BE901665A - Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer. - Google Patents

Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer.

Info

Publication number
BE901665A
BE901665A BE0/214459A BE214459A BE901665A BE 901665 A BE901665 A BE 901665A BE 0/214459 A BE0/214459 A BE 0/214459A BE 214459 A BE214459 A BE 214459A BE 901665 A BE901665 A BE 901665A
Authority
BE
Belgium
Prior art keywords
pharmaceutical composition
preparing
same
water
substance
Prior art date
Application number
BE0/214459A
Other languages
English (en)
Inventor
F Carli
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE901665A publication Critical patent/BE901665A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un polymère gonflable à l'eau insoluble dans l'eau est chargé d'une substance biologiquement active ou d'une substance qui est convertie in vivo en substance biologiquement active, par exemple un médicament ou un précurseur de médicament, par préparation et broyage d'un mélange de ladite substance avec un polymère gonflable à l'eau insoluble dans l'eau dans un rapport des poids substance : polymère de 1 : 0,1 à 1 : 100 ; le polymère ainsi chargé est utilisable comme composition pharmaceutique.
BE0/214459A 1984-02-08 1985-02-06 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer. BE901665A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403359A GB8403359D0 (en) 1984-02-08 1984-02-08 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BE901665A true BE901665A (fr) 1985-08-06

Family

ID=10556299

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214459A BE901665A (fr) 1984-02-08 1985-02-06 Composition pharmaceutique a biodisponibilite elevee et procede pour la preparer.

Country Status (7)

Country Link
US (1) US4639370A (fr)
JP (1) JPH0717496B2 (fr)
BE (1) BE901665A (fr)
DE (1) DE3503681A1 (fr)
FR (1) FR2559064B1 (fr)
GB (2) GB8403359D0 (fr)
IT (1) IT1221012B (fr)

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IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
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DE10125509A1 (de) * 2001-05-23 2002-12-12 Hexal Ag Lösungsmittelfreie Homogenisatherstellung
DE60223382T2 (de) * 2001-06-29 2008-09-11 Eurand Pharmaceuticals Ltd., Bray Verfahren für die thermodynamische aktivierung von wasserlöslichen arzneimitteln, die in vernetzten polymeren geladen sind
US20050019390A1 (en) * 2001-10-26 2005-01-27 John Kohnke Dosage system and dosage vehicle therefor
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
AUPS244002A0 (en) * 2002-05-20 2002-06-13 John Kohnke Products Pty Ltd Agent delivery system
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
US20070099996A1 (en) * 2003-05-20 2007-05-03 Shashikanth Isloor Pharmaceutical compositions of acitretin
WO2005000273A1 (fr) * 2003-06-27 2005-01-06 Bioprogress S.P.A. Produit composite obtenu par broyage d'un principe actif avec un copolymere n-vinyle-2-pyrrolidone/vinyle-acetate
RU2261095C1 (ru) * 2004-01-09 2005-09-27 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственная форма, обладающая нестероидным противовоспалительным действием, и способ ее изготовления
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
US7611630B2 (en) * 2004-03-30 2009-11-03 Bend Research, Inc. Method and device for evaluation of pharmaceutical compositions
US20100062073A1 (en) * 2006-11-29 2010-03-11 Ronald Arthur Beyerinck Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
WO2008135852A2 (fr) * 2007-05-03 2008-11-13 Pfizer Products Inc. Compositions pharmaceutiques comprenant des nanoparticules et de la caséine
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US8309129B2 (en) * 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
EP2162120B1 (fr) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticules comportant un polymère cellulosique non ionisable et un copolymère bloc amphiphile non ionisable
WO2008149230A2 (fr) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticules comprenant un médicament, un polymère cellulosique non ionisable et du tocophéryl polyéthylène glycol succinate
EP2178518A2 (fr) * 2007-07-13 2010-04-28 Bend Research, Inc Nanoparticules comprenant des polymères cellulosiques ionisables faiblement solubles dans l'eau
EP2231169B1 (fr) * 2007-12-06 2016-05-04 Bend Research, Inc. Compositions pharmaceutiques comprenant des nanoparticules et une matière de remise en suspension
EP2240162A4 (fr) * 2007-12-06 2013-10-09 Bend Res Inc Nanoparticules comprenant un polymère non ionisable et un copolymère de méthacrylate fonctionnalisé par amine
UA106231C2 (uk) 2009-04-24 2014-08-11 Айсьютика Пти Лтд Разова доза фармацевтичної композиції індометацину (варіанти)
JP5530716B2 (ja) * 2009-12-28 2014-06-25 ライオン株式会社 生薬含有錠剤、生薬含有錠剤用の生薬担持粒子の製造方法
ITMI20120092A1 (it) 2012-01-26 2013-07-27 Micro Macinazione S A Compositi di inclusione farmaco-carrier preparati con processo di attivazione meccano-chimica mediante mulini a getto di fluido ad alta energia

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Also Published As

Publication number Publication date
DE3503681C2 (fr) 1991-09-19
GB2153678A (en) 1985-08-29
DE3503681A1 (de) 1985-08-08
US4639370A (en) 1987-01-27
GB8403359D0 (en) 1984-03-14
GB8503034D0 (en) 1985-03-06
FR2559064B1 (fr) 1990-09-07
JPH0717496B2 (ja) 1995-03-01
IT8519433A0 (it) 1985-02-07
GB2153678B (en) 1988-04-13
FR2559064A1 (fr) 1985-08-09
JPS60181030A (ja) 1985-09-14
IT1221012B (it) 1990-06-21

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: *FARMITALIA CARLO ERBA S.R.L.

Effective date: 20050206

RE20 Patent expired

Owner name: *FARMITALIA CARLO ERBA S.R.L.

Effective date: 20050206