BG60436B2 - 1-окса-2-оксо-8-азаспиро(4,5)декани,фармацевтични състави, които ги съдържат,и метод за получаването им - Google Patents

1-окса-2-оксо-8-азаспиро(4,5)декани,фармацевтични състави, които ги съдържат,и метод за получаването им Download PDF

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Publication number
BG60436B2
BG60436B2 BG098261A BG9826193A BG60436B2 BG 60436 B2 BG60436 B2 BG 60436B2 BG 098261 A BG098261 A BG 098261A BG 9826193 A BG9826193 A BG 9826193A BG 60436 B2 BG60436 B2 BG 60436B2
Authority
BG
Bulgaria
Prior art keywords
oxo
oxa
fluorophenyl
decane
butyl
Prior art date
Application number
BG098261A
Other languages
Bulgarian (bg)
English (en)
Inventor
Edit Toth
Jozsef Toerley
Laszlo Szporny
Bela Kiss
Egon Karpati
Eva Palosi
Dora Groo
Istvan Laszlovszky
Zsolt Szombathelyi
Adam Sarkadi
Aniko Gere
Katalin Csomor
Mihaly Bodo
Judit Laszy
Zsolt Szentirmay
Original Assignee
Richter Gedeon Vegyeszeti Gyar Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar Rt. filed Critical Richter Gedeon Vegyeszeti Gyar Rt.
Publication of BG60436B2 publication Critical patent/BG60436B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
BG098261A 1989-08-10 1993-12-02 1-окса-2-оксо-8-азаспиро(4,5)декани,фармацевтични състави, които ги съдържат,и метод за получаването им BG60436B2 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU894095A HU204530B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
SG96294A SG96294G (en) 1989-08-10 1994-07-16 1-oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
BG60436B2 true BG60436B2 (bg) 1995-03-31

Family

ID=26317733

Family Applications (1)

Application Number Title Priority Date Filing Date
BG098261A BG60436B2 (bg) 1989-08-10 1993-12-02 1-окса-2-оксо-8-азаспиро(4,5)декани,фармацевтични състави, които ги съдържат,и метод за получаването им

Country Status (23)

Country Link
US (1) US5118687A (de)
EP (1) EP0414421B1 (de)
JP (1) JPH0749431B2 (de)
KR (1) KR940006635B1 (de)
AT (1) ATE103920T1 (de)
AU (1) AU622039B2 (de)
BG (1) BG60436B2 (de)
DD (1) DD299429A5 (de)
DE (1) DE69007904T2 (de)
DK (1) DK0414421T3 (de)
ES (1) ES2052180T3 (de)
FI (1) FI93455C (de)
HK (1) HK145994A (de)
HR (1) HRP920778A2 (de)
HU (2) HU204530B (de)
IE (1) IE64911B1 (de)
IL (1) IL95320A (de)
NO (1) NO177962C (de)
NZ (1) NZ234848A (de)
PL (3) PL163593B1 (de)
SG (1) SG96294G (de)
SI (1) SI9011538A (de)
ZA (1) ZA906302B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
EP1223990B1 (de) * 1999-10-15 2004-07-28 Genetics Institute, LLC Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
RU2257202C2 (ru) * 2000-12-01 2005-07-27 Соболев Дмитрий Владимирович Натриевая соль поли(парадигидрокси- парафенилен)тиосульфокислоты в качестве регулятора метаболизма клеток и антигипоксанта, фармацевтическая композиция на ее основе
KR20020091462A (ko) * 2001-05-30 2002-12-06 삼성광주전자 주식회사 원료 굳음 방지기능을 갖는 자동판매기 및 그 제어방법
GB201416346D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR96352E (fr) * 1967-12-29 1972-06-16 Science Union & Cie Nouveaux dérives du spiro (4,5) decane et leur procédé de préparation.
BE790675A (fr) * 1971-10-29 1973-04-27 Science Union & Cie Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
HU204529B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물

Also Published As

Publication number Publication date
FI93455B (fi) 1994-12-30
DK0414421T3 (da) 1994-05-16
DE69007904D1 (de) 1994-05-11
IE902884A1 (en) 1991-02-27
SI9011538A (sl) 1998-08-31
HU210072A9 (en) 1995-02-28
NO903512L (no) 1991-02-11
KR910004632A (ko) 1991-03-29
PL286440A1 (en) 1992-01-27
JPH0749431B2 (ja) 1995-05-31
HU204530B (en) 1992-01-28
HK145994A (en) 1994-12-30
NO177962C (no) 1995-12-27
PL291702A1 (en) 1992-05-04
ES2052180T3 (es) 1994-07-01
PL163431B1 (pl) 1994-03-31
NZ234848A (en) 1992-03-26
KR940006635B1 (ko) 1994-07-23
IL95320A0 (en) 1991-06-30
AU622039B2 (en) 1992-03-26
NO177962B (no) 1995-09-18
JPH0377884A (ja) 1991-04-03
FI93455C (fi) 1995-04-10
HRP920778A2 (en) 1998-02-28
HUT55786A (en) 1991-06-28
EP0414421B1 (de) 1994-04-06
DD299429A5 (de) 1992-04-16
SG96294G (en) 1994-10-28
DE69007904T2 (de) 1994-07-21
AU6080790A (en) 1991-02-14
FI903972A0 (fi) 1990-08-10
PL163593B1 (en) 1994-04-29
EP0414421A2 (de) 1991-02-27
ATE103920T1 (de) 1994-04-15
PL163370B1 (pl) 1994-03-31
IL95320A (en) 1994-01-25
NO903512D0 (no) 1990-08-09
ZA906302B (en) 1991-06-26
IE64911B1 (en) 1995-09-20
PL291701A1 (en) 1992-05-04
US5118687A (en) 1992-06-02
EP0414421A3 (en) 1991-07-24

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