BE846194Q - Dosage par amplification enzymatique - Google Patents

Dosage par amplification enzymatique

Info

Publication number
BE846194Q
BE846194Q BE170633A BE170633A BE846194Q BE 846194 Q BE846194 Q BE 846194Q BE 170633 A BE170633 A BE 170633A BE 170633 A BE170633 A BE 170633A BE 846194 Q BE846194 Q BE 846194Q
Authority
BE
Belgium
Prior art keywords
dosage
enzymatic amplification
enzymatic
amplification
Prior art date
Application number
BE170633A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of BE846194Q publication Critical patent/BE846194Q/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BE170633A 1971-05-14 1976-09-14 Dosage par amplification enzymatique BE846194Q (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14360971A 1971-05-14 1971-05-14
US00304156A US3817837A (en) 1971-05-14 1972-11-06 Enzyme amplification assay

Publications (1)

Publication Number Publication Date
BE846194Q true BE846194Q (fr) 1976-12-31

Family

ID=26841233

Family Applications (1)

Application Number Title Priority Date Filing Date
BE170633A BE846194Q (fr) 1971-05-14 1976-09-14 Dosage par amplification enzymatique

Country Status (2)

Country Link
US (1) US3817837A (fr)
BE (1) BE846194Q (fr)

Families Citing this family (971)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US5677132A (en) * 1971-05-20 1997-10-14 Strahilevitz; Meir Immunological assay reagent package
US4375414A (en) * 1971-05-20 1983-03-01 Meir Strahilevitz Immunological methods for removing species from the blood circulatory system and devices therefor
DE2128670B2 (de) * 1971-06-09 1977-06-30 Merck Patent Gmbh, 6100 Darmstadt Immunologische isoenzym-bestimmungsmethode
NL171930C (nl) * 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3878187A (en) * 1972-09-11 1975-04-15 Syva Co Polypeptide derivatives of amphetamine and analogs for immunoassays
DE2258822A1 (de) * 1972-12-01 1974-06-06 Merck Patent Gmbh Verfahren und mittel zur analyse von isoenzymmustern
US3959078A (en) * 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
US4255329A (en) * 1973-10-02 1981-03-10 Syva Company Double receptor fluorescent immunoassay
GB1511571A (en) * 1974-06-28 1978-05-24 Syva Co Lactam compounds and conjugates
CA1028643A (fr) * 1975-02-20 1978-03-28 Judith I. Blakemore Dosage immunologique de la polylodothyronine
US4171244A (en) * 1975-02-20 1979-10-16 Syva Company Enzyme-bound-polyidothyronine
US4043872A (en) * 1975-02-20 1977-08-23 Syva Company Polyiodothyronine immunoassay
US4025501A (en) * 1975-03-20 1977-05-24 Syva Company Polypeptide propoxyphene derivatives for immunoassay reagents
US4230797A (en) * 1975-04-28 1980-10-28 Miles Laboratories, Inc. Heterogenous specific binding assay employing a coenzyme as label
US4629688A (en) * 1975-04-28 1986-12-16 Miles Laboratories, Inc. Homogeneous specific binding assay method
IN142734B (fr) * 1975-04-28 1977-08-20 Miles Lab
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
US4642285A (en) * 1975-09-29 1987-02-10 Diamedix Corporation Sandwich EIA for antigen
US4474878A (en) * 1975-09-29 1984-10-02 Cordis Laboratories, Inc. Sandwich EIA for antigen associated with hepatitis
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
US4069105A (en) * 1977-03-03 1978-01-17 Syva Company Lidocaine antigens and antibodies
IT1153999B (it) * 1977-03-15 1987-01-21 Snam Progetti Composizione atta alla determinazione della triiodotironina e metodo diagnostico impiegante la stessa
US4156081A (en) * 1977-04-15 1979-05-22 Syva Company Theophylline antigens and antibodies
IT1105734B (it) * 1977-07-14 1985-11-04 Syva Co Prova di legame di competizione di antienzima omogeneo
US4233401A (en) * 1977-07-14 1980-11-11 Syva Company Antienzyme homogeneous competitive binding assay
US4168207A (en) * 1977-08-03 1979-09-18 Syva Company TBG assay
US4239852A (en) * 1978-06-12 1980-12-16 Penicillin Assays, Inc. Antibiotic detection method
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4791055A (en) * 1978-04-10 1988-12-13 Miles Inc. Homogenous specific binding assay reagent system and labeled conjugates
US4318980A (en) * 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
US4492751A (en) * 1978-04-10 1985-01-08 Miles Laboratories, Inc. Heterogenous specific binding assay employing an enzyme substrate as label
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
US4235969A (en) * 1978-05-08 1980-11-25 Syva Company Procainamide antigen conjugates and antibodies
US4244939A (en) * 1978-06-12 1981-01-13 Baxter Travenol Laboratories, Inc. Barbituric acid tracers and their preparation
US4234681A (en) * 1978-07-21 1980-11-18 The Regents Of The University Of California Immobolized light emitting systems
US4241177A (en) * 1978-08-28 1980-12-23 Syva Company Propanolol antigen conjugates and antibodies
US4239745A (en) * 1978-11-22 1980-12-16 Penicillin Assays, Inc. Antibiotic detection method
WO1980002800A1 (fr) * 1979-06-21 1980-12-24 G Oster Indicateur specifique d'ovulation imminente
US6414152B1 (en) 1981-12-11 2002-07-02 University Of Wales College Of Medicine Of Heath Park Luminescent labelling material and procedures
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
WO1981001414A1 (fr) * 1979-11-19 1981-05-28 Charles Hospital Dev Procede ameliore d'analyse immunologique d'enzymes non homogenes
US4372745A (en) * 1979-12-19 1983-02-08 Electro-Nucleonics, Inc. Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer
US4347312A (en) * 1980-03-20 1982-08-31 Research Triangle Institute Detection of antibiotics in milk
JPS5714748A (en) * 1980-07-01 1982-01-26 Dainippon Pharmaceut Co Ltd Kit for quantitative determination of valproic acid and its method for quantitative determination
DE3068426D1 (en) * 1980-07-11 1984-08-09 Syva Co Valproate derivatives and their conjugates to antigenic materials, antibodies thereto and method for the determination of valproate in physiological fluids
CA1164340A (fr) * 1980-09-02 1984-03-27 Alex A. Monte Dosage immunologique
US4378428A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
US4378458A (en) 1981-03-30 1983-03-29 Baker Instruments Corporation Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity
US4785080A (en) * 1981-03-30 1988-11-15 Baker Instruments Corporation Labeled analytes
US4489156A (en) * 1981-04-23 1984-12-18 Syva Company Chloramphenicol derivatives
US4608252A (en) * 1981-04-23 1986-08-26 Syntex (U.S.A.) Inc. Chloramphenicol derivatives antigens and antibodies
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
JPS5818167A (ja) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
US4489157A (en) * 1981-09-28 1984-12-18 Syva Company Chloramphenicol derivatives
GB2112779B (en) * 1981-12-11 1986-10-15 Welsh Nat School Med Aryl acridinium esters as luminescent labelling materials
US5103021A (en) * 1982-04-02 1992-04-07 Syntex (U.S.A.) Inc. Acetaminophen analogs, antigens, and antibodies
US4446233A (en) * 1982-05-05 1984-05-01 E. I. Du Pont De Nemours And Company Homogeneous immunoassay using covalent hybrid antibodies
EP0095286B1 (fr) * 1982-05-26 1985-12-18 Boots-Celltech Diagnostics Limited Essai immunologique
US4472301A (en) * 1982-05-27 1984-09-18 Miles Laboratories, Inc. Propranolol immunogen and antibodies
US4606855A (en) * 1982-07-26 1986-08-19 Mex Research Associates C/O Leon Reimer Monoclonal antibody to digoxin
US4477576A (en) * 1982-07-26 1984-10-16 Mex Research Associates Antigen assay method and kit
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
US4544629A (en) * 1982-11-19 1985-10-01 Minnesota Mining And Manufacturing Company Receptor-based histamine assay
AU559576B2 (en) * 1983-01-31 1987-03-12 Boots-Celltech Diagnostics Limited Immunoassay
US4614712A (en) * 1983-02-25 1986-09-30 The Upjohn Company Immunoassays with luciferase labeled ligands or receptors
US5089388A (en) * 1983-04-19 1992-02-18 Syntex (U.S.A.) Inc. Antibodies for salicylate and their preparation
US4496479A (en) * 1983-05-18 1985-01-29 Syntex (U.S.A.) Company Chloramphenicol derivatives, antigens and antibodies
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
US4575485A (en) * 1983-08-29 1986-03-11 Syntex (U.S.A.) Inc. Ultrasonic enhanced immuno-reactions
US4560648A (en) * 1983-09-23 1985-12-24 Syntex (U.S.A.) Inc. Homogeneous enzyme immunoassay for ferritin
EP0159355A1 (fr) * 1983-10-17 1985-10-30 Inomedix, Incorporated Dispositif d'analyse quantitative rapide d'un fluide
US4719176A (en) * 1983-10-31 1988-01-12 Klotz Irving M Enzyme-free diagnostic binding reagents
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
US4654311A (en) * 1984-06-15 1987-03-31 Syntex (U.S.A.) Inc. Serum pretreatment for digoxin assay
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
DE3587549T2 (de) * 1984-10-29 1994-02-17 Microgenics Corp Ergänzungstestverfahren von proteine bindenden enzymen.
IT1178788B (it) * 1984-12-21 1987-09-16 Sclavo Spa Metodo immunoenzimatico per la determinazione di analiti e composizione adatti allo scopo
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
ATE72831T1 (de) * 1985-05-31 1992-03-15 Syntex Inc Konjugate von glucose-6-phosphat-dehydrogenase, ihre herstellung und verwendung.
US4689397A (en) * 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4830786A (en) * 1986-02-27 1989-05-16 Syntex (U.S.A.) Inc. Squaraine dyes
US5039818A (en) * 1986-02-27 1991-08-13 Syntex (U.S.A.) Inc. Squaraine dye
US4721704A (en) * 1986-05-09 1988-01-26 Peninsula Laboratories, Inc. Potent synthetic atrial peptide analogs
US4888276A (en) * 1986-06-26 1989-12-19 Minnesota Mining And Manufacturing Company Method and composition for the diagnosis of Lyme disease
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
US4868132A (en) * 1987-02-03 1989-09-19 Abbott Laboratories Fluorescence polarization immunoassay for amphetamine/methamphetamine
US5241012A (en) 1987-05-19 1993-08-31 Applied Immune Sciences, Inc. Activated and conjugated polystyrene substrate
US6326136B1 (en) 1988-04-01 2001-12-04 Digene Corporation Macromolecular conjugate made using unsaturated aldehydes
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5057430A (en) * 1988-09-15 1991-10-15 Biotronic Systems Corporation Biochemical sensor responsive to bubbles
US5135863A (en) * 1988-12-23 1992-08-04 Syntex (U.S.A.) Inc. Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine
US5358690A (en) * 1989-01-10 1994-10-25 Lamina, Ltd. Environmental sample collection and membrane testing device
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5073629A (en) * 1989-01-23 1991-12-17 Abbott Laboratories Methadone fluorescence polarization immunoassay
US5639624A (en) * 1989-03-14 1997-06-17 Board Of Regents Of The University Of Nebraska Monoclonal antibodies specific for metallic cations and method therefor
US5101015A (en) * 1989-04-10 1992-03-31 Abbott Laboratories Reagents for an amphetamine-class fluorescence polarization immunoassay
US5248791A (en) * 1989-04-10 1993-09-28 Abbott Laboratories Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay
CA1335707C (fr) * 1989-08-15 1995-05-30 Pyare Khanna Test de depistage de l'usage de drogues
US5358931A (en) * 1990-01-17 1994-10-25 The Regents Of The University Of California Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5532138A (en) * 1990-04-26 1996-07-02 Behringwerke Ag Method and kits for determining peroxidatively active catalysts
US5143852A (en) * 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
ATE185424T1 (de) * 1991-07-29 1999-10-15 Serex Inc Differentielle bindungsaffinitäten und darauf beruhende dissoziationstestverfahren
US5279937A (en) * 1992-04-30 1994-01-18 Detechnology Canada Use of macroglobulins to improve the signal-to-background ratio in affinity binding assays
US5273885A (en) * 1992-07-31 1993-12-28 Syntex (U.S.A.) Inc. Conjugates of monophenyl thyroid analogs useful in assays
US5518890A (en) * 1992-11-20 1996-05-21 Mccormick & Company, Inc. Method and apparatus for the quantitation and separation of contaminants from particulate materials
WO1994020636A1 (fr) * 1993-03-09 1994-09-15 Abbott Laboratories Enzymes produites par genie genetique et conjugues desdites enzymes pour des analyses diagnostiques
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US6953573B1 (en) * 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5395752A (en) * 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
US6455288B1 (en) * 1993-04-08 2002-09-24 Dade Behring Marburg Gmbh Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US20040259113A1 (en) * 1993-07-22 2004-12-23 Mayo Foundation For Medical Education And Research, Hybritech Incorporated Method for detection of metastatic prostate cancer
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5516647A (en) * 1993-11-05 1996-05-14 Abbott Laboratories Compounds useful as alkaline phosphatase inhibitors and therapeutic agents
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5710009A (en) * 1994-02-17 1998-01-20 Serex, Inc. Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon
US5856083A (en) * 1994-05-06 1999-01-05 Pharmacopeia, Inc. Lawn assay for compounds that affect enzyme activity or bind to target molecules
WO1995030758A1 (fr) * 1994-05-10 1995-11-16 Mayo Foundation For Medical Education And Research Polypeptide hk2 recombine
EP0705903B2 (fr) 1994-08-12 2009-08-12 The University of Utah Research Foundation Mutations du gène lié à 17q conférant une susceptibilité au cancer du sein et des ovaires
DK0699754T3 (da) 1994-08-12 2001-02-26 Myriad Genetics Inc Fremgangsmåde til diagnosticering af prædisposition for bryst- og ovariecancer
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US5633149A (en) 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
CA2245835A1 (fr) 1995-06-14 1997-01-03 The Regents Of The University Of California Nouveaux anticorps humains a forte affinite diriges contre des antigenes tumoraux
US6346510B1 (en) 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
IL124620A0 (en) 1995-12-18 1998-12-06 Myriad Genetics Inc Chromosome 13-linked breast cancer susceptibility gene
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
EP0880598A4 (fr) 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US5808074A (en) * 1996-02-02 1998-09-15 Georgetown University Benzoylecgonine conjugate diagnostic reagents
US6924094B1 (en) 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
EP0937159A4 (fr) 1996-02-08 2004-10-20 Affymetrix Inc Speciation de micro-organismes a partir de microplaquettes et caracterisation des phenotypes de ceux-ci
EP1728875A3 (fr) 1996-02-08 2007-05-09 Affymetrix, Inc. Spéciation de micro-organismes à partir de micro plaquettes et caractérisation des phénotypes de ceux-ci
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
EP0888124A4 (fr) * 1996-03-22 2001-04-11 Univ Georgia Res Found Compositions immunogenes comprenant des peptides porphyromonas gingivalis et procedes
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
DK0912738T3 (da) 1996-05-22 2008-11-17 Viventia Biotech Inc Antigen-bindende-fragmenter der specifikt detekterer cancerceller, nukleotider der koder fragmenterne og anvendelse deraf til profylakse og detektion af cancere
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
WO1998001533A1 (fr) 1996-07-08 1998-01-15 Burstein Laboratories, Inc. Procede et dispositif a element de signal clivable
EP0880705B1 (fr) 1996-07-18 2003-06-18 Dade Behring Marburg GmbH Reactif pour le dosage de l'acide mycophenolique
EP0880704B1 (fr) * 1996-07-18 2003-09-24 Dade Behring Marburg GmbH Reactif pour le dosage de l'acide mycophenolique
ES2308787T3 (es) 1996-08-16 2008-12-01 Schering Corporation Antigenos de superficie de celular de mamiferos; reactivos relacionados.
CA2266325C (fr) * 1996-09-24 2012-07-17 Lxr Biotechnology, Inc. Famille de genes codant les peptides lies a l'apoptose, peptides ainsi codes et leurs procedes d'utilisation
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6610839B1 (en) * 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
EP0932686A2 (fr) 1996-10-01 1999-08-04 Geron Corporation Transcriptase inverse de la telomerase
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US7585622B1 (en) 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6475789B1 (en) 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US6093809A (en) 1996-10-01 2000-07-25 University Technology Corporation Telomerase
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
EP1803816A3 (fr) 1996-12-13 2007-09-26 Schering Corporation Antigènes de surface de céllules mammaliennes et réactifs qui y sont liés
JP4649602B2 (ja) 1997-02-07 2011-03-16 アメリカ合衆国 活性依存性向神経第▲ｉｉｉ▼因子（ａｄｎｆ▲ｉｉｉ▼）
US6127338A (en) 1997-04-01 2000-10-03 Calyx Therapeutics, Inc. Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
ATE458053T1 (de) 1997-05-07 2010-03-15 Schering Corp Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren
DE69831229T2 (de) 1997-05-14 2006-04-13 Biosite Diagnostics Inc., San Diego Schnelle bestimmung des verhältnisses von biologischen molekülen
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
AU8259798A (en) 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
AR014891A1 (es) 1997-07-09 2001-04-11 Schering Corp Genes aislados de proteinas de membranas de mamiferos; reactivos relacionados
US6228638B1 (en) 1997-07-11 2001-05-08 University Of North Texas, Health Science Center At Fort Worth Escherichia coli CSRB gene and RNA encoded thereby
US20030157642A1 (en) 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6521421B1 (en) * 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
PE20000183A1 (es) 1997-07-25 2000-03-11 Schering Corp Citoquinas de mamiferos y reactivos relacionados
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
ES2274574T3 (es) 1997-08-01 2007-05-16 Schering Corporation Proteinas de membrana celular de mamifero; reactivos relacionados.
US5929049A (en) 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
US7252950B1 (en) 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US6521440B1 (en) 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
US6599731B1 (en) * 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) * 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6465186B1 (en) 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US6060260A (en) * 1998-02-27 2000-05-09 Dade Behring Inc. Methods for reducing adsorption in an assay
BR9908422A (pt) 1998-03-04 2000-10-31 Genencor Int Pululanase modificada, ácido nucleico, vetor de expressão, microorganismo hospedeiro, processo para a produção de uma pululanase modificada em uma célula hospedeira, composição enzimática, processo para sacarificação de amido, e, b. licheniformis
WO1999047934A2 (fr) 1998-03-20 1999-09-23 The Curators Of The University Of Missouri Compositions et methodes pour un diagnostic precoce de la grossesse
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
ATE328278T1 (de) 1998-03-30 2006-06-15 Orasure Technologies Inc Sammelapparat für einschrittigen test von mundflüssigkeiten
AU3217599A (en) * 1998-03-31 1999-10-18 Genzyme Corporation Methods for the diagnosis and treatment of lung cancer
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
EP1071943A4 (fr) 1998-04-14 2005-08-10 Univ California Dosages de detection d'inhibiteurs de depolymerisation de microtubules
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
EP1086123A1 (fr) * 1998-06-09 2001-03-28 Immco Diagnostics Technique elisa pour phase en solution
US6171802B1 (en) * 1998-06-10 2001-01-09 Kent State University Detection and amplification of ligands
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
CA2338401A1 (fr) * 1998-07-21 2000-02-03 Burstein Laboratories, Inc Dispositifs de dosage utilisant des disques optiques et methodes correspondantes
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
WO2000017362A1 (fr) 1998-09-21 2000-03-30 Schering Corporation Interleukine humaine b50, ses utilisations therapeutiques
EP0997476A3 (fr) 1998-09-25 2000-07-19 Schering-Plough Anticorps contre un antigène de cellules Langerhans mammifères et leurs utilisations
DE60043051D1 (de) 1999-01-11 2009-11-12 Schering Corp Dafür kodierende polynukleotide. verwendungen
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
US7025961B1 (en) 1999-03-04 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Anti-plasmodium composition and methods of use
EP1942114A3 (fr) 1999-03-11 2008-08-27 Schering Corporation "Cytokines de mammifères ; réactifs et procédés associés"
NZ515382A (en) 1999-05-13 2004-03-26 Medical Res Council OX2 receptor homologs
DK2385124T3 (da) 1999-05-14 2013-11-18 Arbor Vita Corp Peptider, eller peptid-analoger, til modulering af bindingen af et PDZ protein og et PL protein
SI1181366T2 (sl) 1999-06-01 2013-10-30 Merck Sharp & Dohme Corp. Sesalski receptorski proteini; sorodni reagenti in postopki
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
EP1196398A4 (fr) 1999-07-06 2002-11-06 Surromed Inc Colorants fluorescents pontes, leur preparation et leur utilisation dans des dosages
US6531130B1 (en) 1999-07-06 2003-03-11 The Board Of Trustees Of The Leland Stanford University Treatment of demyelinating autoimmune disease with ordered peptides
CN1365391A (zh) 1999-07-30 2002-08-21 先灵公司 哺乳动物细胞因子以及相关试剂
US7078495B1 (en) 1999-08-03 2006-07-18 Dade Behring Inc. Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus
EP1905832A3 (fr) 1999-09-09 2009-09-09 Schering Corporation Interleukin-12 P40 et interleukin B30 de mammifères, anticorps, utilisation dans des compositions pharmaceutiques
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
WO2001038352A2 (fr) 1999-11-24 2001-05-31 Schering Corporation Procedes d'inhibition de metastases
JP4972264B2 (ja) 1999-12-06 2012-07-11 ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ 高親和性ｔｃｒタンパク質および方法
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (fr) 2000-01-12 2003-01-02 Light Sciences Corporation Nouveau traitement pour maladie des yeux
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
AU3988401A (en) * 2000-02-25 2001-09-03 Ludwig Inst Cancer Res Materials and methods involving hybrid vascular endothelial growth factor dnas and proteins
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
EP2389943A1 (fr) 2000-04-18 2011-11-30 Schering Corporation Utilisation d'antagonistes IL-174 pour traiter les liées aux Th2
WO2001084157A2 (fr) 2000-05-04 2001-11-08 Dade Behring Marburg Gmbh Compositions servant a la detection d'analytes multiples
CA2408571C (fr) 2000-05-10 2014-04-29 Schering Corporation Proteines de recepteur de mammifere, reactifs lies et techniques
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
NZ522327A (en) 2000-05-25 2004-09-24 Schering Corp Mammalian DNAX Toll-like receptor protein, DTLR 10, antibodies and medicaments made therefrom and use in treating immunological disorders
WO2005000087A2 (fr) * 2003-06-03 2005-01-06 Chiron Corporation Produits genetiques exprimes de facon differentielle dans des cellules cancereuses du colon et leurs methodes d'utilisation ii
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
GR1004119B (en) * 2000-07-26 2003-01-23 Αυτοματοι Αναλυτες Και Διαγνωστικα Αντιδραστηρια Medicon Hellas Α.Ε. DEVELOPMENT OF A NEW HOMOGENEOUS IMMUNOENZYMIC METHOD FOR THE PRODUCTION OF A CLINICAL LABORATORY TEST SYSTEM (kit) FOR THE QUANTIFICATION OF THYROXINE AND TRIIODOTHYRONINE IN HUMAN SERUM, UTILIZINGPOLYIODOTHYRONINE CONJUGATED WITH GLYCOGEN PHOSPHO....
US20020127241A1 (en) * 2000-08-07 2002-09-12 Narum David L. Anti-plasmodium compositions and methods of use
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
EP1315512A4 (fr) 2000-09-08 2005-11-09 Univ Texas Ciblage ad noviral et manipulation de la r ponse du syst me immunitaire au moyen de peptides ciblants
JP2004509617A (ja) 2000-09-08 2004-04-02 シェーリング　コーポレイション 哺乳動物遺伝子；関連試薬および方法
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
WO2002022667A2 (fr) * 2000-09-18 2002-03-21 Genencor International, Inc. Translocation des arginines couplees dans bacillus
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
US20020172980A1 (en) * 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
US20040248093A1 (en) * 2000-11-27 2004-12-09 Coombs James Howard Magneto-optical bio-discs and systems including related methods
US20030003464A1 (en) * 2000-11-27 2003-01-02 Phan Brigitte C. Dual bead assays including optical biodiscs and methods relating thereto
AU2002252773A1 (en) * 2000-11-29 2002-06-11 Lynkeus Boitech Gmbh Retina-specific human proteins c70rf9, c120rf7, mpp4 and f379
AU2002220275A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
US7087395B1 (en) 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
AU2002258502A1 (en) * 2001-03-12 2002-09-24 Affymetrix, Inc. Nucleic acid labeling compounds
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
AU2002254524A1 (en) * 2001-04-06 2002-10-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health A Use of semenogelin in the diagnosis, prognosis and treatment of cancer
ES2284897T3 (es) 2001-05-18 2007-11-16 Danisco A/S Procedimiento para la preparacion de una masa con una enzima.
DE60229846D1 (de) 2001-05-22 2008-12-24 Merck & Co Inc Beta-secretase-substrat und seine verwendung
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
WO2003012030A2 (fr) * 2001-08-01 2003-02-13 University Of Utah, Technology Transfer Office Inhibiteurs et activateurs selectifs d'isoformes de phosphodiesterases nucleotidiques cycliques pde3
US6833441B2 (en) * 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US20060073530A1 (en) * 2001-08-15 2006-04-06 Olaf Schneewind Methods and compositions involving sortase B
US8118991B2 (en) * 2001-09-04 2012-02-21 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
US7166208B2 (en) * 2004-03-03 2007-01-23 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
US7718387B2 (en) 2001-09-20 2010-05-18 Board Of Regents, The University Of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays
US7393696B2 (en) * 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
CA2462883A1 (fr) 2001-10-12 2003-04-17 Schering Corporation Utilisation d'anticorps bispecifiques pour reguler des reponses immunitaires
US20030170678A1 (en) * 2001-10-25 2003-09-11 Neurogenetics, Inc. Genetic markers for Alzheimer's disease and methods using the same
US20030224380A1 (en) * 2001-10-25 2003-12-04 The General Hospital Corporation Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases
AU2002364945A1 (en) * 2001-10-25 2003-07-09 Neurogenetics, Inc. Genes and polymorphisms on chromosome 10 associated with alzheimer's disease and other neurodegenerative diseases
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
EP1468288A4 (fr) 2001-11-20 2006-03-15 Univ Missouri Compositions et methodes pour le diagnostic precoce precis de la grossesse
US6696254B2 (en) 2001-11-21 2004-02-24 Kimberly-Clark Worldwide, Inc. Detection and identification of enteric bacteria
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US9575070B2 (en) * 2001-12-04 2017-02-21 Wayne State University Neoepitope detection of disease using protein arrays
DK2311869T3 (da) 2002-02-01 2013-03-18 Merck Sharp & Dohme Anvendelse af pattedyrcytokinrelaterede reagenser
EP2508596B1 (fr) 2002-02-21 2015-08-12 Institute Of Virology Anticorps monoclonaux spécifiques au MN/CA IX générés à partir de souris déficientes en MN/CA IX et procédés d'utilisation
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
AU2003225589A1 (en) 2002-02-22 2003-09-09 The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Brother of the regulator of imprinted sites (boris)
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
EP1501939B1 (fr) * 2002-04-16 2009-07-22 The Regents of The University of California Methodes de pronostic d'un hypernephrome et selection de traitement a l'aide d'une anhydrase ix carbonique
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
CA2391438A1 (fr) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Reactifs et methodes diagnostiques a base de psp94
EP1546716A4 (fr) * 2002-05-02 2007-04-11 Aspenbio Inc Detection de la gravidite
AU2003228809A1 (en) 2002-05-03 2003-11-17 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
NZ537328A (en) * 2002-05-31 2008-04-30 Genetic Technologies Ltd Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
US7560239B2 (en) * 2002-06-04 2009-07-14 Lin-Zhi International Inc. Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes
EP1517684B1 (fr) 2002-06-27 2009-07-22 Health Research, Inc. Photosensibilisants fluores associes a des chlores et des bacteriochlores pour la therapie photodynamique
WO2004005289A2 (fr) * 2002-07-02 2004-01-15 Health Research, Inc. Synthese efficace de pyropheophorbide a et ses derives
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
EP2357009A1 (fr) 2002-07-15 2011-08-17 Board of Regents, The University of Texas System Conjugés comprenant un peptide de duramycine se fixant à des phospholipides et des aminophospholipides anioniques et leur utilisation dans le traitement d'infections virales
US6916474B2 (en) 2002-07-15 2005-07-12 Board Of Regents, The University Of Texas System Antibodies with increased affinities for anthrax antigens
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
PT1534736E (pt) 2002-08-10 2010-09-07 Univ Yale Antagonistas do receptor nogo
EP2204654B1 (fr) * 2002-08-13 2012-12-12 N-Dia, Inc. Utilisation des dispositifs et procédés pour détecter du liquide amniotique dans les sécrétions vaginales
BR0314155A (pt) 2002-09-09 2005-07-05 Arbor Vita Corp Métodos para diagnosticar câncer cervical
EP1556682B8 (fr) * 2002-10-21 2010-02-17 DiscoveRx Corporation Biodosage de ip3 par liason de proteine
EP1556040A1 (fr) 2002-10-24 2005-07-27 Sterix Limited Inhibiteurs de 11-beta-hydroxy steroide dehydrogenase de type 1 et de type 2
JP5271475B2 (ja) * 2002-11-26 2013-08-21 ザ ユニヴァーシティー オヴ シカゴ 微生物媒介上皮疾患の予防及び治療のための材料並びに方法
US8323897B2 (en) 2002-12-04 2012-12-04 Applied Biosystems, Llc Multiplex amplification of polynucleotides
US20040229245A1 (en) * 2003-01-06 2004-11-18 Anton Bittner Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology
US20050196766A1 (en) * 2003-12-24 2005-09-08 Soe Jorn B. Proteins
US7955814B2 (en) * 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007653A (es) * 2003-01-17 2005-09-30 Danisco Metodo.
ES2661213T3 (es) 2003-01-17 2018-03-28 Dupont Nutrition Biosciences Aps Método para la producción in situ de un emulsionante en un producto alimenticio
CA2518677A1 (fr) * 2003-03-03 2004-12-09 Nagaoka & Co., Ltd. Procedes et appareil utilises pour la detection et la quantification de divers types de cellules et utilisation d'un bio-disque optique pour leur mise en oeuvre
WO2004078999A1 (fr) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification d'adn foetal et de marqueurs de cellule foetale dans du plasma ou du serum maternel
EP1603511B1 (fr) 2003-03-07 2011-01-26 New England Medical Center Hospitals, Inc. Traitement de maladies a depot d'iga1
US20070141570A1 (en) * 2003-03-07 2007-06-21 Sequenom, Inc. Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods
US20050003147A1 (en) * 2003-03-24 2005-01-06 Anderson-Tully Engineered Wood Llc Laminated board and methods of producing the same
ES2433440T3 (es) 2003-04-04 2013-12-11 Yeda Research And Development Co. Ltd. Anticuerpos contra MMP2 o MMP9 y composiciones farmacéuticas que contienen los mismos útiles para inhibir la actividad de dichas metaloproteínas
EP1615654A2 (fr) * 2003-04-16 2006-01-18 Yale University Traitement d'etats impliquant des plaques amyloides
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
CA2542984A1 (fr) * 2003-07-07 2005-01-27 David H. Wagner Methodes de prediction du developpement de maladies auto-immunes et traitement associe
ATE536889T1 (de) 2003-07-08 2011-12-15 Accumetrics Inc Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
EP1668111A4 (fr) 2003-08-08 2008-07-02 Genenews Inc Biomarqueurs d'osteoarthrite et leurs utilisations
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
US20080050313A1 (en) 2003-08-14 2008-02-28 Exelixis, Inc. Sulfs as Modifiers of the Beta-Catenin Pathway and Methods of Use
EP1668015B1 (fr) * 2003-09-04 2013-08-21 Technion Research And Development Foundation, Ltd. Ensemble de cucurbituril et ses utilisations
EP2287616A1 (fr) 2003-09-15 2011-02-23 Oklahoma Medical Research Foundation Procédé d'utilisation de dosages de cytokine pour diagnostiquer, traiter et évaluer le lupus érythémateux systémique
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
ATE474598T1 (de) 2003-11-04 2010-08-15 Novartis Vaccines & Diagnostic Verwendung von antagonisten-anti-cd40-antikörpern zur behandlung von chronisch lymphozytischer leukämie
CA2544951A1 (fr) 2003-11-04 2005-05-19 Chiron Corporation Utilisation d'anticorps monoclonaux antagonistes anti-cd40 pour le traitement de myelome multiple
EP1680141B8 (fr) 2003-11-04 2011-01-12 Novartis Vaccines and Diagnostics, Inc. Procedes therapeutiques de tumeurs solides exprimant l'antigene de surface cellulaire cd40
PT1694360E (pt) 2003-11-04 2010-12-13 Novartis Vaccines & Diagnostic Utilização de anticorpos monoclonais antagonistas anti-cd40 para o tratamento de doenças auto-imunes e inflamatórias e da rejeição ao transplante de orgãos
PE20050925A1 (es) 2003-11-10 2005-11-29 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
JP3615752B1 (ja) 2003-11-18 2005-02-02 淳 高橋 細径樹脂捩じりブラシ
US7022492B2 (en) 2003-12-15 2006-04-04 Dade Behring Inc. Ecstasy haptens and immunogens
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
JP5030594B2 (ja) 2003-12-23 2012-09-19 アルボー ビータ コーポレーション Ｈｐｖの発癌性株に対する抗体およびそれらの使用方法
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
DK2119771T3 (en) 2003-12-24 2018-12-10 Dupont Nutrition Biosci Aps PROTEINS
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
CA2555208A1 (fr) * 2004-02-18 2005-09-01 Merck & Co., Inc. Molecules d'acide nucleique codant de nouvelles proteines murines a canal de calcium active faible tension, 1h alpha specialise, proteines codees et procedes d'utilisation de celles-ci
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
WO2005085475A1 (fr) 2004-03-01 2005-09-15 Applera Corporation Techniques, compositions et kits d'amplification de polynucleotide
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
EP1744767A4 (fr) * 2004-04-20 2008-08-13 Univ Chicago Systeme d'administration therapeutique comprenant un compose de type peg de poids moleculaire eleve
US8586294B2 (en) 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
AU2005250370B2 (en) 2004-05-28 2010-04-01 Agensys, Inc. Antibodies and related molecules that bind to PSCA proteins
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
JP4796059B2 (ja) * 2004-06-30 2011-10-19 ディスカヴァーエックス コーポレイション 細胞内修飾の分析
CN102533440B (zh) * 2004-07-16 2017-09-19 杜邦营养生物科学有限公司 用酶使油脱胶的方法
CA2579790A1 (fr) * 2004-07-30 2006-02-09 Mount Sinai School Of Medicine Of New York University Inhibiteurs de npc1l1 et npc1l1 et procedes d'utilisation associes
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
EP2386640B1 (fr) 2004-08-26 2015-01-28 EnGeneIC Molecular Delivery Pty Ltd Transfert d'acides nucléiques fonctionnels aux cellules de mammifères au moyen de mini-cellules intactes dérivées de bactéries
US20060046273A1 (en) * 2004-08-27 2006-03-02 Lin-Zhi International Inc. Homogeneous enzyme immunoassay for oral fluid
FI20050753A7 (fi) 2004-09-03 2006-03-04 Licentia Oy Uudet peptidit
EP1802775B1 (fr) 2004-09-14 2010-05-26 The Regents of the University of Colorado Procédé de traitement faisant intervenir du bucindolol fondé sur le ciblage génétique
AU2005287090A1 (en) 2004-09-18 2006-03-30 Department Of Veterans Affairs Therapeutic agents targeting the NCca-ATP channel and methods of use thereof
JP5307397B2 (ja) 2004-09-18 2013-10-02 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする治療剤およびその使用方法
EA011879B1 (ru) 2004-09-24 2009-06-30 Эмджин Инк. МОЛЕКУЛЫ С МОДИФИЦИРОВАННЫМ Fc ФРАГМЕНТОМ
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) * 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
JP5525689B2 (ja) * 2004-11-02 2014-06-18 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ 過剰増殖性障害を処置するための組成物および方法
US20090118132A1 (en) * 2004-11-04 2009-05-07 Roche Molecular Systems, Inc. Classification of Acute Myeloid Leukemia
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
US8809287B2 (en) * 2004-11-15 2014-08-19 Icahn School Of Medicine At Mount Sinai Compositions and methods for altering Wnt autocrine signaling
EP1812594B1 (fr) 2004-11-18 2013-01-09 Eppendorf Array Technologies Quantification en temps reel de cibles multiples sur un microreseau
EP2283831A3 (fr) 2004-12-03 2013-10-23 Merck Sharp & Dohme Corp. Biomarqueurs pour la présélection des patients pour la thérapie anti-IGF1R
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US7842794B2 (en) 2004-12-17 2010-11-30 Roche Molecular Systems, Inc. Reagents and methods for detecting Neisseria gonorrhoeae
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US7713695B2 (en) 2005-02-07 2010-05-11 Genenews, Inc. Mild osteoarthritis biomarkers and uses thereof
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
CA2603093A1 (fr) 2005-03-31 2006-10-05 Agensys, Inc. Anticorps et molecules correspondantes qui se fixent aux proteines 161p2f10b
EP3796003A1 (fr) 2005-04-04 2021-03-24 Biogen MA Inc. Procédés pour évaluer une réponse immunitaire à un agent thérapeutique
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
CN101248180B (zh) 2005-04-18 2013-09-25 米托米克斯公司 作为检测日光照射、前列腺癌和其它癌症的诊断工具的线粒体突变及重排
US20060240496A1 (en) * 2005-04-21 2006-10-26 Lakshmi Anne Immunogens, derivatives and immunoassay for ethyl glucuronide
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
WO2006125117A2 (fr) 2005-05-18 2006-11-23 Novartis Ag Procedes de diagnostic et de traitement de maladies ayant une composante auto-immune et/ou inflammatoire
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
ES2511218T5 (es) 2005-06-20 2017-12-07 Advanced Cell Diagnostics, Inc. Kits y productos para detección de ácidos nucleicos en células individuales y para identificación de células raras en grandes poblaciones de células heterogéneas
US7695975B2 (en) 2005-06-23 2010-04-13 Siemens Healthcare Diagnostics Inc. Detection of adulterated samples
CA2615460A1 (fr) * 2005-08-08 2007-02-15 Onconon, Llc Compositions d'anticorps, methodes de traitement de maladie neoplasique et methodes de regulation de la fertilite
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
EP3190125A1 (fr) 2005-08-31 2017-07-12 Merck Sharp & Dohme Corp. Anticorps anti-il-23 de synthèse
US7608395B2 (en) * 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
WO2007041340A2 (fr) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Cellules microfluidiques a arrangements paralleles de molecules d'adn individuelles
US20070202515A1 (en) * 2005-10-12 2007-08-30 Pathologica, Llc. Promac signature application
AU2006304883A1 (en) 2005-10-21 2007-04-26 Genenews Inc. Method and apparatus for correlating levels of biomarker products with disease
BRPI0618338A2 (pt) 2005-11-07 2011-08-23 Scripps Resarch Inst uso de inibidor de sinalização de fator tecidual, método para identificar um agente que inibe a sinalização de tf/viia, composições farmacêuticas e kit
US8124351B2 (en) 2005-11-18 2012-02-28 Board Of Regents, The University Of Texas System Quantification of fusion proteins and their activity from chromosomal translocation
JP2009523410A (ja) 2005-12-08 2009-06-25 ノバルティス アクチエンゲゼルシャフト 遺伝子転写に対するｆｇｆｒ３の阻害剤の効果
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
EP2674440B1 (fr) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Ensembles bioactifs à base d'immunoglobuline multivalent
WO2007071448A2 (fr) 2005-12-23 2007-06-28 Partnership & Corp. Technology Transfer Peptides synthetiques utilises comme inhibiteurs de la secretion des neurotransmetteurs et comme inducteurs de la relaxation cellulaire
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
CA2913655A1 (fr) 2006-01-27 2007-08-09 Biogen Ma Inc. Antagonistes des recepteurs nogo
AR059193A1 (es) 2006-01-31 2008-03-12 Bayer Schering Pharma Ag Modulacion de la actividad de mdl-1 para el tratamiento de enfermedades inflamatorias
JP5706602B2 (ja) 2006-02-08 2015-04-22 ジェンザイム・コーポレーション ニーマンピック病ａ型に対する遺伝子治療
DE102006009516B4 (de) * 2006-02-28 2007-12-06 Analyticon Biotechnologies Ag Testvorrichtung, Herstellungsverfahren dafür und Testverfahren
ES2752137T3 (es) 2006-02-28 2020-04-03 Biogen Ma Inc Métodos para tratar enfermedades inflamatorias y autoinmunes con natalizumab
WO2007103112A2 (fr) 2006-03-03 2007-09-13 Elan Pharmaceuticals, Inc. Procédés de traitement de maladies inflammatoires et auto-immunes avec du natalizumab
WO2007109733A2 (fr) 2006-03-21 2007-09-27 The Johns Hopkins University Marqueurs de diagnostic et de pronostic et strategies de traitement de la sclerose en plaques
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
KR20090029184A (ko) * 2006-04-07 2009-03-20 더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 항체 조성물 및 신생물성 질병의 치료 방법
MX2008013508A (es) 2006-04-21 2008-10-31 Novartis Ag Composiciones farmaceuticas de anticuerpos antagonistas anti-cd40.
FR2900341B1 (fr) 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
MX2008014155A (es) 2006-05-09 2009-02-25 Musc Found For Res Dev Deteccion de insuficiencia cardiaca diastolica por proteasa y determinacion de perfil plasmatico de inhibidor de proteasa.
US7799534B2 (en) * 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7642338B2 (en) * 2006-06-20 2010-01-05 Siemens Healthcare Diagnostics Inc. Tacrolimus standard and methods of using same
WO2008005429A2 (fr) 2006-07-03 2008-01-10 Charles David Adair Composition servant à moduler l'expression de molécules d'adhérence cellulaire
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
US8445222B2 (en) * 2006-07-11 2013-05-21 Musc Foundation For Research Development Predicting heart failure following myocardial infarction by protease and protease inhibitor profiling
MX2009000395A (es) 2006-07-14 2009-01-29 Chemocentryx Inc Triazolil fenil bencenosulfonamidas.
EP2053961A4 (fr) * 2006-08-09 2013-05-01 Biogen Idec Inc Procédé de distribution d'un médicament
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
EP2061900A2 (fr) 2006-08-25 2009-05-27 Oncotherapy Science, Inc. Marqueurs pronostiques et cibles thérapeutiques s'appliquant au cancer du poumon
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US7985542B2 (en) * 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
WO2008031051A2 (fr) 2006-09-08 2008-03-13 United Therapeutics Corporation Diagnostic clinique d'une fibrose hépatique en utilisant une nouvelle numération globulaire de biomarqueurs de protéines du sérum humain
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
JP2010505431A (ja) 2006-10-11 2010-02-25 ジャンセン ファーマシューティカ エヌ．ヴェー． 過敏性腸症候群の処置および予防のための組成物および方法
EP1912067A1 (fr) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Procédé de quantification d'un composé cible issu d'un échantillon biologique à l'aide de puces à microreseau
EP2076591A2 (fr) 2006-10-20 2009-07-08 Danisco US, INC., Genencor Division Polyol oxydases
MX2009004460A (es) * 2006-10-26 2009-07-09 Abbott Lab Inmunoensayo de analitos en muestras que contienen anticuerpos anti-analito endogenos.
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
EP2089710B1 (fr) 2006-10-27 2014-10-01 Janssen Pharmaceutica NV Procédé d'établissement de profils pharmacologiques de composés
EP2450456A3 (fr) 2006-11-02 2012-08-01 Yale University Evaluation de la compétence d'oocyte
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
WO2008067552A2 (fr) * 2006-11-30 2008-06-05 Fluidigm Corporation Procédé et appareil pour l'analyse d'échantillons biologiques
WO2008067547A2 (fr) 2006-11-30 2008-06-05 Research Development Foundation Bibliothèques d'immunoglobulines améliorées
CA2671538A1 (fr) 2006-12-14 2008-06-26 Leonard G. Presta Anticorps anti-tslp technique
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US8506499B2 (en) * 2007-01-04 2013-08-13 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
US8642295B2 (en) * 2007-01-11 2014-02-04 Erasmus University Medical Center Circular chromosome conformation capture (4C)
US9511075B2 (en) 2007-01-12 2016-12-06 The University Of Maryland, Baltimore Targeting NCCA-ATP channel for organ protection following ischemic episode
MX2009008021A (es) 2007-01-25 2009-08-07 Danisco Produccion de una aciltransferasa de lipido de celulas de bacillus licheniformis transformadas.
EP2111550B1 (fr) 2007-01-26 2011-11-30 University Of Louisville Research Foundation, Inc. Méthodes de détection d'autoanticorps pour diagnostiquer et caractériser des troubles
US20080220498A1 (en) * 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) * 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
WO2008103319A2 (fr) 2007-02-16 2008-08-28 Ark Diagnostics, Inc. Composés et procédés destinés à être utilisés dans la détection de la gabapentine
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
EP2426145B1 (fr) 2007-02-23 2017-01-18 Merck Sharp & Dohme Corp. Anticorps anti-23p19 de synthèse
AR065420A1 (es) 2007-02-23 2009-06-03 Schering Corp Anticuerpos anti-il-23 p19 de ingenieria
AU2008219684B2 (en) 2007-02-28 2014-04-17 Merck Sharp & Dohme Corp. Engineered anti-IL-23R antibodies
CA2680556A1 (fr) 2007-03-12 2008-09-18 Miraculins Inc. Biomarqueurs du cancer de la prostate et utilisations de ceux-ci
DK2865755T3 (en) 2007-03-30 2017-05-15 Engeneic Molecular Delivery Pty Ltd BACTERIAL DERIVATIVE INTACT MINICELLS WITH REGULATORY RNA
JP5684563B2 (ja) 2007-04-06 2015-03-11 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ カルバペネマーゼ遺伝子の同定のための組成物および方法
CA2683559C (fr) 2007-04-13 2019-09-24 Dana Farber Cancer Institute, Inc. Methodes de traitement d'un cancer resistant a des agents therapeutiques anti-erbb
US20100255004A1 (en) * 2007-04-13 2010-10-07 Dana Farber Cancer Institute Receptor tyrosine kinase profiling
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
AU2008247819B2 (en) 2007-05-01 2013-02-14 Research Development Foundation Immunoglobulin Fc libraries
WO2009009215A2 (fr) * 2007-05-02 2009-01-15 Emory University Amélioration d'incorporation de glycoprotéine dans des particules de type viral
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
WO2009000089A1 (fr) * 2007-06-28 2008-12-31 University Of Saskatchewan Compositions immunomodulantes et procédés de traitement d'une maladie par des peptides de défense modifiés de l'hôte
PL2175859T3 (pl) 2007-07-12 2012-09-28 Chemocentryx Inc Skondensowane heteroarylopirydylo- i fenylo-benzenosulfonamidy jako modulatory CCR2 do leczenia zapalenia
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
WO2009020923A1 (fr) 2007-08-03 2009-02-12 Musc Foundation For Research Development Anticorps monoclonaux humains et procédés de production
CA2694832A1 (fr) 2007-08-06 2009-02-12 Orion Genomics Llc Nouveaux polymorphismes nucleotidiques uniques et combinaisons de nouveaux polymorphismes connus permettant de determiner l'expression specifique d'allele du gene igf2
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
EP2283028A2 (fr) 2007-08-08 2011-02-16 The Board of Regents of The University of Texas System Peptides ciblant vegfr-1/nrp-1
WO2009023676A1 (fr) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Système de microréseau avec spécificité de séquence améliorée
WO2009023733A1 (fr) * 2007-08-13 2009-02-19 Trustees Of Tufts College Procédés et microréseaux pour détecter des virus entériques
EP2203749B1 (fr) 2007-10-05 2012-08-29 Affymetrix, Inc. Dosages à base de particules hautement multiplexées
AU2008312575B2 (en) * 2007-10-15 2012-02-23 Idexx Laboratories, Inc. Feline pancreatic lipase
WO2009062027A1 (fr) * 2007-11-07 2009-05-14 Beckman Coulter, Inc. Procédés de dosage sans fractionnement utilisant des enzymes génératrices de péroxyde
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
CA2711499C (fr) 2008-01-10 2018-09-25 Research Development Foundation Vaccins et diagnostics pour les ehrlichioses
EP3103467A1 (fr) 2008-02-07 2016-12-14 Cornell University Procédés de prévention ou de traitement de la résistance à l'insuline
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
AU2009227935B2 (en) 2008-03-28 2015-07-09 Mdna Life Sciences Inc. Aberrant mitochondrial DNA, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (fr) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) PCR en temps réel de cibles sur un micro-réseau
GB0807161D0 (en) * 2008-04-18 2008-05-21 Danisco Process
JP2011519034A (ja) * 2008-04-23 2011-06-30 ルミネックス コーポレーション 生物学的起原の出発材料中に見出される複数の検体のスタンダードを作成する方法
WO2009132124A2 (fr) 2008-04-24 2009-10-29 The Trustees Of Columbia University In The City Of New York Motifs géométriques et bicouches lipidiques utilisables pour l'organisation de molécules d'adn et leurs utilisations
EP2281034B1 (fr) 2008-04-30 2015-10-21 DuPont Nutrition Biosciences ApS Procédé d'utilisation de l'alcool déshydrogénase de la Pseudoglucanobacter saccharoketogenes
EP2291390B1 (fr) * 2008-05-22 2014-11-05 Centre National de la Recherche Scientifique (CNRS) Nouveaux composés optiquement purs pour une efficacité thérapeutique améliorée
PE20141435A1 (es) 2008-07-16 2014-10-22 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano
EP2303923B1 (fr) 2008-07-16 2015-06-24 Institute for Research in Biomedicine Anticorps neutralisant les cytomégalovirus humains et leur utilisation
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
WO2010010467A2 (fr) * 2008-07-25 2010-01-28 Institute For Research In Biomedicine Anticorps neutralisant anti-virus influenza a et leurs utilisations
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
EP2349335B1 (fr) 2008-10-24 2013-08-07 ARK Diagnostics, Inc. Immunodosages du lévétiracétam
US20100135904A1 (en) 2008-11-07 2010-06-03 Research Development Foundation Compositions and methods for the inhibition of cripto / grp78 complex formation and signaling
US20110287088A1 (en) 2008-12-03 2011-11-24 Research Development Foundation Modulation of olfml-3 mediated angiogenesis
WO2010065954A2 (fr) 2008-12-05 2010-06-10 Abraxis Bioscience, Llc Peptides de liaison à sparc et leurs utilisations
WO2010066252A1 (fr) 2008-12-09 2010-06-17 Dako Denmark A/S Procédé d'évaluation de prétraitement
WO2010068757A1 (fr) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions et procédés utiles pour détecter et traiter des maladies associées à des ruptures du chromosome 16p
WO2010093820A2 (fr) 2009-02-11 2010-08-19 Orion Genomics Llc Combinaisons de polymorphismes destinées à déterminer l'expression spécifique des allèles d'igf2
IL313131A (en) 2009-02-11 2024-07-01 Caris Mpi Inc Molecular characterization of tumors
WO2010096658A1 (fr) 2009-02-19 2010-08-26 The Cleveland Clinic Foundation Corine en tant que marqueur pour une insuffisance cardiaque
US9347947B2 (en) * 2009-03-12 2016-05-24 Siemens Healthcare Diagnostics Inc. Immunoassays employing non-particulate chemiluminescent reagent
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
PT2411410E (pt) * 2009-03-27 2015-10-09 Gojo Ind Inc Composições e métodos para screening e utilização de compostos que antagonizam interações esporo-superfície
AU2010234238B2 (en) 2009-03-27 2016-07-28 Mdna Life Sciences Inc. Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor
US9447467B2 (en) 2009-04-21 2016-09-20 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
EP2425253B1 (fr) 2009-05-01 2017-03-22 Dako Denmark A/S Nouveau cocktail d'anticorps
US8889364B2 (en) * 2009-05-14 2014-11-18 The Chancellor, Masters And Scholars Of The University Of Oxford Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
AU2010250810B2 (en) 2009-05-19 2014-03-20 Dupont Nutrition Biosciences Aps Use
US20120128673A1 (en) 2009-05-20 2012-05-24 Schering Corporation Modulation of pilr receptors to treat microbial infections
BRPI1013012A2 (pt) 2009-06-02 2016-10-18 Opko Health Inc identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas
KR20120103431A (ko) 2009-06-25 2012-09-19 대니스코 에이/에스 단백질
US20110165595A1 (en) * 2009-07-13 2011-07-07 Catanzaro Brian E Apparatus and methods for processing a whole blood sample
ES2652340T3 (es) 2009-07-17 2018-02-01 Bioatla Llc Selección y evolución simultáneas e integradas de rendimiento y expresión de proteínas humanas en huéspedes de producción
EP2473531A4 (fr) 2009-09-03 2013-05-01 Merck Sharp & Dohme Anticorps anti-gitr
US20130023433A1 (en) 2009-09-28 2013-01-24 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
CA2777053A1 (fr) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Recepteurs de lymphocytes t a chaine unique humains
EP2485762B1 (fr) 2009-10-11 2017-12-13 Biogen MA Inc. Tests associés à un anti-vla-4
CA2779223A1 (fr) 2009-10-27 2011-05-12 Caris Mpi, Inc. Profilage moleculaire pour medecine personnalisee
CN102770529B (zh) 2009-11-17 2018-06-05 Musc研究发展基金会 针对人核仁素的人单克隆抗体
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
US20130183326A9 (en) 2009-11-20 2013-07-18 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US20110136141A1 (en) * 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US8691227B2 (en) 2009-12-17 2014-04-08 Merck Sharp & Dohme Corp. Methods of treating multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease using agonists antibodies to PILR-α
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
RS56977B1 (sr) 2010-01-11 2018-05-31 Biogen Ma Inc Test za antitela protiv jc virusa
US8697078B2 (en) 2010-01-27 2014-04-15 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
US20130171621A1 (en) 2010-01-29 2013-07-04 Advanced Cell Diagnostics Inc. Methods of in situ detection of nucleic acids
US8574832B2 (en) 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
AU2011213609B2 (en) 2010-02-08 2016-11-03 Agensys, Inc. Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
WO2011114251A1 (fr) 2010-03-18 2011-09-22 Danisco A/S Produits alimentaires
WO2011127150A2 (fr) 2010-04-06 2011-10-13 Massachusetts Institute Of Technology Profilage de l'expression génique faisant appel à un nombre réduit de mesures concernant des transcrits
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
EP2567232A1 (fr) 2010-05-07 2013-03-13 AbbVie Inc. Procédés de prédiction de la sensibilité à un traitement à l'aide d'un inhibiteur de tyrosine kinase ciblé
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
WO2011146479A1 (fr) 2010-05-18 2011-11-24 The Texas A&M University System Procédé et composition pour le diagnostic et le suivi de maladies inflammatoires
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
WO2012006056A2 (fr) 2010-06-29 2012-01-12 Oregon Health & Science University Ccr6 en tant que biomarqueur de la maladie d'alzheimer
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
EP2407242A1 (fr) 2010-07-13 2012-01-18 Dublin City University Analyse de clone directe et technologie de sélection
WO2012009627A2 (fr) 2010-07-16 2012-01-19 Vanderbilt University Processeur à faible ressource utilisant des valves de tension superficielle pour extraire, concentrer et détecter des espèces moléculaires
CN103003696B (zh) 2010-07-16 2016-06-01 生物蛋白有限公司 蛋白演化的新方法
AU2011280967B2 (en) 2010-07-23 2014-09-11 Luminex Corporation Co-coupling to control reactivity of reagents in immunoassays
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
US8778699B2 (en) 2010-08-04 2014-07-15 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
AU2011305696A1 (en) 2010-09-20 2013-05-02 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
EP3409287B9 (fr) 2010-09-29 2021-07-21 Agensys, Inc. Conjugués anticorps-médicaments (adc) se liant aux protéines 191p4d12
CN103402531A (zh) 2010-10-04 2013-11-20 国家科学研究中心 作为抗生素治疗的多价合成化合物
EP2441520A1 (fr) 2010-10-12 2012-04-18 Eppendorf AG Application en temps réel et détection basée sur un micro-réseau de cibles d'acides nucléiques dans un dosage sur puce de flux
CN104849472A (zh) * 2010-10-21 2015-08-19 领先细胞医疗诊断有限公司 用于原位检测核酸的超灵敏方法
WO2012075111A1 (fr) 2010-11-30 2012-06-07 Novartis Ag Utilisation d'anticorps anti-cd40 en thérapie combinée contre des cancers associés aux cellules b
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
CN103620405B (zh) 2010-12-31 2016-05-25 生物蛋白有限公司 全面单克隆抗体产生
EP3567121B1 (fr) 2011-01-17 2023-08-30 Life Technologies Corporation Workflow pour la détection de ligands à l'aide d'acides nucléiques
DK2668290T3 (en) 2011-01-28 2017-09-18 Advanced Cell Diagnostics Inc RNASCOPE® HPV ASSAY FOR DETERMINING HPV STATUS OF CANCER AND HEALTH CANCER AND LESSIONS
AU2012214643B2 (en) 2011-02-07 2016-12-15 Research Development Foundation Engineered immunoglobulin Fc polypeptides
EP2678042B1 (fr) 2011-02-23 2018-05-09 The Board of Trustees of the University of Illionis Dendron-hélices amphiphiles, micelles de ceux-ci et utilisations
US9057107B2 (en) 2011-03-08 2015-06-16 King Abdullah University Of Science And Technology Molecular biomarker set for early detection of ovarian cancer
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
CN103476949A (zh) 2011-03-28 2013-12-25 诺瓦提斯公司 与细胞周期蛋白依赖性激酶抑制剂相关的标志物
IL281714B2 (en) 2011-04-01 2023-11-01 Immunogen Inc Methods for increasing the effectiveness of FOLR1 cancer therapy
EP2694095B1 (fr) 2011-04-05 2018-03-07 Longevity Biotech, Inc. Compositions comprenant des analogues du glucagon et leurs procédés de fabrication et d'utilisation
AU2012241055A1 (en) 2011-04-08 2013-08-15 Danisco Us, Inc. Compositions
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
WO2012161288A1 (fr) 2011-05-20 2012-11-29 Abbott Japan Co. Ltd. Procédés et réactifs d'immunodosage pour la diminution d'une liaison non spécifique
EP2709728B1 (fr) 2011-05-20 2019-01-23 Oligomerix, Inc. Procédés d'utilisation de protéase tau
PL3575792T3 (pl) 2011-05-31 2023-03-27 Biogen Ma Inc. Metoda oceny ryzyka postępującej wieloogniskowej leukoencefalopatii (pml)
AU2012262154B2 (en) 2011-05-31 2016-08-04 Idexx Laboratories, Inc. Detection of degradation products of feline NT-proBNP
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
WO2013010170A1 (fr) 2011-07-14 2013-01-17 Lovell Mark A Procédé de détection de la maladie d'alzheimer à partir d'un échantillon de sérum
HRP20190714T1 (hr) 2011-07-18 2019-06-14 Institute For Research In Biomedicine Neutralizirajuća protutijela anti-influenca a virusa i njihova uporaba
WO2013012924A2 (fr) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Molécules manipulées ciblant un microbe et leurs utilisations
AU2012294814A1 (en) 2011-08-05 2014-02-27 Research Development Foundation Improved methods and compositions for modulation of Olfml3 mediated angiogenesis
ES2671238T3 (es) 2011-08-12 2018-06-05 Siemens Healthcare Diagnostics Inc. Detección de esteroides sexuales
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
EP2744828A4 (fr) 2011-08-16 2014-12-31 Univ Emory Agents spécifiques de liaison à jaml, anticorps, et leurs utilisations associées
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
AU2012325604B2 (en) 2011-10-21 2017-08-03 Augurex Life Sciences Corp. Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis
CN102507917A (zh) * 2011-11-01 2012-06-20 四川金域医学检验中心有限公司 丙戊酸均相酶免疫快速检测试剂盒
US20140348818A1 (en) 2011-12-29 2014-11-27 Baylor Research Institute Biomarkers of kawasaki disease
AU2012367247B2 (en) 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
US8771964B2 (en) 2012-02-02 2014-07-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detection of methadone metabolite
WO2013130811A1 (fr) 2012-02-29 2013-09-06 Chemocentryx, Inc. Sulfonamides de pyrazol-1-yl benzène convenant comme antagonistes de ccr9
US8586322B2 (en) 2012-03-07 2013-11-19 Siemens Healthcare Diagnostics, Inc Sandwich assay for immunosuppressant drugs
NZ630920A (en) 2012-03-20 2017-01-27 Humabs Biomed Sa Antibodies that neutralize rsv, mpv and pvm and uses thereof
DK2828284T3 (da) 2012-03-20 2019-06-11 Biogen Ma Inc Jcv-neutraliserende antistoffer
US12195550B2 (en) 2012-03-30 2025-01-14 The United States Of America As Represented By The Department Of Veterans Affairs Targeting intracellular target-binding determinants with intracellular antibodies
US9283272B2 (en) 2012-03-30 2016-03-15 The United States Of America As Represented By The Department Of Veterans Affairs Targeting intracellular target-binding determinants with intracellular antibodies
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
EP2841101B1 (fr) 2012-04-26 2019-08-07 University Of Chicago Compositions et procédés associés à des anticorps qui neutralisent l'activité coagulase dans une maladie à staphylococcus aureus
US9658218B2 (en) 2012-05-07 2017-05-23 Siemens Healthcare Diagnostics Inc. Determination of total analyte concentration
DK2847231T3 (da) 2012-05-10 2019-10-14 Bioatla Llc Multispecifikke monoklonale antistoffer
EP2855521A4 (fr) 2012-05-24 2016-03-02 Mountgate Group Ltd Compositions et procédés associés à la prévention et au traitement d'une infection rabique
PL2854910T3 (pl) 2012-06-01 2020-07-27 Icahn School Of Medicine At Mount Sinai Poziomy ceramidu w leczeniu i zapobieganiu infekcjom
AU2013277971B2 (en) 2012-06-22 2018-11-15 Htg Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
ES2704857T3 (es) 2012-06-27 2019-03-20 Siemens Healthcare Diagnostics Inc Composiciones y métodos para la evaluación de la mezcla de líquidos
ES2661883T3 (es) 2012-07-09 2018-04-04 Novartis Ag Biomarcadores asociados con inhibidores de CDK
US20150173883A1 (en) 2012-07-18 2015-06-25 President And Fellows Of Harvard College Modification of surfaces for simultaneous repellency and targeted binding of desired moieties
AU2013295652B2 (en) 2012-07-27 2018-02-08 The Board Of Trustees Of The University Of Illinois Engineering T-cell receptors
US9371568B2 (en) 2012-07-31 2016-06-21 Novartis Ag Markers associated with human double minute 2 inhibitors
EP3494996B1 (fr) 2012-08-23 2026-04-15 Agensys, Inc. Conjugués anticorps-médicament (adc) qui se lient aux protéines 158p1d7
WO2014059442A2 (fr) 2012-10-12 2014-04-17 Arizona Board Agents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Réactifs à base d'anticorps qui reconnaissent spécifiquement des formes oligomériques toxiques de tau
US10226744B2 (en) 2012-10-19 2019-03-12 Danisco Us Inc Stabilization of biomimetic membranes
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
AU2013334583B2 (en) 2012-10-24 2018-09-13 Research Development Foundation JAM-C antibodies and methods for treatment of cancer
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
CA2897053C (fr) 2013-01-02 2020-10-13 N-Dia, Inc. Procedes permettant de prevoir le terme chez une femme enceinte
EP2945942B1 (fr) 2013-01-18 2018-05-09 ARK Diagnostics, Inc. Immunodosages de viroconazole
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
EP2951290B1 (fr) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Procédé de génération de cellules épithéliales pigmentaires rétiniennes (epr) à partir de cellules souches pluripotentes induites (cspi)
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
EP3885446A1 (fr) 2013-02-01 2021-09-29 The Regents of The University of California Procédés pour assemblage du génome et phasage d'haplotype
US9920136B2 (en) 2013-02-13 2018-03-20 Ark Diagnostics, Inc. Posaconazole immunoassays
US20160008282A1 (en) 2013-02-22 2016-01-14 The Board Of Trustees Of The Universityof Illinois Transdermal Drug Delivery Using Amphiphilic Dendron-Coil Micelles
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
EP2970479B1 (fr) 2013-03-14 2019-04-24 Novartis AG Anticorps dirigés contre notch 3
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
WO2014159242A1 (fr) 2013-03-14 2014-10-02 Novartis Ag Mutants de notch 3 et leurs utilisations
PT3524617T (pt) 2013-03-15 2023-07-12 Gladiator Biosciences Inc Domínios gla como agentes terapêuticos
WO2014144666A2 (fr) 2013-03-15 2014-09-18 The University Of Chicago Procédés et compositions associés à l'activité des lymphocytes t
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
US20160091485A1 (en) 2013-04-25 2016-03-31 The Broad Institute, Inc. Markers for ezh2 inhibitors
JP6472789B2 (ja) 2013-05-14 2019-02-20 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． 受容体含有安定化液剤
WO2014190040A1 (fr) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Compositions se liant à l'hème manipulées et leurs utilisations
EP3004334A4 (fr) 2013-05-28 2016-12-21 Biogen Ma Inc Méthodes d'évaluation de risque de développement d'une lemp
EP3008201B1 (fr) 2013-06-12 2019-08-07 The General Hospital Corporation Procédés pour détection multiplexe de molécules cibles et leurs utilisations
CA2915973A1 (fr) 2013-06-18 2014-12-24 Dnatrix, Inc. Traitement du cancer du cerveau a l'aide d'adenovirus oncolytique
CA2916694C (fr) 2013-06-28 2023-01-17 Baylor Research Institute Immunotherapie par ciblage d'asgpr de cellules dendritiques pour la sclerose en plaques
JP6510518B2 (ja) 2013-08-01 2019-05-08 アジェンシス，インコーポレイテッド Ｃｄ３７タンパク質に結合する抗体薬物結合体（ａｄｃ）
CN114621346B (zh) 2013-08-21 2025-06-10 德克萨斯州大学系统董事会 用于靶向连接蛋白半通道的组合物和方法
AU2014312086B2 (en) 2013-08-30 2020-03-12 Immunogen, Inc. Antibodies and assays for detection of folate receptor 1
EP3733244A1 (fr) 2013-10-02 2020-11-04 Medlmmune, LLC Anticorps neutralisant la grippe a et leurs utilisations
EP3052193B1 (fr) 2013-10-03 2018-01-31 Oklahoma Medical Research Foundation Biomarqueurs d'activité, de l'intensité et de l'éruption de la maladie du lupus érythémateux disséminé
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
EP3060917B1 (fr) 2013-10-24 2019-05-15 Siemens Healthcare Diagnostics Inc. Dosages pour analytes macromoléculaires
CA2965327C (fr) 2013-11-08 2023-05-09 The Board Of Regents Of The University Of Texas System Anticorps vh4 diriges contre les astrocytes et les neurones de la matiere grise
EP3068783B1 (fr) 2013-11-15 2020-09-23 The Board of Trustees of the Leland Stanford Junior University Les agonistes de récepteur 2 d'hypocrétine pur l'utilisation dans le traitement d'une insuffisance cardiaque
MX2016006584A (es) 2013-11-20 2016-09-06 Univ Iowa Res Found Métodos y composiciones para tratar los depósitos de amiloide.
EP3071594A4 (fr) 2013-11-22 2017-05-03 The Board of Trustees of the University of Illionis Récepteurs modifiés de haute affinité pour les lymphocytes t humains
ES2740851T3 (es) 2013-12-13 2020-02-06 Siemens Healthcare Diagnostics Inc Agente de tratamiento previo en ensayos sin aglutinación
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
ES2670991T3 (es) 2013-12-18 2018-06-04 Siemens Healthcare Diagnostics Inc. Detección de enfermedad endotelial
EP3083658B1 (fr) 2013-12-18 2019-05-08 President and Fellows of Harvard College Détection de bacteries gram positif à l'aide de crp
DK3083936T3 (en) 2013-12-19 2018-10-22 Danisco Us Inc USE OF HYDROPHOBINES TO INCREASE GAS TRANSFER IN AEROBE FERMENTATION PROCESSES
US11293929B2 (en) 2014-01-07 2022-04-05 Bioatla, Inc. Proteins targeting orthologs
JP7037884B2 (ja) 2014-01-13 2022-03-17 ベイラー リサーチ インスティテュート Ｈｐｖ及びｈｐｖ関連疾患に対する新規のワクチン
US10059775B2 (en) 2014-01-29 2018-08-28 Dana-Farber Cancer Institute, Inc. Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
US20150247204A1 (en) 2014-02-07 2015-09-03 The General Hopital Corporation Differential diagnosis of hepatic neoplasms
WO2015123565A1 (fr) 2014-02-14 2015-08-20 The General Hospital Corporation Méthodes de diagnostic d'une maladie liée à l'igg4
WO2015131099A1 (fr) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnostic du myélome multiple et du lymphome
EP3502698A1 (fr) 2014-05-05 2019-06-26 MicroBPlex, Inc. Milieux préparés avec des anticorps nouvellement synthétisés et leurs utilisations
DK3140653T3 (da) 2014-05-08 2022-06-20 Novodiax Inc Direkte immunhistokemianalyse
WO2015179435A1 (fr) 2014-05-19 2015-11-26 Bayer Healthcare Llc Anticorps monoclonaux humanisés optimisés dirigés contre la protéine c activée et leurs utilisations
CN106661115A (zh) 2014-06-27 2017-05-10 西门子医疗保健诊断公司 对维生素d差向异构体特异性的结合配偶体
ES2853525T3 (es) 2014-06-27 2021-09-16 Siemens Healthcare Diagnostics Inc Parejas de unión específicas para epímeros de vitamina D en ensayos de vitamina D
CN119161468A (zh) 2014-07-15 2024-12-20 免疫医疗有限责任公司 中和抗乙型流感抗体及其用途
CA2956925C (fr) 2014-08-01 2024-02-13 Dovetail Genomics, Llc Marquage d'acides nucleiques pour l'assemblage de sequences
EP3191592A1 (fr) 2014-09-11 2017-07-19 Novartis AG Inhibition de prmt5 dans le traitement de maladies liées à une déficience en mtap
CN106470697B (zh) 2014-09-16 2019-10-25 兴盟生物医药(苏州)有限公司 抗egfr抗体以及其用途
MX2017004344A (es) 2014-10-06 2017-06-07 Chemocentryx Inc COMPOSICIONES Y METODOS PARA TRATAR ENFERMEDAD INFLAMATORIA DE INTESTINO USANDO UNA TERAPIA DE COMBINACION DE INHIBIDORES DE MOLECULA PEQUENA DEL RECEPTOR DE QUIMIOCINA C-C TIPO 9 (CCR9) Y ANTICUERPOS BLOQUEADORES ANTI-A4ß7 INTEGRINA.
WO2016055950A1 (fr) 2014-10-08 2016-04-14 Novartis Ag Combinaison d'anticorps de neutralistion du cytomégalovirus humain
US20170253921A1 (en) 2014-10-13 2017-09-07 Life Technologies Corporation Methods, kits & compositions for determining gene copy numbers
DE102015220401B4 (de) 2014-10-20 2022-12-29 Gen-Probe Incorporated Erythrozyten-Lyselösung
EP3172329A1 (fr) 2014-10-24 2017-05-31 Danisco US Inc. Procédé de production d'alcool au moyen d'une tripeptidyl peptidase
WO2016062855A1 (fr) 2014-10-24 2016-04-28 Dupont Nutrition Biosciences Aps Tripeptidyl-peptidases tolérant la proline et leurs utilisations
WO2016075546A2 (fr) 2014-11-14 2016-05-19 Antonio Lanzavecchia Anticorps qui neutralisent le virus ebola et leurs utilisations
BR122020023406B1 (pt) 2014-11-18 2023-10-31 Institut Pasteur Anticorpos que neutralizam de modo potente vírus da raiva e outros lissavírus, moléculas de ácido nucleico, vetor, célula isolada, composição farmacêutica, usos dos mesmos, e kit de partes
EP3754027A1 (fr) 2014-12-01 2020-12-23 The Broad Institute, Inc. Procédé de détermination in situ de proximité d'acide nucléique
EP3227446A1 (fr) 2014-12-01 2017-10-11 Novartis AG Compositions et méthodes pour le diagnostic et le traitement du cancer de la prostate
SG10202012249YA (en) 2014-12-08 2021-01-28 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
WO2016100116A1 (fr) 2014-12-17 2016-06-23 Siemens Healthcare Diagnostics Inc. Conception de dosage en sandwich pour des petites molécules
WO2016102950A1 (fr) 2014-12-23 2016-06-30 4D Pharma Research Limited Immunomodulation
SG11201704814SA (en) 2014-12-23 2017-07-28 4D Pharma Res Ltd Pirin polypeptide and immune modulation
JP6724023B2 (ja) 2015-02-09 2020-07-15 リサーチ ディベロップメント ファウンデーション 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド
NZ734854A (en) 2015-02-17 2022-11-25 Dovetail Genomics Llc Nucleic acid sequence assembly
CA2977499C (fr) 2015-02-25 2023-10-03 Vanderbilt University Neutralisation a mediation anticorps du virus de marburg
US9958464B2 (en) 2015-03-03 2018-05-01 Ark Diagnostics, Inc. Pregabalin immunoassays
ES2884844T3 (es) 2015-03-09 2021-12-13 Agensys Inc Conjugados de anticuerpo fármaco (ADC) que se unen a proteínas FLT3
EP3268462B1 (fr) 2015-03-11 2021-08-11 The Broad Institute, Inc. Couplage de génotype et de phénotype
US11807896B2 (en) 2015-03-26 2023-11-07 Dovetail Genomics, Llc Physical linkage preservation in DNA storage
AU2016243124A1 (en) 2015-03-27 2017-11-02 University Of Southern California CAR T-cell therapy directed to LHR for the treatment of solid tumors
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
WO2016182984A1 (fr) 2015-05-08 2016-11-17 Centrillion Technology Holdings Corporation Terminateurs réversibles à liaison disulfure
WO2016187356A1 (fr) 2015-05-18 2016-11-24 Agensys, Inc. Anticorps qui se lient aux protéines axl
WO2016187354A1 (fr) 2015-05-18 2016-11-24 Agensys, Inc. Anticorps se liant à des protéines axl
CN113480640B (zh) 2015-06-01 2024-07-30 免疫医疗有限责任公司 中和抗流感结合分子及其用途
JP7010473B2 (ja) 2015-06-04 2022-02-10 ユニバーシティ オブ サザン カリフォルニア Ｌｙｍ－１およびｌｙｍ－２標的化ｃａｒ細胞免疫療法
HRP20191949T1 (hr) 2015-06-15 2020-01-24 4D Pharma Research Limited Blautia stercosis i wexlerae za upotrebu u liječenju upalnih i autoimunih bolesti
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
WO2016203221A1 (fr) 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprenant des souches bactériennes
ME03511B (fr) 2015-06-15 2020-04-20 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3314004A1 (fr) 2015-06-26 2018-05-02 DuPont Nutrition Biosciences ApS Aminopeptidases pour hydrolysats de protéines
EP3313871A1 (fr) 2015-06-26 2018-05-02 Institute for Research in Biomedicine Protéines comprenant un fragment lair-1 muté et leurs utilisations
CN108291330A (zh) 2015-07-10 2018-07-17 西弗吉尼亚大学 卒中和卒中严重性的标志物
US10877045B2 (en) 2015-07-21 2020-12-29 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
CA2994416A1 (fr) 2015-08-04 2017-02-09 Cd Diagnostics, Inc. Procedes de detection d'une necrose liee a une reaction locale indesirable sur les tissus (altr)
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
WO2017031370A1 (fr) 2015-08-18 2017-02-23 The Broad Institute, Inc. Procédés et compositions permettant de changer la fonction et la structure de boucles et/ou de domaines de chromatine
JP6989927B2 (ja) 2015-08-25 2022-02-03 プロセナ バイオサイエンシーズ リミテッド リン酸化アルファ－シヌクレインを検出するための方法
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
WO2017040813A2 (fr) 2015-09-02 2017-03-09 University Of Massachusetts Détection de loci de gènes comprenant des répétitions matricielles de crispr et/ou des acides ribonucléiques mono-guides polychromatiques
WO2017044419A1 (fr) 2015-09-08 2017-03-16 University Of Massachusetts Activité dnase h de la protéine cas9 de neisseria meningitidis
EP3353547A1 (fr) 2015-09-22 2018-08-01 Delta TM Technologies Conception de systèmes tampons personnalisés spécifiques à une protéine
CN108368554B (zh) 2015-09-29 2022-09-09 Htg分子诊断有限公司 弥漫性大b细胞淋巴瘤(dlbcl)亚型分型的方法
WO2017059878A1 (fr) 2015-10-07 2017-04-13 Humabs Biomed Sa Anticorps neutralisant puissamment le virus de l'hépatite b et utilisations de ces derniers
SG11201802912PA (en) 2015-10-10 2018-05-30 Intrexon Corp Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
DK3362462T3 (da) 2015-10-12 2021-10-11 Advanced Cell Diagnostics Inc In situ-detektion af nukleotidvarianter i prøver med højt støjniveau, og sammensætninger og fremgangsmåder relateret dertil
CA3002740A1 (fr) 2015-10-19 2017-04-27 Dovetail Genomics, Llc Procedes d'assemblage de genomes, phasage d'haplotypes et detection d'acide nucleique independant cible
WO2017074703A1 (fr) 2015-10-29 2017-05-04 Siemens Healthcare Diagnostics Inc. Dosage en sandwich pour petites molécules
JP6987068B2 (ja) 2015-11-09 2021-12-22 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia 癌マーカーおよび治療標的としてのグリピカン２
HK1254843B (zh) 2015-11-20 2020-04-17 希杰生物科技株式会社 包含细菌菌株的组合物
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CN114470194A (zh) 2015-12-02 2022-05-13 斯特库伯株式会社 与btn1a1免疫特异性结合的抗体和分子及其治疗用途
KR102815803B1 (ko) 2015-12-02 2025-06-05 주식회사 에스티사이언스 당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체
SG11201804648RA (en) 2015-12-04 2018-06-28 Univ Texas Slc45a2 peptides for immunotherapy
PH12018501207B1 (en) 2015-12-21 2024-02-23 Novartis Ag Compositions and methods for decreasing tau expression
WO2017112492A2 (fr) 2015-12-22 2017-06-29 The Regents Of The University Of Colorado, A Body Corporate Protection d'arn de la dégradation à l'aide d'arn viraux modifiés
WO2017123685A1 (fr) 2016-01-13 2017-07-20 Medimmune, Llc Méthode de traitement de la grippe a
US10036011B2 (en) 2016-02-11 2018-07-31 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
EP3414338B1 (fr) 2016-02-11 2022-12-21 Qiagen Sciences, LLC Additifs polyphénoliques dans le séquençage par synthèse
WO2017147186A1 (fr) 2016-02-22 2017-08-31 Ursure, Inc. Système et méthode de détection d'agents thérapeutiques pour surveiller l'adhésion à un schéma thérapeutique
JP7441003B2 (ja) 2016-02-23 2024-02-29 ダブテイル ゲノミクス エルエルシー ゲノムアセンブリのためのフェージングされたリードセットの生成とハプロタイプフェージング
US20210120845A1 (en) 2016-02-25 2021-04-29 Dupont Nutrition Biosciences Aps Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
WO2017147561A1 (fr) 2016-02-26 2017-08-31 The Board Of Regents Of The University Of Texas System Anticorps se liant aux hémicanaux de la connexine (cx) 43 et leurs utilisations
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
SG10201913557TA (en) 2016-03-04 2020-02-27 4D Pharma Plc Compositions comprising bacterial blautia strains for treating visceral hypersensitivity
US10960013B2 (en) 2016-03-04 2021-03-30 East Carolina University J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
US10458995B2 (en) 2016-03-25 2019-10-29 Muralidhar Reddy Moola Combinatorial synthesis and biomarker development
KR102418372B1 (ko) 2016-03-29 2022-07-08 주식회사 에스티큐브 글리코실화된 pd-l1에 특이적인 이중 기능 항체 및 이의 사용 방법
US11046782B2 (en) 2016-03-30 2021-06-29 Musc Foundation For Research Development Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
CA3021914C (fr) 2016-04-27 2024-04-30 Gen-Probe Incorporated Reactif de lyse de cellules sanguines
WO2017194589A1 (fr) 2016-05-10 2017-11-16 Vib Vzw Inhibition du dysfonctionnement synaptique précoce à médiation par tau
WO2017197300A1 (fr) 2016-05-13 2017-11-16 Dovetail Genomics Llc Récupération d'informations de liaison de longue portée à partir d'échantillons conservés
EP3458483A1 (fr) 2016-05-16 2019-03-27 President and Fellows of Harvard College Couplage de biomolécule aqueuse sur des surfaces activées par plasma de co2
WO2017201731A1 (fr) 2016-05-27 2017-11-30 Beijing Vdjbio Co., Ltd. Anticorps, composition et kits les comprenant et leurs procédés d'utilisation
AU2017278261A1 (en) 2016-06-05 2019-01-31 Berg Llc Systems and methods for patient stratification and identification of potential biomarkers
EP3472193A4 (fr) 2016-06-20 2020-01-08 The Board of Trustees of the Leland Stanford Junior University Arn circulaires et leur utilisation dans l'immunomodulation
WO2018010789A1 (fr) 2016-07-13 2018-01-18 Humabs Biomed Sa Nouveaux anticorps se liant spécifiquement aux épitopes du virus zika et leurs utilisations
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
CA3031401A1 (fr) 2016-07-20 2018-01-25 Vib Vzw Agents de traitement des troubles neurologiques et psychiatriques
EP3487883B1 (fr) 2016-07-20 2023-01-04 Stcube, Inc. Méthodes de traitement et de thérapie du cancer utilisant une combinaison d'anticorps qui se lient à pd-l1 glycosylé
US10919904B2 (en) 2016-08-17 2021-02-16 North Carolina State University Northern-southern route to synthesis of bacteriochlorins
EP3534953A4 (fr) 2016-11-02 2020-10-07 Vanderbilt University Anticorps contre le virus zika humain et leurs procédés d'utilisation
US20180128828A1 (en) 2016-11-04 2018-05-10 James W. Stave Direct detection of microorganisms in patient samples by immunoassay
WO2018089231A1 (fr) 2016-11-09 2018-05-17 Qiagen Sciences Llc Mélanges photoprotecteurs utilisés comme réactifs d'imagerie dans le séquençage par synthèse
MX2021014356A (es) 2016-11-23 2022-11-24 Chemocentryx Inc Metodo para tratar glomeruloesclerosis segmentaria focal.
US20180150597A1 (en) 2016-11-29 2018-05-31 Genomic Vision Sa Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest
WO2018102252A1 (fr) 2016-11-30 2018-06-07 North Carolina State University Procédés de fabrication de macrocycles bactériochlorines comprenant un noyau isocyclique annelé et des composés apparentés
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
EP3574009A4 (fr) 2017-01-26 2020-11-25 Zlip Holding Limited Unité de liaison à l'antigène cd47 et ses utilisations
CA3049778C (fr) 2017-01-26 2024-06-18 Oklahoma Medical Research Foundation Biomarqueurs de l'activite, de l'intensite et de l'eruption de la maladie du lupus erythemateux dissemine
EP3576758A4 (fr) 2017-01-31 2020-12-09 Vanderbilt University Génération d'anticorps monoclonaux ige spécifiques d'allergènes et d'helminthes humains pour une utilisation diagnostique et thérapeutique
WO2018163051A1 (fr) 2017-03-06 2018-09-13 Novartis Ag Méthodes de traitement du cancer à expression d'ubb réduite
UA129243C2 (uk) 2017-04-19 2025-02-26 Інстітьют Фо Рісьорч Ін Біомедцін Антитіло, що зв'язується зі спорозоїтами p. falciparum
WO2018209126A1 (fr) 2017-05-10 2018-11-15 Rowan University Biomarqueurs de diagnostic pour la détection, le sous-typage et/ou l'évaluation de la progression de la sclérose en plaques
ES2877726T3 (es) 2017-05-22 2021-11-17 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
EP3630942B1 (fr) 2017-05-24 2022-11-30 4D Pharma Research Limited Compositions comprenant des souches bactériennes
KR20200015602A (ko) 2017-05-31 2020-02-12 주식회사 에스티큐브앤컴퍼니 Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도
US12215151B2 (en) 2017-05-31 2025-02-04 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that immunospecifically bind to BTN1A1
CN110997724A (zh) 2017-06-06 2020-04-10 斯特库伯株式会社 使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法
ES2841902T3 (es) 2017-06-14 2021-07-12 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
TWI812624B (zh) 2017-06-14 2023-08-21 南韓商希杰生物科技股份有限公司 包含細菌品系之組成物
PL3600363T3 (pl) 2017-06-14 2021-06-14 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
US10768185B2 (en) 2017-07-20 2020-09-08 Trustees Of Boston University Tenofovir detection assay
US11530413B2 (en) 2017-07-21 2022-12-20 Novartis Ag Compositions and methods to treat cancer
EP3672990A1 (fr) 2017-08-25 2020-07-01 Five Prime Therapeutics, Inc. Anticorps anti-b7-h4 et leurs procédés d'utilisation
WO2019042555A1 (fr) 2017-08-31 2019-03-07 Humabs Biomed Sa Anticorps multispécifiques se liant spécifiquement aux épitopes du virus zika et leurs utilisations
KR102678252B1 (ko) 2017-09-01 2024-06-26 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 재조합 이중특이적 항체
AU2018324070B2 (en) 2017-09-01 2023-05-18 East Carolina University Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response
SG11202001535RA (en) 2017-09-05 2020-03-30 Gladiator Biosciences Inc Method of targeting exosomes
US11464784B2 (en) 2017-09-15 2022-10-11 The Regents Of The University Of California Inhibition of aminocylase 3 (AA3) in the treatment of cancer
CN111868039A (zh) 2017-09-26 2020-10-30 加利福尼亚大学董事会 用于治疗癌症的组合物和方法
EP3692152B1 (fr) 2017-10-04 2025-09-03 The Broad Institute, Inc. Procédés et compositions permettant de modifier la fonction et la structure de boucles et/ou de domaines de chromatine
AU2018347361A1 (en) 2017-10-11 2020-04-30 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with CCR2 antagonists
WO2019075097A1 (fr) 2017-10-11 2019-04-18 Board Of Regents, The University Of Texas System Anticorps pd-l1 humains et leurs procédés d'utilisation
CN119930795A (zh) 2017-10-12 2025-05-06 得克萨斯大学体系董事会 用于免疫疗法的t细胞受体
EP3706795A4 (fr) 2017-11-09 2021-10-13 Pinteon Therapeutics Inc. Méthodes et compositions pour la génération et l'utilisation d'anticorps tau phosphorylés spécifiques à une conformation humanisée
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
CA3085324A1 (fr) 2017-12-15 2019-06-20 Syngenta Participations Ag Ligands non-anticorps pour la detection de proteines cibles
EP3735589A2 (fr) 2018-01-05 2020-11-11 Vanderbilt University Neutralisation à médiation par anticorps du virus chikungunya
WO2019152543A1 (fr) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Préparation d'échantillon pour récupération de liaison d'adn
WO2019155041A1 (fr) 2018-02-12 2019-08-15 Vib Vzw ANTICORPS COMPLEXES Gβγ ET LEURS UTILISATIONS
JP2021514379A (ja) 2018-02-21 2021-06-10 ファイブ プライム セラピューティクス， インコーポレイテッド Ｂ７−ｈ４抗体製剤
US20200408771A1 (en) 2018-02-22 2020-12-31 The United States Of America,As Represented By The Secretary,Department Of Health And Human Services Cd153 and/or cd30 in infection
MA52416A (fr) 2018-03-02 2021-04-21 Five Prime Therapeutics Inc Anticorps b7-h4 et leurs procédés d'utilisation
EP3765031A4 (fr) 2018-03-14 2022-03-23 Memorial Sloan Kettering Cancer Center Anticorps anti-acide polysialique et leurs utilisations
WO2019182867A1 (fr) 2018-03-23 2019-09-26 Board Of Regents, The University Of Texas System Anticorps à double spécificité pour pd-l1 et pd-l2 humains et leurs procédés d'utilisation
EP3768726B1 (fr) 2018-03-23 2024-10-30 Board of Regents, The University of Texas System Anticorps à double spécificité pour pd-l1 et pd-l2 et leurs procédés d'utilisation
WO2019199643A1 (fr) 2018-04-09 2019-10-17 Bio-Techne Corporation Procédés d'amélioration supplémentaire de l'amplification de signal pour la détection in situ d'acides nucléiques
JP7328324B2 (ja) 2018-04-24 2023-08-16 アンプソース・バイオファーマ・シャンハイ・インコーポレイテッド Ｔｉｍ－３に対する抗体およびその使用
EP3788138A1 (fr) 2018-05-02 2021-03-10 Novartis AG Régulateurs de cellules souches pluripotentes humaines et leurs utilisations
TW202016144A (zh) 2018-06-21 2020-05-01 日商第一三共股份有限公司 包括cd3抗原結合片段之組成物及其用途
WO2020056077A1 (fr) 2018-09-13 2020-03-19 The Board Of Regents Of The University Of Texas System Nouveaux anticorps anti-lilrb4 et leurs utilisations
EP3856753A4 (fr) 2018-09-28 2022-11-16 Centrillion Technology Holdings Corporation Terminateurs réversibles à liaison disulfure
BR112021007123A2 (pt) 2018-10-15 2021-08-10 University Of Massachusetts edição de base de dna programável pelas proteínas de fusão nme2cas9-desaminase
JP7248788B2 (ja) 2018-10-18 2023-03-29 オクラホマ メディカル リサーチ ファウンデーション 疾患活動性を特徴付ける全身性エリテマトーデス（ｓｌｅ）疾患活動性免疫指標のバイオマーカー
US12510539B2 (en) 2018-10-18 2025-12-30 Progentec Diagnostics, Inc. Biomarkers for a systemic lupus erythematosus (SLE) disease activity immune index that characterizes disease activity
BR112021007690A2 (pt) 2018-10-22 2021-08-10 Shanghai GenBase Biotechnology Co., Ltd. anticorpo anti-cldn18.2 e uso do mesmo
EP3870614A1 (fr) 2018-10-23 2021-09-01 GlyCardial Diagnostics, S.L. Anticorps spécifiques de l'apoj glycosylée et leurs utilisations
KR20210124179A (ko) 2018-11-02 2021-10-14 베이징 브이디제이바이오 컴퍼니 리미티드 변형된 ctla4 및 이의 사용 방법
EP3881072A4 (fr) 2018-11-16 2022-11-09 President And Fellows Of Harvard College Molécules et procédés d'immunodétection améliorée de petites molécules, telles que l'histamine
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
JP7478149B2 (ja) 2018-11-28 2024-05-02 オレゴン ヘルス アンド サイエンス ユニバーシティー 治療用第ｘｉｉ因子抗体
JP7462632B2 (ja) 2018-11-30 2024-04-05 カリス エムピーアイ インコーポレイテッド 次世代分子プロファイリング
MX2021006756A (es) 2018-12-19 2021-09-28 Humabs Biomed Sa Anticuerpos que neutralizan el virus de la hepatitis b y usos de los mismos.
US12297265B2 (en) 2018-12-28 2025-05-13 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Antibody and use thereof
WO2020185312A2 (fr) 2019-01-25 2020-09-17 President And Fellows Of Harvard College Compositions et procédé de synthèse d'acides nucléiques
US12571028B2 (en) 2019-02-15 2026-03-10 Advanced Cell Diagnostics, Inc. Methods for multiplex detection of nucleic acids by in situ hybridization
EP3938400B1 (fr) 2019-03-11 2025-07-30 Memorial Sloan Kettering Cancer Center Anticorps cd22 et leurs procédés d'utilisation
US10745492B1 (en) 2019-04-03 2020-08-18 Ark Diagnostics, Inc. Antibodies to symmetrically dimethylated arginine analytes and use thereof
JP7650807B2 (ja) 2019-04-16 2025-03-25 シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド 抗ＦＸＩ／ＦＸＩａ抗体及びその使用
WO2020223576A1 (fr) 2019-04-30 2020-11-05 Chondrial Therapeutics, Inc. Marqueurs sensibles à la frataxine pour déterminer l'efficacité d'une thérapie de remplacement de frataxine
EP3959292B1 (fr) 2019-05-20 2025-07-02 NIRvana Sciences Inc. Colorants à émission étroite, compositions contenant ces derniers, et méthodes de production et d'utilisation correspondantes
US20220249707A1 (en) 2019-05-20 2022-08-11 Nirvana Sciences Inc. Narrow emission dyes, compositions comprising same, and methods for making and using same
CA3140406A1 (fr) 2019-05-28 2020-12-03 Shanghaitech University Composition et methodes pour le traitement d'une dysplasie ectodermique 2, type clouston
US20220257790A1 (en) 2019-06-26 2022-08-18 Biorchestra Co., Ltd. Micellar nanoparticles and uses thereof
WO2020264185A1 (fr) 2019-06-27 2020-12-30 Dovetail Genomics, Llc Procédés et compositions pour ligature de proximité
CN120484131A (zh) 2019-07-19 2025-08-15 费城儿童医院 包含磷脂酰肌醇蛋白聚糖2结合结构域的嵌合抗原受体
JP7644087B2 (ja) 2019-07-26 2025-03-11 ヴァンダービルト ユニバーシティ エンテロウイルスｄ６８に対するヒトモノクローナル抗体
US20210048436A1 (en) 2019-08-15 2021-02-18 Psychemedics Corporation Homogeneous enzyme immunoassay for keratinized structures
KR20220063188A (ko) 2019-08-29 2022-05-17 비르 바이오테크놀로지, 인코포레이티드 B형 간염 바이러스 감염을 치료하기 위한 항체 조성물 및 방법
CA3151317A1 (fr) 2019-09-16 2021-03-25 Patrick J. GROHAR Compositions et methodes pour le traitement de tumeurs mutantes swi-snf
JP2023501871A (ja) 2019-09-20 2023-01-20 上海吉倍生物技術有限公司 Ｂｃｍａ標的化抗体及びキメラ抗原受容体
CN114729045B (zh) 2019-09-26 2025-09-09 斯特库比公司 对糖基化的ctla-4特异性的抗体及其使用方法
WO2021063201A1 (fr) 2019-09-30 2021-04-08 四川科伦博泰生物医药股份有限公司 Anticorps anti-pd-1 et son utilisation
US12595304B2 (en) 2019-10-09 2026-04-07 Stcube & Co., Inc. Antibodies specific to glycosylated LAG3 and methods of use thereof
US12590950B2 (en) 2019-10-11 2026-03-31 University Of Massachusetts Methods for predicting ER-mediated DNA damage
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
WO2021112918A1 (fr) 2019-12-02 2021-06-10 Caris Mpi, Inc. Prédicteur de réponse au platine dans une approche pan-cancer
CN112898414B (zh) 2019-12-04 2024-05-10 珠海泰诺麦博制药股份有限公司 抗人巨细胞病毒抗体及其用途
CN115176027A (zh) 2019-12-12 2022-10-11 哈佛大学校长及研究员协会 用于光指导的生物分子条形码化的组合物和方法
MX2022004919A (es) 2019-12-13 2022-05-16 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Anticuerpo anti-linfopoyetina estromal timica (tslp) y sus usos.
CA3164996A1 (fr) 2019-12-20 2021-06-14 Novarock Biotherapeutics, Ltd. Anticorps anti-interleukine-23 p19 et leurs methodes d'utilisation
EP3842452A1 (fr) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Protéines d'échafaudage et nanoconjugués thérapeutiques à base de nidogène
CN113061165B (zh) 2020-01-02 2026-04-21 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
WO2021156490A2 (fr) 2020-02-06 2021-08-12 Vib Vzw Liants du coronavirus
US20210277092A1 (en) 2020-02-11 2021-09-09 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)
WO2021167908A1 (fr) 2020-02-17 2021-08-26 Board Of Regents, The University Of Texas System Procédés d'expansion de lymphocytes infiltrant les tumeurs et leur utilisation
KR20230012464A (ko) 2020-02-25 2023-01-26 브이아이비 브이지더블유 류신-풍부 반복 키나제 2 알로스테릭 조절제
EP4110823A1 (fr) 2020-02-26 2023-01-04 A2 Biotherapeutics, Inc. Polypeptides ciblant des complexes mage-a3 peptide-mhc et leurs méthodes d'utilisation
FI4045533T3 (fi) 2020-03-26 2024-02-02 Univ Vanderbilt Ihmisen monoklonaalisia vasta-aineita vakavalle akuutille koronavirus 2 -hengityselinoireyhtymälle (sars-cov-2)
WO2021195385A1 (fr) 2020-03-26 2021-09-30 Vanderbilt University Anticorps monoclonaux humains dirigés contre le coronavirus du syndrome respiratoire aigu sévère 2 (sras-cov-2)
TWI904146B (zh) 2020-03-31 2025-11-11 美商卡默森屈有限公司 使用ｃｃｒ９抑制劑及抗ｉｌ-２３阻斷抗體治療發炎性腸道疾病的組成物及方法
WO2021207062A1 (fr) 2020-04-07 2021-10-14 Advanced Cell Diagnostics, Inc. Procédé de détection d'acides nucléiques cibles par hybridation in situ , et kit associé
US20230203567A1 (en) 2020-04-22 2023-06-29 President And Fellows Of Harvard College Isothermal methods, compositions, kits, and systems for detecting nucleic acids
IL298184A (en) 2020-05-15 2023-01-01 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Antibody drug conjugate, preparation method therefor and use thereof
CA3182458A1 (fr) 2020-06-24 2021-12-30 Laura ROSEN Anticorps neutralisants modifies contre le virus de l'hepatite b et utilisations associees
EP3939999A1 (fr) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Anticorps neutralisant la sous-unité alpha du récepteur de l'interleukine 11 (il11ra) et leurs utilisations
EP4200440A4 (fr) 2020-08-21 2024-10-09 Advanced Cell Diagnostics, Inc. Compositions et procédés pour déterminer une clonalité de lymphocytes t
WO2022047359A1 (fr) 2020-08-31 2022-03-03 Berg Llc Biomarqueurs protéiques du cancer du pancréas
US20230331867A1 (en) 2020-09-04 2023-10-19 Novarock Biotherapeutics, Ltd. Nectin-4 antibodies and uses thereof
NZ798475A (en) 2020-10-09 2026-03-27 Univ Texas Prefusion-stabilized hmpv f proteins
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
US12492372B2 (en) 2020-11-24 2025-12-09 Monash University Induced stem cells
EP4255451A4 (fr) 2020-12-03 2025-01-01 The Board Of Regents Of The University Of Texas System Méthodes d'identification d'anticorps bloquant lilrb
WO2022120378A1 (fr) 2020-12-04 2022-06-09 University Of Tennessee Research Foundation Procédé de diagnostic de maladies amyloïdes
WO2022143743A1 (fr) 2020-12-31 2022-07-07 和铂医药(苏州)有限公司 Protéine liant un antigène lifr humain, son procédé de préparation et son utilisation
JP2024504167A (ja) 2021-01-26 2024-01-30 ヴィア・バイオテクノロジー・インコーポレイテッド Ｂ型肝炎ウイルス感染を処置するための抗体組成物および方法
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
MX2023008895A (es) 2021-02-09 2023-08-09 Medilink Therapeutics Suzhou Co Ltd Conjugado de sustancia bioactiva, metodo de preparacion y uso del mismo.
US20250263490A1 (en) 2021-02-19 2025-08-21 Vib Vzw Cation-Independent Mannose-6-Phosphate Receptor Binders
CA3212530A1 (fr) 2021-03-05 2022-09-09 Shanghai GenBase Biotechnology Co., Ltd. Anticorps anti-cldn6 et son utilisation
TW202302155A (zh) 2021-03-08 2023-01-16 美商伊繆諾金公司 用於增加靶向ａｄａｍ９之免疫結合物治療癌症之功效的方法
JP2024508597A (ja) 2021-03-09 2024-02-28 四川科倫博泰生物医薬股▲フン▼有限公司 Ｒｏｒ１結合タンパク質及びその用途
CA3172265A1 (fr) 2021-03-10 2022-09-15 Dimitri BIELI Anticorps diriges contre la tdp-43 et methodes d'utilisation de ceux-ci
WO2022216841A1 (fr) 2021-04-06 2022-10-13 Berg Llc Marqueurs protéiques pour un cancer du sein positif au récepteur des œstrogènes (er) de type luminal a (la) et de type luminal b1 (lb1)
EP4320441A1 (fr) 2021-04-06 2024-02-14 BPGbio, Inc. Marqueurs protéiques pour le cancer du sein du type positif aux récepteurs des oestrogènes (er) et du type négatif aux récepteurs des oestrogènes (er)
EP4320443A1 (fr) 2021-04-06 2024-02-14 BPGbio, Inc. Marqueurs protéiques pour le pronostic de la progression du cancer du sein
EP4322837A4 (fr) 2021-04-16 2025-02-26 Advanced Cell Diagnostics, Inc. Matériaux et procédés se rapportant au traitement d'images
CA3215979A1 (fr) 2021-04-19 2022-10-27 Ghassan SAED Methodes de detection ou de traitement de troubles hyperproliferatifs de l'endometre et de l'ovaire
CA3223081A1 (fr) 2021-07-15 2023-01-19 Samir Mitragotri Compositions et methodes associees a des cellules comprenant des particules adherees
CA3228014A1 (fr) 2021-07-30 2023-02-16 Vib Vzm Liants du recepteur mannose-6-phosphate independants des cations pour la degradation ciblee de proteines
JP2024536133A (ja) 2021-09-29 2024-10-04 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 抗ｈｓｐ７０抗体およびその治療的使用
EP4426821A1 (fr) 2021-11-02 2024-09-11 University of Massachusetts Protéines de fusion à domaine nme2cas9 incrusté
PE20241755A1 (es) 2021-11-19 2024-08-28 Mirobio Ltd Anticuerpos pd-1 disenados por ingenieria y usos de estos
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
MX2024009174A (es) 2022-01-25 2024-08-09 Medilink Therapeutics Suzhou Co Ltd Anticuerpo contra her3, conjugado y uso del mismo.
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
EP4238988A1 (fr) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Anticorps dirigés contre le sars-cov-2 et leurs utilisations
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
TW202405011A (zh) 2022-04-01 2024-02-01 美國德州系統大學評議委員會 針對人類pd-l1及pd-l2之雙重特異性抗體及其使用方法
EP4505182A1 (fr) 2022-04-06 2025-02-12 Larimar Therapeutics, Inc. Marqueurs sensibles à la frataxine pour surveiller une thérapie de remplacement de frataxine
PE20251170A1 (es) 2022-04-06 2025-04-23 Mirobio Ltd Anticuerpos cd200r disenados por ingenieria y usos de estos
JP2025519540A (ja) 2022-06-08 2025-06-26 オンキュアー，インコーポレイテッド Ｐｉ３ｋ阻害剤としてのベンゾピリミジン－４（３ｈ）－オン
WO2023240201A1 (fr) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Marqueurs sensibles à la frataxine pour surveiller la progression et le traitement du syndrome de leigh
WO2023239940A1 (fr) 2022-06-10 2023-12-14 Research Development Foundation Variants de fc igg1 sélectifs de fcriib modifiés et leurs utilisations
KR20250028265A (ko) 2022-06-20 2025-02-28 쓰추안 휘위 파머슈티컬 컴퍼니., 리미티드. 항체 및 이의 용도
AU2023307126A1 (en) 2022-07-14 2025-02-13 Medilink Therapeutics (Suzhou) Co., Ltd. Antibody-drug conjugate, and preparation method therefor and use thereof
WO2024028794A1 (fr) 2022-08-02 2024-02-08 Temple Therapeutics BV Méthodes de traitement de troubles de l'endomètre et de l'hyperprolifération ovarienne
EP4573553A1 (fr) 2022-08-15 2025-06-25 ABSCI Corporation Enrichissement de cellule spécifique à une activité d'affinité quantitative
WO2024038160A1 (fr) 2022-08-18 2024-02-22 Vib Vzw Moyens et méthodes pour moduler l'excitabilité neuronale
WO2024054469A1 (fr) 2022-09-08 2024-03-14 Onkure, Inc. Isoquinolones utilisés en tant qu'inhibiteurs de pi3k
WO2024064024A1 (fr) 2022-09-19 2024-03-28 Onkure, Inc. Dérivés de ((4-oxo-3,4-dihydroquinazolin-8-yl)méthyl)amine utilisés en tant qu'inhibiteurs de p13k pour le traitement du cancer
WO2024064002A1 (fr) 2022-09-20 2024-03-28 Onkure, Inc. Inhibiteur de hdac oki-179 destiné au traitement de cancers résultant d'une mutation de la voie mapk
WO2024068744A1 (fr) 2022-09-27 2024-04-04 Vib Vzw Antiviraux dirigés contre le virus parainfluenza humain
WO2024081345A1 (fr) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones utilisées en tant qu'inhibiteurs de pi3k
KR20250114034A (ko) 2022-11-11 2025-07-28 아이간 바이오사이언스 Iga 프로테아제 폴리펩타이드 제제
WO2024124041A1 (fr) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Détection multiplexée de cibles d'acides nucléiques
EP4648796A2 (fr) 2023-01-09 2025-11-19 Board of Regents, The University of Texas System Protéines du virus parainfluenza humain 3f stabilisées dans la préfusion
CN120769910A (zh) 2023-02-23 2025-10-10 罗切斯特大学 用于制备封闭端dna线分子的药剂和方法
WO2024213640A1 (fr) 2023-04-11 2024-10-17 Sterling Ip Pte. Ltd. Inhibition de : résistance générée au traitement de stroma et/ou stroma/diaphonie de cellules cancéreuses
EP4727971A1 (fr) 2023-06-13 2026-04-22 Adcentrx Therapeutics Inc. Méthodes et compositions associées à des anticorps et conjugués anticorps-médicament (adcs) qui se lient à des protéines de nectine-4
WO2024261344A1 (fr) 2023-06-23 2024-12-26 Vib Vzw Nouveaux liants ciblant le pathogène résistant aux médicaments multiples acinetobacter baumannii
WO2025031446A1 (fr) 2023-08-09 2025-02-13 厦门大学 Polypeptide setdb1 citrulliné et son utilisation dans le diagnostic de la polyarthrite rhumatoïde
AU2024325407A1 (en) 2023-08-11 2026-02-19 Onkure Therapeutics, Inc. Benzopyridinones and benzopyrimidinones as pi3k inhibitors
AU2024339036A1 (en) 2023-09-07 2026-03-12 University Of Tennessee Research Foundation Method for diagnosing amyloid diseases
WO2025079025A1 (fr) 2023-10-13 2025-04-17 Takeda Pharmaceutical Company Limited Conjugué ides-rapamycine dans une thérapie génique aav
WO2025125577A1 (fr) 2023-12-14 2025-06-19 Vib Vzw Anticorps dirigés contre le virus de la grippe b
WO2025155991A2 (fr) 2024-01-19 2025-07-24 Bpgbio, Inc. Biomarqueurs prédictifs pour la réponse à un traitement par coenzyme q10 dans le cadre d'un cancer du pancréas
WO2025202871A1 (fr) 2024-03-27 2025-10-02 Pfizer Inc. Procédés d'identification de biomarqueurs de réponse à un traitement et leur utilisation avec un inhibiteur de cdk4
WO2025207755A1 (fr) 2024-03-29 2025-10-02 Onkure, Inc. Quinolizinones utilisés en tant qu'inhibiteurs de pi3k
WO2025212360A1 (fr) 2024-04-01 2025-10-09 Onkure, Inc. Isoquinolones en tant qu'inhibiteurs de pi3k
WO2025255233A1 (fr) 2024-06-07 2025-12-11 Onkure, Inc. Composés contenant des noyaux tricycliques fusionnés utilisés en tant qu'inhibiteurs de pi3k
WO2025264533A1 (fr) 2024-06-17 2025-12-26 Adcentrx Therapeutics Inc. Procédés et compositions associés à des conjugués anticorps-médicament (adcs) qui se lient à des protéines steap-1
WO2026006151A2 (fr) 2024-06-24 2026-01-02 University Of Rochester Fonctionnalisation d'ace-arnt codant pour des picovecteurs linéaires synthétiques
WO2026008664A1 (fr) 2024-07-01 2026-01-08 Vib Vzw Modulateurs allostériques de complexes de récepteurs immunitaires inhibiteurs
WO2026019976A1 (fr) 2024-07-17 2026-01-22 The Broad Institute, Inc. Agent de réticulation covalent universel pour conjugués anticorps-oligo
WO2026020031A2 (fr) 2024-07-18 2026-01-22 Novarock Biotherapeutics, Ltd. Anticorps cdh17 et leurs utilisations
WO2026044000A1 (fr) 2024-08-20 2026-02-26 Ethyreal Bio, Inc. Anticorps multispécifiques et leurs méthodes d'utilisation
WO2026044153A1 (fr) 2024-08-21 2026-02-26 Bpgbio, Inc. Utilisation de biomarqueurs dans le diagnostic du cancer du pancréas

Also Published As

Publication number Publication date
US3817837A (en) 1974-06-18

Similar Documents

Publication Publication Date Title
BE846194Q (fr) Dosage par amplification enzymatique
NL155939C (nl) Luchtbehandelingsinstallatie.
NL169239C (nl) Stroomversterker.
SE7506821L (sv) Fenylalaninderivat.
NL166589C (nl) Versterkerketen.
NL169005C (nl) Versterkerketen.
BE772636A (fr) Enzymes
FI45714C (fi) Kylvökone.
OA04164A (fr) Complexes enzyme-polimère.
NL170579C (nl) Versterkerketen.
TR17083A (tr) Koemuerue gaziastirma tesisi
AT312687B (de) Leitungsverstärker
BE767978A (fr) Jardiniere
SE381149B (sv) Transistorforsterkare
BE771834A (fr) Enzymes
AT323109B (de) Enzymatische analysen
AT313453B (de) Saugzugverstärker
SE380589B (sv) Fluidistorforsterkare
FI51658C (fi) Desintegraattori.
SE387739B (sv) Hydraulisk vag
BE775067A (fr) Amplificateur
AT315027B (de) Schießscheibe
BR7105463D0 (pt) Novo fertilizante concentrado
BE768324A (fr) Articulator.
ES155123Y (es) Brida graduable.

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: SYVA CY

Effective date: 19940618

RE20 Patent expired

Owner name: SYVA CY

Effective date: 19960914