BG47035A3 - Метод за получаване на монохидрат на бета-лактамов антибиотик 1-карбацефалоспорин - Google Patents

Метод за получаване на монохидрат на бета-лактамов антибиотик 1-карбацефалоспорин

Info

Publication number
BG47035A3
BG47035A3 BG085593A BG8559388A BG47035A3 BG 47035 A3 BG47035 A3 BG 47035A3 BG 085593 A BG085593 A BG 085593A BG 8559388 A BG8559388 A BG 8559388A BG 47035 A3 BG47035 A3 BG 47035A3
Authority
BG
Bulgaria
Prior art keywords
monohydrate
carbacephalosporin
beta
obtaining
lactam antibiotic
Prior art date
Application number
BG085593A
Other languages
Bulgarian (bg)
English (en)
Inventor
John Brennan
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG47035A3 publication Critical patent/BG47035A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG085593A 1987-10-07 1988-10-04 Метод за получаване на монохидрат на бета-лактамов антибиотик 1-карбацефалоспорин BG47035A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10576287A 1987-10-07 1987-10-07

Publications (1)

Publication Number Publication Date
BG47035A3 true BG47035A3 (bg) 1990-04-16

Family

ID=22307652

Family Applications (1)

Application Number Title Priority Date Filing Date
BG085593A BG47035A3 (bg) 1987-10-07 1988-10-04 Метод за получаване на монохидрат на бета-лактамов антибиотик 1-карбацефалоспорин

Country Status (24)

Country Link
EP (1) EP0311365A1 (cs)
JP (1) JPH02270871A (cs)
KR (1) KR890006643A (cs)
CN (1) CN1032442A (cs)
AU (1) AU605635B2 (cs)
BG (1) BG47035A3 (cs)
CS (1) CS270593B2 (cs)
DD (1) DD280112A5 (cs)
DK (1) DK553888A (cs)
FI (1) FI884555L (cs)
HU (1) HU205112B (cs)
IL (1) IL87904A0 (cs)
MX (1) MX13276A (cs)
MY (1) MY103554A (cs)
NO (1) NO884417L (cs)
NZ (1) NZ226451A (cs)
OA (1) OA09017A (cs)
PH (1) PH26811A (cs)
PL (2) PL163113B1 (cs)
PT (1) PT88663B (cs)
RO (2) RO105809B1 (cs)
RU (1) RU1776260C (cs)
YU (1) YU46700B (cs)
ZA (1) ZA887408B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate
NZ242556A (en) * 1991-05-10 1993-08-26 Lilly Co Eli Preparation of carbacephem derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate

Also Published As

Publication number Publication date
CS666588A2 (en) 1989-11-14
NO884417D0 (no) 1988-10-05
ZA887408B (en) 1990-06-27
AU605635B2 (en) 1991-01-17
HUT48883A (en) 1989-07-28
PT88663A (pt) 1989-07-31
RU1776260C (ru) 1992-11-15
MY103554A (en) 1993-07-31
PL275092A1 (en) 1989-05-16
CS270593B2 (en) 1990-07-12
RO102423B1 (en) 1992-08-01
HU205112B (en) 1992-03-30
DD280112A5 (de) 1990-06-27
NZ226451A (en) 1990-10-26
JPH02270871A (ja) 1990-11-05
CN1032442A (zh) 1989-04-19
DK553888D0 (da) 1988-10-04
NO884417L (no) 1989-04-10
OA09017A (fr) 1991-03-31
YU184688A (en) 1990-04-30
FI884555A7 (fi) 1989-04-08
FI884555L (fi) 1989-04-08
AU2337188A (en) 1989-04-13
EP0311365A1 (en) 1989-04-12
RO105809B1 (ro) 1992-12-30
PL159766B1 (pl) 1993-01-29
FI884555A0 (fi) 1988-10-04
PH26811A (en) 1992-11-05
KR890006643A (ko) 1989-06-15
PL163113B1 (pl) 1994-02-28
PT88663B (pt) 1993-10-29
DK553888A (da) 1989-04-08
MX13276A (es) 1993-11-01
YU46700B (sh) 1994-04-05
IL87904A0 (en) 1989-03-31

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