BR9602394A - Guanididas de ácido alquenilcarboxílico processo para a sua preparação seus usos método para o tratamento de arritmias bem como medicamento - Google Patents

Guanididas de ácido alquenilcarboxílico processo para a sua preparação seus usos método para o tratamento de arritmias bem como medicamento

Info

Publication number
BR9602394A
BR9602394A BR9602394A BR9602394A BR9602394A BR 9602394 A BR9602394 A BR 9602394A BR 9602394 A BR9602394 A BR 9602394A BR 9602394 A BR9602394 A BR 9602394A BR 9602394 A BR9602394 A BR 9602394A
Authority
BR
Brazil
Prior art keywords
arrhythmias
medicine
preparation
treatment
well
Prior art date
Application number
BR9602394A
Other languages
English (en)
Inventor
Heinz-Werner Kleemann
Andreas Weichert
Hans Jochen Lang
Jan-Robert Schwark
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9602394A publication Critical patent/BR9602394A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/10—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9602394A 1995-05-22 1996-05-21 Guanididas de ácido alquenilcarboxílico processo para a sua preparação seus usos método para o tratamento de arritmias bem como medicamento BR9602394A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19518796A DE19518796A1 (de) 1995-05-22 1995-05-22 Fluorphenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
BR9602394A true BR9602394A (pt) 1998-10-06

Family

ID=7762597

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9602394A BR9602394A (pt) 1995-05-22 1996-05-21 Guanididas de ácido alquenilcarboxílico processo para a sua preparação seus usos método para o tratamento de arritmias bem como medicamento

Country Status (29)

Country Link
US (2) US20010020042A1 (pt)
EP (1) EP0744397B1 (pt)
JP (1) JP3924018B2 (pt)
KR (1) KR960041152A (pt)
CN (1) CN1063437C (pt)
AR (1) AR002744A1 (pt)
AT (1) ATE192431T1 (pt)
AU (1) AU701493B2 (pt)
BR (1) BR9602394A (pt)
CA (1) CA2177007C (pt)
CZ (1) CZ291622B6 (pt)
DE (2) DE19518796A1 (pt)
DK (1) DK0744397T3 (pt)
ES (1) ES2147629T3 (pt)
GR (1) GR3033416T3 (pt)
HR (1) HRP960230B1 (pt)
HU (1) HUP9601358A3 (pt)
IL (1) IL118327A (pt)
MY (1) MY113803A (pt)
NO (1) NO305552B1 (pt)
NZ (1) NZ286622A (pt)
PL (1) PL183431B1 (pt)
PT (1) PT744397E (pt)
RU (1) RU2164913C2 (pt)
SI (1) SI0744397T1 (pt)
SK (1) SK281527B6 (pt)
TR (1) TR199600421A2 (pt)
TW (1) TW415936B (pt)
ZA (1) ZA964035B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011059A (en) * 1997-12-24 2000-01-04 Bristol-Myers Squibb Company Acyl guanidine sodium/proton exchange inhibitors and method
US6160134A (en) * 1997-12-24 2000-12-12 Bristol-Myers Squibb Co. Process for preparing chiral cyclopropane carboxylic acids and acyl guanidines
AU4360200A (en) 1999-04-23 2000-11-10 Bristol-Myers Squibb Company Bicyclic acyl guanidine sodium/proton exchange inhibitors and method
DE10046993A1 (de) * 2000-09-22 2002-04-11 Aventis Pharma Gmbh Substituierte Zimtsäureguanidide, Verfahren zur ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament
EP2617709B8 (en) * 2003-06-26 2022-12-21 Biotron Limited Guanidine derivatives as antiviral agents
NZ596107A (en) * 2005-06-24 2013-09-27 Biotron Ltd Antiviral compounds and methods
AU2013205388B2 (en) * 2005-06-24 2016-05-05 Biotron Limited Antiviral compounds and methods
SI2384318T1 (en) 2008-12-31 2018-03-30 Ardelyx, Inc. MEASURES AND PROCEDURES FOR THE INHIBITION OF ANTIPORT INHIBITED BY NHE IN THE TREATMENT OF DISEASES RELATED TO STRENGTH OF FLAMMABILITY OR TRADEMARITY WITH SOLO, AND THE EMISSION OF GASTROINTESTINAL TREATMENT
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
MX366293B (es) 2012-08-21 2019-07-04 Ardelyx Inc Compuestos y metodos para inhibir al antipuerto mediado por nhe en el tratamiento de trastornos asociados con la retencion de fluidos o la sobrecarga de sal y trastornos del tracto gastrointestinal.
LT2983667T (lt) 2013-04-12 2019-07-10 Ardelyx, Inc. Nhe3 rišantys junginiai ir fosfato pernešimo slopinimo būdai
EA201991676A1 (ru) 2017-01-09 2020-01-30 Арделикс, Инк. Ингибиторы nhe-опосредованного антипорта
CA3049678A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds useful for treating gastrointestinal tract disorders
CN118440135A (zh) 2017-08-04 2024-08-06 阿德利克斯股份有限公司 用于治疗高钾血症的甘草次酸衍生物
KR20260004570A (ko) 2019-02-07 2026-01-08 알데릭스, 인코포레이티드 고칼륨혈증 치료에 사용하기 위한 글리시레틴산 유도체
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN121159798B (zh) * 2025-11-21 2026-02-17 北京大学口腔医学院 一种用于高效防治龋病的共价有机框架及其制备方法和应用

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US564937A (en) * 1896-07-28 Culm-loader
US2734904A (en) * 1956-02-14 Xcxnhxc-nh
US2743904A (en) 1950-11-07 1956-05-01 Loren F Scott Excavating apparatus
US3571861A (en) * 1968-11-26 1971-03-23 Famco Inc Bag closure means
US3612475A (en) * 1969-04-02 1971-10-12 Amp Inc Flexible tube closure
US3713622A (en) * 1971-02-26 1973-01-30 Amp Inc Closure device for flexible tubing
US3874042A (en) * 1973-01-22 1975-04-01 Biospectrum Inc Clamp for thin walled tubing
US3857396A (en) * 1973-08-22 1974-12-31 C Hardwick Suture clamp
US4547202A (en) * 1982-02-02 1985-10-15 Atlantic Richfield Company Hydrocarbon oils with improved pour points
US4454875A (en) * 1982-04-15 1984-06-19 Techmedica, Inc. Osteal medical staple
US4548201A (en) * 1982-04-20 1985-10-22 Inbae Yoon Elastic ligating ring clip
US4544670A (en) 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
US4534350A (en) * 1983-06-20 1985-08-13 Ethicon, Inc. Two-piece tissue fastener with compressible leg staple and retaining receiver
US4612923A (en) * 1983-12-01 1986-09-23 Ethicon, Inc. Glass-filled, absorbable surgical devices
US4646741A (en) * 1984-11-09 1987-03-03 Ethicon, Inc. Surgical fastener made from polymeric blends
US4955913A (en) * 1985-03-28 1990-09-11 Robinson Walter C Surgical tie
US4889119A (en) * 1985-07-17 1989-12-26 Ethicon, Inc. Surgical fastener made from glycolide-rich polymer blends
US5366459A (en) * 1987-05-14 1994-11-22 Inbae Yoon Surgical clip and clip application procedures
US4960420A (en) * 1988-08-23 1990-10-02 Marlowe Goble E Channel ligament clamp and system
US4932962A (en) * 1989-05-16 1990-06-12 Inbae Yoon Suture devices particularly useful in endoscopic surgery and methods of suturing
US4955959A (en) * 1989-05-26 1990-09-11 United States Surgical Corporation Locking mechanism for a surgical fastening apparatus
US4997433A (en) * 1990-01-16 1991-03-05 Marlowe Goble E Endosteal fixation stud and system
US5013316A (en) * 1990-03-26 1991-05-07 Marlowe Goble E Soft tissue anchor system
US5078731A (en) * 1990-06-05 1992-01-07 Hayhurst John O Suture clip
US5152034A (en) * 1990-10-19 1992-10-06 Konings Frederikus J J Click-clip
US5425489A (en) * 1990-12-20 1995-06-20 United States Surgical Corporation Fascia clip and instrument
US6102921A (en) * 1990-12-21 2000-08-15 University Of New Mexico Nerve anastomosis sling and method
US5203864A (en) * 1991-04-05 1993-04-20 Phillips Edward H Surgical fastener system
US5217472A (en) * 1991-05-07 1993-06-08 United States Surgical Corporation Surgical fastening device
US5257713A (en) * 1991-05-07 1993-11-02 United States Surgical Corporation Surgical fastening device
GB9111972D0 (en) * 1991-06-04 1991-07-24 Clinical Product Dev Ltd Medical/surgical devices
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
US5356064A (en) * 1991-10-18 1994-10-18 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5289963A (en) * 1991-10-18 1994-03-01 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5497933A (en) * 1991-10-18 1996-03-12 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5333624A (en) * 1992-02-24 1994-08-02 United States Surgical Corporation Surgical attaching apparatus
US5171251A (en) * 1992-03-02 1992-12-15 Ethicon, Inc. Surgical clip having hole therein and method of anchoring suture
US5425737A (en) * 1992-04-08 1995-06-20 American Cyanamid Co. Surgical purse string suturing instrument and method
US6312442B1 (en) * 1992-06-02 2001-11-06 General Surgical Innovations, Inc. Method for developing an anatomic space for laparoscopic hernia repair
CA2104345A1 (en) * 1992-09-02 1994-03-03 David T. Green Surgical clamp apparatus
US5362294A (en) * 1992-09-25 1994-11-08 Seitzinger Michael R Sling for positioning internal organ during laparoscopic surgery and method of use
US5282832A (en) * 1992-10-09 1994-02-01 United States Surgical Corporation Suture clip
US5464416A (en) * 1992-11-10 1995-11-07 Ethicon, Inc. Ligating clip
US5328077A (en) * 1992-11-19 1994-07-12 Lou Ek Seng Method and apparatus for treating female urinary incontinence
US5649939A (en) * 1992-12-08 1997-07-22 Reddick; Eddie J. Laparoscopic suture introducer
DK0612723T3 (da) * 1993-02-20 1998-03-30 Hoechst Ag Substituerede benzoylguanidiner, fremgangsmåde til fremstilling, deres anvendelse som lægemiddel, som inhibitor af den cellulære Na+/H+-udbytning eller som diagnostikum samt lægemiddel med indhold deraf
US5354292A (en) * 1993-03-02 1994-10-11 Braeuer Harry L Surgical mesh introduce with bone screw applicator for the repair of an inguinal hernia
US5474543A (en) * 1993-05-17 1995-12-12 Mckay; Hunter A. Single needle apparatus and method for performing retropublic urethropexy
CA2124651C (en) * 1993-08-20 2004-09-28 David T. Green Apparatus and method for applying and adjusting an anchoring device
US5507754A (en) * 1993-08-20 1996-04-16 United States Surgical Corporation Apparatus and method for applying and adjusting an anchoring device
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US5542594A (en) * 1993-10-06 1996-08-06 United States Surgical Corporation Surgical stapling apparatus with biocompatible surgical fabric
US5618290A (en) * 1993-10-19 1997-04-08 W.L. Gore & Associates, Inc. Endoscopic suture passer and method
US5776147A (en) * 1993-10-20 1998-07-07 Applied Medical Resources Corporation Laparoscopic surgical clamp
AU1011595A (en) * 1994-01-13 1995-07-20 Ethicon Inc. Spiral surgical tack
US5452836A (en) * 1994-02-07 1995-09-26 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with improved jaw closure and staple firing actuator mechanism
US5425740A (en) * 1994-05-17 1995-06-20 Hutchinson, Jr.; William B. Endoscopic hernia repair clip and method
DE4421536A1 (de) 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US5569306A (en) * 1995-06-06 1996-10-29 Thal; Raymond Knotless suture anchor assembly
WO1997039689A1 (en) * 1996-04-19 1997-10-30 Applied Medical Resources Corporation Grasping clip applier
US5816258A (en) * 1996-06-13 1998-10-06 General Surgical Innovations, Inc. Bladder neck suspension method
US6024748A (en) * 1996-07-23 2000-02-15 United States Surgical Corporation Singleshot anastomosis instrument with detachable loading unit and method
US6109500A (en) * 1996-10-04 2000-08-29 United States Surgical Corporation Lockout mechanism for a surgical stapler
JP2002514100A (ja) * 1996-10-24 2002-05-14 スピナル コンセプツ，インク． 脊椎を固定するための方法および装置
US5766250A (en) * 1996-10-28 1998-06-16 Medicinelodge, Inc. Ligament fixator for a ligament anchor system
US5954057A (en) * 1997-02-12 1999-09-21 Li Medical Technologies, Inc. Soft tissue suspension clip, clip assembly, emplacement tool and method
US5904692A (en) * 1997-04-14 1999-05-18 Mitek Surgical Products, Inc. Needle assembly and method for passing suture
US5960522A (en) * 1997-05-21 1999-10-05 Micron Electronics, Inc. Ribbon cable alligator clamp
US6099552A (en) * 1997-11-12 2000-08-08 Boston Scientific Corporation Gastrointestinal copression clips
AU733868B2 (en) * 1998-05-12 2001-05-31 Boston Scientific Limited Manual bone anchor placement devices

Also Published As

Publication number Publication date
SK281527B6 (sk) 2001-04-09
IL118327A0 (en) 1996-09-12
AU5237396A (en) 1996-12-05
SI0744397T1 (en) 2000-08-31
US20010020042A1 (en) 2001-09-06
US20020123529A1 (en) 2002-09-05
ATE192431T1 (de) 2000-05-15
CZ145096A3 (en) 1996-12-11
JPH08319266A (ja) 1996-12-03
NO305552B1 (no) 1999-06-21
PL314252A1 (en) 1996-11-25
CA2177007A1 (en) 1996-11-23
PT744397E (pt) 2000-09-29
NO962063D0 (no) 1996-05-21
EP0744397A3 (de) 1997-03-26
IL118327A (en) 2002-12-01
US6504057B2 (en) 2003-01-07
ES2147629T3 (es) 2000-09-16
GR3033416T3 (en) 2000-09-29
EP0744397B1 (de) 2000-05-03
CN1063437C (zh) 2001-03-21
HUP9601358A2 (en) 1997-05-28
ZA964035B (en) 1997-11-21
SK65196A3 (en) 1996-12-04
NO962063L (no) 1996-11-25
DE59605101D1 (de) 2000-06-08
AU701493B2 (en) 1999-01-28
MY113803A (en) 2002-05-31
DK0744397T3 (da) 2000-08-28
HUP9601358A3 (en) 1997-10-28
DE19518796A1 (de) 1996-11-28
HU9601358D0 (en) 1996-07-29
NZ286622A (en) 1997-08-22
PL183431B1 (pl) 2002-06-28
HRP960230A2 (en) 1997-12-31
AR002744A1 (es) 1998-04-29
JP3924018B2 (ja) 2007-06-06
TR199600421A2 (tr) 1997-03-21
KR960041152A (ko) 1996-12-19
CN1138029A (zh) 1996-12-18
CZ291622B6 (cs) 2003-04-16
CA2177007C (en) 2009-01-06
RU2164913C2 (ru) 2001-04-10
TW415936B (en) 2000-12-21
EP0744397A2 (de) 1996-11-27
HRP960230B1 (en) 2000-12-31

Similar Documents

Publication Publication Date Title
BR9602394A (pt) Guanididas de ácido alquenilcarboxílico processo para a sua preparação seus usos método para o tratamento de arritmias bem como medicamento
PT95099A (pt) Processo para a preparacao de amino acidos ciclicos bem como dos seus intermediarios
PT88261A (pt) Processo para a preparacao de nucleosidos com efeito terapeutico
PT88883A (pt) Processo para a preparacao de derivados n-manonojirimicina uteis como medicamentos
PT88200A (pt) Processo para a preparacao de uma composicao para o tratamento da pele
BR9503812A (pt) Composto composição farmacêutica utilização método de tratamento de um ser humano processo para a preparação de um composto
FI912619A7 (fi) Hyaluronihapon esterit, menetelmä niiden valmistamiseksi sekä hyaluronihapon estereitä sisältävät saniteetti- ja kirurgiset tuotteet
NO871408D0 (no) Forbedringer ved farmasoeytiske akseptable salter.
NO951885L (no) Fremgangsmåte for fremstilling av produkter inneholdende dobbelsalter av maursyre
DE3689932D1 (de) Amorfes Alumosilikat und Verfahren zu dessen Herstellung.
BR9205609A (pt) Processo ortomolecular de tratamento de doença falciforme
PT89249A (pt) Processo para a preparacao de novos derivados de piperidinilo 1,4-dissubstituido com actividade terapeutica
FI905584A7 (fi) Menetelmä 1-(aminometyyli)sykloheksaanietikkahapon valmistamiseksi
BR9600254A (pt) Composto processo para a sua preparação seus usos método para o tratamento de arritmias e medicamento contendo o mesmo
BR8806375A (pt) Processo para produzir fluoreto de titanio
ATA87388A (de) Neue purinylribofuranuronsaeurederivate, verfahren zu deren herstellung und sie enthaltende therapeutische praeparate
DE3852963D1 (de) Kristallines menschliches Proinsulin und Verfahren zu dessen Herstellung.
PT89195A (pt) Processo para a preparacao de derivados de triazole uteis como agentes anti-fungicos
PT88078A (pt) Processo para a preparacao de acidos quinolonocarboxilicos
BR8705716A (pt) Estirilariloxi-eter-sulfonatos,processo para sua preparacao e sua aplicacao,bem como combinacoes tenso-ativas
BR8804733A (pt) Processo para a producao de agentes de tratamento de texteis,bem como utilizacoes de tais agentes
PT83778B (pt) Processo para o tratamento de extractos vegetais
ES2020925B3 (es) Nuevas sales cristalinas de ariloxipropanolaminas, procedimiento para su preparacion y utilizacion de las mismas.
AU613355B2 (en) Method for treating skin diseases
BR9600370A (pt) Benzenossulfoniluréias e-tiouréias substituídas processo para a sua preparação seus usos e medicamento contendo as mesmas

Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements