BE1000201A4 - Composes antibiotiques, leur preparation et les compositions pharmaceutiques qui les contiennent. - Google Patents

Composes antibiotiques, leur preparation et les compositions pharmaceutiques qui les contiennent.

Info

Publication number
BE1000201A4
BE1000201A4 BE8700626A BE8700626A BE1000201A4 BE 1000201 A4 BE1000201 A4 BE 1000201A4 BE 8700626 A BE8700626 A BE 8700626A BE 8700626 A BE8700626 A BE 8700626A BE 1000201 A4 BE1000201 A4 BE 1000201A4
Authority
BE
Belgium
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
antibiotic compounds
compounds
Prior art date
Application number
BE8700626A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868613790A external-priority patent/GB8613790D0/en
Priority claimed from GB868625854A external-priority patent/GB8625854D0/en
Priority claimed from GB878708423A external-priority patent/GB8708423D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of BE1000201A4 publication Critical patent/BE1000201A4/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne de nouveaux macrolides. Ces composés répondent à la formule (I), et leur sels, où R1 = méthyl, éthyle ou isopropyle;R2 représente H, alkyle en C1-C8 ou alcényle en C3-C8 et =NOR2 est en configuration E; OR3 est hydroxyle ou hydroxyle substitué avec jusqu'à 25 atomes de carbone. Ces composés sont intéressants pour lutter contre des insectes, des acariens, des nématodes ou d'autres parasites.
BE8700626A 1986-06-06 1987-06-05 Composes antibiotiques, leur preparation et les compositions pharmaceutiques qui les contiennent. BE1000201A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868613790A GB8613790D0 (en) 1986-06-06 1986-06-06 Chemical compounds
GB868625854A GB8625854D0 (en) 1986-10-29 1986-10-29 Chemical process
GB878708423A GB8708423D0 (en) 1987-04-08 1987-04-08 Chemical compounds

Publications (1)

Publication Number Publication Date
BE1000201A4 true BE1000201A4 (fr) 1988-08-23

Family

ID=27263057

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700626A BE1000201A4 (fr) 1986-06-06 1987-06-05 Composes antibiotiques, leur preparation et les compositions pharmaceutiques qui les contiennent.

Country Status (35)

Country Link
US (1) US4900753A (fr)
JP (1) JP2648147B2 (fr)
KR (1) KR950010077B1 (fr)
CN (1) CN1023858C (fr)
AR (1) AR244691A1 (fr)
AT (1) AT398571B (fr)
AU (1) AU609399B2 (fr)
BE (1) BE1000201A4 (fr)
BR (1) BR8702866A (fr)
CA (1) CA1296329C (fr)
CH (1) CH677670A5 (fr)
DE (3) DE3718926C2 (fr)
DK (1) DK166498B1 (fr)
EG (1) EG18752A (fr)
ES (1) ES2006479A6 (fr)
FI (2) FI90663C (fr)
FR (1) FR2599742B1 (fr)
GB (1) GB2192630B (fr)
GE (1) GEP19981388B (fr)
GR (1) GR870891B (fr)
HU (1) HU199847B (fr)
IE (1) IE60411B1 (fr)
IL (1) IL82776A (fr)
IT (1) IT1206015B (fr)
LU (2) LU86908A1 (fr)
LV (2) LV10280A (fr)
NL (2) NL193376C (fr)
NZ (1) NZ220587A (fr)
OA (1) OA08606A (fr)
PH (1) PH23948A (fr)
PL (3) PL153036B1 (fr)
PT (1) PT85018B (fr)
SE (1) SE503399C2 (fr)
TR (1) TR28970A (fr)
UA (1) UA45300C2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260537A1 (fr) * 1986-09-12 1988-03-23 American Cyanamid Company Dérivés 13-déoxy-23-oxo(céto) et 23-imino des composés de 13-déoxy-C-076-aglycone
ATE109783T1 (de) * 1986-09-12 1994-08-15 American Cyanamid Co 23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8905605D0 (en) * 1989-03-11 1989-04-26 Beecham Group Plc Novel compounds
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds
EP0561990B1 (fr) * 1990-12-07 1998-10-07 Temple University Compositions insecticides stabilisees contenant des nematodes
JP2855181B2 (ja) 1993-12-10 1999-02-10 敏雄 鈴木 松類の枯損防止用組成物及び防止方法
PT1197215E (pt) 2000-10-10 2006-07-31 Wyeth Corp Composicoes antelminticas
US7348417B2 (en) * 2003-08-07 2008-03-25 Wyeth Method of purifying moxidectin through crystallization
WO2006119174A1 (fr) 2005-04-30 2006-11-09 Ocular Surface Center, P.A. Methode de traitement oculaire de demodex
JP4939025B2 (ja) * 2005-09-30 2012-05-23 三菱電線工業株式会社 電熱ヒータ付きハンドル用グリップ部材
EP1849363A1 (fr) * 2006-03-09 2007-10-31 Cheminova A/S Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
US8128968B2 (en) * 2007-08-29 2012-03-06 Tissuetech, Inc. Compositions and methods for treating Demodex infestations
WO2013082373A1 (fr) 2011-12-02 2013-06-06 Merial Limited Formulations de moxidectine injectable à action prolongée et nouveau cristal de moxidectine
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
EP0110667A1 (fr) * 1982-11-25 1984-06-13 Sankyo Company Limited Dérivés de la didéhydromilbémycine, leur préparation et les compositions les contenant
EP0170006A2 (fr) * 1984-06-05 1986-02-05 American Cyanamid Company Agents et leurs méthodes de production, méthodes et compositions contenant ces agents pour lutter contre les infections dûes aux helminthes, aux arthropodes, aux ectoparasites et aux acariens
FR2570390A1 (fr) * 1984-09-14 1986-03-21 Glaxo Group Ltd Nouveaux composes antibiotiques et procede de preparation
GB2176182A (en) * 1985-04-30 1986-12-17 Glaxo Group Ltd Macrolide antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
ATE109783T1 (de) * 1986-09-12 1994-08-15 American Cyanamid Co 23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
EP0110667A1 (fr) * 1982-11-25 1984-06-13 Sankyo Company Limited Dérivés de la didéhydromilbémycine, leur préparation et les compositions les contenant
EP0170006A2 (fr) * 1984-06-05 1986-02-05 American Cyanamid Company Agents et leurs méthodes de production, méthodes et compositions contenant ces agents pour lutter contre les infections dûes aux helminthes, aux arthropodes, aux ectoparasites et aux acariens
FR2570390A1 (fr) * 1984-09-14 1986-03-21 Glaxo Group Ltd Nouveaux composes antibiotiques et procede de preparation
GB2176182A (en) * 1985-04-30 1986-12-17 Glaxo Group Ltd Macrolide antibiotics

Also Published As

Publication number Publication date
LU88790I2 (fr) 1997-03-18
FR2599742B1 (fr) 1989-05-19
FI923445A0 (fi) 1992-07-30
PL266100A1 (en) 1988-07-21
DE3745133C2 (de) 1998-01-02
SE8702361D0 (sv) 1987-06-05
NZ220587A (en) 1990-05-28
LV10280A (lv) 1994-10-20
NL990026I2 (nl) 1999-12-01
TR28970A (tr) 1997-07-21
DE3718926C2 (de) 1998-01-15
KR950010077B1 (ko) 1995-09-06
GB2192630B (en) 1990-05-23
PT85018A (en) 1987-07-01
HUT44254A (en) 1988-02-29
PL153226B1 (en) 1991-03-29
DK290287A (da) 1987-12-07
SE503399C2 (sv) 1996-06-10
CH677670A5 (fr) 1991-06-14
GEP19981388B (en) 1998-11-10
DK166498B1 (da) 1993-06-01
IL82776A (en) 1992-02-16
FI90663C (fi) 1994-03-10
GB2192630A (en) 1988-01-20
FR2599742A1 (fr) 1987-12-11
US4900753A (en) 1990-02-13
CA1296329C (fr) 1992-02-25
EG18752A (en) 1993-12-30
NL193376C (nl) 1999-08-03
JPS6354375A (ja) 1988-03-08
PL153036B1 (en) 1991-02-28
CN1023858C (zh) 1994-02-23
FI923445L (fi) 1992-07-30
PL155723B1 (en) 1991-12-31
LU86908A1 (fr) 1988-01-20
GB8713239D0 (en) 1987-07-08
FI90663B (fi) 1993-11-30
DE19875029I2 (de) 2001-11-22
AR244691A1 (es) 1993-11-30
ES2006479A6 (es) 1989-05-01
NL990026I1 (nl) 1999-11-01
BR8702866A (pt) 1988-03-01
FI90549C (fi) 1994-02-25
KR880000441A (ko) 1988-03-25
ATA143887A (de) 1994-05-15
FI90549B (fi) 1993-11-15
IE871496L (en) 1987-12-06
PH23948A (en) 1990-01-23
SE8702361L (sv) 1987-12-07
AT398571B (de) 1994-12-27
HU199847B (en) 1990-03-28
NL8701322A (nl) 1988-01-04
UA45300C2 (uk) 2002-04-15
LV10781B (en) 1996-10-20
PT85018B (pt) 1990-03-08
FI872517A7 (fi) 1987-12-07
IE60411B1 (en) 1994-07-13
OA08606A (en) 1988-11-30
IT8748023A0 (it) 1987-06-05
FI872517A0 (fi) 1987-06-04
DE3718926A1 (de) 1987-12-10
IT1206015B (it) 1989-04-05
GR870891B (en) 1987-10-02
NL193376B (nl) 1999-04-01
JP2648147B2 (ja) 1997-08-27
IL82776A0 (en) 1987-12-20
AU7387387A (en) 1987-12-10
LV10781A (lv) 1995-08-20
CN87104431A (zh) 1987-12-30
AU609399B2 (en) 1991-05-02
DK290287D0 (da) 1987-06-04

Similar Documents

Publication Publication Date Title
BE1000201A4 (fr) Composes antibiotiques, leur preparation et les compositions pharmaceutiques qui les contiennent.
BE1002211A4 (fr) (pentamethyl-1,2,2,6,6 piperidyl-4-amino)-triazines, leur application comme stabilisants de matieres organiques, et compositions qui en contiennent.
KR850002964A (ko) 심장병 치료제의 제조방법
KR930016436A (ko) 4, 13-디옥사바이사이클로[8.2.1]트리데세논유도체와 그의 제조방법, 그의 제조를 위한 중간체 및 이화합물이 함유된 약학조성물
KR910002800A (ko) 4-아실록시퀴놀린 유도체와 이를 함유하는 살충 또는 살비조성물
AU7042381A (en) Aminopropiophenone derivatives
ES8802156A1 (es) Procedimiento para la obtencion de derivados de la 13-beta-milbemicina
KR890011872A (ko) 인돌일 피페리딘 화합물, 그 제조방법 및 그들을 함유하는 약학조성물
KR910000751A (ko) 세펨 화합물 및 이의 제조방법
IL69882A (en) Analgesia-effecting 5-hydroxytryptophan derivatives and pharmaceutical compositions comprising them
KR890009962A (ko) 매뉴마이신 유도체, 이의 제조방법 및 용도
NZ219576A (en) Milbemycin derivatives and pharmaceutical, veterinary, and pesticidal compositions
CA2064108A1 (fr) Derives de la thiazolidinone et de l'oxazolidinone, leur preparation et leur utilisation comme vasodilatateurs
ATE94879T1 (de) Makrolid-verbindungen.
KR890009901A (ko) 3-히드록시-2-(4-메톡시페닐)-5-(2-메틸아미노에틸)-2,3-디히드로-5h-1,5- 벤조티아제핀-4-온 유도체, 그의 제조 및 치료에의 이용
IE890259L (en) Macrolide compounds
IE55871B1 (en) Thieno-thiazole derivatives
KR890005076A (ko) 티아디아진 유도체, 그의 제조방법 및 그 화합물을 함유하는 살충제
FI873800A0 (fi) Nor-kolansyraderivat, foerfarande foer deras framstaellning, deras anvaendning samt farmaceutiska kompositioner innehaollande desamma.
IE792167L (en) Benzazepinones
KR830001900A (ko) 페닐모르판과 그의 중간물질및 제조방법
BE1002181A3 (fr) 3-(2-haloalkyl)-1,4-oxathiines et 2-(2-haloalkyl)-1,4-dithiines, de meme que le traitement de la leucemie et des tumeurs avec ces substances.
EP0246171A3 (fr) Compositions fongicides à base de dérivés nicotiniques, nouveaux dérivés nicotiniques et leur préparation
KR890017251A (ko) 마크롤리드 화합물
AU5826986A (en) Banzaldoxime carbamate derivative

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: *WYETH HOLDINGS CORPORATION

Effective date: 20070605

CCRE Expiry of a supplementary protection certificate

Free format text: PRODUCT NAME: MOXIDECTIN GT 90% POTENCY; NAT. REGISTRATION NO/DATE: 536 IS 140 F12 19950904; FIRST REGISTRATION: FR 673260.3 19941230

Spc suppl protection certif: 96C0008

Filing date: 19961217

Expiry date: 20070605

Extension date: 20091230

Effective date: 20091230

RE20 Patent expired

Owner name: *WYETH HOLDINGS CORPORATION

Free format text: SPC 096C0008

Effective date: 20091230