BE792533A - Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation - Google Patents

Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation

Info

Publication number: BE792533A
Authority: BE; Belgium
Prior art keywords: pyrimidines; preparation process; new pyrazolo; pyrazolo; new
Prior art date: 1971-12-09

Application number

Other languages

English (en)

French (fr)

Inventor

Der K Robins

D E O'brien

T Novinson

R K Robins

R H Springer

Original Assignee

Int Chem & Nuclear Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-12-09

Publication date

1973-06-08

1972-04-20 Priority claimed from US245870A external-priority patent/US3925385A/en

1973-06-08 Publication of BE792533A publication Critical patent/BE792533A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BE792533D 1971-12-09 Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation BE792533A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US20653871A	1971-12-09	1971-12-09
US245870A US3925385A (en)	1972-04-20	1972-04-20	6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US27346572A	1972-07-20	1972-07-20
US29984072A	1972-10-24	1972-10-24

Publications (1)

Publication Number	Publication Date
BE792533A true BE792533A (fr)	1973-06-08

Family

ID=27498614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE792533D BE792533A (fr)	1971-12-09		Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation

Country Status (15)

Country	Link
JP (1)	JPS4864097A (2)
BE (1)	BE792533A (2)
BG (1)	BG22401A3 (2)
CH (1)	CH603652A5 (2)
DD (1)	DD104530A5 (2)
DE (1)	DE2257547A1 (2)
GB (1)	GB1412017A (2)
HU (1)	HU168530B (2)
IE (1)	IE37189B1 (2)
IL (1)	IL40895A (2)
LU (1)	LU66597A1 (2)
NL (1)	NL7216539A (2)
NO (1)	NO137012C (2)
RO (1)	RO62762A (2)
SE (1)	SE398751B (2)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281000A (en) *	1979-07-09	1981-07-28	American Cyanamid Company	Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
AU557300B2 (en) *	1982-03-16	1986-12-18	Farmitalia Carlo Erba S.P.A.	Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) *	1982-03-25	1983-11-30	Erba Farmitalia	Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
NZ208554A (en) *	1983-06-23	1987-06-30	American Cyanamid Co	(aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
DE3533050A1 (de) *	1985-09-17	1987-03-26	Basf Ag	7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide
CA1330079C (en) *	1988-10-13	1994-06-07	Michihiko Tsujitani	Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
AU651986B2 (en) *	1991-04-22	1994-08-11	Otsuka Pharmaceutical Factory, Inc.	Pyrazolo{1,5-a}pyrimidine derivative and anti-inflammatory containing the same
DE4333705C2 (de) *	1993-10-02	2003-10-30	Guenter Ege	Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
WO1995035298A1 (en) *	1994-06-21	1995-12-28	Otsuka Pharmaceutical Factory, Inc.	PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE
US5843951A (en) *	1995-09-28	1998-12-01	Otsuka Pharmaceutical Factory Inc.	Analgesic composition of pyrazolo(1,5-A) pyrimidines
FR2771631B1 (fr) *	1997-12-03	2001-02-02	Oreal	Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation
MXPA05002571A (es) *	2002-09-04	2005-09-08	Schering Corp	Pirazolopirimidinas como inhibidores de cinasa dependientes de ciclina.
US7161003B1 (en) *	2002-09-04	2007-01-09	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7119200B2 (en) *	2002-09-04	2006-10-10	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
TWI252851B (en) *	2003-07-24	2006-04-11	Ferrer Int	7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
ES2222813B1 (es) *	2003-07-24	2005-12-16	Ferrer Internacional, S.A.	N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
CA2902686C (en)	2013-04-25	2017-01-24	Beigene, Ltd.	Fused heterocyclic compounds as protein kinase inhibitors
CN112552401B (zh)	2013-09-13	2023-08-25	广州百济神州生物制药有限公司	抗pd1抗体及其作为治疗剂与诊断剂的用途
CN106604742B (zh)	2014-07-03	2019-01-11	百济神州有限公司	抗pd-l1抗体及其作为治疗剂及诊断剂的用途
US10864203B2 (en)	2016-07-05	2020-12-15	Beigene, Ltd.	Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer
WO2018033853A2 (en)	2016-08-16	2018-02-22	Beigene, Ltd.	Crystalline form of (s)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
WO2018033135A1 (en)	2016-08-19	2018-02-22	Beigene, Ltd.	Use of a combination comprising a btk inhibitor for treating cancers
US11555038B2 (en)	2017-01-25	2023-01-17	Beigene, Ltd.	Crystalline forms of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
EP3645569A4 (en)	2017-06-26	2021-03-24	BeiGene, Ltd.	IMMUNOTHERAPY FOR LIVER CELL CARCINOMA
US11377449B2 (en)	2017-08-12	2022-07-05	Beigene, Ltd.	BTK inhibitors with improved dual selectivity
WO2019108795A1 (en)	2017-11-29	2019-06-06	Beigene Switzerland Gmbh	Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
US20220249491A1 (en)	2019-06-10	2022-08-11	Beigene Switzerland Gmbh	Oral solid tablet comprising bruton's tyrosine kinase inhibitor and preparation method therefor
US11786531B1 (en)	2022-06-08	2023-10-17	Beigene Switzerland Gmbh	Methods of treating B-cell proliferative disorder

0
- BE BE792533D patent/BE792533A/xx unknown
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/xx unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 RO RO7200073093A patent/RO62762A/ro unknown
- 1972-12-09 BG BG022071A patent/BG22401A3/xx unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending

Also Published As

Publication number	Publication date
NL7216539A (2)	1973-06-13
IL40895A0 (en)	1973-01-30
NO137012B (no)	1977-09-05
CH603652A5 (2)	1978-08-31
IL40895A (en)	1976-12-31
GB1412017A (en)	1975-10-29
DE2257547A1 (de)	1973-06-14
IE37189L (en)	1973-06-09
BG22401A3 (bg)	1977-02-20
SE398751B (sv)	1978-01-16
DD104530A5 (2)	1974-03-12
HU168530B (2)	1976-05-28
IE37189B1 (en)	1977-05-25
RO62762A (fr)	1978-05-15
JPS4864097A (2)	1973-09-05
NO137012C (no)	1977-12-14
LU66597A1 (2)	1973-03-15

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