DK0906758T3 - Zink-phthalocyaniner og tilsvarende konjugater, deres frembingelse og anvendelse i fotodynamisk terapi og som diagnostiske midler - Google Patents

Zink-phthalocyaniner og tilsvarende konjugater, deres frembingelse og anvendelse i fotodynamisk terapi og som diagnostiske midler

Info

Publication number
DK0906758T3
DK0906758T3 DK98115036.0T DK98115036T DK0906758T3 DK 0906758 T3 DK0906758 T3 DK 0906758T3 DK 98115036 T DK98115036 T DK 98115036T DK 0906758 T3 DK0906758 T3 DK 0906758T3
Authority
DK
Denmark
Prior art keywords
production
photodynamic therapy
diagnostic agents
zinc phthalocyanines
similar conjugates
Prior art date
Application number
DK98115036.0T
Other languages
English (en)
Inventor
Gabrio Roncucci
Donata Dei
Filippis Maria Paola De
Lia Fantetti
Ilaria Masini
Barbara Cosimelli
Giulio Jori
Original Assignee
Molteni & C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molteni & C filed Critical Molteni & C
Application granted granted Critical
Publication of DK0906758T3 publication Critical patent/DK0906758T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK98115036.0T 1997-08-14 1998-08-11 Zink-phthalocyaniner og tilsvarende konjugater, deres frembingelse og anvendelse i fotodynamisk terapi og som diagnostiske midler DK0906758T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001940A IT1294325B1 (it) 1997-08-14 1997-08-14 Zinco-ftalocianine e relativi coniugati, preparazione e uso nella terapia fotodinamica e come diagnostici

Publications (1)

Publication Number Publication Date
DK0906758T3 true DK0906758T3 (da) 2011-07-11

Family

ID=11377772

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98115036.0T DK0906758T3 (da) 1997-08-14 1998-08-11 Zink-phthalocyaniner og tilsvarende konjugater, deres frembingelse og anvendelse i fotodynamisk terapi og som diagnostiske midler

Country Status (10)

Country Link
US (1) US5965598A (da)
EP (1) EP0906758B1 (da)
AT (1) ATE506057T1 (da)
CA (1) CA2245066C (da)
CY (1) CY1111832T1 (da)
DE (1) DE69842227D1 (da)
DK (1) DK0906758T3 (da)
ES (1) ES2365383T3 (da)
IT (1) IT1294325B1 (da)
PT (1) PT906758E (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6609014B1 (en) 1999-04-14 2003-08-19 Qlt Inc. Use of PDT to inhibit intimal hyperplasia
US7122568B1 (en) 1999-11-17 2006-10-17 Qlt, Inc. Use of low-dose PDT to inhibit restenosis
CA2391389A1 (en) * 1999-11-17 2001-05-25 Qlt Inc. Use of pdt to inhibit intimal hyperplasia
CA2394891A1 (en) * 1999-12-08 2001-06-14 Michael John Cook Substituted phthalocyanines and their precursors
PT1164135E (pt) * 2000-06-15 2004-06-30 Molteni & C Frat Alitti Soc Es Metal-ftalocianinas substituidas sua preparacao e utilizacao
WO2002053570A1 (en) * 2001-01-05 2002-07-11 Seung-Yong Lee Paramagnetic metal-phthalocyanine complex compounds and contrast agent using the same
EP1381611B1 (en) * 2001-03-21 2005-06-22 L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI Metal substituted non centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic therapy and in vivo diagnostic
GB0113899D0 (en) 2001-06-07 2001-08-01 Photocure Asa Photodynamic therapy lamp
IL161650A0 (en) * 2001-10-29 2004-09-27 Molteni & C Dei Flii Alittisoc Separation of regioisomers of metal phthalocyanines
ES2244694T3 (es) * 2002-04-25 2005-12-16 L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI Composiciones antibacterianas que comprenden analogos de metal ftalocianina.
ITFI20020200A1 (it) 2002-10-21 2004-04-22 Molteni & C Dei Flii Alitti S P A Societa L Porfirine meso-sostituite.
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
ITFI20030063A1 (it) * 2003-03-11 2004-09-12 Molteni & C Metallo ftalocianine boronate, loro preparazione, composizioni
CA2541385C (en) * 2003-09-05 2013-11-19 The Ohio State University Research Foundation Nanoparticulate probe for in vivo monitoring of tissue oxygenation
US8066973B2 (en) * 2003-09-05 2011-11-29 The Ohio State University Research Foundation Nanoparticulate probe for in vivo monitoring of tissue oxygenation
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
US7153956B2 (en) 2004-08-09 2006-12-26 Silverbrook Research Pty Ltd Cyanine dye having multifunctional peripheral groups
ITFI20050092A1 (it) * 2005-05-05 2006-11-06 Molteni & C Derivati ftalocianinici, processo per la loro preparazione, composizioni farmaceutiche che li contengono e loro uso
ITFI20050093A1 (it) * 2005-05-05 2006-11-06 Molteni & C Processo per la preparazione di cloruri di derivati ftalocianinici comprendenti almeno un gruppo ammonio quaternario
JP2009500462A (ja) * 2005-06-29 2009-01-08 エル.モルテニ アンド シー.デイ フラテッリ アリッチ ソシエタ’ディ エセルチヅィオ ソシエタ ペル アチオニ 自己滅菌性製品
EP1904060B1 (en) * 2005-06-29 2011-06-01 L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio Societa' Per Azioni Use of phthalocyanine derivates for the non-photodynamic treatment of diseases
WO2007009101A2 (en) * 2005-07-14 2007-01-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Tetraazaporphyrin-based compounds and their uses
JP5066417B2 (ja) * 2006-09-27 2012-11-07 株式会社日本触媒 フタロシアニン化合物およびその製造方法
US7645875B2 (en) * 2006-12-19 2010-01-12 Xerox Corporation Colorant compounds
EP2072584B1 (de) * 2007-12-17 2011-05-11 ILFORD Imaging Switzerland GmbH Phthalocyanin-Farbstoffe, ihre Herstellung und Verwendung
IT1395907B1 (it) 2009-07-30 2012-11-02 Molteni E C Dei Flii Alitti Societa Di Esercizio Spa L Derivato ftalocianinico costituito da una miscela di quattro isomeri
ITFI20110166A1 (it) * 2011-08-05 2013-02-06 Molteni & C Nuovi fotosensibilizzanti ad uso terapeutico.
KR101385196B1 (ko) 2012-05-17 2014-04-14 주식회사 유니크메디케어 광 조사를 이용한 광감각제―펩타이드를 유효성분으로 포함하는 발모 개선 또는 촉진용 조성물 및 이를 이용한 방법
CN102702210B (zh) * 2012-06-01 2014-09-10 福州大学 含哌嗪乙氧基修饰基团的酞菁金属配合物的应用
CN102675325B (zh) * 2012-06-01 2014-06-25 福州大学 含哌嗪乙氧基修饰基团的酞菁金属配合物及其制备方法
CN102755647A (zh) * 2012-07-23 2012-10-31 中国科学院福建物质结构研究所 五聚赖氨酸酞菁锌在制备杀菌药物中的应用
US10398315B2 (en) 2013-12-06 2019-09-03 Agency For Science, Technology And Research Method of imaging living tissue
CN103772397B (zh) * 2014-01-25 2016-02-24 福州大学 一类哌嗪修饰的酞菁配合物及其制备方法
CN105363031B (zh) * 2014-09-01 2019-04-02 北京贵千金医药科技有限公司 α-(8-喹啉氧基)单取代酞菁锌治疗银屑病的用途
EP3553062A1 (en) * 2018-04-09 2019-10-16 Chemical Intelligence Limited Antimicrobial and anticancer cationic phthalocyanine compounds
IL285978B2 (en) * 2019-03-06 2025-12-01 Molteni Therapeutics Srl Topical formulations containing phthalocyanine photosensitizers
CN112028901B (zh) * 2020-10-16 2021-06-01 福州大学 十六铵基修饰的酞菁及其制备方法与作为光动力药物的应用
WO2022113756A1 (ja) * 2020-11-24 2022-06-02 富士フイルム株式会社 着色組成物、硬化物、カラーフィルタ、固体撮像素子、画像表示装置、並びに、化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4961755A (en) * 1987-12-29 1990-10-09 Ciba-Geigy Corporation Coated active substances: dye coated with polyethylene oxide-propylene oxide or with ethoxylated stearyldi phenyloxyethyl diethylenetriamine
US5446141A (en) * 1988-04-01 1995-08-29 Mitsui Toatsu Chemicals, Incorporated Alkylphthalocyanine near-infrared absorbers and recording/display materials using the same
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
JP3129030B2 (ja) * 1993-06-04 2001-01-29 東洋インキ製造株式会社 銅フタロシアニン顔料組成物の製造方法
GB9317881D0 (en) * 1993-08-27 1993-10-13 Secr Defence Photosensitizers
JP3830993B2 (ja) * 1995-08-23 2006-10-11 株式会社興人 水溶性金属フタロシアニン誘導体を担持した消臭抗菌材

Also Published As

Publication number Publication date
ATE506057T1 (de) 2011-05-15
CY1111832T1 (el) 2015-10-07
EP0906758A1 (en) 1999-04-07
DE69842227D1 (de) 2011-06-01
CA2245066A1 (en) 1999-02-14
CA2245066C (en) 2009-10-20
ES2365383T3 (es) 2011-10-03
PT906758E (pt) 2011-07-29
ITMI971940A1 (it) 1999-02-14
IT1294325B1 (it) 1999-03-24
EP0906758B1 (en) 2011-04-20
US5965598A (en) 1999-10-12

Similar Documents

Publication Publication Date Title
DK0906758T3 (da) Zink-phthalocyaniner og tilsvarende konjugater, deres frembingelse og anvendelse i fotodynamisk terapi og som diagnostiske midler
IT1333697B (da)
EA200200616A1 (ru) Химические производные и их применение в качестве антителомеразного агента
DE60029944D1 (de) Polyamine und ihre therapeutische verwendung
MY121294A (en) Novel hexanoic acid derivatives.
BR0007527A (pt) Fenilfenantridinas com atividade inibitória depde-iv
DE60008354D1 (de) Substituierte Metallphthalocyaninen, ihre Herstellung und Verwendung
BR9916096A (pt) Derivados de bacterioclorofila substituìdos compaládio e utilização dos mesmos
BR0309499A (pt) Derivados de [1,4]diazocino[7,8,1-hi]indol como agentes antipsicóticos e antiobesidade
DK1381611T3 (da) Metalsubstituerede ikke-centrosymmetriske phthalocyaninanaloger, fremstilling heraf og anvendelse i fotodynamisk terapi samt in vivo diagnostik
PT882726E (pt) Carbazol-carboxamidas como agonistas 5-ht1f
GR3033350T3 (en) Use of Beta-aminopropionic acid derivatives as fungicides
BR0307400A (pt) Compostos de porfirina platina solúveis em água com alta seletividade de tumor e seu uso para o tratamento de doenças de tumor benigno e maligno
CY1106759T1 (el) Θεραπεια της δυσκινησιας
WO2003028628A3 (en) Photosensitizing carbamate derivatives
PT1267931E (pt) Derivados de rodamina para o diagnostico e tratamento fotodinamicos
DK0916670T3 (da) Pyrrolo[3,2-b]pyridiner og deres anvendelse som 5-HT1f-agonister
CA2298820A1 (en) The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives
AU2001292698A1 (en) Hexahydropyrazino `1'2' : 1, 6!- pyrido `3, 4-b! indole-1, 4-dione derivatives for the treatment of cardiovascular disorders and erectile disfunction
ATE466835T1 (de) Aliphatisch substituierte demethoxylierte hypocrelline und deren herstellung
BRPI0417140A (pt) derivados quinolina ácidos e seu uso na prevenção e/ou tratamento de patologias relacionadas com hiperglicemia
BR8906421A (pt) Processo para preparacao de monopersulfato de piridina-3-acido peroxicarboxilico
BR9912839A (pt) Derivados de piperazinomas e suas aplicações
ES2159087T3 (es) Oxindoles sustituidos con adamantilo como agentes farmaceuticos.