BR0012467A - Agente terapêutico para hipercalcemia resistente à droga - Google Patents

Agente terapêutico para hipercalcemia resistente à droga

Info

Publication number
BR0012467A
BR0012467A BR0012467-2A BR0012467A BR0012467A BR 0012467 A BR0012467 A BR 0012467A BR 0012467 A BR0012467 A BR 0012467A BR 0012467 A BR0012467 A BR 0012467A
Authority
BR
Brazil
Prior art keywords
therapeutic agent
drug
resistant hypercalcemia
hypercalcemia
resistant
Prior art date
Application number
BR0012467-2A
Other languages
English (en)
Inventor
Hidemi Saito
Toshiaki Tsunenari
Etsuro Onuma
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of BR0012467A publication Critical patent/BR0012467A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"AGENTE TERAPêUTICO PARA HIPERCALCEMIA RESISTENTE à DROGA". A presente invenção refere-se a um agente terapêutico para hipercalcemia resistente à droga. O agente terapêutico compreende, como um ingrediente ativo, uma substância capaz de inibir a ligação entre uma proteína relacionada com o hormónio da paratireóide ( PTHrP ) e um receptor deste.
BR0012467-2A 1999-07-06 2000-07-06 Agente terapêutico para hipercalcemia resistente à droga BR0012467A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19227099 1999-07-06
PCT/JP2000/004523 WO2001002012A1 (fr) 1999-07-06 2000-07-06 Remedes contre l'hypercalcemie chimio-resistante

Publications (1)

Publication Number Publication Date
BR0012467A true BR0012467A (pt) 2002-06-11

Family

ID=16288493

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012467-2A BR0012467A (pt) 1999-07-06 2000-07-06 Agente terapêutico para hipercalcemia resistente à droga

Country Status (17)

Country Link
EP (1) EP1195164A4 (pt)
KR (1) KR20020040743A (pt)
CN (1) CN1399557A (pt)
AR (1) AR020867A1 (pt)
AU (1) AU5849700A (pt)
BR (1) BR0012467A (pt)
CA (1) CA2373945A1 (pt)
CZ (1) CZ20014730A3 (pt)
HK (1) HK1046235A1 (pt)
HU (1) HUP0202218A3 (pt)
MX (1) MXPA02000018A (pt)
NO (1) NO20020044L (pt)
PL (1) PL353407A1 (pt)
RU (1) RU2002102916A (pt)
SK (1) SK162002A3 (pt)
WO (1) WO2001002012A1 (pt)
ZA (1) ZA200200264B (pt)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02207099A (ja) * 1989-02-07 1990-08-16 Tonen Corp PTHrP関連ペプチド、その製造法及び用途
CA2035179C (en) * 1990-01-31 2001-08-14 Gerald S. Brenner Pharmaceutical compositions containing insoluble salts of bisphosphonic acids
JPH04228089A (ja) * 1990-05-15 1992-08-18 Kanegafuchi Chem Ind Co Ltd 高カルシウム血症治療・予防剤
CA2087190A1 (en) * 1990-07-13 1992-01-14 Fred E. Cohen Parathyroid hormone analogues modified at positions
ATE287898T1 (de) * 1991-04-05 2005-02-15 Gen Hospital Corp Parathyroid-hormon-rezeptor und seine kodierende dna
US5849695A (en) * 1993-01-13 1998-12-15 The Regents Of The University Of California Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals
JP3504697B2 (ja) * 1993-09-30 2004-03-08 株式会社先端生命科学研究所 PTHrPアンタゴニスト活性を有するポリペプチド及びそれを含むカルシウム代謝治療薬
CO4410206A1 (es) * 1994-07-28 1997-01-09 Sandoz Ag DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
CA2219361C (en) * 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
SK40599A3 (en) * 1996-09-26 2000-06-12 Chugai Pharmaceutical Co Ltd Antibody against human parathormone related peptides
JP4372240B2 (ja) * 1997-05-15 2009-11-25 中外製薬株式会社 悪液質治療剤
PL345117A1 (en) * 1998-06-26 2001-12-03 Chugai Pharmaceutical Co Ltd Remedies for hypercalcemic crisis
TWI255718B (en) * 1999-07-02 2006-06-01 Chugai Pharmaceutical Co Ltd Ameliorative agent for low vasopressin concentration

Also Published As

Publication number Publication date
AU5849700A (en) 2001-01-22
CA2373945A1 (en) 2001-01-11
SK162002A3 (en) 2002-06-04
EP1195164A4 (en) 2005-09-28
CZ20014730A3 (cs) 2002-04-17
NO20020044D0 (no) 2002-01-04
HK1046235A1 (en) 2003-01-03
PL353407A1 (en) 2003-11-17
MXPA02000018A (es) 2003-07-21
EP1195164A1 (en) 2002-04-10
HUP0202218A2 (en) 2002-10-28
WO2001002012A1 (fr) 2001-01-11
WO2001002012A8 (fr) 2002-06-06
HUP0202218A3 (en) 2005-01-28
KR20020040743A (ko) 2002-05-30
CN1399557A (zh) 2003-02-26
ZA200200264B (en) 2003-04-30
NO20020044L (no) 2002-03-01
RU2002102916A (ru) 2003-11-10
AR020867A1 (es) 2002-05-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.