BR0013562A - Processo para a fabricação de grãos contendo uma substância ativa, grãos porosos de rápida desintegração e utilização dos grãos - Google Patents

Processo para a fabricação de grãos contendo uma substância ativa, grãos porosos de rápida desintegração e utilização dos grãos

Info

Publication number
BR0013562A
BR0013562A BR0013562-3A BR0013562A BR0013562A BR 0013562 A BR0013562 A BR 0013562A BR 0013562 A BR0013562 A BR 0013562A BR 0013562 A BR0013562 A BR 0013562A
Authority
BR
Brazil
Prior art keywords
grains
manufacture
porous
active substance
quintosano
Prior art date
Application number
BR0013562-3A
Other languages
English (en)
Inventor
Hans Rainer Hoffmann
Bodo Asmussen
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BR0013562A publication Critical patent/BR0013562A/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"PROCESSO PARA A FABRICAçãO DE GRãOS CONTENDO UMA SUBSTâNCIA ATIVA, GRãOS POROSOS DE RáPIDA DESINTEGRAçãO E UTILIZAçãO DOS GRãOS". A presente invenção se refere a grãos contendo uma substância ativa à base de quintosano ou num derivado básico de quintosano, os quais são porosos de fácil desintegração, fabricados de acordo com um método de gotejamento, no qual uma solução aquosa ou de dispersão de quintosano ou um derivado básico de quintosano, uma ou mais substâncias ativas, possivelmente substâncias ativas adicionais e um ácido, são gotejados num líquido de resfriamento tendo uma temperatura de no máximo -5<198>C, portanto causando a solidificação da solução ou da substância de dispersão na forma de gotículas, e onde as gotículas ou grãos são isolados e secos. A invenção adicionalmente se relaciona a utilização destes grãos na fabricação de medicamentos ou e agentes de diagnósticos.
BR0013562-3A 1999-08-27 2000-08-14 Processo para a fabricação de grãos contendo uma substância ativa, grãos porosos de rápida desintegração e utilização dos grãos BR0013562A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19940795A DE19940795A1 (de) 1999-08-27 1999-08-27 Schnellzerfallende Pellets auf der Basis von Chitosan
PCT/EP2000/007897 WO2001016218A1 (de) 1999-08-27 2000-08-14 Schnellzerfallende pellets auf der basis von chitosan

Publications (1)

Publication Number Publication Date
BR0013562A true BR0013562A (pt) 2002-07-16

Family

ID=7919872

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013562-3A BR0013562A (pt) 1999-08-27 2000-08-14 Processo para a fabricação de grãos contendo uma substância ativa, grãos porosos de rápida desintegração e utilização dos grãos

Country Status (26)

Country Link
US (1) US6770300B1 (pt)
EP (1) EP1208140B1 (pt)
JP (1) JP4944327B2 (pt)
KR (1) KR100610176B1 (pt)
CN (1) CN1208381C (pt)
AR (1) AR025393A1 (pt)
AT (1) ATE331755T1 (pt)
AU (1) AU768328B2 (pt)
BR (1) BR0013562A (pt)
CA (1) CA2382902C (pt)
CZ (1) CZ300123B6 (pt)
DE (2) DE19940795A1 (pt)
DK (1) DK1208140T3 (pt)
ES (1) ES2267562T3 (pt)
HK (1) HK1047122A1 (pt)
HU (1) HUP0203079A3 (pt)
IL (1) IL148221A (pt)
MX (1) MXPA02002047A (pt)
NZ (1) NZ517542A (pt)
PL (1) PL203820B1 (pt)
PT (1) PT1208140E (pt)
RU (1) RU2248790C2 (pt)
TR (1) TR200200519T2 (pt)
TW (1) TW477697B (pt)
WO (1) WO2001016218A1 (pt)
ZA (1) ZA200201136B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE387487T1 (de) * 2003-05-23 2008-03-15 Procter & Gamble Waschmittelzusammensetzung zum gebrauch in einer textilwasch- oder geschirrspülmaschine
EP1627573A1 (en) * 2004-08-20 2006-02-22 Firmenich Sa A process for the incorporation of a flavor or fragrance ingredient or composition into a carbohydrate matrix
EP1993637A2 (en) * 2006-02-15 2008-11-26 Medingo Ltd. Systems and methods for sensing analyte and dispensing therapeutic fluid
WO2009153634A1 (en) 2008-06-19 2009-12-23 University Of Witwatersrand, Johannesburg A transmucosal delivery system
MX2012005090A (es) * 2009-11-02 2012-06-19 Mannkind Corp Aparato y metodo para la criogranulacion de una composicion farmaceutica.
JP6392907B2 (ja) * 2016-04-14 2018-09-19 株式会社新菱 ガス含有基材およびその製造方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57104628A (en) * 1980-12-23 1982-06-29 Nippon Steel Corp Production of high-strength stainless steel plate
DE3264450D1 (en) * 1981-12-11 1985-08-01 Wyeth John & Brother Ltd Process and apparatus for freezing a liquid medium
JPS6036410A (ja) * 1983-08-08 1985-02-25 Unitika Ltd 生分解性薬物供与体の製造方法
JPS6140337A (ja) * 1984-07-31 1986-02-26 Fuji Boseki Kk 粒状多孔質キトサンの製造方法
JPS62167331A (ja) * 1986-01-20 1987-07-23 Unitika Ltd キトサンスポンジ
DE3711169A1 (de) 1987-04-02 1988-10-20 Messer Griesheim Gmbh Vorrichtung zum kontrollierten einfrieren von zaehfliessenden fluessigkeiten
JPH01152104A (ja) 1987-12-08 1989-06-14 Hokkaido Soda Kk 水溶性キトサン塩粉末の製造方法
JPH02261838A (ja) * 1989-04-03 1990-10-24 Sumitomo Cement Co Ltd 多孔質キトサン材料の製造方法
DK0454044T3 (da) * 1990-04-25 1996-04-22 Hoechst Ag Farmakologisk præparat indeholdende polyelektrolytkomplekser på mikropartikelform og mindst et virksomt stof
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
JPH04185601A (ja) * 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
ATE172637T1 (de) * 1991-12-24 1998-11-15 Yamanouchi Pharma Co Ltd Intrabukkal desintegrierende zubereitung und ihre herstellung
DE4201179A1 (de) * 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
DE4201173C2 (de) 1992-01-17 1998-10-29 Alfatec Pharma Gmbh Akutarzneimittel in Form von Dihydropyridinderivaten enthaltenden Pellets und ihre Herstellung
DE4201172C1 (en) 1992-01-17 1993-07-22 Alfatec-Pharma Gmbh, 6900 Heidelberg, De Pellets contg. Aloe vera extract - useful, e.g. as antiinflammatory of antibiotic agents, or for treating gastric ulcers
GB2311027B (en) * 1996-03-15 1999-10-27 Johnson & Johnson Medical Coated bioabsorbable beads for wound treatment
GB2330532A (en) * 1996-07-10 1999-04-28 Danbiosyst Uk Compositions suitable for delivery of genes to epithelial cells
AU3461597A (en) * 1996-07-19 1998-02-10 Yamanouchi Pharmaceutical Co., Ltd. Water-insoluble porous particles of biocompatible substances and process for producing the same
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
DE19756314C2 (de) * 1997-12-12 2000-06-29 Roland Bodmeier Zubereitung mit verlängerter Verweildauer am Applikationsort
DE19845246A1 (de) * 1997-12-18 1999-06-24 Henkel Kgaa Vitaminhaltige Zubereitungen

Also Published As

Publication number Publication date
EP1208140B1 (de) 2006-06-28
EP1208140A1 (de) 2002-05-29
AU768328B2 (en) 2003-12-11
CZ300123B6 (cs) 2009-02-18
HUP0203079A3 (en) 2004-05-28
AU7275500A (en) 2001-03-26
AR025393A1 (es) 2002-11-27
CA2382902A1 (en) 2001-03-08
JP4944327B2 (ja) 2012-05-30
DE19940795A1 (de) 2001-03-01
CZ2002654A3 (cs) 2002-07-17
CN1208381C (zh) 2005-06-29
RU2248790C2 (ru) 2005-03-27
DK1208140T3 (da) 2006-10-30
MXPA02002047A (es) 2002-08-20
TR200200519T2 (tr) 2002-06-21
CA2382902C (en) 2009-02-03
PL353890A1 (en) 2003-12-15
KR100610176B1 (ko) 2006-08-09
DE50013092D1 (de) 2006-08-10
ES2267562T3 (es) 2007-03-16
IL148221A (en) 2005-12-18
US6770300B1 (en) 2004-08-03
IL148221A0 (en) 2002-09-12
PT1208140E (pt) 2006-11-30
CN1370195A (zh) 2002-09-18
PL203820B1 (pl) 2009-11-30
HK1047122A1 (zh) 2003-02-07
TW477697B (en) 2002-03-01
WO2001016218A1 (de) 2001-03-08
ATE331755T1 (de) 2006-07-15
JP2003508565A (ja) 2003-03-04
NZ517542A (en) 2003-06-30
ZA200201136B (en) 2002-08-28
HUP0203079A2 (hu) 2003-01-28
KR20020033774A (ko) 2002-05-07

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]

Free format text: DE ACORDO COM ART. 34 (II) DA LEI NO 9.279, DE 14 DE MAIO DE 1996.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2256 DE 01/04/2014.