BRPI0318325B8 - compostos miméticos de beta-fita - Google Patents

compostos miméticos de beta-fita

Info

Publication number
BRPI0318325B8
BRPI0318325B8 BRPI0318325A BR0318325A BRPI0318325B8 BR PI0318325 B8 BRPI0318325 B8 BR PI0318325B8 BR PI0318325 A BRPI0318325 A BR PI0318325A BR 0318325 A BR0318325 A BR 0318325A BR PI0318325 B8 BRPI0318325 B8 BR PI0318325B8
Authority
BR
Brazil
Prior art keywords
beta
tape
strand
mimetic compounds
disclosed
Prior art date
Application number
BRPI0318325A
Other languages
English (en)
Other versions
BR0318325A (pt
BRPI0318325B1 (pt
Inventor
Masakatsu Eguchi
Uk Chung Jae
Kahn Michael
Hwan Moon Sung
Original Assignee
Choongwae Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choongwae Pharma Corp filed Critical Choongwae Pharma Corp
Publication of BR0318325A publication Critical patent/BR0318325A/pt
Publication of BRPI0318325B1 publication Critical patent/BRPI0318325B1/pt
Publication of BRPI0318325B8 publication Critical patent/BRPI0318325B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

miméticos de beta-fita e método relacionado aos mesmos. são mostrados compostos conformacionalmente comprimidos, que mimetizam a estrutura secundária de regiões de (beta)-fita de peptídeos biologicamente ativos e proteínas. tais estruturas miméticas de (beta)-fita têm utilidade em uma faixa extensa faixa de campos, icluindo uso como agentes diagnósticos e agentes terapêuticos. também descritas estão bibliotecas contendo as estruturas miméticas de (beta)-fita desta invenção bem como métodos para avaliar as mesmas de forma a identificar os membros biologicamente ativos.
BRPI0318325A 2003-05-30 2003-05-30 compostos miméticos de beta-fita BRPI0318325B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/017188 WO2004108731A1 (en) 2003-05-30 2003-05-30 Beta-strand mimetics and method relating thereto

Publications (3)

Publication Number Publication Date
BR0318325A BR0318325A (pt) 2006-07-18
BRPI0318325B1 BRPI0318325B1 (pt) 2019-06-04
BRPI0318325B8 true BRPI0318325B8 (pt) 2021-05-25

Family

ID=33509890

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0318325A BRPI0318325B8 (pt) 2003-05-30 2003-05-30 compostos miméticos de beta-fita

Country Status (12)

Country Link
EP (1) EP1646633B1 (pt)
JP (1) JP4546923B2 (pt)
KR (1) KR101018453B1 (pt)
CN (1) CN1802378A (pt)
AT (1) ATE428713T1 (pt)
AU (1) AU2003249672B2 (pt)
BR (1) BRPI0318325B8 (pt)
CA (1) CA2527375C (pt)
DE (1) DE60327263D1 (pt)
ES (1) ES2323172T3 (pt)
NZ (1) NZ543790A (pt)
WO (1) WO2004108731A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077040A2 (en) * 2004-02-11 2005-08-25 Rensselaer Polytechnic Institute Compositions and methods for treating amyotrophic lateral sclerosis (als)
CN102906566A (zh) 2010-02-03 2013-01-30 株式会社棱镜生物实验室 与天然变性蛋白质结合的化合物及其筛选方法
AU2017384317C1 (en) 2016-12-21 2022-06-30 Japan Tobacco Inc. PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF
SMT202200088T1 (it) * 2017-07-20 2022-03-21 Bristol Myers Squibb Co Procedimento per la preparazione di n-((1r,2s,sr)-5-(tert-butilammino)-2-((s)-3-(7-tert-butilpirazolo[1,5-a][1,3,5]triazin-4-ilammino)-2-ossopirrolidin-1-il)cicloesil)acetammide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2948535A1 (de) * 1979-12-03 1981-06-25 Basf Ag, 6700 Ludwigshafen Dichloracetamide, herbizide mittel, die acetanilide als herbizide wirkstoffe und diese dichloracetamide als antagonistische mittel enthalten, sowie ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
DE3120859A1 (de) * 1981-05-26 1982-12-23 Basf Ag, 6700 Ludwigshafen Dihalogenacetamide, verfahren zu ihrer herstellung und herbizide mittel, die acetanilide als herbizide wirkstoffe und diese dihalogenacetamide als antagonistische mittel enthalten
AU2002303779A1 (en) * 2001-05-16 2002-11-25 Molecumetics, Ltd. Reverse-turn mimetics and methods relating thereto

Also Published As

Publication number Publication date
ES2323172T3 (es) 2009-07-08
CN1802378A (zh) 2006-07-12
JP2006526568A (ja) 2006-11-24
EP1646633B1 (en) 2009-04-15
CA2527375A1 (en) 2004-12-16
AU2003249672A1 (en) 2005-01-04
ATE428713T1 (de) 2009-05-15
EP1646633A1 (en) 2006-04-19
DE60327263D1 (de) 2009-05-28
BR0318325A (pt) 2006-07-18
BRPI0318325B1 (pt) 2019-06-04
AU2003249672B2 (en) 2008-03-06
CA2527375C (en) 2010-08-10
JP4546923B2 (ja) 2010-09-22
WO2004108731A1 (en) 2004-12-16
NZ543790A (en) 2009-09-25
KR20060056896A (ko) 2006-05-25
KR101018453B1 (ko) 2011-03-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 3A E 4A A NUIDADES.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/05/2003 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 19A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2673 DE 29-03-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.