BR0010496A - Regulação da expressão genica viral - Google Patents
Regulação da expressão genica viralInfo
- Publication number
- BR0010496A BR0010496A BR0010496-5A BR0010496A BR0010496A BR 0010496 A BR0010496 A BR 0010496A BR 0010496 A BR0010496 A BR 0010496A BR 0010496 A BR0010496 A BR 0010496A
- Authority
- BR
- Brazil
- Prior art keywords
- viral gene
- regulation
- gene expression
- expression
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Patente de Invenção: "REGULAçãO DA EXPRESSãO GêNICA VIRAL". A presente invenção refere-se a processos para alterar a expressão de um gene viral em uma célula utilizando fragmentos de RNA sentido e antisenso do gene. Os fragmentos de RNA sentido e anti-sentido são capazes de formar pares e formar moléculas de RNA de filamento duplo, alterando desta forma a expressão do gene. A presente invenção refere-se também a células, plantas ou a animais, a sua progênie e a sementes derivadas das mesmas, obtidas utilizando um processo da presente invenção. Preferencialmente, tais células, plantas ou animais são resistentes ou tolerantes a vírus.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/309,038 US7019195B1 (en) | 1998-05-26 | 1999-05-10 | Method for conferring resistance or tolerance aganist furovirus, potyvirus, tospovirus, and cucomovirus to plant cells |
| PCT/EP2000/004117 WO2000068374A1 (en) | 1999-05-10 | 2000-05-08 | Regulation of viral gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0010496A true BR0010496A (pt) | 2002-04-02 |
Family
ID=23196412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0010496-5A BR0010496A (pt) | 1999-05-10 | 2000-05-08 | Regulação da expressão genica viral |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP1177283A1 (pt) |
| JP (3) | JP2002543783A (pt) |
| KR (1) | KR20010112952A (pt) |
| CN (2) | CN101348785A (pt) |
| AR (1) | AR023885A1 (pt) |
| AU (1) | AU4563300A (pt) |
| BR (1) | BR0010496A (pt) |
| CA (1) | CA2369422A1 (pt) |
| CZ (1) | CZ20014028A3 (pt) |
| EA (1) | EA200101186A1 (pt) |
| HK (2) | HK1047769B (pt) |
| HU (1) | HUP0201235A3 (pt) |
| IL (2) | IL145538A0 (pt) |
| PL (1) | PL351385A1 (pt) |
| SK (1) | SK16222001A3 (pt) |
| TR (1) | TR200103088T2 (pt) |
| WO (1) | WO2000068374A1 (pt) |
| ZA (1) | ZA200109152B (pt) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| US7067722B2 (en) | 1999-08-26 | 2006-06-27 | Monsanto Technology Llc | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
| ATE383433T1 (de) | 1999-08-26 | 2008-01-15 | Calgene Llc | Pflanzen mit veränderten mehrfachungesättigten fettsäuren |
| US7531718B2 (en) | 1999-08-26 | 2009-05-12 | Monsanto Technology, L.L.C. | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
| DE10100586C1 (de) | 2001-01-09 | 2002-04-11 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines Ziegens |
| CH695778A5 (de) * | 2000-11-29 | 2006-08-31 | Hoffmann La Roche | Hemmung der Transkription eines Zielgens in einer Zelle oder in Geweben. |
| US7767802B2 (en) | 2001-01-09 | 2010-08-03 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
| US7423142B2 (en) | 2001-01-09 | 2008-09-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
| US8022272B2 (en) | 2001-07-13 | 2011-09-20 | Sungene Gmbh & Co. Kgaa | Expression cassettes for transgenic expression of nucleic acids |
| US7456335B2 (en) | 2001-09-03 | 2008-11-25 | Basf Plant Science Gmbh | Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants |
| DE10163098B4 (de) | 2001-10-12 | 2005-06-02 | Alnylam Europe Ag | Verfahren zur Hemmung der Replikation von Viren |
| US7745418B2 (en) | 2001-10-12 | 2010-06-29 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting viral replication |
| DE10202419A1 (de) | 2002-01-22 | 2003-08-07 | Ribopharma Ag | Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens |
| US7601888B2 (en) | 2002-03-21 | 2009-10-13 | Monsanto Technology L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
| US7166771B2 (en) | 2002-06-21 | 2007-01-23 | Monsanto Technology Llc | Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs |
| US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
| WO2004013333A2 (de) | 2002-07-26 | 2004-02-12 | Basf Plant Science Gmbh | Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren |
| EP1529112A2 (en) | 2002-08-07 | 2005-05-11 | BASF Plant Science GmbH | Nucleic acid sequences encoding proteins associated with abiotic stress response |
| AU2004262656A1 (en) | 2003-08-01 | 2005-02-17 | Basf Plant Science Gmbh | Process for the production of fine chemicals in plants |
| EP2080769A3 (en) | 2004-07-02 | 2010-12-01 | Metanomics GmbH | Process for the production of fine chemicals |
| WO2006013072A2 (en) | 2004-08-02 | 2006-02-09 | Basf Plant Science Gmbh | Method for isolation of transcription termination sequences |
| EP1794304B1 (en) | 2004-09-24 | 2013-06-19 | BASF Plant Science GmbH | Plant cells and plants with increased tolerance to environmental stress |
| EP2163632A1 (en) | 2004-10-05 | 2010-03-17 | SunGene GmbH | Constitutive expression cassettes for regulation of plant expression |
| NZ582988A (en) * | 2004-10-21 | 2011-07-29 | Venganza Inc | Methods and materials for conferring resistance to pests and pathogens of plants |
| EP1655364A3 (en) | 2004-11-05 | 2006-08-02 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
| EP2163631B1 (en) | 2004-11-25 | 2013-05-22 | SunGene GmbH | Expression cassettes for guard cell-preferential expression in plants |
| EP1666599A3 (en) | 2004-12-04 | 2006-07-12 | SunGene GmbH | Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants |
| EP1669455B1 (en) | 2004-12-08 | 2009-10-28 | SunGene GmbH | Expression cassettes for vascular tissue-preferential expression in plants |
| EP1669456A3 (en) | 2004-12-11 | 2006-07-12 | SunGene GmbH | Expression cassettes for meristem-preferential expression in plants |
| CA2585798A1 (en) | 2004-12-17 | 2006-06-17 | Metanomics Gmbh | Process for the control of production of fine chemicals |
| CN101155922A (zh) | 2005-02-09 | 2008-04-02 | 巴斯福植物科学有限公司 | 在单子叶植物中调控表达的表达盒 |
| BRPI0607378A2 (pt) | 2005-02-26 | 2010-03-23 | Basf Plant Science Gmbh | cassetes de expressço, seqÜÊncia nucleotÍdica isolada, vetor, cÉlula hospedeira transgÊnica ou organismo nço humano, cÉlula de planta ou planta transgÊnica, mÉtodos para identificar e/ou isolar uma seqÜÊncia nucleotÍdica reguladora da transcriÇço, para prover ou produzir um cassete de expressço transgÊnica, e para prover uma seqÜÊncia nucleotÍdica reguladora de transcriÇço sintÉtica, e, seqÜÊncia reguladora de transcriÇço sintÉtica |
| EP2166100B1 (en) | 2005-03-08 | 2012-07-18 | BASF Plant Science GmbH | Expression enhancing intron sequences |
| EP1882037A2 (en) | 2005-05-10 | 2008-01-30 | BASF Plant Science GmbH | Expression cassettes for seed-preferential expression in plants |
| WO2006128572A1 (en) * | 2005-06-02 | 2006-12-07 | Syngenta Participations Ag | Ce46-02a insecticidal cotton |
| AU2006260924B2 (en) | 2005-06-23 | 2011-03-03 | Basf Plant Science Gmbh | Improved methods for the production of stably transformed, fertile zea mays plants |
| WO2007039454A1 (en) | 2005-09-20 | 2007-04-12 | Basf Plant Science Gmbh | Methods for controlling gene expression using ta-siran |
| EP1948806A2 (de) | 2005-11-08 | 2008-07-30 | BASF Plant Science GmbH | Verwendung von armadillo-repeat (arm1)-polynukleotiden zum erreichen einer pathogenresistenz in pflanzen |
| US8178751B2 (en) | 2006-01-12 | 2012-05-15 | Basf Plant Science Gmbh | Use of stomatin (STM1) polynucleotides for achieving a pathogen resistance in plants |
| CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
| CA2644273A1 (en) | 2006-04-05 | 2008-03-27 | Metanomics Gmbh | Process for the production of a fine chemical |
| KR100809736B1 (ko) | 2006-05-15 | 2008-03-05 | 대한민국 | 안토시아닌 생합성 억제 활성을 가진 myb60 유전자와상기 유전자가 도입된 형질전환 상추 및 그 제조방법 |
| WO2008074025A2 (en) * | 2006-12-13 | 2008-06-19 | Idiverse, Inc. | Novel genes and rna molecules that confer stress tolerance |
| US8592652B2 (en) | 2007-01-15 | 2013-11-26 | Basf Plant Science Gmbh | Use of subtilisin-like RNR9 polynucleotide for achieving pathogen resistance in plants |
| EP2074219B1 (en) | 2007-02-16 | 2013-11-20 | BASF Plant Science GmbH | Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants |
| EP2074220A2 (en) | 2007-05-22 | 2009-07-01 | BASF Plant Science GmbH | Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-ko |
| BRPI0821009A2 (pt) | 2007-12-21 | 2019-09-24 | Basf Plant Science Gmbh | métodos para aumentar o rendimento de uma planta e para produzir uma célula de planta transgênica, uma planta ou uma parte e para determinar o teor de nitrogênio de solo de teste, moléculas, moléculas de ácido nucléico isolada e de ácido nucleico viral, oligoiniciador, mutante negativo dominante de polipeptideo, construto de ácido nucleico, vetor, célula de planta transgênica, planta ou uma parte da mesma, polipeptideo, anticorpo, tecido de planta, planta, material de planta colhida ou material de propagação de uma planta, processo para produzir um polipeptideo, composição de alimento ou ração, e, uso |
| CN107699545A (zh) | 2008-09-29 | 2018-02-16 | 孟山都技术公司 | 大豆转基因时间mon87705及其检测方法 |
| EP2208785A1 (en) * | 2009-01-15 | 2010-07-21 | Newbiotechnic, S.A. | Methods and kits to generate miRNA- and smallRNA-expressing vectors, and its application to develop lentiviral expression libraries |
| EP2421976B1 (en) | 2009-04-22 | 2015-09-16 | BASF Plant Science Company GmbH | Whole seed specific promoter |
| BR112012000448A2 (pt) | 2009-07-10 | 2015-10-06 | Basf Plant Science Gmbh | cassete de expressão para a regulação da expressão semente-específica de um polinucleotídeo de interesse, vetor, célula hospedeira, tecido de planta, órgão de planta, planta ou semente transgênicos, metodo para expressar um polinucleotídeo de interesse em uma célula hospedeira, métodos para produzir um tecido vegetal, órgão de planta, planta, ou semente transgênicos e uso do cassete de expressão |
| WO2011067712A1 (en) | 2009-12-03 | 2011-06-09 | Basf Plant Science Company Gmbh | Expression cassettes for embryo-specific expression in plants |
| KR101457958B1 (ko) * | 2010-07-14 | 2014-11-04 | 대한민국 | 다종 바이러스 저항성을 갖는 형질전환 감자 식물체의 제조방법 및 이를 이용하여 제조된 감자 식물체 |
| CN103667322B (zh) * | 2013-11-21 | 2015-11-11 | 上海市农业科学院 | 一种抗番茄黄化曲叶病毒的多基因嵌合体avctc及其制备方法和应用 |
| JP2017512070A (ja) * | 2014-03-12 | 2017-05-18 | ザ ユニバーシティ オブ シドニー | 高等植物におけるrnaの生成 |
| CN111465323A (zh) * | 2017-05-22 | 2020-07-28 | 美国卵石实验室公司 | 细菌基因表达的跨生物调节 |
| CN116004714B (zh) * | 2022-07-27 | 2024-09-10 | 武汉大学 | 基于Spacer基因定向插入TC-Tag标签的细胞系、重组病毒及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0473576A4 (en) * | 1989-05-19 | 1993-03-10 | Hem Research, Inc. | Short therapeutic dsrna of defined structure |
| DK0517833T4 (da) * | 1990-03-02 | 2008-11-17 | Bayer Bioscience Nv | Genetisk transformation og regenering af sukkerroer |
| GB9320548D0 (en) * | 1993-10-06 | 1993-11-24 | Sandoz Ltd | Improvements in or relating to organic compounds |
| GB9703146D0 (en) * | 1997-02-14 | 1997-04-02 | Innes John Centre Innov Ltd | Methods and means for gene silencing in transgenic plants |
| CA2281002A1 (en) * | 1997-02-19 | 1998-08-27 | Cornell Research Foundation, Inc. | Dna construct to confer multiple traits on plants |
| GB9710475D0 (en) * | 1997-05-21 | 1997-07-16 | Zeneca Ltd | Gene silencing |
| GB9720148D0 (en) * | 1997-09-22 | 1997-11-26 | Innes John Centre Innov Ltd | Gene silencing materials and methods |
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| CN101818145A (zh) * | 1998-03-20 | 2010-09-01 | 联邦科学和工业研究组织 | 控制基因表达 |
| CN1202246C (zh) * | 1998-04-08 | 2005-05-18 | 联邦科学和工业研究组织 | 获得修饰表型的方法和措施 |
| AR020078A1 (es) * | 1998-05-26 | 2002-04-10 | Syngenta Participations Ag | Metodo para alterar la expresion de un gen objetivo en una celula de planta |
| CA2361201A1 (en) * | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
-
2000
- 2000-05-08 KR KR1020017014335A patent/KR20010112952A/ko not_active Withdrawn
- 2000-05-08 JP JP2000616341A patent/JP2002543783A/ja not_active Withdrawn
- 2000-05-08 AU AU45633/00A patent/AU4563300A/en not_active Abandoned
- 2000-05-08 EA EA200101186A patent/EA200101186A1/ru unknown
- 2000-05-08 CA CA002369422A patent/CA2369422A1/en not_active Abandoned
- 2000-05-08 EP EP00927165A patent/EP1177283A1/en not_active Withdrawn
- 2000-05-08 CN CNA2008102106166A patent/CN101348785A/zh active Pending
- 2000-05-08 HU HU0201235A patent/HUP0201235A3/hu unknown
- 2000-05-08 CZ CZ20014028A patent/CZ20014028A3/cs unknown
- 2000-05-08 EP EP06026160A patent/EP1801215B1/en not_active Expired - Lifetime
- 2000-05-08 TR TR2001/03088T patent/TR200103088T2/xx unknown
- 2000-05-08 SK SK1622-2001A patent/SK16222001A3/sk unknown
- 2000-05-08 WO PCT/EP2000/004117 patent/WO2000068374A1/en not_active Ceased
- 2000-05-08 BR BR0010496-5A patent/BR0010496A/pt not_active Application Discontinuation
- 2000-05-08 CN CNB008073597A patent/CN100420748C/zh not_active Expired - Fee Related
- 2000-05-08 AR ARP000102213A patent/AR023885A1/es not_active Application Discontinuation
- 2000-05-08 HK HK02109393.2A patent/HK1047769B/zh not_active IP Right Cessation
- 2000-05-08 IL IL14553800A patent/IL145538A0/xx unknown
- 2000-05-08 HK HK02105312.8A patent/HK1045325A1/zh unknown
- 2000-05-08 PL PL00351385A patent/PL351385A1/xx not_active IP Right Cessation
-
2001
- 2001-09-21 IL IL145538A patent/IL145538A/en not_active IP Right Cessation
- 2001-11-06 ZA ZA200109152A patent/ZA200109152B/en unknown
-
2008
- 2008-09-02 JP JP2008224753A patent/JP2009022291A/ja not_active Withdrawn
-
2009
- 2009-11-06 JP JP2009255087A patent/JP2010088435A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2369422A1 (en) | 2000-11-16 |
| JP2010088435A (ja) | 2010-04-22 |
| WO2000068374A1 (en) | 2000-11-16 |
| AU4563300A (en) | 2000-11-21 |
| JP2009022291A (ja) | 2009-02-05 |
| HK1047769B (zh) | 2009-08-14 |
| ZA200109152B (en) | 2002-09-06 |
| EP1177283A1 (en) | 2002-02-06 |
| EA200101186A1 (ru) | 2002-04-25 |
| HK1047769A1 (en) | 2003-03-07 |
| JP2002543783A (ja) | 2002-12-24 |
| CN101348785A (zh) | 2009-01-21 |
| PL351385A1 (en) | 2003-04-07 |
| CN100420748C (zh) | 2008-09-24 |
| HUP0201235A2 (en) | 2002-08-28 |
| HK1045325A1 (zh) | 2002-11-22 |
| CN1357040A (zh) | 2002-07-03 |
| EP1801215B1 (en) | 2013-02-27 |
| HUP0201235A3 (en) | 2004-10-28 |
| CZ20014028A3 (cs) | 2002-02-13 |
| IL145538A (en) | 2010-11-30 |
| SK16222001A3 (sk) | 2002-04-04 |
| TR200103088T2 (tr) | 2002-05-21 |
| EP1801215A3 (en) | 2008-12-17 |
| KR20010112952A (ko) | 2001-12-22 |
| EP1801215A2 (en) | 2007-06-27 |
| IL145538A0 (en) | 2002-06-30 |
| AR023885A1 (es) | 2002-09-04 |
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