BG62777B1 - Нов синтетичен пептид, съдържащо пептида белодробно повърхностно активно вещество и лекарствено средство за лечение на дихателна недостатъчност - Google Patents

Нов синтетичен пептид, съдържащо пептида белодробно повърхностно активно вещество и лекарствено средство за лечение на дихателна недостатъчност Download PDF

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Publication number
BG62777B1
BG62777B1 BG100554A BG10055496A BG62777B1 BG 62777 B1 BG62777 B1 BG 62777B1 BG 100554 A BG100554 A BG 100554A BG 10055496 A BG10055496 A BG 10055496A BG 62777 B1 BG62777 B1 BG 62777B1
Authority
BG
Bulgaria
Prior art keywords
peptide
valine
surfactant
leucine
sequence
Prior art date
Application number
BG100554A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100554A (bg
Inventor
Tsunetomo Takei
Eiji Ohtsubo
Hirosi Ohkawa
Original Assignee
Mitsubishi-Tokyo Pharmaceuticals, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi-Tokyo Pharmaceuticals, Inc filed Critical Mitsubishi-Tokyo Pharmaceuticals, Inc
Publication of BG100554A publication Critical patent/BG100554A/bg
Publication of BG62777B1 publication Critical patent/BG62777B1/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
BG100554A 1993-12-08 1996-05-02 Нов синтетичен пептид, съдържащо пептида белодробно повърхностно активно вещество и лекарствено средство за лечение на дихателна недостатъчност BG62777B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30765793 1993-12-08
PCT/JP1994/002057 WO1995015980A1 (en) 1993-12-08 1994-12-07 Novel synthetic peptide, lung surfactant containing the same, and remedy for respiratory distress syndrome

Publications (2)

Publication Number Publication Date
BG100554A BG100554A (bg) 1996-12-31
BG62777B1 true BG62777B1 (bg) 2000-07-31

Family

ID=17971685

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100554A BG62777B1 (bg) 1993-12-08 1996-05-02 Нов синтетичен пептид, съдържащо пептида белодробно повърхностно активно вещество и лекарствено средство за лечение на дихателна недостатъчност

Country Status (22)

Country Link
US (1) US5827825A (de)
EP (1) EP0733645B1 (de)
JP (1) JP3644035B2 (de)
KR (1) KR100342806B1 (de)
CN (1) CN1057099C (de)
AT (1) ATE234865T1 (de)
AU (1) AU682738B2 (de)
BG (1) BG62777B1 (de)
CA (1) CA2178345A1 (de)
CZ (1) CZ162396A3 (de)
DE (1) DE69432313T2 (de)
DK (1) DK0733645T3 (de)
ES (1) ES2189825T3 (de)
FI (1) FI962355A0 (de)
HU (1) HU215933B (de)
NO (1) NO962403D0 (de)
NZ (1) NZ277095A (de)
PL (1) PL180020B1 (de)
PT (1) PT733645E (de)
RO (1) RO118298B1 (de)
SK (1) SK71496A3 (de)
WO (1) WO1995015980A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2576895A (en) * 1994-12-07 1996-06-26 Tokyo Tanabe Company Limited Intermediate for producing surfactant peptide
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
JPH11217397A (ja) * 1997-11-27 1999-08-10 Saburo Aimoto ペプチドチオールエステルの製造方法
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
BR9906091A (pt) * 1999-12-22 2002-06-04 Conselho Nacional Cnpq Usos de resina de troca aniÈnica (epm-7) como suporte sólido para a sìntese peptìdica e para cromatografia de afinidade
AU2002357168A1 (en) 2001-12-12 2003-07-09 Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
ATE376556T1 (de) * 2003-12-31 2007-11-15 Hoffmann La Roche Verfahren zur peptidsynthese unter verwendung einer reduzierten menge an entschützungsmittel
US8029815B2 (en) * 2004-04-28 2011-10-04 Elford Howard L Methods for treating or preventing restenosis and other vascular proliferative disorders
US7638493B2 (en) * 2004-04-29 2009-12-29 Sannamu Lee Artificial pulmonary surfactant compositions and use of the same
KR100635541B1 (ko) * 2004-10-12 2006-10-18 경북대학교 산학협력단 신규한 염증성 질환의 예방 또는 치료용 약학적 조성물
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
SI1841458T1 (sl) 2005-01-06 2012-04-30 Discovery Lab Inc Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije
WO2007084136A2 (en) * 2006-01-23 2007-07-26 Ony, Inc. Treatment of acute respiratory distress syndrome
EP2063903A1 (de) * 2006-09-19 2009-06-03 Discovery Laboratories, Inc. Lungentensidformulierungen und verfahren zur förderung von schleimbeseitigung
EP2022798A1 (de) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetische Lungensurfactant-Peptide
WO2009123119A1 (ja) 2008-04-02 2009-10-08 国立大学法人徳島大学 合成ペプチドを含有する抗原薬物ビークルとこれを用いる粘膜ワクチン
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988003170A1 (en) * 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
ATE163013T1 (de) * 1987-11-04 1998-02-15 Byk Gulden Lomberg Chem Fab Alveolare oberflächenaktive proteine
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
US5827825A (en) 1998-10-27
PL180020B1 (en) 2000-12-29
NZ277095A (en) 1997-09-22
JP3644035B2 (ja) 2005-04-27
ATE234865T1 (de) 2003-04-15
WO1995015980A1 (en) 1995-06-15
NO962403L (no) 1996-06-07
CZ162396A3 (en) 1996-10-16
FI962355L (fi) 1996-06-06
KR960706507A (ko) 1996-12-09
EP0733645A4 (de) 1998-12-09
HU9601563D0 (en) 1996-08-28
CN1057099C (zh) 2000-10-04
PT733645E (pt) 2003-07-31
NO962403D0 (no) 1996-06-07
DE69432313D1 (de) 2003-04-24
CN1136813A (zh) 1996-11-27
SK71496A3 (en) 1996-11-06
FI962355A7 (fi) 1996-06-06
ES2189825T3 (es) 2003-07-16
DE69432313T2 (de) 2003-10-16
KR100342806B1 (ko) 2002-11-29
RO118298B1 (ro) 2003-04-30
PL314872A1 (en) 1996-09-30
CA2178345A1 (en) 1995-06-15
FI962355A0 (fi) 1996-06-06
AU682738B2 (en) 1997-10-16
HU215933B (hu) 1999-03-29
BG100554A (bg) 1996-12-31
EP0733645A1 (de) 1996-09-25
HUT74880A (en) 1997-02-28
EP0733645B1 (de) 2003-03-19
AU1199295A (en) 1995-06-27
DK0733645T3 (da) 2003-07-14

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