BG101392A - Method of treating diabetes mellitus using kgf - Google Patents

Method of treating diabetes mellitus using kgf

Info

Publication number: BG101392A
Authority: BG; Bulgaria
Prior art keywords: kgf; diabetes mellitus; treating diabetes; mammals; pharmaceutical compositions
Prior art date: 1994-10-13

Application number

BG101392A

Other languages

Bulgarian (bg)

English (en)

Inventor

Lea Aukerman

Francis Pierce

Original Assignee

Amgen Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-13

Filing date

1997-04-07

Publication date

1997-10-31

1997-04-07 Application filed by Amgen Inc. filed Critical Amgen Inc.

1997-10-31 Publication of BG101392A publication Critical patent/BG101392A/xx

Links

206010012601 diabetes mellitus Diseases 0.000 title abstract 2
102000003972 Fibroblast growth factor 7 Human genes 0.000 abstract 1
108090000385 Fibroblast growth factor 7 Proteins 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

BG101392A 1994-10-13 1997-04-07 Method of treating diabetes mellitus using kgf BG101392A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US32334094A	1994-10-13	1994-10-13
US32347594A	1994-10-13	1994-10-13
US48782595A	1995-06-07	1995-06-07
PCT/IB1995/000992 WO1996011950A1 (fr)	1994-10-13	1995-10-12	Procede de traitement du diabete sucre a l'aide du facteur de croissance des keratinocytes

Publications (1)

Publication Number	Publication Date
BG101392A true BG101392A (en)	1997-10-31

Family

ID=27406268

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BG101392A BG101392A (en)	1994-10-13	1997-04-07	Method of treating diabetes mellitus using kgf
BG101408A BG63167B1 (bg)	1994-10-13	1997-04-11	Аналози на кератиноцитния растежен фактор

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BG101408A BG63167B1 (bg)	1994-10-13	1997-04-11	Аналози на кератиноцитния растежен фактор

Country Status (23)

Country	Link
EP (2)	EP0804479B1 (fr)
JP (2)	JP4216329B2 (fr)
KR (1)	KR100278597B1 (fr)
CN (1)	CN1168678A (fr)
AT (2)	ATE342278T1 (fr)
AU (1)	AU3707795A (fr)
BG (2)	BG101392A (fr)
BR (2)	BR9509329A (fr)
CA (2)	CA2202075C (fr)
CZ (3)	CZ297328B6 (fr)
DE (2)	DE69535264T2 (fr)
DK (2)	DK0785948T3 (fr)
EE (2)	EE03975B1 (fr)
ES (2)	ES2196082T3 (fr)
FI (2)	FI971420A7 (fr)
HU (2)	HU226168B1 (fr)
NO (2)	NO318761B1 (fr)
NZ (2)	NZ505502A (fr)
PL (2)	PL182888B1 (fr)
PT (2)	PT785948E (fr)
SI (2)	SI0804479T1 (fr)
SK (2)	SK284534B6 (fr)
WO (2)	WO1996011949A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2250213C2 (ru)	1989-01-31	2005-04-20	Джеффри С. РУБИН	Выделенный белок фактора роста кератиноцита (kgf), рекомбинантная молекула днк, вектор, способ конструирования клетки-хозяина, способ получения белка, фармацевтическая композиция
CA2166278A1 (fr)	1993-06-29	1995-01-12	Denis J. Gospodarowicz	Facteur de croissance tronque des keratinocytes, possedant une plus grande activite biologique
US7084119B2 (en)	1993-06-29	2006-08-01	Chiron Corporation	Truncated keratinocyte growth factor (KGF) having increased biological activity
SI0785949T1 (en) *	1994-10-13	2003-08-31	Amgen Inc.	Method for purifying keratinocyte growth factors
US7232667B2 (en)	1995-02-14	2007-06-19	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 polynucleotides
US6693077B1 (en)	1995-02-14	2004-02-17	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US6077692A (en)	1995-02-14	2000-06-20	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
DE69603269T3 (de) *	1995-04-27	2007-02-22	Coöperatie Cosun U.A.	Derivate von inulin
ES2218666T3 (es) *	1996-10-15	2004-11-16	Amgen Inc.,	Producto a base del factor de crecimiento de queratinocitos-2 (kggf-2).
SI0935652T1 (en) *	1996-10-15	2004-06-30	Amgen Inc.	Keratinocyte growth factor-2 products
US6743422B1 (en)	1996-10-15	2004-06-01	Amgen, Inc.	Keratinocyte growth factor-2 products
US7153943B2 (en)	1997-07-14	2006-12-26	Bolder Biotechnology, Inc.	Derivatives of growth hormone and related proteins, and methods of use thereof
US7495087B2 (en)	1997-07-14	2009-02-24	Bolder Biotechnology, Inc.	Cysteine muteins in the C-D loop of human interleukin-11
US20080076706A1 (en)	1997-07-14	2008-03-27	Bolder Biotechnology, Inc.	Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
ES2297889T3 (es)	1997-07-14	2008-05-01	Bolder Biotechnology, Inc.	Derivados de hormona de crecimiento y proteinas relacionadas.
WO1999032135A1 (fr)	1997-12-22	1999-07-01	Human Genome Sciences, Inc.	Formulations du facteur-2 de croissance des keratinocytes
US6869927B1 (en)	1997-12-22	2005-03-22	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 formulations
US6242666B1 (en)	1998-12-16	2001-06-05	The Scripps Research Institute	Animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
US8288126B2 (en)	1999-01-14	2012-10-16	Bolder Biotechnology, Inc.	Methods for making proteins containing free cysteine residues
CA2359345A1 (fr) *	1999-01-14	2000-07-20	Bolder Biotechnology, Inc.	Techniques permettant de produire des proteines contenant des residus cysteine libres
US6248725B1 (en)	1999-02-23	2001-06-19	Amgen, Inc.	Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
CN1491231A (zh) *	2001-02-06	2004-04-21	Ĭ��ר��޹�˾	免疫原性减弱的经修饰角质形成细胞生长因子(kgf)
AU2002326742B2 (en) *	2001-08-21	2007-05-31	Novartis Vaccines And Diagnostics, Inc.	KGF polypeptide compositions
AU2007214362B2 (en) *	2001-08-21	2009-11-26	Novartis Vaccines And Diagnostics, Inc.	KGF polypeptide compositions
AU2005317166B2 (en)	2004-12-15	2009-09-10	Biovitrum Ab (Publ)	Therapeutic formulations of keratinocyte growth factor
CN102242124B (zh) *	2010-05-10	2013-05-22	齐鲁制药有限公司	改造的角化细胞生长因子基因及其在酵母中的表达
KR102440312B1 (ko) *	2020-08-28	2022-09-05	한국해양과학기술원	온도안정성을 향상시킨 fgf7 폴리펩타이드 및 그 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4959314A (en) *	1984-11-09	1990-09-25	Cetus Corporation	Cysteine-depleted muteins of biologically active proteins
JPH01137994A (ja) *	1987-08-10	1989-05-30	Shionogi & Co Ltd	ｒｅｇ蛋白質
WO1990000877A1 (fr) *	1988-07-27	1990-02-08	Marjan International Pty Ltd	Machine a tendre les tapis
RU2250213C2 (ru) *	1989-01-31	2005-04-20	Джеффри С. РУБИН	Выделенный белок фактора роста кератиноцита (kgf), рекомбинантная молекула днк, вектор, способ конструирования клетки-хозяина, способ получения белка, фармацевтическая композиция
JP3303211B2 (ja) *	1991-04-26	2002-07-15	武田薬品工業株式会社	ｂＦＧＦムテインおよびその製造法
AU707340B2 (en) *	1993-03-26	1999-07-08	Biovitrum Ab (Publ)	Therapeutic uses of keratinocyte growth factor
US5348563A (en) *	1993-06-29	1994-09-20	Honeywell Inc.	Air purifying apparatus
CA2166278A1 (fr) *	1993-06-29	1995-01-12	Denis J. Gospodarowicz	Facteur de croissance tronque des keratinocytes, possedant une plus grande activite biologique
GB9315501D0 (en) *	1993-07-27	1993-09-08	Ici Plc	Surfactant compositions
AU7475694A (en) *	1993-08-02	1995-02-28	Prizm Pharmaceuticals, Inc.	Monogenous preparations of cytotoxic conjugates

1995
- 1995-10-12 WO PCT/IB1995/000971 patent/WO1996011949A2/fr not_active Ceased
- 1995-10-12 DK DK95934793T patent/DK0785948T3/da active
- 1995-10-12 BR BR9509329A patent/BR9509329A/pt not_active Application Discontinuation
- 1995-10-12 HU HU9901255A patent/HU226168B1/hu not_active IP Right Cessation
- 1995-10-12 KR KR1019970702343A patent/KR100278597B1/ko not_active Expired - Fee Related
- 1995-10-12 CA CA002202075A patent/CA2202075C/fr not_active Expired - Fee Related
- 1995-10-12 PT PT95934793T patent/PT785948E/pt unknown
- 1995-10-12 WO PCT/IB1995/000992 patent/WO1996011950A1/fr not_active Ceased
- 1995-10-12 DE DE69535264T patent/DE69535264T2/de not_active Expired - Lifetime
- 1995-10-12 AU AU37077/95A patent/AU3707795A/en not_active Abandoned
- 1995-10-12 FI FI971420A patent/FI971420A7/fi unknown
- 1995-10-12 SI SI9530728T patent/SI0804479T1/sl unknown
- 1995-10-12 PL PL95319784A patent/PL182888B1/pl not_active IP Right Cessation
- 1995-10-12 EE EE9700081A patent/EE03975B1/xx not_active IP Right Cessation
- 1995-10-12 AT AT95934808T patent/ATE342278T1/de active
- 1995-10-12 JP JP51307796A patent/JP4216329B2/ja not_active Expired - Fee Related
- 1995-10-12 HU HU9901071A patent/HUT78050A/hu unknown
- 1995-10-12 EE EE9700225A patent/EE9700225A/xx unknown
- 1995-10-12 PL PL95320484A patent/PL320484A1/xx unknown
- 1995-10-12 BR BR9509269A patent/BR9509269A/pt not_active Application Discontinuation
- 1995-10-12 EP EP95934808A patent/EP0804479B1/fr not_active Expired - Lifetime
- 1995-10-12 DE DE69530403T patent/DE69530403T2/de not_active Expired - Lifetime
- 1995-10-12 CN CN95196410A patent/CN1168678A/zh active Pending
- 1995-10-12 DK DK95934808T patent/DK0804479T3/da active
- 1995-10-12 ES ES95934793T patent/ES2196082T3/es not_active Expired - Lifetime
- 1995-10-12 NZ NZ505502A patent/NZ505502A/en not_active IP Right Cessation
- 1995-10-12 CZ CZ0105097A patent/CZ297328B6/cs not_active IP Right Cessation
- 1995-10-12 EP EP95934793A patent/EP0785948B1/fr not_active Expired - Lifetime
- 1995-10-12 SK SK455-97A patent/SK284534B6/sk not_active IP Right Cessation
- 1995-10-12 ES ES95934808T patent/ES2273338T3/es not_active Expired - Lifetime
- 1995-10-12 CZ CZ97981A patent/CZ98197A3/cs unknown
- 1995-10-12 AT AT95934793T patent/ATE237633T1/de active
- 1995-10-12 CZ CZ20023953A patent/CZ297329B6/cs not_active IP Right Cessation
- 1995-10-12 SK SK431-97A patent/SK43197A3/sk unknown
- 1995-10-12 SI SI9530654T patent/SI0785948T1/xx unknown
- 1995-10-12 CA CA002201940A patent/CA2201940C/fr not_active Expired - Fee Related
- 1995-10-12 JP JP51307696A patent/JP4426646B2/ja not_active Expired - Fee Related
- 1995-10-12 PT PT95934808T patent/PT804479E/pt unknown
1997
- 1997-04-04 NO NO19971568A patent/NO318761B1/no not_active IP Right Cessation
- 1997-04-04 NO NO971566A patent/NO971566L/no unknown
- 1997-04-07 BG BG101392A patent/BG101392A/xx unknown
- 1997-04-11 BG BG101408A patent/BG63167B1/bg unknown
- 1997-04-11 FI FI971536A patent/FI120040B/fi not_active IP Right Cessation
1999
- 1999-04-09 NZ NZ335109A patent/NZ335109A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP4426646B2 (ja)	2010-03-03
HUT78058A (hu)	1999-07-28
NZ335109A (en)	2000-08-25
WO1996011949A3 (fr)	1996-12-12
PT785948E (pt)	2003-09-30
ES2273338T3 (es)	2007-05-01
CZ297328B6 (cs)	2006-11-15
HUT78050A (hu)	1999-07-28
AU3707795A (en)	1996-05-06
PL320484A1 (en)	1997-09-29
SI0804479T1 (sl)	2006-12-31
FI971420L (fi)	1997-04-04
ATE342278T1 (de)	2006-11-15
NO971566D0 (no)	1997-04-04
DE69530403D1 (de)	2003-05-22
CA2201940C (fr)	2009-05-12
BR9509329A (pt)	1997-10-14
BG63167B1 (bg)	2001-05-31
PL182888B1 (pl)	2002-03-29
SK45597A3 (en)	1999-02-11
AU3708395A (en)	1996-05-06
EP0785948B1 (fr)	2003-04-16
CZ105097A3 (cs)	1998-10-14
FI971420A0 (fi)	1997-04-04
FI971420A7 (fi)	1997-04-04
KR100278597B1 (ko)	2001-01-15
DK0804479T3 (da)	2007-01-29
SK43197A3 (en)	1999-03-12
CZ297329B6 (cs)	2006-11-15
JPH10507193A (ja)	1998-07-14
ATE237633T1 (de)	2003-05-15
NO318761B1 (no)	2005-05-02
JP4216329B2 (ja)	2009-01-28
NO971568D0 (no)	1997-04-04
EE03975B1 (et)	2003-02-17
HU226168B1 (en)	2008-05-28
DK0785948T3 (da)	2003-08-04
FI971536L (fi)	1997-06-09
CZ98197A3 (cs)	1998-11-11
PL319784A1 (en)	1997-08-18
JPH10507080A (ja)	1998-07-14
CA2201940A1 (fr)	1996-04-25
BR9509269A (pt)	1997-12-23
PT804479E (pt)	2007-02-28
EP0804479B1 (fr)	2006-10-11
FI971536A0 (fi)	1997-04-11
FI120040B (fi)	2009-06-15
EP0785948A1 (fr)	1997-07-30
AU681546B2 (en)	1997-08-28
WO1996011950A1 (fr)	1996-04-25
SI0785948T1 (en)	2003-08-31
CA2202075A1 (fr)	1996-04-25
NO971566L (no)	1997-04-14
CN1168678A (zh)	1997-12-24
ES2196082T3 (es)	2003-12-16
NZ505502A (en)	2005-01-28
EE9700225A (et)	1998-02-16
EP0804479A1 (fr)	1997-11-05
CA2202075C (fr)	2003-12-09
SK284534B6 (sk)	2005-06-02
DE69530403T2 (de)	2003-10-30
NO971568L (no)	1997-06-12
BG101408A (bg)	1997-12-30
DE69535264D1 (de)	2006-11-23
WO1996011949A2 (fr)	1996-04-25
DE69535264T2 (de)	2007-02-01
EE9700081A (et)	1997-10-15

Publication	Publication Date	Title
BG101392A (en)	1997-10-31	Method of treating diabetes mellitus using kgf
FI965203A7 (fi)	1996-12-23	Morfiinia, polypyrrolidonia ja polyalkyleenioksidia sisältävä koostumus
BR9502707A (pt)	1996-06-04	Composto composição farmacêutica e método para o tratamento de uma afecção
BG99261A (en)	1995-06-30	Steroid glycosides for the treatment of hyperchlesterolemia
NO982055D0 (no)	1998-05-06	2-alkylpyrrolidiner
BR9507758A (pt)	1997-09-23	Fração de copolímero-1 e composição para o tratamento de esclerose múltipla
BG101835A (bg)	1998-05-29	Нови дипептидни амидини и използването им като инхибитори на тромбин
DE69822919D1 (de)	2004-05-13	Spezifische Antikörper zur Verwendung in der Herstellung pharmazeutischer Zusammensetzungen nützlich für die Vorbeugung oder Behandlung von Gastritis, Magen- und Zwölffingerdarmgeschwüren
ID29393A (id)	2001-08-30	Komposisi pengobatan kanker dan metoda penggunaan minyak-minyak esensil tanaman alamiah
FI953180A7 (fi)	1995-12-29	Sokeritaudin komplikaatioiden hoitamiseen tarkoitetut koostumukset
DE69603089D1 (de)	1999-08-05	Zusammensetzung zur behandlung von mauerwerk
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