BG60680B1 - Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им - Google Patents

Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им Download PDF

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Publication number
BG60680B1
BG60680B1 BG96487A BG9648792A BG60680B1 BG 60680 B1 BG60680 B1 BG 60680B1 BG 96487 A BG96487 A BG 96487A BG 9648792 A BG9648792 A BG 9648792A BG 60680 B1 BG60680 B1 BG 60680B1
Authority
BG
Bulgaria
Prior art keywords
general formula
formula
compounds
radical
compound
Prior art date
Application number
BG96487A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG96487A (bg
Inventor
Paule Bonnet
Remi Delansorne
Maurice Faure
Michel Lanquetin
Serge Zunino
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of BG96487A publication Critical patent/BG96487A/bg
Publication of BG60680B1 publication Critical patent/BG60680B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG96487A 1990-10-17 1992-06-16 Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им BG60680B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR909012562A FR2668150B1 (fr) 1990-10-17 1990-10-17 Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
PCT/FR1991/000811 WO1992006977A1 (fr) 1990-10-17 1991-10-17 NOUVEAUX DERIVES p-SUBSTITUES DE PHENYL 4-OXYBUTANE AMINE, LEURS PROCEDES DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES EN RENFERMANT

Publications (2)

Publication Number Publication Date
BG96487A BG96487A (bg) 1993-12-24
BG60680B1 true BG60680B1 (bg) 1995-12-29

Family

ID=9401134

Family Applications (1)

Application Number Title Priority Date Filing Date
BG96487A BG60680B1 (bg) 1990-10-17 1992-06-16 Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им

Country Status (23)

Country Link
US (1) US5461059A (cs)
EP (1) EP0505543A1 (cs)
JP (1) JPH05503298A (cs)
KR (1) KR927003589A (cs)
AP (1) AP282A (cs)
BG (1) BG60680B1 (cs)
BR (1) BR9106188A (cs)
CA (1) CA2071911A1 (cs)
CZ (1) CZ182292A3 (cs)
FI (1) FI922773L (cs)
FR (2) FR2668150B1 (cs)
HU (1) HUT61297A (cs)
IE (1) IE913636A1 (cs)
IL (1) IL99776A0 (cs)
MA (1) MA22321A1 (cs)
NO (1) NO922358L (cs)
NZ (1) NZ240274A (cs)
OA (1) OA09835A (cs)
PL (2) PL169022B1 (cs)
PT (1) PT99266A (cs)
RO (1) RO108241B1 (cs)
WO (1) WO1992006977A1 (cs)
ZA (1) ZA918282B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
KR960702445A (ko) * 1993-05-20 1996-04-27 간자와 무츠오 1-(2-벤조이미다졸일)-1, 5- 디아자시클로옥탄 유도체(1-(2-benzimidazo-lyl)-1,5-diazacyclooctane compounds)
ES2072193B1 (es) * 1993-05-21 1996-02-16 Espanola Prod Quimicos Nuevos derivados del1-fenilmetil bencimidazol piperacinas.
US5691323A (en) * 1995-05-12 1997-11-25 Merck & Co., Inc. Muscarine antagonists
FR2727865B1 (fr) * 1994-12-08 1997-07-18 Esteve Labor Dr Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
JP2000507579A (ja) * 1996-04-03 2000-06-20 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質トランスフェラーゼ阻害剤
AU2001268958B2 (en) * 2000-07-04 2006-03-09 Novo Nordisk A/S Heterocyclic compounds, which are inhibitors of the enzyme dpp-iv
WO2004009091A1 (en) * 2002-06-17 2004-01-29 Glaxo Group Limited Purine derivatives as liver x receptor agonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297097A (cs) * 1962-08-31
US3161645A (en) * 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
JPS5879983A (ja) * 1981-11-06 1983-05-13 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
MY106964A (en) * 1988-04-28 1995-08-30 Schering Corp Fused polycyclic compounds, compositions, methods of manufacture, and their use as paf antagonists, antihistamines and/or antiinflammatory agents.
US4908372A (en) * 1988-10-13 1990-03-13 Merrell Dow Pharmaceuticals Inc. Antihistaminic piperidinyl benzimidazoles
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds

Also Published As

Publication number Publication date
KR927003589A (ko) 1992-12-18
FR2668150A1 (fr) 1992-04-24
IL99776A0 (en) 1992-08-18
US5461059A (en) 1995-10-24
HUT61297A (en) 1992-12-28
PT99266A (pt) 1992-08-31
BR9106188A (pt) 1993-03-16
WO1992006977A1 (fr) 1992-04-30
NO922358L (no) 1992-08-11
HU9202176D0 (en) 1992-10-28
FI922773A7 (fi) 1992-06-16
FR2668150B1 (fr) 1994-11-18
CA2071911A1 (fr) 1992-04-18
JPH05503298A (ja) 1993-06-03
PL169452B1 (pl) 1996-07-31
NZ240274A (en) 1995-07-26
AP9100328A0 (en) 1991-10-31
FR2670783B1 (fr) 1994-11-18
IE913636A1 (en) 1992-04-22
FI922773A0 (fi) 1992-06-16
ZA918282B (en) 1992-07-29
EP0505543A1 (fr) 1992-09-30
RO108241B1 (ro) 1994-03-31
PL169022B1 (pl) 1996-05-31
FR2670783A1 (fr) 1992-06-26
NO922358D0 (no) 1992-06-16
OA09835A (fr) 1994-08-15
MA22321A1 (fr) 1992-07-01
FI922773L (fi) 1992-06-16
BG96487A (bg) 1993-12-24
AP282A (en) 1993-09-08
CZ182292A3 (en) 1993-01-13

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