BR0114635A - Anticolinérgicos aplicáveis como medicamento bem como processo para a sua preparação - Google Patents

Anticolinérgicos aplicáveis como medicamento bem como processo para a sua preparação

Info

Publication number
BR0114635A
BR0114635A BR0114635-1A BR0114635A BR0114635A BR 0114635 A BR0114635 A BR 0114635A BR 0114635 A BR0114635 A BR 0114635A BR 0114635 A BR0114635 A BR 0114635A
Authority
BR
Brazil
Prior art keywords
preparation
well
anticholinergics
medicine
applicable
Prior art date
Application number
BR0114635-1A
Other languages
English (en)
Inventor
Helmut Meissner
Gerd Morschhaeuser
Michael Paul Pieper
Gerald Pohl
Richard Reichl
Georg Speck
Rolf Banholzer
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BR0114635A publication Critical patent/BR0114635A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

"ANTICOLINéRGICOS APLICáVEIS COMO MEDICAMENTO BEM COMO PROCESSO PARA A SUA PREPARAçãO". A presente invenção refere-se a novos anticolinérgicos da fórmula geral (I), na qual A, X^ -^ e os radicais R^ 1^, R^ 2^, R^ 3^, R^ 4^, R^ 5^, R^ 6^ e R^ 7^ podem ter os significados mencionados nas reivindicações e na descrição, processos para a sua preparação bem como sua aplicação como medicamentos.
BR0114635-1A 2000-10-14 2001-09-28 Anticolinérgicos aplicáveis como medicamento bem como processo para a sua preparação BR0114635A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050994A DE10050994A1 (de) 2000-10-14 2000-10-14 Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung
PCT/EP2001/011226 WO2002032899A1 (de) 2000-10-14 2001-09-28 Neue als arzneimittel einsetzbare anticholinergika sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BR0114635A true BR0114635A (pt) 2004-02-10

Family

ID=7659808

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114635-1A BR0114635A (pt) 2000-10-14 2001-09-28 Anticolinérgicos aplicáveis como medicamento bem como processo para a sua preparação

Country Status (37)

Country Link
EP (2) EP1382606A3 (pt)
JP (2) JP4109106B2 (pt)
KR (1) KR100830359B1 (pt)
CN (1) CN1275962C (pt)
AR (1) AR035589A1 (pt)
AT (1) ATE259805T1 (pt)
AU (2) AU1397502A (pt)
BG (1) BG66225B1 (pt)
BR (1) BR0114635A (pt)
CA (1) CA2425557C (pt)
DE (2) DE10050994A1 (pt)
DK (1) DK1325001T3 (pt)
EA (1) EA005816B1 (pt)
EC (1) ECSP034542A (pt)
EE (1) EE05179B1 (pt)
ES (1) ES2215147T3 (pt)
HR (1) HRP20030278B1 (pt)
HU (1) HUP0301203A3 (pt)
IL (2) IL155334A0 (pt)
ME (1) MEP39908A (pt)
MX (1) MXPA03003160A (pt)
MY (1) MY127144A (pt)
NO (1) NO328207B1 (pt)
NZ (1) NZ525836A (pt)
PE (1) PE20020433A1 (pt)
PL (1) PL207311B1 (pt)
PT (1) PT1325001E (pt)
RS (1) RS50464B (pt)
SA (1) SA01220414B1 (pt)
SI (1) SI1325001T1 (pt)
SK (1) SK287138B6 (pt)
TR (1) TR200400376T4 (pt)
TW (1) TWI306098B (pt)
UA (1) UA73804C2 (pt)
UY (1) UY26958A1 (pt)
WO (1) WO2002032899A1 (pt)
ZA (1) ZA200302914B (pt)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10200943A1 (de) * 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern
US7405224B2 (en) 2002-01-31 2008-07-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions
DE10203753A1 (de) * 2002-01-31 2003-08-14 Boehringer Ingelheim Pharma Neue Xanthencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
DE10256317A1 (de) * 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Betamimetika und ein neues Anticholinergikum
RS50735B (sr) * 2002-04-12 2010-08-31 Boehringer Ingelheim Pharma Gmbh. & Co.Kg. Medikamenti koji sadrže betamimetik lekove i novi lek antiholinesteraze
DE10216429A1 (de) * 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Arzneimittel enthaltend Steroide und ein neues Anticholinergikum
US7417051B2 (en) 2002-04-12 2008-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising betamimetics and a novel anticholinergic
US7084153B2 (en) 2002-04-12 2006-08-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising steroids and a novel anticholinergic
DE10224091A1 (de) * 2002-05-31 2003-12-11 Boehringer Ingelheim Pharma Technisches Verfahren zur Herstellung von Tropenol
DE10230769A1 (de) * 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und PDE-IV-Inhibitoren
DE10230750A1 (de) * 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholonergika und NK1-Rezeptor-Antagonisten
DE10230751A1 (de) 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern
AU2003245989A1 (en) * 2002-07-09 2004-01-23 Boehringer Ingelheim Pharma Gmbh And Co. Kg Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
PT1530464E (pt) * 2002-08-14 2008-08-28 Boehringer Ingelheim Pharma Formulação de aerossol para a inalação contendo um agente anticolinérgico
US7244742B2 (en) 2002-08-17 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co Kg Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic
DE10237739A1 (de) * 2002-08-17 2004-02-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
DE10323966A1 (de) * 2003-05-27 2004-12-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen
US7332175B2 (en) 2003-05-27 2008-02-19 Boehringer Ingelheim International Gmbh Long-acting drug combinations for the treatment of respiratory complaints
US7273603B2 (en) * 2003-07-11 2007-09-25 Boehringer Ingelheim International Gmbh HFC solution formulations containing an anticholinergic
DE10331350A1 (de) * 2003-07-11 2005-01-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation enthaltend ein neues Anticholinergikum
US7462367B2 (en) 2003-07-11 2008-12-09 Boehringer Ingelheim International Gmbh Anticholinergic powder formulations for inhalation
JP2007500147A (ja) * 2003-07-28 2007-01-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ステロイド及びフルオレンカルボン酸エステルを含有する吸入用医薬品
CA2533786A1 (en) * 2003-07-28 2005-02-17 Boehringer Ingelheim International Gmbh Medicaments comprising pde iv inhibitors and a novel anticholinergic and their use for treating respiratory disorders
ATE420641T1 (de) * 2003-07-28 2009-01-15 Boehringer Ingelheim Int Medikamente zur inhalation mit betamimetika und einem anticholinergikum
PT1651270E (pt) * 2003-07-29 2007-04-30 Boehringer Ingelheim Int Medicamentos para inalação compreendendo betamiméticos e um anticolinérgico
WO2005013994A1 (en) * 2003-07-31 2005-02-17 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising anticholinergics and a betamimetic
EP1504756A1 (en) * 2003-08-06 2005-02-09 Kyowa Hakko Kogyo Co., Ltd Medicament compositions comprising a heterocyclic compound and an anticholinergic
DE10345065A1 (de) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
JP2007517820A (ja) * 2004-01-09 2007-07-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング スコピンエステル及びニコチンアミド誘導体を基にした新規な医薬組成物
US20050186175A1 (en) * 2004-02-20 2005-08-25 Boehringer Ingelheim International Gmbh Pharmaceutical compositions based on benzilic acid esters and soluble TNF receptor fusion proteins
US7507745B2 (en) 2004-02-20 2009-03-24 Boehringer Ingelheim International Gmbh Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins
CA2552903A1 (en) * 2004-02-20 2005-09-01 Boehringer Ingelheim International Gmbh Pharmaceutical compositions based on anticholinergics and pegsunercept
DE102004016179A1 (de) * 2004-03-30 2005-10-20 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von proliferativen Prozessen
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ES2322148T3 (es) * 2004-08-11 2009-06-17 BOEHRINGER INGELHEIM PHARMA GMBH &amp; CO. KG Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias.
DE102004056578A1 (de) * 2004-11-23 2006-05-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalative Arzneimittel enthaltend ein neues Anticholinergikum, Formoterol und ein Steroid
WO2006087316A1 (en) * 2005-02-16 2006-08-24 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising anticholinergics and etiprednol
JP2008532973A (ja) * 2005-03-09 2008-08-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗コリン作用薬とｐｄｅ５−阻害剤に基づく新規な医薬組成物
JP2008542332A (ja) * 2005-05-31 2008-11-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患治療用新規医薬組成物
EP1898894A1 (en) * 2005-06-17 2008-03-19 Boehringer Ingelheim International GmbH Mrp iv inhibitors for the treatment of respiratory diseases
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
EP1917253B1 (de) 2005-08-15 2015-01-07 Boehringer Ingelheim International Gmbh Verfahren zur herstellung von betamimetika
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
DE102005055963A1 (de) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055961A1 (de) * 2005-11-24 2007-05-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
DE102005055957A1 (de) * 2005-11-24 2007-07-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
JP2010500318A (ja) 2006-08-07 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療用医薬組成物
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
SI2124944T1 (sl) 2007-03-14 2012-05-31 Ranbaxy Lab Ltd Derivati pirazolo b piridina kot inhibitorji fosfodiesteraze
ES2569359T3 (es) 2007-07-06 2016-05-10 Vectura Delivery Devices Limited Inhalador
CA2688669A1 (en) * 2007-07-18 2009-01-22 Boehringer Ingelheim International Gmbh New combinations for the treatment of respiratory diseases
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2082768A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082771A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082766A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Blister Strip Coil Forming
EP2082772A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082767A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
GB0918450D0 (en) 2009-10-21 2009-12-09 Innovata Ltd Composition
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
HRP20181980T1 (hr) 2012-12-21 2019-01-25 Boehringer Ingelheim Vetmedica Gmbh Ciklezonid za liječenje dišnih puteva kod konja
ES2706757T3 (es) 2012-12-21 2019-04-01 Boehringer Ingelheim Vetmedica Gmbh Formulación farmacéutica que comprende ciclesonida
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
WO2015193213A1 (en) * 2014-06-18 2015-12-23 Boehringer Ingelheim Vetmedica Gmbh Muscarinic antagonists and combinations thereof for the treatment of airway disease in horses
CA2997541C (en) * 2015-09-04 2022-01-11 Janssen Pharmaceutica Nv Therapeutic compounds for pain and synthesis thereof
CN113292574B (zh) * 2020-02-21 2022-05-03 四川大学 一类手性多环的托品烷化合物及其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln

Also Published As

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AR035589A1 (es) 2004-06-16
CA2425557A1 (en) 2003-04-11
AU1397502A (en) 2002-04-29
IL155334A (en) 2009-02-11
TWI306098B (en) 2009-02-11
MY127144A (en) 2006-11-30
CN1275962C (zh) 2006-09-20
CN1468236A (zh) 2004-01-14
MEP39908A (en) 2011-02-10
AU2002213975B2 (en) 2006-11-09
EE200300151A (et) 2003-06-16
RS50464B (sr) 2010-03-02
ECSP034542A (es) 2003-06-25
UA73804C2 (en) 2005-09-15
ZA200302914B (en) 2003-11-14
IL155334A0 (en) 2003-11-23
PL207311B1 (pl) 2010-11-30
HUP0301203A3 (en) 2006-05-29
HRP20030278B1 (en) 2006-02-28
HUP0301203A2 (hu) 2003-10-28
YU29503A (sh) 2006-03-03
EP1325001B1 (de) 2004-02-18
JP2004511557A (ja) 2004-04-15
EP1382606A3 (de) 2004-10-13
EP1382606A2 (de) 2004-01-21
WO2002032899A1 (de) 2002-04-25
PT1325001E (pt) 2004-07-30
NO20031693L (no) 2003-05-28
PL360673A1 (en) 2004-09-20
SA01220414B1 (ar) 2007-01-20
EA200300459A1 (ru) 2003-10-30
EP1325001A1 (de) 2003-07-09
KR20030041165A (ko) 2003-05-23
JP2008120834A (ja) 2008-05-29
MXPA03003160A (es) 2005-09-09
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NO328207B1 (no) 2010-01-11
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ATE259805T1 (de) 2004-03-15
EE05179B1 (et) 2009-06-15
SK287138B6 (sk) 2010-01-07
TR200400376T4 (tr) 2004-03-22
CA2425557C (en) 2007-11-13
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ES2215147T3 (es) 2004-10-01
JP4109106B2 (ja) 2008-07-02
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