BE904699A - Acides hydroxamiques de beta-lactames o-sulfates, leurs sels d'addition d'acide, ainsi que leur preparation et leur utilisation. - Google Patents

Acides hydroxamiques de beta-lactames o-sulfates, leurs sels d'addition d'acide, ainsi que leur preparation et leur utilisation.

Info

Publication number
BE904699A
BE904699A BE0/216606A BE216606A BE904699A BE 904699 A BE904699 A BE 904699A BE 0/216606 A BE0/216606 A BE 0/216606A BE 216606 A BE216606 A BE 216606A BE 904699 A BE904699 A BE 904699A
Authority
BE
Belgium
Prior art keywords
lactames
sulphates
beta
preparation
well
Prior art date
Application number
BE0/216606A
Other languages
English (en)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of BE904699A publication Critical patent/BE904699A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Composés répondant à la fornule ci dessous et leurs sels pharmaceutiquement acceptable, formule dans laquelle les différents symboles ont différentes significations, ces composés présentant une activité antibactérienne.
BE0/216606A 1985-04-29 1986-04-29 Acides hydroxamiques de beta-lactames o-sulfates, leurs sels d'addition d'acide, ainsi que leur preparation et leur utilisation. BE904699A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/728,432 US4638060A (en) 1985-04-29 1985-04-29 O-sulfated spiro β-lactam hydroxamic acids

Publications (1)

Publication Number Publication Date
BE904699A true BE904699A (fr) 1986-08-18

Family

ID=24926831

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/216606A BE904699A (fr) 1985-04-29 1986-04-29 Acides hydroxamiques de beta-lactames o-sulfates, leurs sels d'addition d'acide, ainsi que leur preparation et leur utilisation.

Country Status (20)

Country Link
US (1) US4638060A (fr)
JP (1) JPS61257965A (fr)
AU (1) AU601944B2 (fr)
BE (1) BE904699A (fr)
CA (1) CA1273938A (fr)
CH (1) CH668073A5 (fr)
DE (1) DE3614317A1 (fr)
DK (1) DK190286A (fr)
ES (1) ES8800916A1 (fr)
FI (1) FI861693A7 (fr)
FR (1) FR2581062B1 (fr)
GB (1) GB2174392B (fr)
HU (1) HU194822B (fr)
IE (1) IE59630B1 (fr)
IT (1) IT1215652B (fr)
NL (1) NL8601051A (fr)
NZ (1) NZ215665A (fr)
PT (1) PT82467B (fr)
SE (1) SE8601963L (fr)
ZA (1) ZA862429B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013110643A1 (fr) 2012-01-24 2013-08-01 Aicuris Gmbh & Co. Kg Composés de bêta-lactame à substitution amidine, leur préparation et leur utilisation en tant qu'agents antibactériens

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143913A (en) * 1988-04-04 1992-09-01 E. R. Squibb & Sons, Inc. [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
US20140275007A1 (en) * 2013-03-14 2014-09-18 Rempex Pharmaceuticals, Inc. Oxamazin antibiotics
CN113754651B (zh) 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CN115463219A (zh) * 2021-11-09 2022-12-13 中国医学科学院医药生物技术研究所 包含β-内酰胺类化合物的药物组合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4260743A (en) * 1979-12-31 1981-04-07 Gist-Brocades N.V. Preparation of β-lactams and intermediates therefor
US4337197A (en) * 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates
JPS586589A (ja) 1981-07-01 1983-01-14 Hitachi Ltd 論理回路
JPS58113174A (ja) * 1981-12-26 1983-07-05 Toyama Chem Co Ltd 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
JPS58194856A (ja) 1982-05-10 1983-11-12 Yamanouchi Pharmaceut Co Ltd 新規２−アゼチジノン誘導体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013110643A1 (fr) 2012-01-24 2013-08-01 Aicuris Gmbh & Co. Kg Composés de bêta-lactame à substitution amidine, leur préparation et leur utilisation en tant qu'agents antibactériens

Also Published As

Publication number Publication date
FI861693A0 (fi) 1986-04-22
IT1215652B (it) 1990-02-22
IE861067L (en) 1986-10-29
IT8620227A0 (it) 1986-04-28
FR2581062A1 (fr) 1986-10-31
IE59630B1 (en) 1994-03-09
PT82467A (en) 1986-05-01
GB2174392A (en) 1986-11-05
SE8601963L (sv) 1986-10-30
ES8800916A1 (es) 1987-12-01
DE3614317A1 (de) 1986-11-06
CA1273938C (fr) 1990-09-11
AU601944B2 (en) 1990-09-27
FI861693A7 (fi) 1986-10-30
ES554438A0 (es) 1987-12-01
FR2581062B1 (fr) 1990-10-19
HU194822B (en) 1988-03-28
GB8609596D0 (en) 1986-05-21
SE8601963D0 (sv) 1986-04-28
JPS61257965A (ja) 1986-11-15
DK190286A (da) 1986-10-30
ZA862429B (en) 1986-11-26
CA1273938A (fr) 1990-09-11
CH668073A5 (fr) 1988-11-30
GB2174392B (en) 1988-11-09
HUT41384A (en) 1987-04-28
PT82467B (pt) 1988-03-03
NZ215665A (en) 1988-11-29
NL8601051A (nl) 1986-11-17
DK190286D0 (da) 1986-04-24
US4638060A (en) 1987-01-20
AU5556886A (en) 1986-11-06

Similar Documents

Publication Publication Date Title
BE904421A (fr) Derives heterocycliques aromatiques et leur application dans les domaines therapeutique et cosmetique.
LU90949I2 (fr) Esters aminoalcohol d'acide thienylcarboxyliques leurs produits quaternaires leur préparation et l'utilisation de ces composés
FR2441625A1 (fr) (d2-imidazolinyl-2 amino)-5 pyrimidines, procede pour les preparer, et medicaments qui en contiennent
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
TNSN87012A1 (fr) Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
FR2359144A1 (fr) Sels de l'acide clavulanique utilisable comme medicaments
FR2387235A1 (fr) Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
FR2415630A1 (fr) Nouvelles 5-vinyl-2-pyrrolidones, utiles notamment dans la preparation des acides 4-amino-5-hexenoique et 4-amino-5-hexynoique, et leur preparation
BE904699A (fr) Acides hydroxamiques de beta-lactames o-sulfates, leurs sels d'addition d'acide, ainsi que leur preparation et leur utilisation.
FR2450820A1 (fr) Nouveaux derives d'acides 1- (o-mercaptoacyl) -4,5-dihydropyrazole-5-carboxyliques, utiles notamment comme agents hypotenseurs, et leur procede de preparation
FR2432520A1 (fr) Nouvelles imidazoquinoxalines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
FR2410641A1 (fr) Formes racemiques et optiquement actives de (biphenylyl-4)-2 n-(diethylamino alkyl) propionamides et de leurs sels utiles comme agents spasmolytiques et procedes de preparation
BE1002427A3 (fr) Nouvel acide piperazinecarboxylique, sa preparation et son utilisation comme medicament.
FR2388789A1 (fr) Derives d'acide benzoique, leur procede de preparation et leur application therapeutique
FR2401922A1 (fr) Picolylamides d'acides 4-hydroxy-isophtaliques substitues, leur preparation et leurs utilisations therapeutiques
FR2410640A1 (fr) Derives de phenoxyalcanolamines, leur preparation et leurs utilisations therapeutiques
FR2457868A1 (fr) Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques
FR2455569A1 (fr) Nouvelles isoprenylamines et leurs sels acides d'addition et leur utilisation comme substances actives dans des compositions pharmaceutiques antivirales pour animaux vertebres
FR2449687A1 (fr) Derives de phenothiazine et leur application en therapeutique
BE1003280A3 (fr) Derives oxo-isoindoliniques optiquement actifs.
FR2408589A1 (fr) Nouvelles 13,14-bisdeshydroprostaglandines, leur procede de preparation et leurs applications therapeutiques
FR2396014A1 (fr) Esters d'acides silylacetyleniques et leurs utilisations therapeutiques, notamment comme antibacteriens
DK248484A (da) Isoquinolinderivater
FR2450106A1 (fr) Compositions pharmaceutiques ou veterinaires renfermant une quantite physiologiquement active d'une phenylethylamine, a activite de stimulation sexuelle
ATE71093T1 (de) 7-oxo-pgi2-ephedrinsalze, deren herstellung und diese verbindungen enthaltende pharmazeutsche praeparate.

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: E.R. SQUIBB ET SONS INC.

Effective date: 19950430