BR9307570A - Diéteres de catecol como inibidores seletivos de pdeiv - Google Patents

Diéteres de catecol como inibidores seletivos de pdeiv

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Publication number
BR9307570A
BR9307570A BR9307570A BR9307570A BR9307570A BR 9307570 A BR9307570 A BR 9307570A BR 9307570 A BR9307570 A BR 9307570A BR 9307570 A BR9307570 A BR 9307570A BR 9307570 A BR9307570 A BR 9307570A
Authority
BR
Brazil
Prior art keywords
compounds
relates
selective
pdeiv inhibitors
catechol
Prior art date
Application number
BR9307570A
Other languages
English (en)
Inventor
Allen J Duplantier
James F Eggler
Anthony Marfat
Hiroko Masamune
Original Assignee
Pfizer
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Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9307570A publication Critical patent/BR9307570A/pt

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
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    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
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    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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BR9307570A 1992-12-02 1993-10-29 Diéteres de catecol como inibidores seletivos de pdeiv BR9307570A (pt)

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FI935379A7 (fi) 1994-06-03
PT672031E (pt) 2003-06-30
JPH08501318A (ja) 1996-02-13
NZ257955A (en) 1996-05-28
AU5539694A (en) 1994-06-22
EP0672031A1 (en) 1995-09-20
ZA938978B (en) 1995-06-01
ATE234270T1 (de) 2003-03-15
CA2400368A1 (en) 1994-06-09
IL107758A (en) 1997-11-20
WO1994012461A1 (en) 1994-06-09
NO952178D0 (no) 1995-06-01
DE69332762T2 (de) 2003-08-14
CN1094028A (zh) 1994-10-26
DK0672031T3 (da) 2003-06-10
IL107758A0 (en) 1994-02-27
FI935379A0 (fi) 1993-12-01
KR950704228A (ko) 1995-11-17
AU673569B2 (en) 1996-11-14
DE69332762D1 (de) 2003-04-17
CZ141795A3 (en) 1995-11-15
ES2192192T3 (es) 2003-10-01
CA2150812A1 (en) 1994-06-09
CA2150812C (en) 2002-12-24
PL309257A1 (en) 1995-10-02
HU9303423D0 (en) 1994-04-28
NO952178L (no) 1995-08-01
RU95113454A (ru) 1997-06-10
HUT65928A (en) 1994-07-28
JP3100984B2 (ja) 2000-10-23
EP0672031B1 (en) 2003-03-12

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