BR9402912A - Fungo filamentoso, linhagem recombinagem outra que não um fungo filamentoso; método para obtenção de uma linhagem recombinante livre de gene marcador de seleção; e vetor. - Google Patents

Fungo filamentoso, linhagem recombinagem outra que não um fungo filamentoso; método para obtenção de uma linhagem recombinante livre de gene marcador de seleção; e vetor.

Info

Publication number
BR9402912A
BR9402912A BR9402912A BR9402912A BR9402912A BR 9402912 A BR9402912 A BR 9402912A BR 9402912 A BR9402912 A BR 9402912A BR 9402912 A BR9402912 A BR 9402912A BR 9402912 A BR9402912 A BR 9402912A
Authority
BR
Brazil
Prior art keywords
filamentous fungus
recombinant
selection marker
vector
obtaining
Prior art date
Application number
BR9402912A
Other languages
English (en)
Inventor
Gerardus Cornelis Maria Selten
Bart Willem Swinkels
Gorcom Robertus Franciscus Van
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of BR9402912A publication Critical patent/BR9402912A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR9402912A 1993-07-23 1994-07-22 Fungo filamentoso, linhagem recombinagem outra que não um fungo filamentoso; método para obtenção de uma linhagem recombinante livre de gene marcador de seleção; e vetor. BR9402912A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93202195 1993-07-23

Publications (1)

Publication Number Publication Date
BR9402912A true BR9402912A (pt) 1995-04-11

Family

ID=8214006

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9402912A BR9402912A (pt) 1993-07-23 1994-07-22 Fungo filamentoso, linhagem recombinagem outra que não um fungo filamentoso; método para obtenção de uma linhagem recombinante livre de gene marcador de seleção; e vetor.

Country Status (13)

Country Link
US (3) US5876988A (pt)
EP (2) EP0635574B1 (pt)
JP (2) JP3833725B2 (pt)
CN (1) CN100347301C (pt)
AT (1) ATE238425T1 (pt)
BR (1) BR9402912A (pt)
CA (1) CA2128589C (pt)
DE (1) DE69432543T2 (pt)
DK (1) DK0635574T3 (pt)
ES (1) ES2198410T3 (pt)
FI (2) FI114481B (pt)
IE (1) IE20030875A1 (pt)
NZ (2) NZ264065A (pt)

Families Citing this family (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY134684A (en) 1995-05-15 2007-12-31 Gist Brocades Bv Application of phospholipases in animal feed
AU714511B2 (en) 1995-06-23 2000-01-06 Dupont Nutrition Biosciences Aps A novel method to isolate mutants and to clone the complementing gene
ATE418614T1 (de) 1995-08-03 2009-01-15 Dsm Ip Assets Bv Amds-gen aus aspergillus niger für eine acetamidase kodierend
EP0814165B1 (en) * 1996-06-21 2003-04-09 Suntory Limited Method for constructing transformed yeast cells, that do not contain a selective marker gene
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
JP4531868B2 (ja) * 1997-04-11 2010-08-25 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 1を超える非リボソームrnaをコードしているドメインの染色体ゲノムに組込まれた少なくとも2コピーの所望遺伝子を含む、特にクルイベロミセスによる酵母細胞
EP0979294B1 (en) * 1997-04-11 2015-05-27 DSM IP Assets B.V. Gene conversion as a tool for the construction of recombinant industrial filamentous fungi
US6558937B1 (en) 1997-07-31 2003-05-06 Dsm N.V. Cellulose degrading enzymes of aspergillus
PL341760A1 (en) * 1997-12-22 2001-05-07 Dsm Nv Expression cloning in mildew fungi
EP1040197A1 (en) * 1997-12-22 2000-10-04 Unilever N.V. A process for site-directed integration of multiple copies of a gene in a mould
PL344863A1 (en) 1998-05-19 2001-11-19 Dsm Nv Improved in vivo
US6358705B1 (en) 1998-07-16 2002-03-19 Novo Nordisk A/S Method of making proteins in transformed yeast cells
HUP0102697A3 (en) * 1998-07-16 2003-09-29 Novo Nordisk As Method of making proteins in transformed yeast cells
US7220542B2 (en) 2000-07-17 2007-05-22 Van Den Brink Johannes Maarten Expression cloning in filamentous fungi
US6750379B2 (en) * 2000-03-09 2004-06-15 Dekalb Genetics Corporation Homologous recombination-mediated transgene alterations in plants
CZ2003798A3 (cs) 2000-09-21 2003-08-13 Dsm N. V. Polypeptid s aktivitou xylanázy, sekvence nukleové kyseliny kódující polypeptid, způsob přípravy a použití polypeptidu
ATE418616T2 (de) 2002-01-23 2009-01-15 Royal Nedalco B V Fermentation von pentosezuckern
US7517671B2 (en) * 2002-02-28 2009-04-14 New England Biolabs, Inc. Methods and compositions for concentrating secreted recombinant protein
TWI328612B (en) 2002-07-25 2010-08-11 Dsm Ip Assets Bv Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12
WO2004048580A1 (en) * 2002-11-28 2004-06-10 Universiteit Leiden A method for marker-less integration of a sequence of interest into the genome of a cell
JP2006528970A (ja) 2003-05-28 2006-12-28 デーエスエム アイピー アセッツ ベー. ヴェー. セフェム化合物
CN1298213C (zh) * 2003-09-10 2007-02-07 王海波 一种通过分割处理获得无选择标记转基因植物的方法
EP1673380A2 (en) * 2003-10-14 2006-06-28 DSM IP Assets B.V. Method for preparing a modified host cell
WO2005095624A2 (en) 2004-04-02 2005-10-13 Dsm Ip Assets B.V. Filamentous fungal mutants with improved homologous recombination efficiency
JP4783359B2 (ja) 2004-04-16 2011-09-28 ディーエスエム アイピー アセッツ ビー.ブイ. 真菌細胞において遺伝子を発現させるための真菌プロモーター
EP1799821A2 (en) * 2004-10-15 2007-06-27 DSMIP Assets B.V. Homologous amds genes as selectable marker
US20090017061A1 (en) 2005-01-18 2009-01-15 Bernard Jan Appelmelk Mycobacteria with Mannose Cap-Deficient Lipoarabinomannan
AU2006207463B2 (en) 2005-01-24 2011-03-17 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
EP2458008A1 (en) 2005-11-29 2012-05-30 DSM IP Assets B.V. DNA binding site of a transcriptional activator useful in gene expression
BRPI0619091A2 (pt) 2005-12-01 2011-09-13 Dsm Ip Assests Bv novos genes úteis para a produção industrial de ácido cìtrico
ES2534282T3 (es) 2006-06-29 2015-04-21 Dsm Ip Assets B.V. Un método para lograr la expresión polipeptídica mejorada
EP2511372A1 (en) 2006-11-02 2012-10-17 DSM IP Assets B.V. Improved production of secreted proteins by filamentous fungi
US20100112638A1 (en) 2007-02-15 2010-05-06 Cornelis Maria Jacobus Sagt Recombinant host cell for the production of a compound of interest
DK2126100T3 (da) 2007-03-21 2013-01-14 Dsm Ip Assets Bv Forbedret fremgangsmåde til homolog rekombination
US8735112B2 (en) 2007-11-20 2014-05-27 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
WO2009065778A1 (en) 2007-11-20 2009-05-28 Dsm Ip Assets B.V. Succinic acid production in a eukaryotic cell
WO2009065777A1 (en) 2007-11-20 2009-05-28 Dsm Ip Assets B.V. Dicarboxylic acid production in a filamentous fungus
MX2010006679A (es) 2007-12-17 2010-11-30 Univ Amsterdam Reduccion de co2 inducida con luz para compuestos orgánicos que sirven como combustibles o como semiproductos industriales por un autotrofo que contiene un casete genico fermentador.
FR2927089B1 (fr) 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
EP2116136A1 (en) 2008-05-08 2009-11-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Novel phytases
CA2729626C (fr) * 2008-07-11 2017-12-12 Jean-Marc Nicaud Nouvelles souches de levure mutantes capables d'accumuler une grande quantite de lipides
CA2732104A1 (en) * 2008-07-29 2010-02-04 Danisco Us Inc. Increased production of aspartic proteases in filamentous fungal cells
CN102131921A (zh) 2008-08-05 2011-07-20 帝斯曼知识产权资产管理有限公司 生产己二酰基-7-adca的菌株
WO2010102976A1 (en) 2009-03-10 2010-09-16 Dsm Ip Assets B.V. Pregastric esterase and derivatives thereof
CN102741421B (zh) 2009-03-10 2015-03-25 帝斯曼知识产权资产管理有限公司 用于提高多肽产率的方法
US8735100B2 (en) 2009-03-17 2014-05-27 Nederlandse Organisatie Voor Toegepast -Natuurwetenschappelijk Onderzoek Tno Cellulose and ligno-cellulose active proteins
EP2419518A1 (en) 2009-04-15 2012-02-22 DSM IP Assets B.V. Dicarboxylic acid production process
EP2421986A1 (en) 2009-04-22 2012-02-29 DSM IP Assets B.V. Process for the production of a recombinant polypeptide of interest
BRPI1015536A2 (pt) 2009-04-24 2019-07-02 Dsm Ip Assets Bv polipeptídeo de degradação de carboidratos e usos do mesmo
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
EP3293264A1 (en) 2009-07-22 2018-03-14 DSM IP Assets B.V. Improved host cell for the production of a compound of interest
DK2491120T3 (en) 2009-10-22 2016-03-21 Basf Se Synthetic phytasevarianter
CA2779796A1 (en) * 2009-11-04 2011-05-12 Dsm Ip Assets B.V. Talaromyces transformants
CA2789176A1 (en) 2010-02-04 2011-08-11 Dsm Ip Assets B.V. Process for preparing filamentous fungal strains having a sexual cycle and a process for preparing sexually crossed filamentous fungal strains
US9133448B2 (en) 2010-02-11 2015-09-15 Dsm Ip Assets B.V. Polypeptide having cellobiohydrolase activity and uses thereof
EA201201125A1 (ru) 2010-02-11 2013-03-29 ДСМ АйПи АССЕТС Б.В. Клетка-хозяин, способная продуцировать ферменты, пригодные для деградации лигноцеллюлозного материала
JP2013524797A (ja) 2010-04-21 2013-06-20 ディーエスエム アイピー アセッツ ビー.ブイ. アラビノースを転化できる細胞を製造する方法
EP2388331A1 (en) 2010-05-21 2011-11-23 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Constitutive promoter
CA2803513A1 (en) 2010-06-29 2012-01-05 Margot Elisabeth Francoise Schooneveld-Bergmans Polypeptide having acetyl xylan esterase activity and uses thereof
DK2588494T3 (en) 2010-06-29 2018-06-14 Dsm Ip Assets Bv POLYPEPTIDE WITH BETA-GLUCOSIDASE ACTIVITY AND APPLICATIONS THEREOF
CA2802128A1 (en) 2010-06-29 2012-01-05 Margot Elisabeth Francoise Schooneveld-Bergmans Polypeptide having beta-glucosidase activity and uses thereof
WO2012000891A1 (en) 2010-06-29 2012-01-05 Dsm Ip Assets B.V. Polypeptide having carbohydrate degrading activity and uses thereof
BR112012033404B1 (pt) 2010-06-29 2021-05-18 Dsm Ip Assets B.V. célula recombinante, método para a preparação de um polipeptídeo, composição, método para o tratamento de um substrato que compreende material de carboidrato e uso de um polipeptídeo
US9175050B2 (en) 2010-06-29 2015-11-03 Dsm Ip Assets B.V. Polypeptide having swollenin activity and uses thereof
CA2803222A1 (en) 2010-07-01 2012-01-05 Dsm Ip Assets B.V. A method for the production of a compound of interest
JP5961886B2 (ja) 2010-10-13 2016-08-03 ディーエスエム アイピー アセッツ ビー.ブイ. ペントースおよびグルコース発酵酵母細胞
CN103596970A (zh) 2011-03-11 2014-02-19 帝斯曼知识产权资产管理有限公司 载体-宿主系统
WO2012143861A1 (en) 2011-04-21 2012-10-26 Basf Se Synthetic phytase variants
WO2012143513A2 (en) 2011-04-22 2012-10-26 Dsm Ip Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose
EP2554668A1 (en) 2011-08-04 2013-02-06 DSM IP Assets B.V. A pentose sugar fermenting cell
AR087423A1 (es) 2011-08-04 2014-03-19 Dsm Ip Assets Bv Celula capaz de fermentar azucares pentosas
MX355028B (es) 2012-01-23 2018-03-28 Dsm Ip Assets Bv Produccion de diterpeno.
WO2013189878A1 (en) 2012-06-19 2013-12-27 Dsm Ip Assets B.V. Promoters for expressing a gene in a cell
MX357482B (es) 2012-07-19 2018-07-11 Dsm Ip Assets Bv Cepa deficiente en agse.
ES2717682T3 (es) 2012-10-16 2019-06-24 Dsm Ip Assets Bv Células con conversión mejorada de pentosas
WO2014096436A1 (en) * 2012-12-21 2014-06-26 Estibio Aps Marker-free genetically-engineered double mutants of thermoanaerobacter
CN105073986A (zh) 2013-02-04 2015-11-18 帝斯曼知识产权资产管理有限公司 碳水化合物降解多肽及其用途
EP2772545A1 (en) 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Starch active proteins
WO2014142647A1 (en) 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
WO2014161988A1 (en) 2013-04-05 2014-10-09 Université Du Luxembourg Biotechnological production of itaconic acid
BR112015027609A2 (pt) 2013-05-02 2017-12-05 Dutch Dna Biotech B V uso de uma proteína, vetor para transformação de um microrganismo, organismo transgênico, e, métodos para produção de um ácido cítrico, de um ácido itacônico e de um derivado de ácido cítrico
BR112015029580A2 (pt) 2013-05-31 2017-09-19 Dsm Ip Assets Bv Microrganismo recombinante, processo para a preparação de um diterpeno ou diterpeno glicosilado, diterpeno ou diterpeno glicosilado, gêneros alimentícios, alimentos para animais ou bebidas e método para converter um primeiro diterpeno glicosilado em um segundo diterpeno glicosilado
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
BR112016000745B1 (pt) 2013-07-15 2021-01-05 Dsm Ip Assets B.V. processo para a preparação de rebaudiosídeo m
DK3027632T3 (da) 2013-07-31 2019-06-17 Dsm Ip Assets Bv Indvinding af steviolglycosider fra et fermenteringsmedium
WO2015082488A1 (en) 2013-12-02 2015-06-11 Dsm Ip Assets B.V. Ice structuring protein
WO2016012429A1 (en) 2014-07-24 2016-01-28 Dsm Ip Assets B.V. Yeast cell with improved pentose transport
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
US11396665B2 (en) 2015-01-06 2022-07-26 Dsm Ip Assets B.V. CRISPR-CAS system for a filamentous fungal host cell
CN108064287A (zh) 2015-01-06 2018-05-22 帝斯曼知识产权资产管理有限公司 用于解脂酵母宿主细胞的crispr-cas系统
EP3242949B1 (en) 2015-01-06 2021-11-03 DSM IP Assets B.V. A crispr-cas system for a yeast host cell
CN107250163A (zh) 2015-02-06 2017-10-13 嘉吉公司 修饰的葡糖淀粉酶和具有增强的生物产物产生的酵母菌株
EP3259361A1 (en) 2015-02-16 2017-12-27 DSM IP Assets B.V. Process for producing itaconic acid under anaerobic conditions
EP3271457B1 (en) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransferases
US20180057850A1 (en) 2015-03-23 2018-03-01 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
WO2016160584A1 (en) 2015-03-27 2016-10-06 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
CN107666834B (zh) 2015-04-03 2021-08-24 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷
CA2980649A1 (en) 2015-04-21 2016-10-27 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthase
WO2016188813A1 (en) 2015-05-22 2016-12-01 Dsm Ip Assets B.V. Acetate consuming yeast cell
WO2016193292A1 (en) 2015-06-02 2016-12-08 Dsm Ip Assets B.V. Use of ice structuring protein afp19 expressed in filamentous fungal strains for preparing food
CA2991651A1 (en) 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Steviol glycoside composition
EP3332004B1 (en) 2015-08-05 2025-01-22 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
US20180230505A1 (en) 2015-08-13 2018-08-16 Dsm Ip Assets B.V. Steviol glycoside transport
KR20180053684A (ko) 2015-09-21 2018-05-23 푸락 바이오켐 비.브이. Fdca의 진균 제조
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
BR112018006724A2 (pt) 2015-10-05 2018-10-09 Dsm Ip Assets Bv ácido caurenoico hidroxilases
PL3359655T3 (pl) * 2015-10-06 2020-05-18 Dsm Ip Assets B.V. Komórka eukariotyczna ze zwiększonym wytwarzaniem produktu fermentacji
BR112018010384A2 (pt) 2015-11-24 2018-12-04 Cargill Inc levedura geneticamente modificada e processo para fabricar um produto de fermentação
MX391717B (es) 2015-12-02 2025-03-21 Basf Se Metodo para producir proteinas en hongos filamentosos con accion clr2 reducida.
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CA3007635A1 (en) 2015-12-07 2017-06-15 Zymergen Inc. Promoters from corynebacterium glutamicum
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
CA3007840C (en) 2015-12-07 2020-09-15 Zymergen Inc. Microbial strain improvement by a htp genomic engineering platform
CN108431229A (zh) 2015-12-17 2018-08-21 嘉吉公司 糖转运蛋白修饰的酵母菌株和用于生物制品生产的方法
CA3009871A1 (en) 2015-12-30 2017-07-06 Dsm Ip Assets B.V. Partial enzymatic hydrolysis of triacylglycerols
JP2019500041A (ja) 2015-12-30 2019-01-10 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. トリアシルグリセロールの部分的酵素加水分解
WO2017167847A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Production of milk with low lactose content
EP3435771A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
EP3435772A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
US10689670B2 (en) 2016-06-14 2020-06-23 Dsm Ip Assets B.V. Recombinant yeast cell
JP2019519242A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド 細菌ヘモグロビンライブラリーを生成するための方法およびその使用
WO2018005793A1 (en) 2016-06-30 2018-01-04 Zymergen Inc. Methods for generating a glucose permease library and uses thereof
CA3030605A1 (en) 2016-07-13 2018-01-18 Dsm Ip Assets B.V. Malate dehyrogenases
WO2018019948A1 (en) 2016-07-29 2018-02-01 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
CN109661403A (zh) 2016-08-05 2019-04-19 嘉吉公司 前导序列修饰的葡糖淀粉酶多肽和具有增强的生物产物产生的工程化的酵母菌株
MY202890A (en) 2016-08-09 2024-05-28 Dsm Ip Assets Bv Crystallization of steviol glycosides
EP3497110A1 (en) 2016-08-09 2019-06-19 DSM IP Assets B.V. Crystallization of steviol glycosides
WO2018037123A1 (en) 2016-08-26 2018-03-01 Lesaffre Et Compagnie Improved production of itaconic acid
WO2018073107A1 (en) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
CN109890961B (zh) 2016-10-27 2024-03-08 帝斯曼知识产权资产管理有限公司 香叶基香叶基焦磷酸酯合酶
CA3045722A1 (en) 2016-12-08 2018-06-14 Dsm Ip Assets B.V. Kaurenoic acid hydroxylases
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
US10918113B2 (en) 2016-12-21 2021-02-16 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114940A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
JP2020503037A (ja) * 2016-12-30 2020-01-30 ザイマージェン インコーポレイテッド 遺伝子操作および株精製のための自動化ステップを使用する真菌産生株を構築する方法
CN110431224A (zh) 2017-03-13 2019-11-08 帝斯曼知识产权资产管理有限公司 锌双核簇转录调控因子缺陷型菌株
EP3378931A1 (en) 2017-03-21 2018-09-26 Purac Biochem B.V. Fdca-decarboxylating monooxygenase-deficient host cells for producing fdca
EP3635111A1 (en) 2017-06-06 2020-04-15 Zymergen, Inc. High throughput transposon mutagenesis
KR20200026878A (ko) 2017-06-06 2020-03-11 지머젠 인코포레이티드 균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
WO2018228836A1 (en) 2017-06-13 2018-12-20 Dsm Ip Assets B.V. Recombinant yeast cell
EP3645714B1 (en) 2017-06-27 2022-08-31 DSM IP Assets B.V. Udp-glycosyltransferases
EP3688177A1 (en) 2017-09-26 2020-08-05 DSM IP Assets B.V. Acetic acid consuming strain
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus
EP3759209A4 (en) 2018-02-28 2022-02-09 Cargill, Incorporated GLUCOAMYLASE MANIPULATED YEAST AND FERMENTATION PROCESSES
CN112424326A (zh) 2018-05-07 2021-02-26 帝斯曼知识产权资产管理有限公司 用于酶促油脱胶的方法
EP3810750A4 (en) 2018-06-06 2022-03-23 Zymergen, Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
US12195769B2 (en) 2018-06-19 2025-01-14 Dsm Ip Assets B.V. Lipolytic enzyme variants
US20220389458A1 (en) 2019-11-04 2022-12-08 Dsm Ip Assets B.V. Low volume transfection
US20230212634A1 (en) 2020-01-14 2023-07-06 The Protein Brewery B.V. Expression of Ovalbumin and its Natural Variants
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
US20250290081A1 (en) 2020-10-22 2025-09-18 Dsm Ip Assets B.V. Microorganisms for diterpene production
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
EP4359426A2 (en) 2021-06-24 2024-05-01 Fonterra Co-Operative Group Limited Recombinant beta-lactoglobulin
WO2023285297A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
EP4370688A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
MX2024000511A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
EP4370691A1 (en) 2021-07-12 2024-05-22 Danisco US Inc. Recombinant yeast cell
EP4370690A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
MX2024000509A (es) 2021-07-12 2024-03-15 Danisco Us Inc Celula de levadura recombinante.
MX2024005281A (es) 2021-11-04 2024-05-17 Danisco Us Inc Celula de levadura recombinante.
EP4426848A1 (en) 2021-11-04 2024-09-11 Danisco Us Inc Process for the production of ethanol and recombinant yeast cell
CN118234857A (zh) 2021-11-04 2024-06-21 丹尼斯科美国公司 变体多肽和重组酵母细胞
TW202325853A (zh) 2021-11-09 2023-07-01 美商安進公司 治療性蛋白之生產
US20250304938A1 (en) 2022-05-16 2025-10-02 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation
CN121127603A (zh) 2023-04-20 2025-12-12 帝斯曼知识产权资产管理有限公司 用于产生罗汉果苷的菌株和方法
WO2025012325A1 (en) 2023-07-11 2025-01-16 Dsm Ip Assets B.V. Protein arginine deiminase
WO2025144795A1 (en) 2023-12-28 2025-07-03 Dsm Ip Assets B.V. Cells and methods for the production of glycosylated compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422267A (en) * 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
EP0625577A1 (en) * 1985-08-29 1994-11-23 Genencor International, Inc. Heterologous polypeptides expressed in filamentous fungi, processes for their preparation, and vectors for their preparation
US5298405A (en) * 1986-04-30 1994-03-29 Alko Limited Enzyme preparations with recombinantly-altered cellulose profiles and methods for their production
US5079145A (en) * 1988-10-21 1992-01-07 Synergen Associates, Inc. Process for preparing microorganisms used for making phenyl acetyl carlinol (pac)
GB8904762D0 (en) * 1989-03-02 1989-04-12 Glaxo Group Ltd Biological process
US5695976A (en) * 1989-12-18 1997-12-09 Novo Nordisk A/S Stable integration of DNA in bacterial genomes
US5498830A (en) * 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
EP0498137A1 (en) * 1991-02-06 1992-08-12 Novo Nordisk A/S Novel expression systems
WO1993001283A1 (en) * 1991-07-08 1993-01-21 The United States Of America As Represented By The Secretary Of Agriculture Selection-gene-free transgenic plants
EP0565172A1 (en) * 1992-04-10 1993-10-13 Quest International B.V. Cloning and expression of DNA encoding a ripening form of a polypeptide having sulfhydryl oxidase activity
CA2096289A1 (en) * 1992-05-15 1993-11-16 Wouter Musters Cloning and expression of dna encoding a ripening form of a polypeptide having rhamnogalacturonase activity
US6291205B1 (en) * 1992-06-12 2001-09-18 Merck & Co., Inc. Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae
US6110713A (en) * 1993-03-23 2000-08-29 Regents Of The University Of Minnesota Production of glutamic acid and lysine using auxotrophic mutants of Bacillus methanolicus

Also Published As

Publication number Publication date
CA2128589A1 (en) 1995-01-24
NZ264065A (en) 1998-06-26
FI943485A0 (fi) 1994-07-22
ATE238425T1 (de) 2003-05-15
CN1098743A (zh) 1995-02-15
EP1321523A2 (en) 2003-06-25
IE20030875A1 (en) 2004-01-14
DE69432543T2 (de) 2003-12-24
AU6862894A (en) 1995-02-02
EP1321523A3 (en) 2004-03-03
FI943485L (fi) 1995-01-24
ES2198410T3 (es) 2004-02-01
US6063614A (en) 2000-05-16
CN100347301C (zh) 2007-11-07
DE69432543D1 (de) 2003-05-28
JP2005296019A (ja) 2005-10-27
CA2128589C (en) 2005-10-11
FI117388B (fi) 2006-09-29
DK0635574T3 (da) 2003-08-11
EP0635574A1 (en) 1995-01-25
US5876988A (en) 1999-03-02
EP0635574B1 (en) 2003-04-23
AU690909B2 (en) 1998-05-07
US6955909B1 (en) 2005-10-18
IE940591A1 (en) 1995-01-25
JP3833725B2 (ja) 2006-10-18
JPH07147971A (ja) 1995-06-13
FI114481B (fi) 2004-10-29
NZ299139A (en) 1998-06-26
FI20041124L (fi) 2004-08-27

Similar Documents

Publication Publication Date Title
EP1321523A3 (en) Selection marker gene free recombinant strains; a method for obtaining them and the use of these strains
EP1092771A3 (en) Tetracycline-regulated transcriptional modulators
AU1383695A (en) An enzyme feed additive and animal feed including it
DE69636866D1 (en) Reverse "two-hybrid"-systeme
EP1156108A3 (en) Use of exo-sample nucleotides in gene cloning
WO1998046772A3 (en) Gene conversion as a tool for the construction of recombinant industrial filamentous fungi
EP0874055A3 (en) Method for the protection of plants against pathogens
PH12022553337A1 (en) Heterozygous cenh3 monocots and methods of use thereof for haploid induction and simultaneous genome editing
RO117190B1 (ro) Construct de acid nucleic şi metodă pentru identificarea expresiei unei gene heteroloage, într-o plantă
Turner et al. Diversity of repC plasmid-replication sequences in Rhizobium leguminosarum
ES8605038A1 (es) Un procedimiento para la transformacion de yarrowia lipolytica
JPS57206700A (en) Structural gene in transformed microbial host cell and structural gene coding various allele and maturity form of preprothaumatin recombined cloning vehicle
Itaya Bacillus subtilis 168 as a unique platform enabling synthesis and dissemination of genomes
EP0841402A3 (en) High capacity binary shuttle vector
Watanabe et al. Glutathione production by Escherichia coli cells with hybrid plasmid containing tandemly polymerized genes for glutathione synthetase
ATE113655T1 (de) Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten.
ATE72837T1 (de) Vielfach amplifizierbare vektoren fuer hohe expression exogener dns.
Rao et al. Rhizobium meliloti lacking mosA synthesizes the rhizopine scyllo-inosamine in place of 3-O-methyl-scyllo-inosamine
Turi et al. Cytochrome P450 lanosterol 14α‐demethylase (ERG11) and manganese superoxide dismutase (SOD1) are adjacent genes in Saccharomyces cerevisiae
DK391185D0 (da) Rekombinant saccharomyces
AU1671199A (en) Nucleic acids involved in the responder phenotype and applications thereo
Raab et al. Cell free synthesis of bacteriophage lambda replication proteins
Raabe et al. The H-NS-like protein HvrA modulates expression of nitrogen fixation genes in the phototrophic purple bacterium Rhodobacter capsulatus by binding to selected nif promoters
JPH0322157B2 (pt)
AU2162101A (en) Vectors and method for producing recombinant proteins in fungi

Legal Events

Date Code Title Description
EE Request for examination
PC Transfer

Free format text: DSM N.V. (NL)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]