BR0012467A - Agente terapêutico para hipercalcemia resistente à droga - Google Patents
Agente terapêutico para hipercalcemia resistente à drogaInfo
- Publication number
- BR0012467A BR0012467A BR0012467-2A BR0012467A BR0012467A BR 0012467 A BR0012467 A BR 0012467A BR 0012467 A BR0012467 A BR 0012467A BR 0012467 A BR0012467 A BR 0012467A
- Authority
- BR
- Brazil
- Prior art keywords
- therapeutic agent
- drug
- resistant hypercalcemia
- hypercalcemia
- resistant
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 6
- 229940124597 therapeutic agent Drugs 0.000 title abstract 4
- 208000037147 Hypercalcaemia Diseases 0.000 title abstract 3
- 230000000148 hypercalcaemia Effects 0.000 title abstract 3
- 208000030915 hypercalcemia disease Diseases 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 2
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 abstract 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 102000043299 Parathyroid hormone-related Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000199 parathyroid hormone Substances 0.000 abstract 1
- 229960001319 parathyroid hormone Drugs 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"AGENTE TERAPêUTICO PARA HIPERCALCEMIA RESISTENTE à DROGA". A presente invenção refere-se a um agente terapêutico para hipercalcemia resistente à droga. O agente terapêutico compreende, como um ingrediente ativo, uma substância capaz de inibir a ligação entre uma proteína relacionada com o hormónio da paratireóide ( PTHrP ) e um receptor deste.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19227099 | 1999-07-06 | ||
| PCT/JP2000/004523 WO2001002012A1 (fr) | 1999-07-06 | 2000-07-06 | Remedes contre l'hypercalcemie chimio-resistante |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0012467A true BR0012467A (pt) | 2002-06-11 |
Family
ID=16288493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0012467-2A BR0012467A (pt) | 1999-07-06 | 2000-07-06 | Agente terapêutico para hipercalcemia resistente à droga |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1195164A4 (pt) |
| KR (1) | KR20020040743A (pt) |
| CN (1) | CN1399557A (pt) |
| AR (1) | AR020867A1 (pt) |
| AU (1) | AU5849700A (pt) |
| BR (1) | BR0012467A (pt) |
| CA (1) | CA2373945A1 (pt) |
| CZ (1) | CZ20014730A3 (pt) |
| HK (1) | HK1046235A1 (pt) |
| HU (1) | HUP0202218A3 (pt) |
| MX (1) | MXPA02000018A (pt) |
| NO (1) | NO20020044L (pt) |
| PL (1) | PL353407A1 (pt) |
| RU (1) | RU2002102916A (pt) |
| SK (1) | SK162002A3 (pt) |
| WO (1) | WO2001002012A1 (pt) |
| ZA (1) | ZA200200264B (pt) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02207099A (ja) * | 1989-02-07 | 1990-08-16 | Tonen Corp | PTHrP関連ペプチド、その製造法及び用途 |
| CA2035179C (en) * | 1990-01-31 | 2001-08-14 | Gerald S. Brenner | Pharmaceutical compositions containing insoluble salts of bisphosphonic acids |
| JPH04228089A (ja) * | 1990-05-15 | 1992-08-18 | Kanegafuchi Chem Ind Co Ltd | 高カルシウム血症治療・予防剤 |
| CA2087190A1 (en) * | 1990-07-13 | 1992-01-14 | Fred E. Cohen | Parathyroid hormone analogues modified at positions |
| ATE287898T1 (de) * | 1991-04-05 | 2005-02-15 | Gen Hospital Corp | Parathyroid-hormon-rezeptor und seine kodierende dna |
| US5849695A (en) * | 1993-01-13 | 1998-12-15 | The Regents Of The University Of California | Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals |
| JP3504697B2 (ja) * | 1993-09-30 | 2004-03-08 | 株式会社先端生命科学研究所 | PTHrPアンタゴニスト活性を有するポリペプチド及びそれを含むカルシウム代謝治療薬 |
| CO4410206A1 (es) * | 1994-07-28 | 1997-01-09 | Sandoz Ag | DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
| CA2219361C (en) * | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| SK40599A3 (en) * | 1996-09-26 | 2000-06-12 | Chugai Pharmaceutical Co Ltd | Antibody against human parathormone related peptides |
| JP4372240B2 (ja) * | 1997-05-15 | 2009-11-25 | 中外製薬株式会社 | 悪液質治療剤 |
| PL345117A1 (en) * | 1998-06-26 | 2001-12-03 | Chugai Pharmaceutical Co Ltd | Remedies for hypercalcemic crisis |
| TWI255718B (en) * | 1999-07-02 | 2006-06-01 | Chugai Pharmaceutical Co Ltd | Ameliorative agent for low vasopressin concentration |
-
2000
- 2000-07-06 SK SK16-2002A patent/SK162002A3/sk unknown
- 2000-07-06 AR ARP000103428A patent/AR020867A1/es unknown
- 2000-07-06 RU RU2002102916/15A patent/RU2002102916A/ru not_active Application Discontinuation
- 2000-07-06 AU AU58497/00A patent/AU5849700A/en not_active Abandoned
- 2000-07-06 WO PCT/JP2000/004523 patent/WO2001002012A1/ja not_active Ceased
- 2000-07-06 MX MXPA02000018A patent/MXPA02000018A/es unknown
- 2000-07-06 HU HU0202218A patent/HUP0202218A3/hu unknown
- 2000-07-06 CA CA002373945A patent/CA2373945A1/en not_active Abandoned
- 2000-07-06 CN CN00810001A patent/CN1399557A/zh active Pending
- 2000-07-06 CZ CZ20014730A patent/CZ20014730A3/cs unknown
- 2000-07-06 BR BR0012467-2A patent/BR0012467A/pt not_active IP Right Cessation
- 2000-07-06 PL PL00353407A patent/PL353407A1/xx not_active Application Discontinuation
- 2000-07-06 EP EP00944313A patent/EP1195164A4/en not_active Withdrawn
- 2000-07-06 KR KR1020027000220A patent/KR20020040743A/ko not_active Ceased
- 2000-07-06 HK HK02106436.7A patent/HK1046235A1/en unknown
-
2002
- 2002-01-04 NO NO20020044A patent/NO20020044L/no unknown
- 2002-01-11 ZA ZA200200264A patent/ZA200200264B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5849700A (en) | 2001-01-22 |
| CA2373945A1 (en) | 2001-01-11 |
| SK162002A3 (en) | 2002-06-04 |
| EP1195164A4 (en) | 2005-09-28 |
| CZ20014730A3 (cs) | 2002-04-17 |
| NO20020044D0 (no) | 2002-01-04 |
| HK1046235A1 (en) | 2003-01-03 |
| PL353407A1 (en) | 2003-11-17 |
| MXPA02000018A (es) | 2003-07-21 |
| EP1195164A1 (en) | 2002-04-10 |
| HUP0202218A2 (en) | 2002-10-28 |
| WO2001002012A1 (fr) | 2001-01-11 |
| WO2001002012A8 (fr) | 2002-06-06 |
| HUP0202218A3 (en) | 2005-01-28 |
| KR20020040743A (ko) | 2002-05-30 |
| CN1399557A (zh) | 2003-02-26 |
| ZA200200264B (en) | 2003-04-30 |
| NO20020044L (no) | 2002-03-01 |
| RU2002102916A (ru) | 2003-11-10 |
| AR020867A1 (es) | 2002-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |