BE886319A - A-oxo-1h-thiazolo-(3,2-a)-pyrimidine-2-carboxamides, anti-allergiques et anti-ulcereux, medicament les contenant et composes intermediaires permettant de les obtenir - Google Patents

A-oxo-1h-thiazolo-(3,2-a)-pyrimidine-2-carboxamides, anti-allergiques et anti-ulcereux, medicament les contenant et composes intermediaires permettant de les obtenir

Info

Publication number: BE886319A
Authority: BE; Belgium
Prior art keywords: thiazolo; carboxamides; ulcer; allergic; pyrimidine
Prior art date: 1979-11-23

Application number

BE0/202915A

Other languages

English (en)

French (fr)

Inventor

S Kadin

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-11-23

Filing date

1980-11-24

Publication date

1981-05-25

1980-11-24 Application filed by Pfizer filed Critical Pfizer

1981-05-25 Publication of BE886319A publication Critical patent/BE886319A/fr

Links

230000003266 anti-allergic effect Effects 0.000 title 1
230000000767 anti-ulcer Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Thiazole And Isothizaole Compounds (AREA)

BE0/202915A 1979-11-23 1980-11-24 A-oxo-1h-thiazolo-(3,2-a)-pyrimidine-2-carboxamides, anti-allergiques et anti-ulcereux, medicament les contenant et composes intermediaires permettant de les obtenir BE886319A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US9663179A	1979-11-23	1979-11-23

Publications (1)

Publication Number	Publication Date
BE886319A true BE886319A (fr)	1981-05-25

Family

ID=22258306

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE0/202915A BE886319A (fr)	1979-11-23	1980-11-24	A-oxo-1h-thiazolo-(3,2-a)-pyrimidine-2-carboxamides, anti-allergiques et anti-ulcereux, medicament les contenant et composes intermediaires permettant de les obtenir

Country Status (35)

Country	Link
JP (1)	JPS5687586A (cs)
KR (1)	KR830004322A (cs)
AR (2)	AR228859A1 (cs)
AT (1)	AT380883B (cs)
AU (1)	AU520995B2 (cs)
BE (1)	BE886319A (cs)
CA (1)	CA1143731A (cs)
CH (1)	CH649299A5 (cs)
CS (1)	CS241476B2 (cs)
DD (1)	DD154608A5 (cs)
DE (2)	DE3043979C2 (cs)
DK (1)	DK151811C (cs)
EG (1)	EG14929A (cs)
ES (1)	ES8203363A1 (cs)
FI (1)	FI67706C (cs)
FR (1)	FR2470132A1 (cs)
GB (1)	GB2063862B (cs)
GR (1)	GR72132B (cs)
GT (1)	GT198066458A (cs)
HU (1)	HU179091B (cs)
IE (1)	IE50404B1 (cs)
IL (1)	IL61535A (cs)
IN (1)	IN154926B (cs)
IT (1)	IT1209373B (cs)
LU (1)	LU82950A1 (cs)
NL (1)	NL182565C (cs)
NO (1)	NO803521L (cs)
NZ (1)	NZ195596A (cs)
PH (1)	PH16666A (cs)
PL (1)	PL132354B1 (cs)
PT (1)	PT72090B (cs)
SE (1)	SE448732B (cs)
SU (1)	SU1042620A3 (cs)
YU (1)	YU41953B (cs)
ZA (1)	ZA807293B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8300728D0 (en) *	1983-01-12	1983-02-16	Erba Farmitalia	Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) *	1983-07-22	1984-07-03	Bristol-Myers Company	Anti-ulcer agents
GB8422916D0 (en) *	1984-09-11	1984-10-17	May & Baker Ltd	Compositions of matter
JP2690742B2 (ja) *	1987-03-30	1997-12-17	第一製薬株式会社	複素環アミン誘導体
DE68926473T2 (de) *	1988-03-28	1996-10-02	Janssen Pharmaceutica Nv	Mittel zur Konservierung oder Wiederherstellung der gesunden Haut
TWI500623B (zh) *	2009-10-13	2015-09-21	Torrent Pharmaceuticals Ltd	新穎稠合噻唑及噁唑嘧啶酮

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1331059A (en) *	1971-04-19	1973-09-19	Lilly Industries Ltd	Pyrimidotriazinone compounds
US4041163A (en) *	1976-03-29	1977-08-09	Pfizer Inc.	N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents
DE2810863A1 (de) *	1978-03-13	1979-09-27	Boehringer Mannheim Gmbh	1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
US4223031A (en) *	1978-05-05	1980-09-16	Mead Johnson & Company	Azolopyrimidinones

1980
- 1980-09-30 DK DK413180A patent/DK151811C/da not_active IP Right Cessation
- 1980-10-15 IN IN760/DEL/80A patent/IN154926B/en unknown
- 1980-11-17 SU SU803212053A patent/SU1042620A3/ru active
- 1980-11-18 AR AR283276A patent/AR228859A1/es active
- 1980-11-18 GB GB8036904A patent/GB2063862B/en not_active Expired
- 1980-11-18 CS CS807820A patent/CS241476B2/cs unknown
- 1980-11-18 HU HU80802755A patent/HU179091B/hu not_active IP Right Cessation
- 1980-11-19 EG EG723/80A patent/EG14929A/xx active
- 1980-11-19 CH CH8567/80A patent/CH649299A5/fr not_active IP Right Cessation
- 1980-11-20 GR GR63413A patent/GR72132B/el unknown
- 1980-11-20 YU YU2950/80A patent/YU41953B/xx unknown
- 1980-11-20 NZ NZ195596A patent/NZ195596A/en unknown
- 1980-11-21 FR FR8024822A patent/FR2470132A1/fr active Granted
- 1980-11-21 IT IT8026176A patent/IT1209373B/it active
- 1980-11-21 NO NO803521A patent/NO803521L/no unknown
- 1980-11-21 ES ES497066A patent/ES8203363A1/es not_active Expired
- 1980-11-21 CA CA000365258A patent/CA1143731A/en not_active Expired
- 1980-11-21 SE SE8008189A patent/SE448732B/sv not_active IP Right Cessation
- 1980-11-21 IE IE2418/80A patent/IE50404B1/en unknown
- 1980-11-21 FI FI803628A patent/FI67706C/fi not_active IP Right Cessation
- 1980-11-21 NL NLAANVRAGE8006362,A patent/NL182565C/xx not_active IP Right Cessation
- 1980-11-21 DE DE3043979A patent/DE3043979C2/de not_active Expired
- 1980-11-21 IL IL61535A patent/IL61535A/xx unknown
- 1980-11-21 LU LU82950A patent/LU82950A1/fr unknown
- 1980-11-21 JP JP16450280A patent/JPS5687586A/ja active Granted
- 1980-11-21 ZA ZA00807293A patent/ZA807293B/xx unknown
- 1980-11-21 DE DE3050491A patent/DE3050491C2/de not_active Expired
- 1980-11-21 PT PT72090A patent/PT72090B/pt not_active IP Right Cessation
- 1980-11-21 AU AU64595/80A patent/AU520995B2/en not_active Ceased
- 1980-11-21 AT AT0570780A patent/AT380883B/de not_active IP Right Cessation
- 1980-11-21 PH PH24891A patent/PH16666A/en unknown
- 1980-11-21 GT GT198066458A patent/GT198066458A/es unknown
- 1980-11-21 DD DD80225391A patent/DD154608A5/de not_active IP Right Cessation
- 1980-11-22 KR KR1019800004474A patent/KR830004322A/ko not_active Ceased
- 1980-11-22 PL PL1980228008A patent/PL132354B1/pl unknown
- 1980-11-24 BE BE0/202915A patent/BE886319A/fr not_active IP Right Cessation
1982
- 1982-09-13 AR AR290628A patent/AR231296A1/es active

Also Published As

Publication number	Publication date
PT72090A (en)	1980-12-01
FI67706B (fi)	1985-01-31
FR2470132A1 (fr)	1981-05-29
DE3043979A1 (de)	1981-09-03
PL132354B1 (en)	1985-02-28
ZA807293B (en)	1981-12-30
PL228008A1 (cs)	1981-12-11
IL61535A (en)	1984-06-29
IE50404B1 (en)	1986-04-16
CH649299A5 (fr)	1985-05-15
DK413180A (da)	1981-05-24
FI803628L (fi)	1981-05-24
AR231296A1 (es)	1984-10-31
DK151811B (da)	1988-01-04
NL8006362A (nl)	1981-06-16
CS782080A2 (en)	1985-06-13
DD154608A5 (de)	1982-04-07
GT198066458A (es)	1982-05-15
CA1143731A (en)	1983-03-29
AT380883B (de)	1986-07-25
NO803521L (no)	1981-05-25
GR72132B (cs)	1983-09-19
IN154926B (cs)	1984-12-22
SE448732B (sv)	1987-03-16
KR830004322A (ko)	1983-07-09
SU1042620A3 (ru)	1983-09-15
IT8026176A0 (it)	1980-11-21
HU179091B (en)	1982-08-28
FI67706C (fi)	1985-05-10
YU41953B (en)	1988-02-29
AR228859A1 (es)	1983-04-29
SE8008189L (sv)	1981-05-24
PT72090B (en)	1981-09-29
LU82950A1 (fr)	1981-06-04
ES497066A0 (es)	1982-04-01
IT1209373B (it)	1989-07-16
GB2063862A (en)	1981-06-10
GB2063862B (en)	1983-06-22
IE802418L (en)	1981-05-23
DE3050491C2 (de)	1985-10-10
YU295080A (en)	1983-06-30
NL182565C (nl)	1988-04-05
PH16666A (en)	1983-12-13
CS241476B2 (en)	1986-03-13
ATA570780A (de)	1985-12-15
EG14929A (en)	1989-01-30
IL61535A0 (en)	1980-12-31
JPS617432B2 (cs)	1986-03-06
FR2470132B1 (cs)	1983-07-29
AU6459580A (en)	1981-05-28
ES8203363A1 (es)	1982-04-01
DE3043979C2 (de)	1986-08-21
NZ195596A (en)	1984-05-31
AU520995B2 (en)	1982-03-11
NL182565B (nl)	1987-11-02
DK151811C (da)	1988-06-06
JPS5687586A (en)	1981-07-16

Legal Events

Date

Code

Title

Description

1990-05-31

RE

Patent lapsed

Owner name: PFIZER INC.

Effective date: 19891130

Publication	Publication Date	Title
MA19048A1 (fr)	1981-10-01	Imidazo [1,2-a] pyridine,procedes pour leur preparation et composition pharmaceutiques les contenant .
PT77488B (fr)	1986-05-07	Procede de preparation de derives de phenyl-1-piperidino-2-propanol et de compositions pharmaceutiques les contenant
BE884077A (fr)	1980-12-29	Nouveaux tetra- et pentapeptides, leur preparation et les medicaments qui les contiennent
BE862107A (fr)	1978-06-21	Nouveaux derives de 1,4-dihydropyridine substitues en position 2, leur procede de preparation et medicament les contenant
BE894175A (fr)	1983-02-23	Nouvelles imidazotetrazinones, leur preparation et les medicaments qui les contiennent.
BE865015A (fr)	1978-09-18	Pseudotrisaccharides, leur procede de preparation et medicament les contenant
FR2341578A1 (fr)	1977-09-16	Nouveaux derives d'indolizine, leur procede de preparation ainsi que les compositions therapeutiques les contenant
PT76573A (fr)	1983-05-01	Procede de preparation de derives d'imidazo <1,2-a> pyridine et de compositions pharmaceutiques les contenant
LU78813A1 (fr)	1978-09-18	Nouvelles imidazo(1,2-a)quinoxalines substituees en position 4,leur procede de preparation et medicament les contenant
BE862278A (fr)	1978-06-23	Nouveaux composes heterocycliques, leur procede de preparation et medicament les contenant
BE884076A (fr)	1980-12-29	Nouveaux tripeptides, leur preparation et les medicaments qui les contiennent
FR2496100B1 (fr)	1985-06-14	Derives de la pyrazoline, leur preparation et medicaments contenant ces substances
BE884620A (fr)	1981-02-04	Nouveaux derives d'halovincamone, leur procede de preparation et medicaments les contenant
LU79007A1 (fr)	1979-09-06	Nouveaux derives semi-synthetiques de 4"-amino-oleandomycine,leur procede de preparation et medicament les contenant
LU81182A1 (fr)	1979-11-07	Nouveaux derives de l'isoquinoleine,leur preparation et les compositions pharmaceutiques qui les contiennent
FR2528044B1 (fr)	1986-01-03	Derives d'isoquinoleine, leur procede de preparation et medicaments les contenant
FR2468598B1 (fr)	1986-03-07	Thiazolidones-4 substituees en 2, leur procede de preparation et les medicaments les contenant
FR2508040B1 (fr)	1986-07-04	Derives de proline, leur procede de preparation et medicament les contenant
BE860126A (fr)	1978-04-26	Derives de 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols leur procede de preparation et compositions pharmaceutiques les contenant
BE863851A (fr)	1978-08-10	2,4-dichlorophenyl-imidazolyl-ethanones ou -ethanols, leur procede de preparation et medicament les contenant
BE882674A (fr)	1980-10-08	Derives d'aminoisoquinoleine, leur procede de preparation et medicaments les contenant
PT70107A (fr)	1979-09-01	Procede de preparation de nouveaux derives de 1,3-benzoxazine-2,4-dione et des compositions pharmaceutiques les contenant
BE860247A (fr)	1978-04-28	Nouveaux derives 1-(4-phenoxy-phenyl)-1,3,5-triaziniques leur procede de preparation et medicament les contenant
BE896465A (fr)	1983-10-14	Nouveaux derives du benzimidazole, leur preparation et les medicaments qui les contiennent
FR2496658B1 (fr)	1985-06-07	Derives de l'acide nicotinique, leur preparation et medicament contenant ces substances