BG108492A - Използване на въглероден окис за подобряване на резултатите при трансплантация на тъкани и органи и потискане на апоптозата - Google Patents

Използване на въглероден окис за подобряване на резултатите при трансплантация на тъкани и органи и потискане на апоптозата

Info

Publication number
BG108492A
BG108492A BG108492A BG10849203A BG108492A BG 108492 A BG108492 A BG 108492A BG 108492 A BG108492 A BG 108492A BG 10849203 A BG10849203 A BG 10849203A BG 108492 A BG108492 A BG 108492A
Authority
BG
Bulgaria
Prior art keywords
organs
apoptosis
fabrics
transparency
improving
Prior art date
Application number
BG108492A
Other languages
Bulgarian (bg)
English (en)
Inventor
Fritz Bach
Edda Tobiasch
Miguel Soares
Leo OTTERBEIN
Jeanne GOSE
Original Assignee
Beth Israel Deaconess Medical Center, Inc
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27404726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG108492(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beth Israel Deaconess Medical Center, Inc, Yale University filed Critical Beth Israel Deaconess Medical Center, Inc
Publication of BG108492A publication Critical patent/BG108492A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG108492A 2001-06-21 2003-12-22 Използване на въглероден окис за подобряване на резултатите при трансплантация на тъкани и органи и потискане на апоптозата BG108492A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30028901P 2001-06-21 2001-06-21
US33434001P 2001-11-29 2001-11-29
US33797401P 2001-12-07 2001-12-07

Publications (1)

Publication Number Publication Date
BG108492A true BG108492A (bg) 2005-02-28

Family

ID=27404726

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108492A BG108492A (bg) 2001-06-21 2003-12-22 Използване на въглероден окис за подобряване на резултатите при трансплантация на тъкани и органи и потискане на апоптозата

Country Status (25)

Country Link
US (2) US7238469B2 (fr)
EP (2) EP1404811B1 (fr)
JP (1) JP4521183B2 (fr)
KR (1) KR20040032115A (fr)
CN (1) CN100502650C (fr)
AT (1) ATE413883T1 (fr)
AU (2) AU2002318377B2 (fr)
BG (1) BG108492A (fr)
BR (1) BR0210599A (fr)
CA (1) CA2451266A1 (fr)
CY (1) CY1108798T1 (fr)
CZ (1) CZ20033448A3 (fr)
DE (1) DE60229848D1 (fr)
DK (1) DK1404811T3 (fr)
ES (1) ES2316583T3 (fr)
HU (1) HUP0400371A3 (fr)
MX (1) MXPA03012031A (fr)
NO (1) NO20035637L (fr)
NZ (1) NZ562962A (fr)
PL (1) PL367544A1 (fr)
PT (1) PT1404811E (fr)
SG (1) SG147305A1 (fr)
SI (1) SI1404811T1 (fr)
SK (1) SK15942003A3 (fr)
WO (1) WO2003000114A2 (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8128963B2 (en) 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US7678390B2 (en) 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
MXPA03012031A (es) 2001-06-21 2005-07-01 Univ Yale El monoxido de carbono mejoraresultados en transplantes de tejido y organo y suprime apoptosis.
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
NZ534912A (en) 2002-02-04 2007-08-31 Alfama Investigacao E Desenvol supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
BRPI0307673A2 (pt) 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
RS91004A (sr) 2002-04-15 2007-02-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Postupci za lečenje ileusa
WO2003088748A1 (fr) 2002-04-15 2003-10-30 Beth Israel Deaconess Medical Center Utilisation d'heme-oxygenase-1 et produits de degradation d'heme
EP1499328B1 (fr) 2002-04-15 2015-09-16 University of Pittsburgh - Of the Commonwealth System of Higher Education Methodes de traitement de l'enterocolite necrosante neonatale
JP4549847B2 (ja) 2002-05-17 2010-09-22 イエール ユニバーシティ 肝炎の治療方法
UA87438C2 (ru) * 2002-06-05 2009-07-27 Йельский Университет Способы лечения или профилактики рака, способ проведения хирургической операции по удалению рака и применения монооксида углерода
CN1674942A (zh) * 2002-06-21 2005-09-28 联邦高等教育系统匹兹堡大学 氧化氮、血红素加氧酶－1和血红素降解产物的药学用途
PL377733A1 (pl) * 2002-11-07 2006-02-06 University Of Pittsburgh Of The Commonwealth System Of Higher Education Leczenie wstrząsu krwotocznego
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20070207217A1 (en) * 2003-02-03 2007-09-06 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO
CN1901795B (zh) * 2003-10-22 2014-03-26 弗雷德哈钦森癌症研究中心 用于在细胞，组织，器官，和有机体中诱导停滞的方法，组合物和装置
EP1552840A1 (fr) * 2004-01-07 2005-07-13 Aga Ab Mélange de xénon et de monoxyde de carbone pour la protection de cellules
WO2006096774A2 (fr) 2005-03-07 2006-09-14 Sangart, Inc. Composition et methodes de diffusion de monoxyde de carbone (co) et de monoxyde d'azote (no) dans un tissu en utilisant des proteines heme comme supports
EP1937059A2 (fr) * 2005-07-27 2008-07-02 University Of North Carolina At Charlotte Composition et procede pour la restauration et la preservation d'organes de transplantation provenant de donneurs par donation suite a une mort cardiaque
US20070207993A1 (en) * 2005-12-20 2007-09-06 Alfama - Investigacao E Desenvolvimetno De Productos Farmaceuticos Lda Molybdenum carbonyl complexes for treating rheumatoid arthritis and other inflammatory diseases
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
EP2514473A1 (fr) 2006-11-07 2012-10-24 The General Hospital Corporation Dispositif d'alimentation d'oxyde nitrique
CA2763111C (fr) 2009-05-27 2019-09-24 Ino Therapeutics Llc Dispositifs et procedes d'engagement d'un ensemble indexe de soupape et de canette sous pression dote d'un collier et d'actionnement lineaire par un ensemble de plongeur en communication d'ecoulement avec un dispositif de regulation de l'administration de medicaments
AU2009202685B1 (en) 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
JP6118731B2 (ja) * 2011-01-14 2017-04-19 チルドレンズ ホスピタル ロサンゼルス 鎌状赤血球疾患を含む、疾患の治療のための一酸化炭素の溶液
US8927750B2 (en) 2011-02-04 2015-01-06 Universitaet Zu Koeln Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules
WO2012125955A2 (fr) 2011-03-16 2012-09-20 Mayo Foundation For Medical Education And Research Procédés et matériaux pour prolonger le stockage utile des préparations d'hématies et des préparations de plaquettes
EP2699242B1 (fr) 2011-04-19 2017-11-01 Alfama, Inc. Molécules libérant du monoxyde de carbone et utilisations de celles-ci
EP3391891A3 (fr) * 2011-06-10 2019-01-02 VERO Biotech LLC Récipient sous pression d'oxyde nitrique (no)
JP6134710B2 (ja) 2011-07-21 2017-05-24 アルファーマ インコーポレイテッドＡｌｆａｍａ，Ｉｎｃ． 一酸化ルテニウム放出分子およびその使用
CA2844660A1 (fr) 2011-08-09 2013-02-14 Leo E. Otterbein Procede de traitement d'un dommage a l'adn
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
ES2981406T3 (es) 2013-03-15 2024-10-08 Mallinckrodt Pharmaceuticals Ireland Ltd Administración y monitorización de óxido nítrico en fluidos ex vivo
TW201618795A (zh) 2014-04-15 2016-06-01 波泰里斯股份有限公司 用以改良器官功能及延長器官移植物壽命之系統及方法
EP4512819A3 (fr) 2015-08-12 2025-08-06 The General Hospital Corporation Compositions et procédés qui favorisent la réponse à l'hypoxie ou à l'hypoxie pour le traitement et la prévention d'un dysfonctionnement mitochondrial et de troubles du stress oxydatif
CN105288599A (zh) * 2015-10-22 2016-02-03 徐州医学院 血红素氧化酶-2在制备抑制器官移植免疫排斥制剂中的应用
KR20240142604A (ko) * 2017-08-25 2024-09-30 말린크로트 파마슈티칼스 아일랜드 리미티드 기관 생존력을 개선시키는 방법
EP3524290A1 (fr) 2018-02-09 2019-08-14 Julius-Maximilians-Universitaet Wuerzburg Procédé et système de surveillance de monoxyde de carbone (co) pour administrer des fluides ex vivo
CN116076484A (zh) * 2022-11-30 2023-05-09 武汉大学 一种修复肾脏损伤的低温携氧机械灌注液及其应用

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053590A (en) * 1975-02-27 1977-10-11 Alza Corporation Compositions of matter comprising macromolecular hemoglobin
US4264739A (en) * 1979-01-05 1981-04-28 Merck & Co., Inc. Sparger for cell culture system
JPS5679957A (en) 1979-12-05 1981-06-30 Sogo Seibutsu Igaku Kenkyusho:Kk Erucinia enterocolitica polysaccharide sensitizing blood cell and method of detecting erucinia enterocolitica polysaccharide antibody using this
US5240912A (en) * 1983-05-09 1993-08-31 Todaro George J Transforming growth factor (TGF) peptides
US5084380A (en) * 1985-01-29 1992-01-28 Applied Biotechnology Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
CN85202057U (zh) * 1985-05-31 1986-09-10 南京低压阀门厂 电热丝预热凹槽式燃油系统
US5449665A (en) * 1985-09-24 1995-09-12 Item Development Aktiebolag Continuous intravenous infusion of adenosine to human patients undergoing percutaneous transluminal angioplasty
DE3739650C1 (de) * 1987-11-23 1989-05-24 Immuno Ag Fermenter zum Zuechten von Zellkulturen
DE3928144A1 (de) * 1989-08-25 1991-02-28 Hoechst Ag Zyklische pyridin-2,4- und -2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
US5180366A (en) * 1990-10-10 1993-01-19 Woods W T Apparatus and method for angioplasty and for preventing re-stenosis
US5792325A (en) * 1990-11-15 1998-08-11 Richardson, Jr.; William H. Electric arc material processing system
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5396882A (en) 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
US5293875A (en) * 1992-06-16 1994-03-15 Natus Medical Incorporated In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods
NZ262679A (en) * 1993-02-22 1997-08-22 Vivorx Pharmaceuticals Inc Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell
AU6523194A (en) * 1993-03-26 1994-10-24 Biorelease Technologies, Inc. Compositions including heme-containing proteins and methods relating thereto
US5763431A (en) * 1993-08-20 1998-06-09 Jackson; Meyer B. Method for regulating neuropeptide hormone secretion
DE4421433C1 (de) * 1994-06-18 1995-06-08 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells
US6066333A (en) * 1994-09-22 2000-05-23 William Harvey Research Limited Pharmaceutical control of inflammation
US5664563A (en) * 1994-12-09 1997-09-09 Cardiopulmonary Corporation Pneumatic system
US5914316A (en) * 1994-12-16 1999-06-22 Washington University Method of inhibiting intimal hyperplasia
US6063407A (en) 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5712293A (en) * 1995-06-07 1998-01-27 Sepracor, Inc. Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride
FR2735382B1 (fr) * 1995-06-15 1997-07-25 Air Liquide Installation de production de monoxyde de carbone incorporant une unite de separation cryogenique
JP3195363B2 (ja) * 1995-06-30 2001-08-06 ザイモジェネティクス，インコーポレイティド Ｐｄｇｆアンタゴニストとしての４−〔２−（ｎ−２−カルボキサミドインドール）アミノエチル〕ベンゼンスルホンアミドまたはスルホニル尿素
ES2267141T3 (es) * 1996-04-05 2007-03-01 The General Hospital Corporation Tratamiento de una hemoglobinopatia.
US6069132A (en) * 1996-08-14 2000-05-30 Revanker; Ganapathi R. Phosphazole compounds
WO1998008523A1 (fr) 1996-08-27 1998-03-05 Messer Griesheim Gmbh Medicament contenant de l'hydrogene
US6316403B1 (en) * 1996-09-27 2001-11-13 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
ATE358492T1 (de) * 1996-09-27 2007-04-15 Univ Columbia Behandlung einer ischämischen störung und zur verbesserung des infarktergebnis
US6315995B1 (en) 1996-09-27 2001-11-13 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
US8128963B2 (en) * 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US5869538A (en) * 1996-11-26 1999-02-09 Research Foundation Of State University Of New York Method for enhancing transport of gases to tissues
FR2757259B1 (fr) * 1996-12-18 1999-03-05 Valeo Thermique Moteur Sa Ailette metallique perfectionnee pour echangeur de chaleur, notamment pour vehicule automobile
US5912019A (en) * 1997-02-07 1999-06-15 Musc Foundation For Research Development Compounds for reducing ischemia/reperfusion injury
TR200101502T2 (tr) 1998-03-16 2002-06-21 Celgene Corporation 2-(2,6-dioksopiperidin-3-il) izoindolin türevleri, bunların hazırlanması ve enflamatuar sitokinlerin inhibitörleri olarak kullanımı
US6203991B1 (en) * 1998-08-21 2001-03-20 The Regents Of The University Of Michigan Inhibition of smooth muscle cell migration by heme oxygenase I
US20050250688A1 (en) * 1999-04-01 2005-11-10 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
US7632803B2 (en) * 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US6558825B1 (en) * 2000-05-12 2003-05-06 Reveo, Inc. Fuel containment and recycling system
FR2812197B1 (fr) 2000-07-27 2003-01-03 Air Liquide Sante Int Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches
FR2816212A1 (fr) 2000-11-03 2002-05-10 Air Liquide Sante Int Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire
BR0208012A (pt) * 2001-03-20 2004-03-02 Glaxo Group Ltd Usos de pelo menos duas drogas e um propelente hfa e de pelo menos uma composição farmaceêutica, e, inalador acondicionado para tratar asma
US20030068387A1 (en) * 2001-03-30 2003-04-10 Roland Buelow Carbon monoxide generating compounds for treatment of vascular, inflammatory and immune disorders
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
EP1395241B9 (fr) * 2001-05-25 2005-06-15 Medtronic, Inc. Dispositif medical implantable equipe d'un systeme de liberation controlee d'agents gazeux
MXPA03012031A (es) 2001-06-21 2005-07-01 Univ Yale El monoxido de carbono mejoraresultados en transplantes de tejido y organo y suprime apoptosis.
NZ534912A (en) * 2002-02-04 2007-08-31 Alfama Investigacao E Desenvol supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative
BRPI0307673A2 (pt) * 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
RS91004A (sr) * 2002-04-15 2007-02-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education, Postupci za lečenje ileusa
WO2003088748A1 (fr) * 2002-04-15 2003-10-30 Beth Israel Deaconess Medical Center Utilisation d'heme-oxygenase-1 et produits de degradation d'heme
EP1499328B1 (fr) * 2002-04-15 2015-09-16 University of Pittsburgh - Of the Commonwealth System of Higher Education Methodes de traitement de l'enterocolite necrosante neonatale
JP4549847B2 (ja) * 2002-05-17 2010-09-22 イエール ユニバーシティ 肝炎の治療方法
UA87438C2 (ru) * 2002-06-05 2009-07-27 Йельский Университет Способы лечения или профилактики рака, способ проведения хирургической операции по удалению рака и применения монооксида углерода
CN1674942A (zh) * 2002-06-21 2005-09-28 联邦高等教育系统匹兹堡大学 氧化氮、血红素加氧酶－1和血红素降解产物的药学用途
PL377733A1 (pl) * 2002-11-07 2006-02-06 University Of Pittsburgh Of The Commonwealth System Of Higher Education Leczenie wstrząsu krwotocznego
WO2005077005A2 (fr) * 2004-02-04 2005-08-25 The General Hospital Corporation Amelioration de l'efficacite d'un gaz therapeutique inhale

Also Published As

Publication number Publication date
WO2003000114A3 (fr) 2003-04-10
CZ20033448A3 (cs) 2004-05-12
HUP0400371A3 (en) 2010-06-28
EP1404811A2 (fr) 2004-04-07
SI1404811T1 (sl) 2009-04-30
WO2003000114A2 (fr) 2003-01-03
NO20035637L (no) 2004-02-17
CN100502650C (zh) 2009-06-24
HK1067380A1 (en) 2005-04-08
EP2033514A3 (fr) 2009-04-29
EP1404811B1 (fr) 2008-11-12
JP2005500875A (ja) 2005-01-13
US7238469B2 (en) 2007-07-03
EP2033514A2 (fr) 2009-03-11
AU2002318377B2 (en) 2008-06-19
US20070202083A1 (en) 2007-08-30
DK1404811T3 (da) 2009-03-02
NZ562962A (en) 2009-08-28
CY1108798T1 (el) 2014-04-09
ATE413883T1 (de) 2008-11-15
JP4521183B2 (ja) 2010-08-11
EP1404811A4 (fr) 2006-08-09
AU2008221551A1 (en) 2008-10-09
SG147305A1 (en) 2008-11-28
BR0210599A (pt) 2004-07-20
US20030039638A1 (en) 2003-02-27
KR20040032115A (ko) 2004-04-14
PT1404811E (pt) 2009-01-22
HUP0400371A2 (hu) 2004-08-30
NO20035637D0 (no) 2003-12-17
SK15942003A3 (sk) 2004-08-03
MXPA03012031A (es) 2005-07-01
WO2003000114A9 (fr) 2004-05-21
CA2451266A1 (fr) 2003-01-03
CN1545548A (zh) 2004-11-10
DE60229848D1 (de) 2008-12-24
ES2316583T3 (es) 2009-04-16
PL367544A1 (en) 2005-02-21

Similar Documents

Publication Publication Date Title
BG108492A (bg) Използване на въглероден окис за подобряване на резултатите при трансплантация на тъкани и органи и потискане на апоптозата
MX2007005200A (es) Plaquetas a partir de celulas germinales.
EA200600076A1 (ru) Композиции и способы увеличения активности теломеразы
NO20051030L (no) Funksjonelle kardiomyocytter fra humane embryonale stamceller
CR7786A (es) Anticuerpos neutralizantes contra gdf-8 y el uso de los mismos
BR0214029A (pt) Métodos e composições para o uso de células estromais para suportar células tronco embriÈnicas e adultas
EA200100749A1 (ru) Синтетические пептиды, обладающие поверхностной активностью, и их применение для приготовления синтетического сурфактанта
DE602004031134D1 (de) Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
DE60118604D1 (de) Photosensibilisator-enthaltende lagerungslösung zur inaktivierung von biologischen verunreinigungen
AU8524901A (en) Membrane penetrating peptides and uses thereof
CY1118073T1 (el) Συνθεσεις και μεθοδοι για την αυξηση της δρασης της τελομερασης
ES2186803T3 (es) Peptidos tio-sustituidos como inhibidores de metaloproteinasas y de la liberacion de tnf.
DE60021381D1 (de) Chinonverbindungen zur behandlung von krankheiten
DK1526840T3 (da) Nanopartikler til DNA administration til et målorgan
EA200600468A1 (ru) Биполярные транс-каротиноидные соли и их применение
ATE521696T1 (de) Verfahren zur herstellung von zelltransplantaten
DE60327710D1 (de) Modifizierte zytokine für krebs therapie
CY1108048T1 (el) Συνθεση σπογγοσινης
DE60132466D1 (de) Verfahren zur kultivierung von menschlichen lungenmastzellen und deren anwendungen
EA200701598A1 (ru) Способ и композиция для восстановления эпителиальных и других клеток и тканей
DE60028750D1 (de) Verwendung von tagatose zur verbesserung wichtiger blutfaktoren
DE50004024D1 (de) Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation
ATE222497T1 (de) Methode zur steigerung der überlebung transplantierter zellen
RU2009123679A (ru) Способ восстановления естественной окраски кожи лица у трупов
UA39614A (uk) Спосіб корекції функціонального стану міокарда у лабораторних тварин пізнього онтогенезу