BE1002201A5 - Compositions pharmaceutiques. - Google Patents
Compositions pharmaceutiques. Download PDFInfo
- Publication number
- BE1002201A5 BE1002201A5 BE8900312A BE8900312A BE1002201A5 BE 1002201 A5 BE1002201 A5 BE 1002201A5 BE 8900312 A BE8900312 A BE 8900312A BE 8900312 A BE8900312 A BE 8900312A BE 1002201 A5 BE1002201 A5 BE 1002201A5
- Authority
- BE
- Belgium
- Prior art keywords
- solution
- pharmaceutical compositions
- way
- chlorbutol
- nebulization
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000006673 asthma Diseases 0.000 abstract 2
- OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 abstract 1
- 229960004926 chlorobutanol Drugs 0.000 abstract 1
- 230000001143 conditioned effect Effects 0.000 abstract 1
- 229960000265 cromoglicic acid Drugs 0.000 abstract 1
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical compound O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000024711 extrinsic asthma Diseases 0.000 abstract 1
- 201000010659 intrinsic asthma Diseases 0.000 abstract 1
- 238000002663 nebulization Methods 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 230000002441 reversible effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Une solution d'un médicament pour inhalation est conditionnée dans un distributeur scellé contenant un gaz sous pression et muni d'une valve de sortie unidirectionnelle. Le distributeur permet de débiter des aliquotes de la solution qui est ensuite administrée par nébulisation. Une solution de cromoglycate de sodium et de chlorbutol conditionnée de la sorte est préférée pour le traitement de l'obstruction réversible des voies respiratoires, par exemple de l'asthme extrinsèque ou intrinsèque.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888806818A GB8806818D0 (en) | 1988-03-22 | 1988-03-22 | Pharmaceutical formulation |
| GB888819490A GB8819490D0 (en) | 1988-08-16 | 1988-08-16 | Pharmaceutical devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1002201A5 true BE1002201A5 (fr) | 1990-10-09 |
Family
ID=26293670
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE8900312A BE1002201A5 (fr) | 1988-03-22 | 1989-03-22 | Compositions pharmaceutiques. |
| BE9000683A BE1004485A3 (fr) | 1988-03-22 | 1990-07-04 | Compositions pharmaceutiques. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE9000683A BE1004485A3 (fr) | 1988-03-22 | 1990-07-04 | Compositions pharmaceutiques. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0338670B1 (fr) |
| JP (1) | JP2927444B2 (fr) |
| AT (1) | AT409484B (fr) |
| BE (2) | BE1002201A5 (fr) |
| CA (1) | CA1329362C (fr) |
| CH (1) | CH679375A5 (fr) |
| DE (1) | DE68915203T2 (fr) |
| DK (1) | DK173673B1 (fr) |
| FR (1) | FR2628975B1 (fr) |
| GB (1) | GB2216794B (fr) |
| GR (1) | GR1000914B (fr) |
| IE (1) | IE64476B1 (fr) |
| LU (1) | LU87486A1 (fr) |
| PT (1) | PT90070B (fr) |
| SA (1) | SA90110073B1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596260B1 (en) * | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
| DE69637257T2 (de) | 1995-04-14 | 2008-06-12 | Smithkline Beecham Corp. | Verfahren zur Herstellung eines Dosierinhalators |
| SK284448B6 (sk) | 1995-04-14 | 2005-04-01 | Glaxo Wellcome Inc. | Merací dávkovací inhalátor |
| EA000889B1 (ru) * | 1995-04-14 | 2000-06-26 | Глаксо Веллкам Инк. | Дозирующий ингалятор дипропионата беклометазона |
| MX9707864A (es) | 1995-04-14 | 1997-11-29 | Glaxo Wellcome Inc | Inhalador de dosis medida por salmeterol. |
| US6315985B1 (en) | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
| GB2439402A (en) * | 2006-12-06 | 2007-12-27 | Bespak Plc | Methods of sterilisation of aerosol valve components |
| US8227027B2 (en) | 2007-12-07 | 2012-07-24 | Presspart Gmbh & Co. Kg | Method for applying a polymer coating to an internal surface of a container |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3024787A (en) * | 1957-03-20 | 1962-03-13 | Herbert M Birch | Means for administering pressurized medicaments, gases, combination thereof and liquids into body cavities |
| US3131834A (en) * | 1961-08-23 | 1964-05-05 | Meshberg Philip | Device and method for dispensing material under pressure of a propellent immiscible gs |
| US3985868A (en) * | 1973-06-27 | 1976-10-12 | American Cyanamid Company | Asthma treatment by inhalation of micronized N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate |
| EP0143577A1 (fr) * | 1983-11-18 | 1985-06-05 | FISONS plc | Soupape doseuse d'aérosol |
| EP0260067A2 (fr) * | 1986-09-09 | 1988-03-16 | Minnesota Mining And Manufacturing Company | Appareil pour la décharge d'une quantité prédéterminée d'un fluide sous pression |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE555319A (fr) * | 1956-03-21 | 1900-01-01 | ||
| NL262354A (fr) * | 1960-03-17 | |||
| US3304230A (en) * | 1963-02-18 | 1967-02-14 | Revlon | Liquid aerosol propellant solutions of fatty acid salts of physiologically active amines |
| GB1191412A (en) * | 1968-01-17 | 1970-05-13 | May & Baker Ltd | Aerosols and Compositions containing Prostaglandin Compounds |
| GB1399834A (en) * | 1971-05-12 | 1975-07-02 | Fisons Ltd | Pharmaceutical compositions |
| FI770215A7 (fr) * | 1976-01-30 | 1977-07-31 | Fisons Ltd | |
| DE2750090A1 (de) * | 1976-11-19 | 1978-06-01 | Sandoz Ag | Neue verabreichungsformen fuer organische verbindungen |
| US4086363A (en) * | 1977-03-16 | 1978-04-25 | Usv Pharmaceutical Corporation | Treatment of asthma |
| DE3015813C2 (de) * | 1980-04-24 | 1984-07-26 | Deutsche Calypsol GmbH, 4000 Düsseldorf | Druckpackung für kosmetische Emulsionen und Verfahren zur Abfüllung derartiger Druckpackungen |
| DE3682862D1 (de) * | 1985-04-16 | 1992-01-23 | Nastech Pharm Co | Aerosolmittel zur nasenverstaeubung von vitamin b 12. |
| JPS61273325A (ja) * | 1985-05-16 | 1986-12-03 | 日本ナシヨナル製罐株式会社 | 薄肉缶容器を用いた飲料の密封充填殺菌方法 |
| DE3700379A1 (de) * | 1987-01-08 | 1988-07-21 | Mann Gerhard Chem Pharm Fab | Konservierte augentropfen mit einem gehalt an cromoglicinsaeure |
-
1989
- 1989-03-09 GB GB8905408A patent/GB2216794B/en not_active Expired - Lifetime
- 1989-03-09 EP EP89302340A patent/EP0338670B1/fr not_active Expired - Lifetime
- 1989-03-09 DE DE68915203T patent/DE68915203T2/de not_active Expired - Lifetime
- 1989-03-20 CA CA000594241A patent/CA1329362C/fr not_active Expired - Lifetime
- 1989-03-20 JP JP1066498A patent/JP2927444B2/ja not_active Expired - Lifetime
- 1989-03-21 FR FR8903697A patent/FR2628975B1/fr not_active Expired - Lifetime
- 1989-03-21 DK DK198901391A patent/DK173673B1/da not_active IP Right Cessation
- 1989-03-21 IE IE88189A patent/IE64476B1/en not_active IP Right Cessation
- 1989-03-21 PT PT90070A patent/PT90070B/pt not_active IP Right Cessation
- 1989-03-21 LU LU87486A patent/LU87486A1/fr unknown
- 1989-03-21 GR GR890100177A patent/GR1000914B/el active IP Right Revival
- 1989-03-22 BE BE8900312A patent/BE1002201A5/fr not_active IP Right Cessation
- 1989-03-22 CH CH1062/89A patent/CH679375A5/fr not_active IP Right Cessation
- 1989-03-22 AT AT0066889A patent/AT409484B/de not_active IP Right Cessation
-
1990
- 1990-07-04 BE BE9000683A patent/BE1004485A3/fr active
- 1990-09-18 SA SA90110073A patent/SA90110073B1/ar unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3024787A (en) * | 1957-03-20 | 1962-03-13 | Herbert M Birch | Means for administering pressurized medicaments, gases, combination thereof and liquids into body cavities |
| US3131834A (en) * | 1961-08-23 | 1964-05-05 | Meshberg Philip | Device and method for dispensing material under pressure of a propellent immiscible gs |
| US3985868A (en) * | 1973-06-27 | 1976-10-12 | American Cyanamid Company | Asthma treatment by inhalation of micronized N,N-diethyl-4-methyl-1-piperazinecarboxamide pamoate |
| EP0143577A1 (fr) * | 1983-11-18 | 1985-06-05 | FISONS plc | Soupape doseuse d'aérosol |
| EP0260067A2 (fr) * | 1986-09-09 | 1988-03-16 | Minnesota Mining And Manufacturing Company | Appareil pour la décharge d'une quantité prédéterminée d'un fluide sous pression |
Also Published As
| Publication number | Publication date |
|---|---|
| DK173673B1 (da) | 2001-06-05 |
| DE68915203T2 (de) | 1994-09-22 |
| GR1000914B (el) | 1993-03-16 |
| PT90070A (pt) | 1989-11-10 |
| SA90110073B1 (ar) | 2004-08-14 |
| IE64476B1 (en) | 1995-08-09 |
| FR2628975B1 (fr) | 1995-03-17 |
| GB2216794B (en) | 1991-11-20 |
| JPH01277575A (ja) | 1989-11-08 |
| CH679375A5 (fr) | 1992-02-14 |
| DE68915203D1 (de) | 1994-06-16 |
| EP0338670B1 (fr) | 1994-05-11 |
| JP2927444B2 (ja) | 1999-07-28 |
| GB8905408D0 (en) | 1989-04-19 |
| ATA66889A (de) | 2002-01-15 |
| PT90070B (pt) | 1995-01-31 |
| GR890100177A (en) | 1990-01-19 |
| FR2628975A1 (fr) | 1989-09-29 |
| DK139189D0 (da) | 1989-03-21 |
| EP0338670A2 (fr) | 1989-10-25 |
| EP0338670A3 (fr) | 1991-01-09 |
| GB2216794A (en) | 1989-10-18 |
| DK139189A (da) | 1989-09-23 |
| BE1004485A3 (fr) | 1992-12-01 |
| AT409484B (de) | 2002-08-26 |
| IE890881L (en) | 1989-09-22 |
| LU87486A1 (fr) | 1990-10-02 |
| CA1329362C (fr) | 1994-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE20 | Patent expired |
Owner name: *FISONS P.L.C. Effective date: 20090322 |