BE775610Q - Derives amides d'acides halogeno et nitro benzoiques et leur preparation - Google Patents
Derives amides d'acides halogeno et nitro benzoiques et leur preparationInfo
- Publication number
- BE775610Q BE775610Q BE775610A BE775610A BE775610Q BE 775610 Q BE775610 Q BE 775610Q BE 775610 A BE775610 A BE 775610A BE 775610 A BE775610 A BE 775610A BE 775610 Q BE775610 Q BE 775610Q
- Authority
- BE
- Belgium
- Prior art keywords
- emi
- benzamidoalkylpiperazine
- derivs
- halogen
- acid chloride
- Prior art date
Links
- 229910052801 chlorine Inorganic materials 0.000 claims abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract description 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
<EMI ID=1.1> <EMI ID=2.1> <EMI ID=3.1> <EMI ID=4.1> <EMI ID=5.1> <EMI ID=6.1> <EMI ID=7.1> <EMI ID=8.1> <EMI ID=9.1> <EMI ID=10.1> <EMI ID=11.1> dans laquelle <EMI ID=12.1> <EMI ID=13.1> nant pas plus de trois atones de carbone ou un <EMI ID=14.1> <EMI ID=15.1> <EMI ID=16.1> <EMI ID=17.1> <EMI ID=18.1> <EMI ID=19.1> <EMI ID=20.1> <EMI ID=21.1> <EMI ID=22.1> <EMI ID=23.1> <EMI ID=24.1> <EMI ID=25.1> du sulfate de sodium., le chloroforme est ensuite évaporé sous - <EMI ID=26.1> <EMI ID=27.1> <EMI ID=28.1> <EMI ID=29.1> <EMI ID=30.1> <EMI ID=31.1> <EMI ID=32.1> Les exemples suivants., non limitatifs, illutrent ces préparations. <EMI ID=33.1> nutes, avec agitation, une solution de 15,8 g de chlorure d'aci- <EMI ID=34.1> <EMI ID=35.1> agite pendant 15 heures à la température ambiante , le produit <EMI ID=36.1> <EMI ID=37.1> <EMI ID=38.1> posé basique en solution dans l'Sthanol par un équivalent d'acide chlorhydrique en solution dans le même alcool. Son point de <EMI ID=39.1> Procédé b <EMI ID=40.1> <EMI ID=41.1> <EMI ID=42.1> <EMI ID=43.1> <EMI ID=44.1> <EMI ID=45.1> ,Les composes correspondants sont consignes dans le tableau suivent : <EMI ID=46.1> <EMI ID=47.1> <EMI ID=48.1> <EMI ID=49.1> <EMI ID=50.1> <EMI ID=51.1> <EMI ID=52.1> <EMI ID=53.1> <EMI ID=54.1> <EMI ID=55.1> <EMI ID=56.1> dans les mêmes conditions que sous a). Les. constantes du pro- duit obtenu sont les suivantes : <EMI ID=57.1> <EMI ID=58.1> <EMI ID=59.1> <EMI ID=60.1> <EMI ID=61.1> <EMI ID=62.1> <EMI ID=63.1> <EMI ID=64.1>
Claims (1)
- <EMI ID=65.1><EMI ID=66.1><EMI ID=67.1><EMI ID=68.1>chlore, et peut exister.. plusieurs fois sur le<EMI ID=69.1><EMI ID=70.1><EMI ID=71.1> <EMI ID=72.1> <EMI ID=73.1><EMI ID=74.1> <EMI ID=75.1><EMI ID=76.1><EMI ID=77.1><EMI ID=78.1><EMI ID=79.1>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR114791A FR1537901A (fr) | 1967-07-19 | 1967-07-19 | Dérivés amidés d'acides halogéno et nitro benzoïques et leur préparation |
| FR135764A FR93884E (fr) | 1967-07-19 | 1968-01-12 | Dérivés amidés d'acides halogéno et nitro benzoiques et leur préparation. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE775610Q true BE775610Q (fr) | 1972-03-16 |
Family
ID=32929144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE775610A BE775610Q (fr) | 1967-07-19 | 1971-11-19 | Derives amides d'acides halogeno et nitro benzoiques et leur preparation |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE775610Q (fr) |
| FR (2) | FR1537901A (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0104614A1 (fr) * | 1982-09-24 | 1984-04-04 | Chugai Seiyaku Kabushiki Kaisha | Dérivés du phénylpipérazine et leur procédé de préparation |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846430A (en) * | 1968-01-12 | 1974-11-05 | Bruneau & Cie Lab | 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine |
| IE911774A1 (en) * | 1990-06-11 | 1991-12-18 | Akzo Nv | Pyridinylpiperazine derivatives |
| SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| US5659033A (en) * | 1995-09-13 | 1997-08-19 | Neurogen Corporation | N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands |
-
1967
- 1967-07-19 FR FR114791A patent/FR1537901A/fr not_active Expired
-
1968
- 1968-01-12 FR FR135764A patent/FR93884E/fr not_active Expired
-
1971
- 1971-11-19 BE BE775610A patent/BE775610Q/fr active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0104614A1 (fr) * | 1982-09-24 | 1984-04-04 | Chugai Seiyaku Kabushiki Kaisha | Dérivés du phénylpipérazine et leur procédé de préparation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR93884E (fr) | 1969-05-30 |
| FR1537901A (fr) | 1968-08-30 |
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