BG98306A - Нови 4(5)-имидазоли,селективни инхибитори на ароматаза - Google Patents

Нови 4(5)-имидазоли,селективни инхибитори на ароматаза Download PDF

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Publication number
BG98306A
BG98306A BG98306A BG9830693A BG98306A BG 98306 A BG98306 A BG 98306A BG 98306 A BG98306 A BG 98306A BG 9830693 A BG9830693 A BG 9830693A BG 98306 A BG98306 A BG 98306A
Authority
BG
Bulgaria
Prior art keywords
hydrogen
compound
formula
solution
compounds
Prior art date
Application number
BG98306A
Other languages
Bulgarian (bg)
English (en)
Inventor
Arto Karjalainen
Marja-Liisa Soedervall
Arja Kalapudas
Reino Pelkonen
Aire Laine
Risto Lammintausta
Jarmo Salonen
Original Assignee
Orion- Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919113142A external-priority patent/GB9113142D0/en
Application filed by Orion- Yhtymae Oy filed Critical Orion- Yhtymae Oy
Publication of BG98306A publication Critical patent/BG98306A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG98306A 1991-06-18 1993-12-17 Нови 4(5)-имидазоли,селективни инхибитори на ароматаза BG98306A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919113142A GB9113142D0 (en) 1991-06-18 1991-06-18 New selective aromatase inhibiting 4(5)-imidazoles
GB919125924A GB9125924D0 (en) 1991-06-18 1991-12-05 Stereoisomers of an imidazole derivative
PCT/FI1992/000184 WO1992022537A1 (en) 1991-06-18 1992-06-12 New selective aromatase inhibiting 4(5)-imidazoles

Publications (1)

Publication Number Publication Date
BG98306A true BG98306A (bg) 1994-08-30

Family

ID=26299089

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98306A BG98306A (bg) 1991-06-18 1993-12-17 Нови 4(5)-имидазоли,селективни инхибитори на ароматаза

Country Status (25)

Country Link
US (1) US5559141A (lt)
EP (1) EP0589975A1 (lt)
JP (1) JPH06508119A (lt)
KR (1) KR940701386A (lt)
CN (1) CN1068819A (lt)
AU (1) AU665002B2 (lt)
BG (1) BG98306A (lt)
CA (1) CA2111469A1 (lt)
CZ (1) CZ280293A3 (lt)
FI (1) FI935658A0 (lt)
GB (1) GB9125924D0 (lt)
HR (1) HRP920170A2 (lt)
HU (1) HUT67325A (lt)
IE (1) IE921963A1 (lt)
IL (2) IL102216A (lt)
LT (1) LT3164B (lt)
LV (1) LV10093B (lt)
MX (1) MX9203000A (lt)
NO (1) NO934688D0 (lt)
NZ (1) NZ243139A (lt)
PT (1) PT100604A (lt)
SI (1) SI9200113A (lt)
SK (1) SK144393A3 (lt)
TW (1) TW206217B (lt)
WO (1) WO1992022537A1 (lt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2273704B (en) * 1992-12-16 1997-01-22 Orion Yhtymae Oy Triazolyl diaryl selective aromatase inhibiting compounds
SE9302333D0 (sv) * 1993-07-06 1993-07-06 Ab Astra New compounds
US6063930A (en) * 1996-04-03 2000-05-16 Merck & Co., Inc. Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
US6080870A (en) * 1996-04-03 2000-06-27 Merck & Co., Inc. Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors
JP2000504024A (ja) * 1996-04-03 2000-04-04 メルク エンド カンパニー インコーポレーテッド ファルネシル―タンパク質トランスフェラーゼ阻害剤
US6297239B1 (en) * 1997-10-08 2001-10-02 Merck & Co., Inc. Inhibitors of prenyl-protein transferase
KR20030031132A (ko) 2000-07-28 2003-04-18 스미또모 세이야꾸 가부시키가이샤 피롤 유도체
MXPA06003951A (es) 2003-10-07 2006-06-27 Renovis Inc Derivados de amida como ligandos del canal de ion y composiciones farmaceuticas y sus metodos de uso.
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
BRPI0606365A2 (pt) * 2005-02-28 2017-06-27 Renovis Inc composto ou um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo e estereoisômeros e tautômeros do mesmo, composição farmacêutica, métodos para prevenir, tratar, melhorar ou controlar uma doença ou condição e para preparar um composto, uso de um composto ou um sal, solvato ou composição farmaceuticamente aceitável do mesmo, método de tratamento de um mamífero, e, combinação
US7902247B2 (en) * 2008-01-09 2011-03-08 Allergan, Inc. Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors
KR20260006612A (ko) * 2023-04-25 2026-01-13 알페라바이오 엘엘씨 이미다졸 함유 화합물, 이의 유도체 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605661A (en) * 1984-06-18 1986-08-12 Eli Lilly And Company Aromastase inhibiting α,α-diarylimidazole-4(5)-propionitriles, α,α-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
US5439928A (en) * 1989-03-30 1995-08-08 Orion-Yhtyma Oy Aromatase inhibiting 4(5)-imidazoles
GB2248058B (en) * 1990-09-21 1994-09-14 Orion Yhtymae Oy Aromatase inhibiting 4(5)-imidazoles
AU627559B2 (en) * 1989-03-30 1992-08-27 Farmos-Yhtyma Oy Novel aromatase inhibiting 4(5)-imidazoles

Also Published As

Publication number Publication date
FI935658A7 (fi) 1993-12-16
SI9200113A (en) 1992-12-31
CN1068819A (zh) 1993-02-10
HRP920170A2 (en) 1994-08-31
IE921963A1 (en) 1992-12-30
PT100604A (pt) 1993-10-29
TW206217B (lt) 1993-05-21
AU665002B2 (en) 1995-12-14
AU1978392A (en) 1993-01-12
NO934688L (no) 1993-12-17
CZ280293A3 (en) 1994-05-18
NO934688D0 (no) 1993-12-17
IL102216A0 (en) 1993-01-14
LT3164B (en) 1995-02-27
CA2111469A1 (en) 1992-12-23
LV10093B (en) 1995-02-20
KR940701386A (ko) 1994-05-28
NZ243139A (en) 1994-08-26
JPH06508119A (ja) 1994-09-14
HU9303653D0 (en) 1994-04-28
WO1992022537A1 (en) 1992-12-23
LV10093A (lv) 1994-05-10
FI935658A0 (fi) 1993-12-16
EP0589975A1 (en) 1994-04-06
US5559141A (en) 1996-09-24
LTIP175A (lt) 1994-08-25
IL102216A (en) 1996-06-18
SK144393A3 (en) 1994-11-09
GB9125924D0 (en) 1992-02-05
MX9203000A (es) 1993-02-01
IL115439A0 (en) 1995-12-31
HUT67325A (en) 1995-03-28

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