BR0214455A - Derivados benzotiazol - Google Patents

Derivados benzotiazol

Info

Publication number: BR0214455A
Authority: BR; Brazil
Prior art keywords: optionally substituted; lower alkyl; phenyl; thiophenyl; benzo
Prior art date: 2001-11-27

Application number

BR0214455-7A

Other languages

English (en)

Portuguese (pt)

Inventor

Alexander Flohr

Roland Jakob-Roetne

Roger David Norcross

Claus Riemer

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-27

Filing date

2002-11-18

Publication date

2004-11-03

2002-11-18 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2004-11-03 Publication of BR0214455A publication Critical patent/BR0214455A/pt

Links

IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 8
229910052736 halogen Inorganic materials 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
-1 (phenyl) -pyridinyl Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
101150051188 Adora2a gene Proteins 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004305 biphenyl Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000437 thiazol-2-yl group Chemical group [H]C1=C([H])N=C(*)S1 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Toxicology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

BR0214455-7A 2001-11-27 2002-11-18 Derivados benzotiazol BR0214455A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01127442		2001-11-27
PCT/EP2002/012907 WO2003045385A1 (en)	2001-11-27	2002-11-18	Benzothiazole derivatives

Publications (1)

Publication Number	Publication Date
BR0214455A true BR0214455A (pt)	2004-11-03

Family

ID=8179277

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR0214455-7A BR0214455A (pt)	2001-11-27	2002-11-18	Derivados benzotiazol

Country Status (21)

Country	Link
US (1)	US6596718B1 (de)
EP (1)	EP1450796B1 (de)
JP (1)	JP4216193B2 (de)
KR (1)	KR100613197B1 (de)
CN (1)	CN1325052C (de)
AR (1)	AR037418A1 (de)
AT (1)	ATE391505T1 (de)
AU (1)	AU2002352045B2 (de)
BR (1)	BR0214455A (de)
CA (1)	CA2467825A1 (de)
DE (1)	DE60226063T2 (de)
ES (1)	ES2303558T3 (de)
GT (1)	GT200200240A (de)
MX (1)	MXPA04004982A (de)
PA (1)	PA8558201A1 (de)
PE (1)	PE20030735A1 (de)
PL (1)	PL370978A1 (de)
RU (1)	RU2293083C2 (de)
TW (1)	TW200408391A (de)
UY (1)	UY27551A1 (de)
WO (1)	WO2003045385A1 (de)

Families Citing this family (34)

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WO2008011131A2 (en) *	2006-07-21	2008-01-24	Takeda Pharmaceutical Company Limited	Amide compounds
US6678828B1 (en) *	2002-07-22	2004-01-13	Vormetric, Inc.	Secure network file access control system
PT1636223E (pt)	2003-05-19	2008-05-06	F Hoffmann-La Roche Ag	Derivados de benzotiazole como ligandos de receptores da adenosina
WO2005033079A1 (ja) *	2003-09-30	2005-04-14	Eisai Co., Ltd.	ヘテロ環化合物を含有する新規な抗真菌剤
EP1677791A4 (de)	2003-10-31	2007-08-15	Takeda Pharmaceutical	Stickstoffhaltige kondensierte heterocyclische verbindungen
EP1710233A4 (de) *	2004-01-28	2009-07-15	Kissei Pharmaceutical	Neues benzofuranderivat, dieses enthaltende medizinische zusammensetzung und anwendungen davon
WO2005096098A2 (en) *	2004-03-30	2005-10-13	Carl Zeiss Smt Ag	Projection objective, projection exposure apparatus and reflective reticle for microlithography
CN1989117B (zh) *	2004-07-22	2011-01-19	弗·哈夫曼-拉罗切有限公司	取代的苯并噻唑
US20090227799A1 (en) *	2004-08-09	2009-09-10	Kazutaka Nakamoto	Novel Antimalarial Agent Containing Heterocyclic Compound
EP1864980A4 (de)	2005-03-30	2010-08-18	Eisai R&D Man Co Ltd	Ein pyridinderivat enthaltendes antipilzmittel
WO2006115134A1 (ja) *	2005-04-22	2006-11-02	Kissei Pharmaceutical Co., Ltd.	新規なベンゾフラン誘導体、それを含有する医薬組成物およびそれらの用途
TWI385169B (zh) *	2005-10-31	2013-02-11	Eisai R&D Man Co Ltd	經雜環取代之吡啶衍生物及含有彼之抗真菌劑
EP2065377B1 (de) *	2006-09-21	2011-11-23	Eisai R&D Management Co., Ltd.	Durch einen heteroarylring substituiertes pyridinderivat und antipilzmittel, das dieses enthält
DE602007006990D1 (de)	2006-12-07	2010-07-15	Hoffmann La Roche	Spiropiperidinderivate als antagonisten des via-rezeptors
BRPI0721138A2 (pt)	2006-12-22	2014-04-01	Hoffmann La Roche	Derivados de espiro-piperidina
CN101563323B (zh)	2006-12-22	2012-07-04	弗·哈夫曼-拉罗切有限公司	螺-哌啶衍生物
TW200841879A (en)	2007-04-27	2008-11-01	Eisai R&D Man Co Ltd	Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
WO2008136279A1 (ja) *	2007-04-27	2008-11-13	Eisai R & D Management Co., Ltd.	ヘテロ環置換ピリジン誘導体の塩またはその結晶
US8513287B2 (en)	2007-12-27	2013-08-20	Eisai R&D Management Co., Ltd.	Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) *	2008-10-24	2012-05-29	Eisai R&D Management Co., Ltd	Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
EP2723718A1 (de)	2011-06-24	2014-04-30	Amgen Inc.	Trpm8-antagonisten und ihre verwendung bei behandlungen
JP2014527511A (ja)	2011-06-24	2014-10-16	アムジエン・インコーポレーテツド	Ｔｒｐｍ８拮抗剤及び治療におけるそれらの使用
WO2013042137A1 (en) *	2011-09-19	2013-03-28	Aurigene Discovery Technologies Limited	Bicyclic heterocycles as irak4 inhibitors
US8940742B2 (en)	2012-04-10	2015-01-27	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
US8952009B2 (en)	2012-08-06	2015-02-10	Amgen Inc.	Chroman derivatives as TRPM8 inhibitors
US9751888B2 (en)	2013-10-04	2017-09-05	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
PT3052485T (pt)	2013-10-04	2021-10-22	Infinity Pharmaceuticals Inc	Compostos heterocíclicos e suas utilizações
MX382033B (es)	2014-03-19	2025-03-13	Infinity Pharmaceuticals Inc	Compuestos heterocíclicos para utilizarlos en el tratamiento de trastornos mediados por pi3k-gamma.
WO2016054491A1 (en)	2014-10-03	2016-04-07	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
WO2017048702A1 (en)	2015-09-14	2017-03-23	Infinity Pharmaceuticals, Inc.	Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
WO2017161116A1 (en)	2016-03-17	2017-09-21	Infinity Pharmaceuticals, Inc.	Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
WO2017214269A1 (en)	2016-06-08	2017-12-14	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
AU2017360939B2 (en) *	2016-11-18	2022-03-03	Merck Sharp & Dohme Corp.	Indazole derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2
WO2020048583A1 (en) *	2018-09-04	2020-03-12	F. Hoffmann-La Roche Ag	Benzothiazole compounds for the treatment of autoimmune diseases

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GB8717068D0 (en) *	1987-07-20	1987-08-26	Fujisawa Pharmaceutical Co	Nitric ester derivative
AU2001281817B2 (en) *	2000-06-21	2005-11-24	F. Hoffmann-La Roche Ag	Benzothiazole derivatives

2002
- 2002-11-18 US US10/298,347 patent/US6596718B1/en not_active Expired - Fee Related
- 2002-11-18 RU RU2004119438/04A patent/RU2293083C2/ru not_active IP Right Cessation
- 2002-11-18 PL PL02370978A patent/PL370978A1/xx not_active Application Discontinuation
- 2002-11-18 AU AU2002352045A patent/AU2002352045B2/en not_active Ceased
- 2002-11-18 JP JP2003546887A patent/JP4216193B2/ja not_active Expired - Fee Related
- 2002-11-18 WO PCT/EP2002/012907 patent/WO2003045385A1/en not_active Ceased
- 2002-11-18 DE DE60226063T patent/DE60226063T2/de not_active Expired - Lifetime
- 2002-11-18 AT AT02787718T patent/ATE391505T1/de active
- 2002-11-18 CN CNB028236041A patent/CN1325052C/zh not_active Expired - Fee Related
- 2002-11-18 KR KR1020047007929A patent/KR100613197B1/ko not_active Expired - Fee Related
- 2002-11-18 ES ES02787718T patent/ES2303558T3/es not_active Expired - Lifetime
- 2002-11-18 EP EP02787718A patent/EP1450796B1/de not_active Expired - Lifetime
- 2002-11-18 CA CA002467825A patent/CA2467825A1/en not_active Abandoned
- 2002-11-18 MX MXPA04004982A patent/MXPA04004982A/es active IP Right Grant
- 2002-11-18 BR BR0214455-7A patent/BR0214455A/pt not_active IP Right Cessation
- 2002-11-22 PA PA20028558201A patent/PA8558201A1/es unknown
- 2002-11-22 GT GT200200240A patent/GT200200240A/es unknown
- 2002-11-22 TW TW091134083A patent/TW200408391A/zh unknown
- 2002-11-25 PE PE2002001132A patent/PE20030735A1/es not_active Application Discontinuation
- 2002-11-25 AR ARP020104516A patent/AR037418A1/es unknown
- 2002-11-26 UY UY27551A patent/UY27551A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1450796A1 (de)	2004-09-01
UY27551A1 (es)	2003-06-30
RU2004119438A (ru)	2006-01-10
MXPA04004982A (es)	2004-08-11
WO2003045385A1 (en)	2003-06-05
AU2002352045B2 (en)	2006-08-17
PL370978A1 (en)	2005-06-13
AR037418A1 (es)	2004-11-10
KR20040062968A (ko)	2004-07-09
CA2467825A1 (en)	2003-06-05
AU2002352045A1 (en)	2003-06-10
CN1325052C (zh)	2007-07-11
KR100613197B1 (ko)	2006-08-21
ATE391505T1 (de)	2008-04-15
DE60226063D1 (en)	2008-05-21
US6596718B1 (en)	2003-07-22
PE20030735A1 (es)	2003-08-29
JP2005526007A (ja)	2005-09-02
EP1450796B1 (de)	2008-04-09
DE60226063T2 (de)	2009-05-20
GT200200240A (es)	2003-07-30
ES2303558T3 (es)	2008-08-16
JP4216193B2 (ja)	2009-01-28
TW200408391A (en)	2004-06-01
CN1731999A (zh)	2006-02-08
RU2293083C2 (ru)	2007-02-10
PA8558201A1 (es)	2003-09-05

Legal Events

Date	Code	Title	Description
2011-03-15	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2014-04-15	B08L	Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]	Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 10A E 11A ANUIDADES.
2020-11-10	B08I	Publication cancelled [chapter 8.9 patent gazette]	Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2258 DE 15/04/2014 POR TER SIDO INDEVIDA.
2020-11-17	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 10A, 11A, 12A, 13A, 14A, 15A, 16A E 17A ANUIDADES.
2021-03-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BR0214455A (pt)	2004-11-03	Derivados benzotiazol
BR0115580A (pt)	2003-09-09	Derivados de 3-aroilindol e a utilizaçao dos mesmos como agonistas dos receptores cb2
BR0306150A (pt)	2004-10-19	Composto, uso de um composto, e, composição farmacêutica
BR9907300A (pt)	2000-10-24	Inibidores do fator xa oxoaza-heterociclila substituìdos
BRPI0309534B8 (pt)	2021-05-25	derivados de triazol como antagonistas do receptor de taquicinina, seu uso, e composição farmacêutica
BRPI0407508A (pt)	2006-02-14	derivados de bifenila
BR9810829A (pt)	2000-07-25	Composto, processo para preparar o mesmo, composição, uso de um composto ou um sal farmaceuticamente aceitável do mesmo ou uma composição, e, processo de tratamento de uma condição
BR0212185A (pt)	2004-10-05	Compostos e métodos para a preparação de compostos
BR0112582A (pt)	2003-05-20	Sulfonamidas de ciclilamina como agonistas de receptores beta-3 adrenérgicos
BRPI0413232B8 (pt)	2021-05-25	composto tendo atividade inibitória contra transportador dependente de sódio, composição farmacêutica compreendendo o composto, uso do composto na preparação de um medicamento e processo para a preparação do composto
BR0317645A (pt)	2005-12-06	Composto ou um sal deste, composição farmacêutica, uso de um composto, e, método de tratamento e/ou profilaxia de uma doença inflamatória e/ou alérgica ou deterioração cognitiva em um mamìfero
BR0210538A (pt)	2004-06-22	Derivados de 5-halotriptamina usados como ligantes dos receptores de serotonina 5-ht6 e/ou 5-ht7
BR0211206A (pt)	2004-07-13	Derivados de 8-metóxi-(1,2,4)triazolo(1, 5-a)piridina e seus usos como ligantes do receptor de adenosina
SE0104334D0 (sv)	2001-12-19	Therapeutic agents
BR0008489A (pt)	2002-02-05	Derivados de fenil- e piridinila
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BRPI0409110A (pt)	2006-03-28	derivados de 4-(4-heterociclilalcoxi)fenil-1-(heterociclil-carboni l)piridina e compostos relacionados como antagonistas de histamina h3 para o tratamento de doenças neurológicas tais como alzheimer
BRPI0507495A (pt)	2007-07-10	composto, composição farmacêutica, uso do composto método para o tratamento de distúrbios mediados por mglur5, e, método para inibir a ativação de receptores de mglur5
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BRPI9913542B8 (pt)	2021-05-25	derivados de dihidrobenzodioxina carboxamida e dihidrobenzodioxina cetona como antagonistas do receptor 5-ht4 bem como composição farmacêutica, processo para a preparação dos referidos derivados e uso dos mesmos
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BR0308145A (pt)	2004-12-07	Composto, composição farmacêutica, uso de um composto, e, processo para a preparação de um composto
DE60033964D1 (de)	2007-04-26	Phenoxypropanolamin-derivate, ihre herstellung und therapeutische verwendung
BR0109816A (pt)	2003-01-21	Composto, processo para prepará-lo, uso do mesmo, composição farmacêutica, e, métodos para o tratamento da dor, papa o tratamento de distúrbios gastrointestinais, e para o tratamento de lesões espinhais
DE69838662D1 (de)	2007-12-20	Morphinanderivate und ihre medizinische Anwendung