BG108498A - New derivatives of oxazolidinones as antibacterial agents - Google Patents

New derivatives of oxazolidinones as antibacterial agents

Info

Publication number
BG108498A
BG108498A BG108498A BG10849803A BG108498A BG 108498 A BG108498 A BG 108498A BG 108498 A BG108498 A BG 108498A BG 10849803 A BG10849803 A BG 10849803A BG 108498 A BG108498 A BG 108498A
Authority
BG
Bulgaria
Prior art keywords
oxazolidinones
antibacterial agents
new derivatives
general formula
new
Prior art date
Application number
BG108498A
Other languages
Bulgarian (bg)
English (en)
Inventor
Marisabel Mancini
Juan CLODET
Jose Rodriguez
Castillo Juan Del
Original Assignee
Laboratorios Vita, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Vita, S.A. filed Critical Laboratorios Vita, S.A.
Publication of BG108498A publication Critical patent/BG108498A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG108498A 2001-06-27 2003-12-22 New derivatives of oxazolidinones as antibacterial agents BG108498A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101559A ES2186550B2 (es) 2001-06-27 2001-06-27 Nuevos derivados de oxazolidinonas como antibacterianos.

Publications (1)

Publication Number Publication Date
BG108498A true BG108498A (en) 2005-03-31

Family

ID=8498288

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108498A BG108498A (en) 2001-06-27 2003-12-22 New derivatives of oxazolidinones as antibacterial agents

Country Status (29)

Country Link
US (1) US20040147545A1 (is)
EP (1) EP1401834A1 (is)
JP (1) JP2004521147A (is)
KR (1) KR20040030712A (is)
CN (1) CN1520412A (is)
AP (1) AP2003002942A0 (is)
AR (1) AR035254A1 (is)
BG (1) BG108498A (is)
BR (1) BR0210667A (is)
CA (1) CA2450982A1 (is)
CO (1) CO5540387A2 (is)
CR (1) CR7195A (is)
CZ (1) CZ2004101A3 (is)
EA (1) EA200400086A1 (is)
EE (1) EE200400004A (is)
ES (1) ES2186550B2 (is)
HR (1) HRP20031063A2 (is)
HU (1) HUP0400370A2 (is)
IL (1) IL159434A0 (is)
IS (1) IS7088A (is)
MA (1) MA27046A1 (is)
MX (1) MXPA04000185A (is)
NO (1) NO20035791L (is)
NZ (1) NZ530206A (is)
OA (1) OA12639A (is)
PE (1) PE20030134A1 (is)
PL (1) PL365476A1 (is)
SK (1) SK572004A3 (is)
WO (1) WO2003002560A1 (is)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
NZ543757A (en) * 2003-04-30 2009-02-28 Morphochem Ag Komb Chemie Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005051933A1 (en) * 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby
AU2004299278C9 (en) * 2003-12-18 2013-10-24 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
EP1557416A1 (en) * 2004-01-23 2005-07-27 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
US20060105941A1 (en) * 2004-11-12 2006-05-18 Allergan, Inc. Mixed antibiotic codrugs
KR20080110877A (ko) 2006-03-31 2008-12-19 재단법인 이쯔우 연구소 헤테로환을 갖는 신규 화합물
WO2009044777A1 (ja) 2007-10-02 2009-04-09 Research Foundation Itsuu Laboratory ７員ヘテロ環を有するオキサゾリジノン誘導体
CA2723232C (en) * 2008-05-09 2016-08-02 Actelion Pharmaceuticals Ltd 5-hydroxymethyl-oxazolidin-2-one derivatives for treating bacterial intestinal diseases
ES2726828T3 (es) 2013-05-28 2019-10-09 Morphochem Gmbh Administración de antibacterianos híbridos de oxazolidinona-quinolona
RU2675847C2 (ru) 2013-05-28 2018-12-25 Морфохем Акциенгезельшафт Фюр Комбинаторише Хеми Комбинированные терапевтические средства, содержащие оксазолидинон-хинолоны, предназначенные для лечения бактериальных инфекций
CN107286111B (zh) * 2016-03-30 2020-06-19 广东赛法洛药业有限公司 一种噁唑烷酮化合物的制备方法
CN107286182A (zh) * 2016-04-12 2017-10-24 李靖 新型噁唑烷酮‑氟喹诺酮衍生物及用途
US10087171B2 (en) 2016-12-19 2018-10-02 Actelion Pharmaceuticals Ltd Crystalline forms of cadazolid
GB201708606D0 (en) 2017-05-30 2017-07-12 King S College London Antibiotic resistance breakers
WO2019106693A1 (en) * 2017-11-29 2019-06-06 Bugworks Research India Pvt Ltd Anti-bacterial heterocyclic compounds and their synthesis
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
CN117567455A (zh) * 2019-12-11 2024-02-20 华创合成制药股份有限公司 一种新型噁唑烷酮类化合物及其合成方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE444566B (sv) * 1977-09-20 1986-04-21 Bellon Labor Sa Roger 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav
DE69019859T2 (de) * 1989-03-30 1995-10-05 Wakunaga Seiyaku Kk Chinolon-Derivate und deren Salze, Verfahren zu deren Herstellung und diese enthaltende antibakterielle Wirkstoffe.
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
JP3933198B2 (ja) * 1994-10-26 2007-06-20 ファルマシア・アンド・アップジョン・カンパニー フェニルオキサゾリジノン抗菌剤
CA2245179A1 (en) * 1996-01-31 1997-08-07 Ube Industries Limited Remedies or preventives for aids
ES2166073T3 (es) * 1996-04-11 2002-04-01 Upjohn Co Procedimiento para preparar oxazolidinonas.
GB9614236D0 (en) * 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
NZ530206A (en) 2005-07-29
CO5540387A2 (es) 2005-07-29
HRP20031063A2 (en) 2004-04-30
SK572004A3 (en) 2004-08-03
MA27046A1 (fr) 2004-12-20
IS7088A (is) 2003-12-22
PL365476A1 (en) 2005-01-10
US20040147545A1 (en) 2004-07-29
NO20035791L (no) 2004-02-19
PE20030134A1 (es) 2003-04-04
OA12639A (en) 2006-06-15
ES2186550B2 (es) 2003-11-16
CZ2004101A3 (cs) 2004-07-14
JP2004521147A (ja) 2004-07-15
AP2003002942A0 (en) 2003-12-24
MXPA04000185A (es) 2004-03-18
HUP0400370A2 (hu) 2004-08-30
CR7195A (es) 2004-03-05
WO2003002560A1 (en) 2003-01-09
EA200400086A1 (ru) 2004-06-24
CA2450982A1 (en) 2003-01-09
ES2186550A1 (es) 2003-05-01
CN1520412A (zh) 2004-08-11
EP1401834A1 (en) 2004-03-31
IL159434A0 (en) 2004-06-01
EE200400004A (et) 2004-02-16
BR0210667A (pt) 2004-10-05
KR20040030712A (ko) 2004-04-09
AR035254A1 (es) 2004-05-05

Similar Documents

Publication Publication Date Title
BG108498A (en) New derivatives of oxazolidinones as antibacterial agents
TW200502230A (en) Dual nk1/nk3 derivatives
EG25017A (en) N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobials.
UA94901C2 (ru) Антибактериальные производные пиперидина
TW200500358A (en) Compounds
GB0022438D0 (en) Organic Compounds
MX2007000505A (es) Derivados de oxindol sustituidos y medicamentos que contienen los mismos.
MY135850A (en) Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
GEP20094834B (en) Macrolides, pharmaceutical compositions containing them and their use for treatment of bacterial infections
SG162614A1 (en) Bicyclic 6-alkylidene-penems as beta-lactamases inhibitors
GEP20084437B (en) Novel lincomycin derivatives possessing antimicrobial activity
GEP20084306B (en) Antibacterial indolone oxazolidinones, intermediates for their preparation and pharmaceutical compositions containing them
SE0203070D0 (en) Novel compounds
WO2005054234A8 (en) Substituted piperidino phenyloxazolidinones having antimicriobial activity with improved in vivo efficacy
UA83266C2 (en) Oxazole derivatives of tetracyclines
CA2386685A1 (en) Use of pleuromutilin derivatives for transdermal treatment of bacterial diseases
WO2004043928A3 (en) N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobial agents
TW200640911A (en) Novel, long acting betamimetics for the treatment of respiratory diseases
TW200640465A (en) New pharmaceutically active compounds for the treatment of respiratory diseases
ATE440835T1 (de) Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
GB0012795D0 (en) Organic compounds
MX2007008585A (es) Compuestos peptidicos.
DE60208541D1 (de) Antibakterielle mittel
MXPA04006600A (es) Dihidrotiazina-y dihidrotiopiran-oxazolidinonas antimicrobianas.
WO2007079173A3 (en) Novel 2-heteroaryloxy-phenol derivatives as antibacterial agents