BR0014945A - Modificação pós-traducional de proteìnas recombinantes produzidas em plantas - Google Patents

Modificação pós-traducional de proteìnas recombinantes produzidas em plantas

Info

Publication number
BR0014945A
BR0014945A BR0014945-4A BR0014945A BR0014945A BR 0014945 A BR0014945 A BR 0014945A BR 0014945 A BR0014945 A BR 0014945A BR 0014945 A BR0014945 A BR 0014945A
Authority
BR
Brazil
Prior art keywords
plants
genetically engineered
recombinant proteins
proteins produced
posttranslational modification
Prior art date
Application number
BR0014945-4A
Other languages
English (en)
Inventor
Douglas Russell
Siva Manjunath
Ronald Bassuner
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR0014945A publication Critical patent/BR0014945A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"MODIFICAçãO PóS-TRADUCIONAL DE PROTEINAS RECOMBINANTES PRODUZIDAS EM PLANTAS". A presente invenção se refere a um processo para a produção de proteínas ou polipeptídeos usando-se plantas ou células de plantas geneticamente manipuladas, bem como a plantas ou células de plantas geneticamente manipuladas per se (incluindo partes de plantas geneticamente manipuladas), o material proteico heterólogo (por exemplo, uma proteína, polipeptídeo e semelhantes), o qual é produzido com o auxílio dessas plantas ou células de plantas geneticamente manipuladas, e a polinucleotídeos recombinantes (DNA ou RNA) que são usados para a manipulação genética.
BR0014945-4A 1999-10-21 2000-10-20 Modificação pós-traducional de proteìnas recombinantes produzidas em plantas BR0014945A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16075899P 1999-10-21 1999-10-21
US19528200P 2000-04-07 2000-04-07
PCT/US2000/029027 WO2001029242A2 (en) 1999-10-21 2000-10-20 Post-translational modification of recombinant proteins produced in plants

Publications (1)

Publication Number Publication Date
BR0014945A true BR0014945A (pt) 2004-08-31

Family

ID=26857200

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014945-4A BR0014945A (pt) 1999-10-21 2000-10-20 Modificação pós-traducional de proteìnas recombinantes produzidas em plantas

Country Status (5)

Country Link
EP (1) EP1224309A2 (pt)
AU (1) AU1573601A (pt)
BR (1) BR0014945A (pt)
CA (1) CA2388432A1 (pt)
WO (1) WO2001029242A2 (pt)

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US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US7632983B2 (en) 2000-07-31 2009-12-15 Biolex Therapeutics, Inc. Expression of monoclonal antibodies in duckweed
MXPA03006426A (es) 2001-01-19 2003-09-22 Dow Chemical Co Metodo para produccion secretoria de glicoproteina que tiene cadena de azucar humana, utilizando celula de planta.
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US20030084482A1 (en) * 2001-06-08 2003-05-01 Gerald Hall Production of proteins in plants
EP1997829A1 (en) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin fusion proteins
EP2339004B1 (en) * 2002-03-19 2015-02-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
JP5350573B2 (ja) 2002-03-19 2013-11-27 スティヒティング ディーンスト ランドバウクンディフ オンデルズーク 植物におけるｇｎｔｉｉｉ発現
AU2008202355B2 (en) * 2002-03-19 2011-04-07 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
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WO2004057002A2 (en) * 2002-12-20 2004-07-08 Greenovation Biotech Gmbh Production of heterologous glycosylated proteins in bryophyte cells
DE60213626T2 (de) * 2002-12-20 2007-08-09 Greenovation Biotech Gmbh Verfahren zur Herstellung von glykosylierten Proteinen in Bryophyten Zellen
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CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
ATE475708T1 (de) * 2003-01-22 2010-08-15 Glycart Biotechnology Ag Fusionskonstrukte und deren verwendung zur produktion von antikörpern mit erhöhter fc rezeptor bindungsaffinität und effektorfunktion
CN100427599C (zh) * 2003-12-26 2008-10-22 吉林大学第一医院 Albsin/il－18mat杂交细胞因子
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
ATE479762T1 (de) * 2004-09-29 2010-09-15 Collplant Ltd Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung
EP1973940A2 (en) 2006-01-17 2008-10-01 Biolex Therapeutics, Inc. Compositions and methods for humanization and optimization of n-glycans in plants
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BRPI0812538B1 (pt) * 2007-06-15 2021-03-16 Medicago Inc. processo para a síntese de uma proteína de interesse com fucosilação e xilosilação reduzidas, ácido nucleico, e proteína híbrida gnt1-galt
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Also Published As

Publication number Publication date
WO2001029242A3 (en) 2002-02-21
CA2388432A1 (en) 2001-04-26
AU1573601A (en) 2001-04-30
EP1224309A2 (en) 2002-07-24
WO2001029242A2 (en) 2001-04-26

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]