BR0112295A - Método para a fabricação de um artigo moldado tendo um núcleo, dispositivo para a fabricação de um artigo moldado tendo um núcleo, artigo moldado e agregado de artigos moldados - Google Patents

Método para a fabricação de um artigo moldado tendo um núcleo, dispositivo para a fabricação de um artigo moldado tendo um núcleo, artigo moldado e agregado de artigos moldados

Info

Publication number
BR0112295A
BR0112295A BR0112295-9A BR0112295A BR0112295A BR 0112295 A BR0112295 A BR 0112295A BR 0112295 A BR0112295 A BR 0112295A BR 0112295 A BR0112295 A BR 0112295A
Authority
BR
Brazil
Prior art keywords
molded article
core
manufacturing
molding material
puncture member
Prior art date
Application number
BR0112295-9A
Other languages
English (en)
Other versions
BR0112295B1 (pt
Inventor
Yoshiya Kondo
Yukinao Watanabe
Yuichi Ozeki
Original Assignee
Sanwa Kagaku Kenkyusho Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanwa Kagaku Kenkyusho Co filed Critical Sanwa Kagaku Kenkyusho Co
Priority claimed from US10/317,360 external-priority patent/US7811488B2/en
Publication of BR0112295A publication Critical patent/BR0112295A/pt
Publication of BR0112295B1 publication Critical patent/BR0112295B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Press-Shaping Or Shaping Using Conveyers (AREA)

Abstract

"MéTODO PARA A FABRICAçãO DE UM ARTIGO MOLDADO TENDO UM NúCLEO, DISPOSITIVO PARA A FABRICAçãO DE UM ARTIGO MOLDADO TENDO UM NúCLEO, ARTIGO MOLDADO E AGREGADO DE ARTIGOS MOLDADOS". A presente invenção se refere à fabricação, de uma forma eficiente, de um artigo moldado tendo um núcleo e, ao mesmo tempo, a partir de um material de moldagem tal como um grânulo em pó. Com esta finalidade, um método para a fabricação do artigo moldado tendo um núcleo foi desenvolvido, cujo método utiliza um dispositivo de moldagem por compressão, o qual compreende uma matriz de moldagem, membros de punção superior e inferior, onde pelo menos o membro de punção superior, preferivelmente ambos os membros de punção superior e inferior, têm uma construção dupla consistindo de um membro de punção central e um membro de punção externo circundando a periferia externa do membro de punção central, ambos o membro de punção central e o membro de punção externo sendo capazes de desempenhar movimentos de deslocamento bem como operações de compressão. Este método inclui etapas de alimentação separada do material de moldagem para o núcleo e do material de moldagem para a camada externa, uma etapa de moldagem por compressão do material de moldagem para o núcleo e/ou do material de moldagem para a camada externa, e uma etapa de moldagem por compressão final do artigo moldado tendo um núcleo. A invenção também proporciona uma máquina rotativa para a moldagem por compressão, usada para a execução do método. A invenção também proporciona várias características para um artigo moldado tendo um núcleo fabricados pelo método de fabricação acima mencionado. O núcleo pode incluir uma grande quantidade de microcápsulas que são moldes incompletos, ou uma pluralidade de núcleos.
BRPI0112295-9A 2000-06-20 2001-06-20 mÉtodo para a fabricaÇço de um artigo moldado tendo um nécleo, dispositivo para a fabricaÇço de um artigo moldado tendo um nécleo, artigo moldado e agregado de artigos moldados. BR0112295B1 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2000183996 2000-06-20
JP2000387052 2000-12-20
JP2001042787 2001-02-20
JP2001074413 2001-03-15
JP2001098571 2001-03-30
JP2001125690 2001-04-24
PCT/JP2001/005296 WO2001098067A1 (en) 2000-06-20 2001-06-20 Nucleated molded article, method of producing the same, and device for producing the same
US10/317,360 US7811488B2 (en) 2000-06-20 2002-12-12 Method for manufacturing molded article with core

Publications (2)

Publication Number Publication Date
BR0112295A true BR0112295A (pt) 2003-09-02
BR0112295B1 BR0112295B1 (pt) 2011-06-14

Family

ID=32966894

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0112295-9A BR0112295B1 (pt) 2000-06-20 2001-06-20 mÉtodo para a fabricaÇço de um artigo moldado tendo um nécleo, dispositivo para a fabricaÇço de um artigo moldado tendo um nécleo, artigo moldado e agregado de artigos moldados.

Country Status (6)

Country Link
EP (1) EP1302304B1 (pt)
CN (1) CN1315638C (pt)
AU (1) AU2001274575A1 (pt)
BR (1) BR0112295B1 (pt)
CA (1) CA2412173C (pt)
WO (1) WO2001098067A1 (pt)

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* Cited by examiner, † Cited by third party
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KR100463775B1 (ko) * 2000-12-04 2004-12-29 가부시키가이샤 무라타 세이사쿠쇼 분말 공급 장치 및 분말 성형 장치
CN1210142C (zh) 2001-05-07 2005-07-13 株式会社菊水制作所 回转式压缩成型机
CN100410063C (zh) * 2003-11-14 2008-08-13 株式会社三和化学研究所 有核成型品的制造方法
WO2005097041A1 (ja) * 2004-04-09 2005-10-20 Sanwa Kagaku Kenkyusho Co., Ltd. 有核成型品とその製造方法
DK1782944T3 (da) * 2004-08-26 2014-09-01 Kikusui Seisakusho Ltd Maskine til formning med rotationskompression, som anvender et stempel
EP3205337A1 (en) 2005-08-18 2017-08-16 Teijin Pharma Limited Formulation having accurate dose-dividing function
GB0702974D0 (en) * 2007-02-15 2007-03-28 Jagotec Ag Method and apparatus for producing a tablet
CN102458475B (zh) * 2009-05-20 2016-03-30 大日本住友制药株式会社 压制包衣的口腔崩解片
ES2713330T3 (es) 2009-12-11 2019-05-21 Sumitomo Dainippon Pharma Co Ltd Comprimido recubierto en seco que se desintegra oralmente
EP2764989A4 (en) * 2011-10-04 2016-01-20 Sanwa Kagaku Kenkyusho Co POWDER FILLING DEVICE WITH COLLECTING MECHANISM OF EXCESSIVE POWDER AND TURNING PRESSING MACHINE
EP2825375B1 (de) * 2012-03-12 2024-05-01 Nienstedt GmbH Verfahren zum formen von lebensmittelportionen in mehreren aufnahmen
WO2015008825A1 (ja) 2013-07-19 2015-01-22 株式会社三和化学研究所 口腔内崩壊錠
WO2015038854A1 (en) 2013-09-13 2015-03-19 R.P. Scherer Technologies, Llc Encased-pellet tablets
US10064827B2 (en) 2013-12-11 2018-09-04 Roland SAUR-BROSCH Method for the production of a molding
CN104589691B (zh) * 2014-12-22 2016-04-06 泉州众志金刚石工具有限公司 一种金刚石刀头的自动流水线装坯机
DE102015105936B4 (de) * 2015-04-17 2017-07-13 Fette Compacting Gmbh Rotor für eine Rundläuferpresse
TWI690333B (zh) * 2015-06-29 2020-04-11 日商大賽璐股份有限公司 易服用性固態製劑（有核錠）之製造方法及易服用性固態製劑
CN109435315B (zh) * 2018-11-09 2023-06-23 苏州益顺华智能装备有限公司 一种全自动胶饼机
TWI698237B (zh) * 2018-11-22 2020-07-11 陳慧如 多層錠膠體複合成錠方法及製品
CN114425879A (zh) * 2020-10-28 2022-05-03 上海复星星泰医药科技有限公司 一种用于制备包芯片的压片机、包芯片及其制备方法

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JPS52126577A (en) * 1976-04-16 1977-10-24 Kikusui Seisakusho Ltd Lower pounder device in rotary type powder compression forming machine
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JPS5548653A (en) * 1978-10-03 1980-04-07 Kikusui Seisakusho:Kk Nucleus centering test method for rotary nucleated tablet machine
JPS5939499A (ja) * 1982-08-28 1984-03-03 Tokyo Shiyouketsu Kinzoku Kk 圧粉体の成形方法
JPS6160298A (ja) * 1984-08-30 1986-03-27 Kikusui Seisakusho:Kk 回転式有核錠剤機の核錠供給位置自動調節装置
US4710384A (en) * 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
JPH0726074Y2 (ja) * 1989-03-16 1995-06-14 株式会社菊水製作所 ダブル有核錠剤の製造装置
JPH02243158A (ja) * 1989-03-16 1990-09-27 Kikusui Seisakusho:Kk ダブル有核錠剤及びその製造方法
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Also Published As

Publication number Publication date
CA2412173A1 (en) 2002-12-06
CN1315638C (zh) 2007-05-16
EP1302304A1 (en) 2003-04-16
BR0112295B1 (pt) 2011-06-14
EP1302304A4 (en) 2005-12-28
AU2001274575A1 (en) 2002-01-02
EP1302304B1 (en) 2011-12-14
CA2412173C (en) 2010-08-17
CN1437531A (zh) 2003-08-20
WO2001098067A1 (en) 2001-12-27

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Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/06/2001, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 20A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2624 DE 20-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.