BR0309703A - Sistemas de análise de injeção sequencial automatizada para a determinação de nìveis de traços de endotoxina - Google Patents

Sistemas de análise de injeção sequencial automatizada para a determinação de nìveis de traços de endotoxina

Info

Publication number
BR0309703A
BR0309703A BR0309703-0A BR0309703A BR0309703A BR 0309703 A BR0309703 A BR 0309703A BR 0309703 A BR0309703 A BR 0309703A BR 0309703 A BR0309703 A BR 0309703A
Authority
BR
Brazil
Prior art keywords
fluid
endotoxin
fluids
light
determination
Prior art date
Application number
BR0309703-0A
Other languages
English (en)
Inventor
Purnendu Kumar Dasgupta
Ronald Norman Berzofsky
Matthew Richard Bonen
Original Assignee
Biowhittaker Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biowhittaker Technologies Inc filed Critical Biowhittaker Technologies Inc
Publication of BR0309703A publication Critical patent/BR0309703A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N2001/022—Devices for withdrawing samples sampling for security purposes, e.g. contraband, warfare agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00663—Quality control of consumables
    • G01N2035/00673—Quality control of consumables of reagents

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"SISTEMAS DE ANáLISE DE INJEçãO SEQuENCIAL AUTOMATIZADA PARA A DETERMINAçãO DE NìVEIS DE TRAçOS DE ENDOTOXINA". é descrito um sistema (10) e método usados para detectar a presença de endotoxina em uma amostra de fluido. o sistema (10) inclui uma bomba de liberação de fluido bidirecional (20) para introduzir, mover e misturar fluidos dentro do sistema (10) . O sistema (10) também inclui um componente de contenção de fluido (50) em comunicação fluídica com a bomba de liberação de fluido (20) . Fluidos, incluindo uma amostra de fluido de teste, reagente LAL e segmentos de fluido de substrato cromogênico, são aspirados para o componente de contenção de fluido (50) em resposta à operação da bomba de liberação de fluido (20). Depois de ser misturados, esses fluidos são entregues a uma parte de uma célula do detector (105) de um detector (100), onde uma luz proveniente de uma fonte de luz (150) é introduzida na célula do detector (105). Luz da célula do detector (105) é coletada e comparada com luz da fonte de luz (150) para determinar se endotoxina está presente na amostra de fluido. Depois que os fluidos misturados forem entregues na célula do detector (105), os fluidos de lavagem introduzidos limpam o sistema (10) . Ar é também introduzido no sistema (10) a fim de eliminar os fluidos de lavagem de dentro do sistema (10).
BR0309703-0A 2002-04-30 2003-04-30 Sistemas de análise de injeção sequencial automatizada para a determinação de nìveis de traços de endotoxina BR0309703A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37626802P 2002-04-30 2002-04-30
PCT/US2003/013519 WO2003093323A2 (en) 2002-04-30 2003-04-30 Automated sequential injection analysis systems for the determination of trace endotoxin levels

Publications (1)

Publication Number Publication Date
BR0309703A true BR0309703A (pt) 2005-02-09

Family

ID=29401324

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0309703-0A BR0309703A (pt) 2002-04-30 2003-04-30 Sistemas de análise de injeção sequencial automatizada para a determinação de nìveis de traços de endotoxina

Country Status (6)

Country Link
US (1) US20050244299A1 (pt)
EP (1) EP1499643A4 (pt)
JP (1) JP2005524075A (pt)
AU (1) AU2003225254A1 (pt)
BR (1) BR0309703A (pt)
WO (1) WO2003093323A2 (pt)

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WO2016183016A1 (en) 2015-05-08 2016-11-17 Flownamics Analytical Instruments, Inc. Method & apparatus for continuous automated perfusion system harvesting from in-situ filtration probe
US20170336427A1 (en) * 2016-05-20 2017-11-23 Sentinel Monitoring Systems, Inc. Online liquid autosampler and processing system
CN105929124A (zh) * 2016-06-12 2016-09-07 深圳市清时捷科技有限公司 一种在线水质分析仪器及其水质分析方法
JP6807051B2 (ja) * 2016-10-27 2021-01-06 大日本印刷株式会社 微生物夾雑物検出装置および微生物夾雑物検出方法
WO2019028191A1 (en) * 2017-08-01 2019-02-07 Amgen Inc. SYSTEMS AND METHODS FOR PERFORMING REAL-TIME GLYCAN ASSAY OF A SAMPLE
JP6982476B2 (ja) * 2017-11-28 2021-12-17 オルガノ株式会社 フローインジェクション分析方法及び装置
JP6982477B2 (ja) * 2017-11-28 2021-12-17 オルガノ株式会社 フローインジェクション分析方法及び装置
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Also Published As

Publication number Publication date
WO2003093323A3 (en) 2004-03-04
JP2005524075A (ja) 2005-08-11
AU2003225254A1 (en) 2003-11-17
WO2003093323A2 (en) 2003-11-13
EP1499643A4 (en) 2008-04-16
WO2003093323A9 (en) 2004-04-15
US20050244299A1 (en) 2005-11-03
EP1499643A2 (en) 2005-01-26

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010.