BG105430A - Compositions and methods for the supply of powder active substance in the lungs - Google Patents

Compositions and methods for the supply of powder active substance in the lungs

Info

Publication number
BG105430A
BG105430A BG105430A BG10543001A BG105430A BG 105430 A BG105430 A BG 105430A BG 105430 A BG105430 A BG 105430A BG 10543001 A BG10543001 A BG 10543001A BG 105430 A BG105430 A BG 105430A
Authority
BG
Bulgaria
Prior art keywords
lungs
compositions
supply
methods
active substance
Prior art date
Application number
BG105430A
Other languages
Bulgarian (bg)
English (en)
Inventor
Andrew Clark
Mei-Chang Kuo
Cecily Lalor
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of BG105430A publication Critical patent/BG105430A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
BG105430A 1998-09-14 2001-04-10 Compositions and methods for the supply of powder active substance in the lungs BG105430A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10016398P 1998-09-14 1998-09-14
PCT/US1999/021109 WO2000015262A1 (en) 1998-09-14 1999-09-13 Dry powder active agent pulmonary delivery

Publications (1)

Publication Number Publication Date
BG105430A true BG105430A (en) 2001-12-29

Family

ID=22278404

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105430A BG105430A (en) 1998-09-14 2001-04-10 Compositions and methods for the supply of powder active substance in the lungs

Country Status (44)

Country Link
EP (1) EP1117442A1 (uk)
JP (1) JP2002524535A (uk)
KR (1) KR20010075063A (uk)
CN (1) CN1317977A (uk)
AP (1) AP1374A (uk)
AR (1) AR022090A1 (uk)
AU (1) AU753014B2 (uk)
BG (1) BG105430A (uk)
BR (1) BR9913722A (uk)
CA (1) CA2343920A1 (uk)
CO (1) CO5130023A1 (uk)
CZ (1) CZ2001829A3 (uk)
DZ (1) DZ2892A1 (uk)
EA (1) EA003476B1 (uk)
EE (1) EE200100151A (uk)
GE (1) GEP20043257B (uk)
GT (1) GT199900156A (uk)
HK (1) HK1042231A1 (uk)
HN (1) HN1999000159A (uk)
HR (1) HRP20010189A2 (uk)
HU (1) HUP0103837A3 (uk)
ID (1) ID28845A (uk)
IL (2) IL141562A0 (uk)
IS (1) IS5878A (uk)
LT (1) LT4897B (uk)
LV (1) LV12658B (uk)
MA (1) MA25590A1 (uk)
MY (1) MY129282A (uk)
NO (1) NO20011251L (uk)
NZ (1) NZ510168A (uk)
OA (1) OA11781A (uk)
PA (1) PA8481901A1 (uk)
PE (1) PE20001061A1 (uk)
PL (1) PL195574B1 (uk)
SA (1) SA99200718B1 (uk)
SK (1) SK3442001A3 (uk)
TN (1) TNSN99173A1 (uk)
TR (1) TR200101182T2 (uk)
TW (1) TWI226248B (uk)
UA (1) UA76085C2 (uk)
UY (1) UY25711A1 (uk)
WO (1) WO2000015262A1 (uk)
YU (1) YU24201A (uk)
ZA (1) ZA200101995B (uk)

Families Citing this family (33)

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US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
ATE555773T1 (de) 1999-06-09 2012-05-15 Sievers Robert E Überkritische fluidgestützte verneblung und blasen trochnen
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
CA2446904A1 (en) * 2001-05-24 2003-04-03 Alexza Pharmaceuticals, Inc. Delivery of drug esters through an inhalation route
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
CA2465675C (en) 2001-11-20 2008-06-10 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EA200401111A1 (ru) 2002-02-25 2005-02-24 Диффьюжн Фармасьютикалз Ллс Биполярные соли транс-каротиноидов и их применение
AU2003232081B2 (en) * 2002-07-03 2009-02-05 Brandeis University Central airway administration for systemic delivery of therapeutics
WO2004060352A1 (en) * 2002-12-19 2004-07-22 Pharmacia Corporation Non-hygroscopic formulation comprising a hydroscopic drug
DE10338403A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
PL2708225T3 (pl) * 2004-04-23 2019-07-31 Cydex Pharmaceuticals, Inc. Formulacja DPI zawierająca eter sulfoalkilowy cyklodekstryny
UA95903C2 (uk) * 2005-02-24 2011-09-26 Дифьюжен Фармасьютикалз Ллк Транс-каротиноїди, їх синтез, лікарська форма та застосування
RU2007137121A (ru) * 2005-03-09 2009-04-20 Оно Фармасьютикал Ко., Лтд. (Jp) Частица и препарат, содержащий указанную частицу
DK1945228T4 (da) 2005-10-26 2015-01-12 Cydex Pharmaceuticals Inc Sulfoalkyl-ether-cyclodextrin-sammensætninger og fremgangsmåder til fremstilling deraf
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US20080035143A1 (en) * 2006-08-14 2008-02-14 Sievers Robert E Human-powered dry powder inhaler and dry powder inhaler compositions
JP5315056B2 (ja) * 2006-10-25 2013-10-16 大日本住友製薬株式会社 固結抑制粒状製剤
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
CN101687757A (zh) 2007-04-13 2010-03-31 扩散药品有限公司 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
JP2011502125A (ja) 2007-10-31 2011-01-20 ディフュージョン・ファーマシューティカルズ・エルエルシー 小分子拡散を促進する新しい種類の治療法
DK2432502T3 (en) 2009-05-20 2018-03-12 Aeras STABLE, SPRAY DRIED, IMMUNOGENE, VIRUS COMPOSITIONS
KR101875843B1 (ko) 2009-06-22 2018-07-06 디퓨젼 파마슈티컬즈 엘엘씨 확산 촉진 화합물 및 그 화합물 단독 또는 혈전 용해제와 합쳐진 화합물의 용도
KR101891357B1 (ko) 2010-06-02 2018-08-24 디퓨젼 파마슈티컬즈 엘엘씨 양극성 트랜스 카로티노이드의 경구용 제형
NZ630040A (en) 2012-05-03 2016-10-28 Janssen Sciences Ireland Uc Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
BR112015010601B1 (pt) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
WO2015042352A1 (en) * 2013-09-20 2015-03-26 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
US11185523B2 (en) 2016-03-24 2021-11-30 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155573A (en) * 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
DE69732306T2 (de) * 1997-01-16 2006-01-12 Massachusetts Institute Of Technology, Cambridge Zubereitung von partikelhaltigen arzneimitteln zur inhalation
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant

Also Published As

Publication number Publication date
SK3442001A3 (en) 2001-11-06
HUP0103837A3 (en) 2002-11-28
MA25590A1 (fr) 2002-12-31
KR20010075063A (ko) 2001-08-09
EE200100151A (et) 2002-06-17
NO20011251L (no) 2001-04-17
LV12658A (lv) 2001-05-20
IL141562A0 (en) 2002-03-10
HK1042231A1 (zh) 2002-08-09
LT4897B (lt) 2002-02-25
EA200100300A1 (ru) 2001-10-22
PL346768A1 (en) 2002-02-25
HUP0103837A2 (hu) 2002-05-29
UA76085C2 (en) 2006-07-17
LV12658B (lv) 2001-09-20
AR022090A1 (es) 2002-09-04
SA99200718B1 (ar) 2006-11-04
ID28845A (id) 2001-07-05
IL141562A (en) 2007-07-24
CZ2001829A3 (cs) 2001-09-12
GEP20043257B (en) 2004-06-25
TWI226248B (en) 2005-01-11
OA11781A (en) 2005-07-26
LT2001021A (en) 2001-11-26
DZ2892A1 (fr) 2003-12-15
AP2001002093A0 (en) 2001-03-31
WO2000015262A1 (en) 2000-03-23
CN1317977A (zh) 2001-10-17
PE20001061A1 (es) 2000-10-08
AU6039799A (en) 2000-04-03
NO20011251D0 (no) 2001-03-13
EP1117442A1 (en) 2001-07-25
CO5130023A1 (es) 2002-02-27
UY25711A1 (es) 1999-11-17
HRP20010189A2 (en) 2005-04-30
ZA200101995B (en) 2002-03-11
PL195574B1 (pl) 2007-10-31
GT199900156A (es) 2001-03-07
CA2343920A1 (en) 2000-03-23
PA8481901A1 (es) 2002-04-25
YU24201A (sh) 2003-08-29
HN1999000159A (es) 1999-11-11
AP1374A (en) 2005-02-28
BR9913722A (pt) 2001-05-29
AU753014B2 (en) 2002-10-03
JP2002524535A (ja) 2002-08-06
IS5878A (is) 2001-03-05
TNSN99173A1 (fr) 2005-11-10
NZ510168A (en) 2003-09-26
MY129282A (en) 2007-03-30
EA003476B1 (ru) 2003-06-26
TR200101182T2 (tr) 2001-09-21

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