ES2058908T3 - Procedimiento para la separacion y purificacion de sialil-transferasas. - Google Patents

Procedimiento para la separacion y purificacion de sialil-transferasas.

Info

Publication number
ES2058908T3
ES2058908T3 ES90906090T ES90906090T ES2058908T3 ES 2058908 T3 ES2058908 T3 ES 2058908T3 ES 90906090 T ES90906090 T ES 90906090T ES 90906090 T ES90906090 T ES 90906090T ES 2058908 T3 ES2058908 T3 ES 2058908T3
Authority
ES
Spain
Prior art keywords
specific
lacnac
alpha
sialyl
transferasas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90906090T
Other languages
English (en)
Inventor
M Abdul Mazid
Mohammed A Kashem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alberta Innovates
Original Assignee
Alberta Innovates
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alberta Innovates filed Critical Alberta Innovates
Application granted granted Critical
Publication of ES2058908T3 publication Critical patent/ES2058908T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

TRANSFERASAS DE SIALILO ESPECIFICAS (ST) SON UNAS ENZIMAS IMPORTANTES EN LA FABRICACION DE PORCIONES DE CARBOHIDRATO UTILES PARA PROPOSITOS FARMACEUTICOS Y PARA PROCEDIMIENTOS CLINICOS Y DE DIAGNOSTICO. LA INVENCION OFRECE METODOS SIMPLIFICADOS PARA AISLAR FORMAS ALTAMENTE ESPECIFICAS DE ESTAS ENZIMAS ST AL TOMAR VENTAJA DE LA AFINIDAD DEL ST PARA SU SUSTRATO ACEPTADOR EN LA PRESENCIA DE LOS ANALOGOS DE SIALILO-CMP, TALES COMO CDP. SE ILUSTRAN ESPECIFICAMENTE, EL AISLAMIENTO DE ALFA 2,3-ST , ESPECIFICO PARA LE ELEVADO C O LACNAC, Y ALFA 2,6-ST, ESPECIFICO PARA LACNAC.
ES90906090T 1989-04-12 1990-04-12 Procedimiento para la separacion y purificacion de sialil-transferasas. Expired - Lifetime ES2058908T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/336,932 US5059535A (en) 1989-04-12 1989-04-12 Process for the separation and purification of sialyl transferases

Publications (1)

Publication Number Publication Date
ES2058908T3 true ES2058908T3 (es) 1994-11-01

Family

ID=23318345

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90906090T Expired - Lifetime ES2058908T3 (es) 1989-04-12 1990-04-12 Procedimiento para la separacion y purificacion de sialil-transferasas.

Country Status (10)

Country Link
US (1) US5059535A (es)
EP (1) EP0470969B1 (es)
JP (1) JPH05500154A (es)
AT (1) ATE92523T1 (es)
AU (1) AU633912B2 (es)
CA (1) CA2051374C (es)
DE (1) DE69002623T2 (es)
DK (1) DK0470969T3 (es)
ES (1) ES2058908T3 (es)
WO (1) WO1990012090A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
DE4009630C2 (de) * 1990-03-26 1995-09-28 Reinhard Prof Dr Dr Brossmer CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
US5374655A (en) * 1991-06-10 1994-12-20 Alberta Research Council Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
CA2110582C (en) * 1991-06-10 2001-02-27 Andre P. Venot Modified sialyl lewis a compounds
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
US5352670A (en) * 1991-06-10 1994-10-04 Alberta Research Council Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
CA2110797C (en) * 1991-06-10 2001-02-20 Andre P. Venot Modified sialyl lewis x compounds
DK0632831T3 (da) * 1992-03-09 2003-03-24 Univ California Nukleinsyre, ekspressionsvektor og sammensætninger til identificering og syntese af rekombinante sialyltransferaser
WO1995018217A1 (en) * 1993-12-24 1995-07-06 The Institute Of Physical And Chemical Research Novel sugar-chain synthetase and process for producing the same
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
NZ542586A (en) 2003-04-09 2009-11-27 Biogenerix Ag Method of forming a covalent conjugate between a G-CSF peptide and PEG
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
EP3061461A1 (en) 2004-10-29 2016-08-31 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
US9029331B2 (en) 2005-01-10 2015-05-12 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
EP1871795A4 (en) 2005-04-08 2010-03-31 Biogenerix Ag COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US20080242607A1 (en) 2006-07-21 2008-10-02 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
CN101796063B (zh) 2007-04-03 2017-03-22 拉蒂奥法姆有限责任公司 使用糖聚乙二醇化g‑csf的治疗方法
US9493499B2 (en) 2007-06-12 2016-11-15 Novo Nordisk A/S Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
DE102008005159B4 (de) 2008-01-18 2018-02-15 Robert Bosch Gmbh Verfahren und Steuergerät zur Ansteuerung von Personenschutzmittel für ein Fahrzeug
DK2257311T3 (da) 2008-02-27 2014-06-30 Novo Nordisk As Konjugerede Faktor VIII-Molekyler
US12622876B2 (en) * 2016-08-22 2026-05-12 Lonza Sales Ag Methods of suppressing delivery of exosomes to liver and spleen
CA3181285A1 (en) * 2020-07-20 2022-01-27 Jessica BASSO Methods for extracting neutrophil serine proteases and treating dipeptidyl peptidase 1-mediated conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250262A (en) * 1979-12-14 1981-02-10 Forsyth Dental Infirmary For Children Method of preparing a purified glucosyltransferase
JPS58209980A (ja) * 1982-04-27 1983-12-07 Kyowa Hakko Kogyo Co Ltd 酵素の精製法
EP0263533A3 (en) * 1983-03-01 1990-05-30 C.R.C. Compagnia di Ricerca Chimica S.p.A. A method for preparing the cytidine monophosphate of 5-acetamido-3,5-dideoxy-d-glycero-d-galactononulosaminic acid
US4925796A (en) * 1986-03-07 1990-05-15 Massachusetts Institute Of Technology Method for enhancing glycoprotein stability

Also Published As

Publication number Publication date
AU633912B2 (en) 1993-02-11
US5059535A (en) 1991-10-22
CA2051374C (en) 1996-02-27
WO1990012090A1 (en) 1990-10-18
JPH05500154A (ja) 1993-01-21
ATE92523T1 (de) 1993-08-15
EP0470969B1 (en) 1993-08-04
DE69002623D1 (de) 1993-09-09
AU5528990A (en) 1990-11-05
EP0470969A1 (en) 1992-02-19
DK0470969T3 (da) 1994-01-03
DE69002623T2 (de) 1993-11-25
CA2051374A1 (en) 1990-10-13

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