BG99791A - 5-member heteroaryloxazolidinons - Google Patents

5-member heteroaryloxazolidinons Download PDF

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Publication number
BG99791A
BG99791A BG99791A BG9979195A BG99791A BG 99791 A BG99791 A BG 99791A BG 99791 A BG99791 A BG 99791A BG 9979195 A BG9979195 A BG 9979195A BG 99791 A BG99791 A BG 99791A
Authority
BG
Bulgaria
Prior art keywords
carbon atoms
linear
different
formula
group
Prior art date
Application number
BG99791A
Other languages
Bulgarian (bg)
English (en)
Inventor
Bernd Riedl
Dieter Haebich
Andreas Stolle
Hanno Wild
Rainer Endermann
Klaus D Bremm
Hein-Peter Kroll
Harald Labischinski
Klaus Schaller
Hans-Otto Werling
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BG99791A publication Critical patent/BG99791A/bg

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG99791A 1994-07-20 1995-07-18 5-member heteroaryloxazolidinons BG99791A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425613A DE4425613A1 (de) 1994-07-20 1994-07-20 5-gliedrige Heteroaryl-oxazolidinone

Publications (1)

Publication Number Publication Date
BG99791A true BG99791A (en) 1996-04-30

Family

ID=6523633

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99791A BG99791A (en) 1994-07-20 1995-07-18 5-member heteroaryloxazolidinons

Country Status (28)

Country Link
US (1) US5698574A (fr)
EP (1) EP0693491A1 (fr)
JP (1) JPH0853443A (fr)
KR (1) KR960004343A (fr)
CN (1) CN1121919A (fr)
AU (1) AU695661B2 (fr)
BG (1) BG99791A (fr)
CA (1) CA2154026A1 (fr)
CO (1) CO4410193A1 (fr)
CZ (1) CZ187395A3 (fr)
DE (1) DE4425613A1 (fr)
EE (1) EE9500044A (fr)
FI (1) FI953476L (fr)
HR (1) HRP950391A2 (fr)
HU (1) HUT74003A (fr)
IL (1) IL114622A (fr)
MA (1) MA23621A1 (fr)
NO (1) NO304488B1 (fr)
NZ (1) NZ272596A (fr)
PE (1) PE35896A1 (fr)
PL (1) PL309685A1 (fr)
RO (1) RO115161B1 (fr)
RU (1) RU95113086A (fr)
SK (1) SK91695A3 (fr)
SV (1) SV1995000042A (fr)
TN (1) TNSN95083A1 (fr)
YU (1) YU49195A (fr)
ZA (1) ZA956015B (fr)

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CA2208603A1 (fr) * 1995-02-03 1996-08-08 The Upjohn Company Phenyloxazolidinone substituee par un noyau heteroaromatique comme agent antimicrobien
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DE19601264A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
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AU3973697A (en) * 1996-08-21 1998-03-06 Pharmacia & Upjohn Company Isoxazoline derivatives useful as antimicrobials
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6262044B1 (en) * 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
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US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
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US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
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US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
CN1311787A (zh) 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
MY122454A (en) * 1998-06-05 2006-04-29 Upjohn Co Use of oxazolidinones for the preparation of a medicament for transdermal delivery
CA2334811A1 (fr) * 1998-07-14 2000-01-27 Pharmacia & Upjohn Company Oxazolidinones pour le traitement d'infections oculaires
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
AR020660A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Composiciones antibioticas para el tratamiento de ojos, oidos y nariz
AU4224699A (en) 1999-01-27 2000-08-18 Pharmacia & Upjohn Company Assays for modulators of elongation factor p activity
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
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US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
WO2002002095A2 (fr) 2000-06-30 2002-01-10 Pharmacia & Upjohn Company Composition et techniques de traitement d'infections bacteriennes
PE20020300A1 (es) * 2000-08-22 2002-05-10 Pharmacia Corp Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
WO2002018354A1 (fr) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones et leur utilisation en tant qu'agents antibacteriens
AR031135A1 (es) 2000-10-10 2003-09-10 Upjohn Co Composiciones de antibiotico topico para el tratamiento de infecciones oculares
ATE319710T1 (de) 2000-12-21 2006-03-15 Pharmacia & Upjohn Co Llc Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
GB0118407D0 (en) * 2001-07-27 2001-09-19 Cipla Ltd Oxazolidinone derivatives as antibacterial agents
JP2003192773A (ja) * 2001-12-26 2003-07-09 Mitsui Chemicals Inc 生体吸収性ポリヒドロキシカルボン酸及びその製造法
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
MXPA04008173A (es) * 2002-02-22 2004-11-26 Pharmacia Corp Formulaciones de farmaco antibiotico oftalmico que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio.
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
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DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
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Also Published As

Publication number Publication date
TNSN95083A1 (fr) 1996-02-06
IL114622A (en) 1999-07-14
CO4410193A1 (es) 1997-01-09
IL114622A0 (en) 1995-11-27
DE4425613A1 (de) 1996-01-25
ZA956015B (en) 1996-02-22
NO952866D0 (no) 1995-07-19
JPH0853443A (ja) 1996-02-27
CA2154026A1 (fr) 1996-01-21
RO115161B1 (ro) 1999-11-30
KR960004343A (ko) 1996-02-23
EE9500044A (et) 1996-02-15
AU2498895A (en) 1996-02-01
FI953476A0 (fi) 1995-07-18
AU695661B2 (en) 1998-08-20
CN1121919A (zh) 1996-05-08
HUT74003A (en) 1996-10-28
SV1995000042A (es) 1996-03-28
US5698574A (en) 1997-12-16
PL309685A1 (en) 1996-01-22
HRP950391A2 (en) 1997-06-30
NO304488B1 (no) 1998-12-28
PE35896A1 (es) 1996-10-14
RU95113086A (ru) 1997-06-27
YU49195A (sh) 1998-12-23
NO952866L (no) 1996-01-22
HU9502167D0 (en) 1995-09-28
EP0693491A1 (fr) 1996-01-24
FI953476A7 (fi) 1996-01-21
MA23621A1 (fr) 1996-04-01
FI953476L (fi) 1996-01-21
SK91695A3 (en) 1996-02-07
NZ272596A (en) 1997-03-24
CZ187395A3 (en) 1996-02-14

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