositions thereof
AU4984293A (en) *	1992-09-17	1994-04-12	Nippon Soda Co., Ltd.	Nitrogenous heterocyclic compound, process for producing the same, and pest control agent
US5512591A (en) *	1993-02-18	1996-04-30	President And Fellows Of Harvard College	Treatments for diseases characterized by neovascularization
US5633274A (en) *	1993-02-18	1997-05-27	President And Fellows Of Harvard College	Cancer treatments
DK60793D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60693D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60593D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Kemiske forbindelser, deres fremstilling og anvendelse
DK60893D0 (da) *	1993-05-26	1993-05-26	Novo Nordisk As	Piperidinderivater, deres fremstilling og anvendelse
US5453425A (en) *	1994-07-11	1995-09-26	Janssen Pharmaceutica N.V.	Risperidone oral formulation
US5556871A (en) *	1995-04-24	1996-09-17	President & Fellows Of Harvard College	Method for treating epithelial precancerous lesions with topical inidazoles
EP1156807A4 (de) *	1998-12-18	2002-04-03	Du Pont Pharm Co	N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
AU2057200A (en) *	1998-12-18	2000-07-03	Du Pont Pharmaceuticals Company	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
CA2347909A1 (en) *	1998-12-18	2000-06-22	Joseph B. Santella, Iii	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6605623B1 (en) *	1998-12-18	2003-08-12	Bristol-Myers Squibb Pharma Co.	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
IL151533A0 (en) *	2000-02-29	2003-04-10	Mitsubishi Pharma Corp	Novel cyclic amide derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4355037A (en) *	1981-11-12	1982-10-19	Hoechst-Roussel Pharmaceuticals	3-(4-Piperidyl)-1,2-benzisoxales
FR2527205A1 (fr) *	1982-05-18	1983-11-25	Bouchara Emile	Nouvelles phenyloxoalcoyl piperidines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
US4804663A (en) *	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

1989
- 1989-01-05 FR FR8900071A patent/FR2641278B1/fr not_active Expired - Lifetime
1990
- 1990-01-02 IL IL92950A patent/IL92950A0/xx unknown
- 1990-01-03 MA MA21979A patent/MA21719A1/fr unknown
- 1990-01-03 ES ES90400006T patent/ES2062425T3/es not_active Expired - Lifetime
- 1990-01-03 DK DK90400006.4T patent/DK0377528T3/da active
- 1990-01-03 AT AT90400006T patent/ATE98231T1/de not_active IP Right Cessation
- 1990-01-03 DE DE69004973T patent/DE69004973T2/de not_active Expired - Fee Related
- 1990-01-03 EP EP90400006A patent/EP0377528B1/de not_active Expired - Lifetime
- 1990-01-04 JP JP2000045A patent/JP2927480B2/ja not_active Expired - Lifetime
- 1990-01-04 RU SU904742892A patent/RU1838299C/ru active
- 1990-01-04 ZA ZA9061A patent/ZA9061B/xx unknown
- 1990-01-04 DD DD90336942A patent/DD291323A5/de not_active IP Right Cessation
- 1990-01-04 PT PT92782A patent/PT92782A/pt unknown
- 1990-01-04 MX MX2676090A patent/MX26760A/es unknown
- 1990-01-04 HU HU9039A patent/HUT58053A/hu unknown
- 1990-01-04 NO NO90900019A patent/NO900019L/no unknown
- 1990-01-04 CA CA002007127A patent/CA2007127A1/fr not_active Abandoned
- 1990-01-05 US US07/461,515 patent/US5001134A/en not_active Expired - Lifetime
- 1990-01-05 AU AU47713/90A patent/AU634739B2/en not_active Expired - Fee Related
- 1990-01-05 YU YU00022/90A patent/YU2290A/xx unknown
- 1990-01-05 TN TNTNSN90002A patent/TNSN90002A1/fr unknown
- 1990-01-05 OA OA59722A patent/OA09433A/xx unknown
- 1990-01-05 NZ NZ232023A patent/NZ232023A/en unknown

Also Published As

Publication number	Publication date
JPH02225465A (ja)	1990-09-07
HU900039D0 (en)	1990-03-28
HUT58053A (en)	1992-01-28
EP0377528B1 (de)	1993-12-08
FR2641278B1 (fr)	1991-03-22
AU4771390A (en)	1990-07-12
MA21719A1 (fr)	1990-10-01
JP2927480B2 (ja)	1999-07-28
ES2062425T3 (es)	1994-12-16
MX26760A (es)	1994-02-28
NO900019L (no)	1990-07-06
DK0377528T3 (da)	1994-04-11
RU1838299C (ru)	1993-08-30
NO900019D0 (no)	1990-01-04
CA2007127A1 (fr)	1990-07-05
US5001134A (en)	1991-03-19
FR2641278A1 (fr)	1990-07-06
NZ232023A (en)	1992-05-26
AU634739B2 (en)	1993-03-04
EP0377528A1 (de)	1990-07-11
PT92782A (pt)	1990-07-31
DD291323A5 (de)	1991-06-27
DE69004973D1 (de)	1994-01-20
ZA9061B (en)	1990-10-31
ATE98231T1 (de)	1993-12-15
DE69004973T2 (de)	1994-06-23
TNSN90002A1 (fr)	1991-03-05
OA09433A (fr)	1992-10-15
IL92950A0 (en)	1990-09-17

Publication	Publication Date	Title
NO900019L (no)	1990-07-06	Piperidiner og fremgangsmaate til fremstilling derav.
EG20281A (en)	1998-07-30	Process for preparing heterocyclic cyclic amine derivatives useful in enhancing memory in patients suffering from dementia and alzheimer's disease
FI952850A7 (fi)	1995-06-09	Menetelmä lääkeaineena käyttökelpoisen syklisen amiiniyhdisteen tai sen farmaseuttisen suolan valmistamiseksi
NO953447L (no)	1995-09-01	Nye 4-aminopyridiner, fremgangsmåte for deres fremstilling samt legemidler inneholdende disse
CA2238817A1 (en)	1997-07-10	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
BR1100931A (pt)	1999-11-23	Compostos derivados de aril-heteroaril carbinóis, processos para a preparação dos compostos, composições farmacêuticas, e, uso dos compostos derivados de aril-heteroaril carbinóis
ATE101612T1 (de)	1994-03-15	Serotonin-antagonisten, ihre herstellung und sie enthaltende arzneimittel.
CA2067758A1 (en)	1991-07-07	Piperidine and pyrrolidine derivatives
GB1429751A (en)	1976-03-24	Preparations for inhibiting emesis
KR930004234A (ko)	1993-03-22	메타노안트라센 화합물
NZ335631A (en)	2000-10-27	Antipsychotic (neuroleptic) piperidine derivatives
HUT35670A (en)	1985-07-29	Process for preparing indole derivatives and pharmaceutical compositions containing sucg compounds
ATE96434T1 (de)	1993-11-15	2-(heteroalkyl)-1,4-dihydropyridine, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DK241188A (da)	1988-11-27	Fremgangsmaade til fremstilling af alfa-(alkylphenyl)-4-(hydroxydiphenyl-methyl)-1-piperidin-butanol og mellemprodukt til brug ved fremgangsmaaden
GR880100111A (en)	1988-12-16	Preparation method of new derivatives of (dihydro-2,3 oxo-2 benzofuranil-3)-2 of acetic acid
NO871140D0 (no)	1987-03-19	Fremgangsmaate ved fremstilling av nye 1- (3-(2-(4-morfolinyl)-etoksy)-(2-dialkylaminoetoksy)-2-tienyl)-3-fenyl-propanoner og syreaddisjonssalter derav.
NZ535476A (en)	2006-03-31	4-(diarylmethyl)-1-piperazinyl derivatives
ES444064A1 (es)	1977-08-16	Procedimiento de preparacion de nuevos (aroil-2'-et-1'-il)- 1-(acetamido-4"-piperazin-1"-il-metil)-2-bencimidazoles.
TH9795A (th)	1991-11-01	1-(1h-อิมิดาซอล-4-อิล)อัลคิลเบนซามีตที่ถูกแทนที่
NO954070L (no)	1995-10-13	Fremgangsmåte for fremstilling av
TH19231A (th)	1996-06-21	วิธีลดโคเลสเทอรอลในซีรัม