BR0307400A - Compostos de porfirina platina solúveis em água com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno - Google Patents

Compostos de porfirina platina solúveis em água com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno

Info

Publication number
BR0307400A
BR0307400A BR0307400-5A BR0307400A BR0307400A BR 0307400 A BR0307400 A BR 0307400A BR 0307400 A BR0307400 A BR 0307400A BR 0307400 A BR0307400 A BR 0307400A
Authority
BR
Brazil
Prior art keywords
benign
treatment
water soluble
selectivity
platinum compounds
Prior art date
Application number
BR0307400-5A
Other languages
English (en)
Inventor
Karl-Christian Bart
G Nther Bernhardt
Henry Brunner
Christian Lottner
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of BR0307400A publication Critical patent/BR0307400A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyethers (AREA)

Abstract

"COMPOSTOS DE PORFIRINA PLATINA SOLúVEIS EM áGUA COM ALTA SELETIVIDADE DE TUMOR E SEU USO PARA O TRATAMENTO DE DOENçAS DE TUMOR BENIGNO E MALIGNO". A presente invenção refere-se a novos compostos de porfirina platina solúveis em água do tipo derivados de tetraarilporfirina platina ou do tipo derivados de hematoporfirina platina com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno. Em particular, os compostos são apropriados para terapia antitumor fotodinâmica.
BR0307400-5A 2002-02-01 2003-01-29 Compostos de porfirina platina solúveis em água com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno BR0307400A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35358502P 2002-02-01 2002-02-01
PCT/EP2003/000874 WO2003064424A2 (en) 2002-02-01 2003-01-29 Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases

Publications (1)

Publication Number Publication Date
BR0307400A true BR0307400A (pt) 2004-12-21

Family

ID=27663224

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307400-5A BR0307400A (pt) 2002-02-01 2003-01-29 Compostos de porfirina platina solúveis em água com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno

Country Status (18)

Country Link
US (1) US7087214B2 (pt)
EP (1) EP1470139A2 (pt)
JP (1) JP2005522429A (pt)
KR (1) KR20040083098A (pt)
CN (1) CN1303090C (pt)
AR (1) AR038479A1 (pt)
BR (1) BR0307400A (pt)
CA (1) CA2418410A1 (pt)
HR (1) HRP20040788A2 (pt)
MX (1) MXPA04007443A (pt)
NO (1) NO20043650L (pt)
NZ (1) NZ534541A (pt)
PL (1) PL373346A1 (pt)
RU (1) RU2004126637A (pt)
TW (1) TWI233929B (pt)
UA (1) UA78007C2 (pt)
WO (1) WO2003064424A2 (pt)
ZA (1) ZA200405925B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
EP1950217A1 (en) * 2007-01-26 2008-07-30 Université de Neuchâtel Organometallic compounds for the treatment of cancer
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
WO2011089509A1 (en) * 2010-01-22 2011-07-28 Council Of Scientific & Industrial Research A process for the preparation of novel porphyrin derivatives and their use as pdt agents and fluorescence probes
CN102408452B (zh) * 2011-12-13 2014-09-03 中山大学 四吡啶基卟啉桥联十字形四核铂配合物及其制备方法和抗肿瘤活性
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
US11661433B2 (en) 2018-05-09 2023-05-30 Virginia Commonwealth University Near-IR activatable fluorescent small molecules with dual modes of cytotoxicity
CN109251206B (zh) * 2018-09-21 2022-02-08 上海大学 水溶性铂-卟啉配合物及其制备方法
CN110028513B (zh) * 2019-04-30 2020-12-11 北京太阳升高科医药研究股份有限公司 卟啉衍生物及声敏剂
CN110590852B (zh) * 2019-08-29 2022-12-09 合肥学院 一种具有抗肿瘤活性的铂配合物及其制备方法
CN120381439B (zh) * 2025-02-24 2026-04-24 苏州大学 一种基于吡啶基卟啉的聚乙二醇化的纳米颗粒及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0615545B2 (ja) * 1984-10-01 1994-03-02 東洋薄荷工業株式会社 金属フェオホーバイド誘導体および金属ポルフィリン誘導体
ZA86704B (en) 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
AU603999B2 (en) * 1985-10-23 1990-12-06 Photochemical Co., Ltd. Porphyrin derivatives, and their production and use
DE19824653A1 (de) 1998-02-25 1999-08-26 Schering Ag Nekrose-affine Verbindungen und ihre Verwendung zur Herstellung von Präparaten zur Pharmakotherapie

Also Published As

Publication number Publication date
CA2418410A1 (en) 2003-08-01
CN1639178A (zh) 2005-07-13
TW200305571A (en) 2003-11-01
TWI233929B (en) 2005-06-11
RU2004126637A (ru) 2006-02-10
AR038479A1 (es) 2005-01-19
JP2005522429A (ja) 2005-07-28
NZ534541A (en) 2005-10-28
PL373346A1 (en) 2005-08-22
US7087214B2 (en) 2006-08-08
KR20040083098A (ko) 2004-09-30
WO2003064424A2 (en) 2003-08-07
EP1470139A2 (en) 2004-10-27
US20040023942A1 (en) 2004-02-05
HRP20040788A2 (en) 2004-12-31
UA78007C2 (en) 2007-02-15
HK1078585A1 (en) 2006-03-17
ZA200405925B (en) 2004-09-07
CN1303090C (zh) 2007-03-07
MXPA04007443A (es) 2004-10-11
WO2003064424A3 (en) 2004-01-15
NO20043650L (no) 2004-10-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010.