BR0010552A - Proteìnas de transporte de anions orgânicos - Google Patents
Proteìnas de transporte de anions orgânicosInfo
- Publication number
- BR0010552A BR0010552A BR0010552-0A BR0010552A BR0010552A BR 0010552 A BR0010552 A BR 0010552A BR 0010552 A BR0010552 A BR 0010552A BR 0010552 A BR0010552 A BR 0010552A
- Authority
- BR
- Brazil
- Prior art keywords
- organic anion
- oatps
- transport proteins
- anion transport
- proteins
- Prior art date
Links
- 102000007990 Organic Anion Transporters Human genes 0.000 title 1
- 108010089503 Organic Anion Transporters Proteins 0.000 title 1
- 108091006172 SLC21 Proteins 0.000 abstract 4
- 102100032846 Solute carrier organic anion transporter family member 1A2 Human genes 0.000 abstract 4
- 150000002891 organic anions Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
"PROTEìNAS DE TRANSPORTE DE ANIONS ORGâNICOS". A presente invenção mostra seq³ências de ácidos nucléicos e aminoácidos para novas proteinas de transferência de anion orgânico ("OATPs"). A invenção encampa as OATPs aqui descritas, junto com os vetores contendo as seq³ências de CDNA, células hospedeiras contendo os vetores e polipeptideos tendo toda ou parte de uma OATP. Também encampados são usos para OATPs para alvejamento de drogas para órgãos específicos e para modulação de concentração de substratos endógenos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13508199P | 1999-05-20 | 1999-05-20 | |
| PCT/US2000/013939 WO2000071566A2 (en) | 1999-05-20 | 2000-05-19 | Novel organic anion transport proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0010552A true BR0010552A (pt) | 2002-02-13 |
Family
ID=22466450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0010552-0A BR0010552A (pt) | 1999-05-20 | 2000-05-19 | Proteìnas de transporte de anions orgânicos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1183270B1 (pt) |
| JP (1) | JP4071442B2 (pt) |
| CN (1) | CN1351612A (pt) |
| AT (1) | ATE468354T1 (pt) |
| AU (1) | AU769361B2 (pt) |
| BR (1) | BR0010552A (pt) |
| CA (1) | CA2374729C (pt) |
| DE (1) | DE60044433D1 (pt) |
| ES (1) | ES2343672T3 (pt) |
| HU (1) | HU228779B1 (pt) |
| IL (2) | IL145866A0 (pt) |
| PL (1) | PL201687B1 (pt) |
| WO (1) | WO2000071566A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001021792A1 (en) * | 1999-09-21 | 2001-03-29 | Chugai Seiyaku Kabushiki Kaisha | Transporter genes oatp-b, c, d and e |
| US20020165357A1 (en) * | 2001-03-12 | 2002-11-07 | Millennium Pharmaceuticals, Inc. | 38554, 57301 and 58324, human organic ion transporters and uses therefor |
| AU2001263814A1 (en) * | 2000-03-27 | 2001-10-08 | Bayer Aktiengesellschaft | Regulation of human oatp2-related protein |
| GB0013105D0 (en) * | 2000-05-30 | 2000-07-19 | Univ Bristol | Therapeutic compounds |
| AU2002219083A1 (en) * | 2000-11-09 | 2002-05-21 | Bayer Aktiengesellschaft | Regulation of human oat-like protein |
| EP1395680A2 (en) * | 2001-05-18 | 2004-03-10 | AstraZeneca AB | Methods |
| GB0213580D0 (en) * | 2002-06-13 | 2002-07-24 | Astrazeneca Ab | Methods |
| EP1590661A4 (en) * | 2002-11-05 | 2006-07-26 | Roskamp Res Llc | GENE OF PROTEIN-4 (OATPRP4) BITOURETTE SYNDROME AND RELATED DISEASES RELATED TO THE POLYPEPTIDE FOR DENTRANSPORT OF ORGANIC ANIONS |
| CN102373231A (zh) * | 2010-08-13 | 2012-03-14 | 中南大学 | 一种含有oatp1b1启动子和报告基因的重组质粒及筛选oatp1b1诱导剂的方法 |
| JP6417554B2 (ja) | 2012-09-11 | 2018-11-07 | コーニング インコーポレイテッド | 薬物輸送タンパク質および/または薬物代謝酵素をコード化する遺伝子を一過的に過剰発現する摂取できる凍結保存細胞 |
| DK2848262T3 (da) * | 2013-09-12 | 2021-02-08 | Smartdyelivery Gmbh | Cellespecifik målretning ved hjælp af nanostrukturerede bærersystemer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5589358A (en) * | 1993-12-29 | 1996-12-31 | Univ Wake Forest | Ileal bile acid transporter compositions and methods |
| EP0900273A2 (en) * | 1996-02-22 | 1999-03-10 | Introgene B.V. | A family of organic anion transporters, nucleic acids encoding them, cells comprising them and methods for using them |
-
2000
- 2000-05-19 BR BR0010552-0A patent/BR0010552A/pt not_active Application Discontinuation
- 2000-05-19 AT AT00937636T patent/ATE468354T1/de not_active IP Right Cessation
- 2000-05-19 CN CN00807838.6A patent/CN1351612A/zh active Pending
- 2000-05-19 EP EP00937636A patent/EP1183270B1/en not_active Expired - Lifetime
- 2000-05-19 DE DE60044433T patent/DE60044433D1/de not_active Expired - Lifetime
- 2000-05-19 IL IL14586600A patent/IL145866A0/xx active IP Right Grant
- 2000-05-19 AU AU52780/00A patent/AU769361B2/en not_active Expired
- 2000-05-19 JP JP2000619821A patent/JP4071442B2/ja not_active Expired - Lifetime
- 2000-05-19 ES ES00937636T patent/ES2343672T3/es not_active Expired - Lifetime
- 2000-05-19 HU HU0201303A patent/HU228779B1/hu unknown
- 2000-05-19 CA CA002374729A patent/CA2374729C/en not_active Expired - Lifetime
- 2000-05-19 WO PCT/US2000/013939 patent/WO2000071566A2/en not_active Ceased
- 2000-05-19 PL PL351652A patent/PL201687B1/pl unknown
-
2001
- 2001-10-11 IL IL145866A patent/IL145866A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0201303A2 (en) | 2002-08-28 |
| CA2374729A1 (en) | 2000-11-30 |
| HU228779B1 (en) | 2013-05-28 |
| JP2003500039A (ja) | 2003-01-07 |
| WO2000071566A2 (en) | 2000-11-30 |
| IL145866A (en) | 2008-11-26 |
| AU5278000A (en) | 2000-12-12 |
| IL145866A0 (en) | 2002-07-25 |
| WO2000071566A3 (en) | 2001-01-25 |
| ES2343672T3 (es) | 2010-08-06 |
| JP4071442B2 (ja) | 2008-04-02 |
| ATE468354T1 (de) | 2010-06-15 |
| CN1351612A (zh) | 2002-05-29 |
| EP1183270A4 (en) | 2005-10-19 |
| DE60044433D1 (de) | 2010-07-01 |
| PL201687B1 (pl) | 2009-04-30 |
| AU769361B2 (en) | 2004-01-22 |
| HUP0201303A3 (en) | 2004-12-28 |
| EP1183270B1 (en) | 2010-05-19 |
| CA2374729C (en) | 2009-01-13 |
| PL351652A1 (en) | 2003-05-19 |
| EP1183270A2 (en) | 2002-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |