BRPI0407221A - Extrato de geléia de wharton, método para a obtenção de uma célula progenitora humana, métodos para a produção de uma população de células, populações de células e método para a produção de tecido ósseo - Google Patents

Extrato de geléia de wharton, método para a obtenção de uma célula progenitora humana, métodos para a produção de uma população de células, populações de células e método para a produção de tecido ósseo

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Publication number
BRPI0407221A
BRPI0407221A BR0407221-9A BRPI0407221A BRPI0407221A BR PI0407221 A BRPI0407221 A BR PI0407221A BR PI0407221 A BRPI0407221 A BR PI0407221A BR PI0407221 A BRPI0407221 A BR PI0407221A
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BR
Brazil
Prior art keywords
cell
producing
obtaining
methods
bone tissue
Prior art date
Application number
BR0407221-9A
Other languages
English (en)
Inventor
John E Davies
Dolores Baksh
Rahul Sarugaser
Antony David Sutton Lickorish
Original Assignee
John E Davies
Dolores Baksh
Rahul Sarugaser
Morris Hosseini
Antony David Sutton Lickorish
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John E Davies, Dolores Baksh, Rahul Sarugaser, Morris Hosseini, Antony David Sutton Lickorish filed Critical John E Davies
Publication of BRPI0407221A publication Critical patent/BRPI0407221A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

"EXTRATO DE GELéIA DE WHARTON, MéTODO PARA A OBTENçãO DE UMA CéLULA PROGENITORA HUMANA, MéTODOS PARA A PRODUçãO DE UMA POPULAçãO DE CéLULAS, POPULAçõES DE CéLULAS E MéTODO PARA A PRODUçãO DE TECIDO óSSEO". As células progenitoras humanas são extraídas da geléia de Wharton que se encontra dentro de uma zona de perivasculatura do cordão umbilical humano. A população das células progenitoras prolifera rapidamente, e abriga as células osteoprogenitoras e as células MHC -/-, e elas são úteis no desenvolvimento e no reparo de tecidos humanos, incluindo os ossos.
BR0407221-9A 2003-02-11 2004-02-10 Extrato de geléia de wharton, método para a obtenção de uma célula progenitora humana, métodos para a produção de uma população de células, populações de células e método para a produção de tecido ósseo BRPI0407221A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44627503P 2003-02-11 2003-02-11
PCT/CA2004/000182 WO2004072273A1 (en) 2003-02-11 2004-02-10 Progenitor cells from wharton's jelly of human umbilical cord

Publications (1)

Publication Number Publication Date
BRPI0407221A true BRPI0407221A (pt) 2006-01-31

Family

ID=32869477

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0407221-9A BRPI0407221A (pt) 2003-02-11 2004-02-10 Extrato de geléia de wharton, método para a obtenção de uma célula progenitora humana, métodos para a produção de uma população de células, populações de células e método para a produção de tecido ósseo

Country Status (13)

Country Link
US (5) US7547546B2 (pt)
EP (2) EP2277992A3 (pt)
JP (1) JP4790592B2 (pt)
KR (1) KR101077760B1 (pt)
AT (1) ATE478941T1 (pt)
AU (2) AU2004210891B2 (pt)
BR (1) BRPI0407221A (pt)
CA (1) CA2515469C (pt)
DE (1) DE602004028803D1 (pt)
ES (1) ES2351386T3 (pt)
IL (2) IL170221A (pt)
PT (1) PT1594957E (pt)
WO (1) WO2004072273A1 (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2206772A3 (en) 2000-12-06 2010-08-04 Robert J. Hariri Method of collecting placental stem cells
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
CA2437957C (en) 2001-02-14 2014-04-22 Robert J. Hariri Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
EP2336299A1 (en) * 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US7700090B2 (en) 2002-02-13 2010-04-20 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
WO2004072273A1 (en) 2003-02-11 2004-08-26 Davies John E Progenitor cells from wharton's jelly of human umbilical cord
ES2564044T3 (es) * 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US8491883B2 (en) 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
AU2005322060B2 (en) * 2003-06-27 2011-11-17 Ethicon Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
SG146691A1 (en) 2003-10-08 2008-10-30 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
EP2597149A1 (en) * 2004-08-16 2013-05-29 CellResearch Corporation Pte Ltd Isolation, cultivation and uses of stem/progenitor cells
US20060153815A1 (en) * 2004-12-21 2006-07-13 Agnieszka Seyda Tissue engineering devices for the repair and regeneration of tissue
US20060171930A1 (en) * 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
WO2006083394A2 (en) * 2004-12-21 2006-08-10 Ethicon, Inc. Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
WO2006071802A2 (en) 2004-12-23 2006-07-06 Ethicon Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
WO2006071777A2 (en) * 2004-12-23 2006-07-06 Ethicon Incorporated Soft tissue repair and regeneration using postpartum-derived cells and cell products
WO2006071773A2 (en) * 2004-12-23 2006-07-06 Ethicon Incoporated Treatment of osteochondral diseases using postpartum-derived cells and products thereof
CA2624925C (en) 2005-10-13 2014-09-30 Anthrogenesis Corporation Immunomodulation using placental stem cells
WO2007059084A2 (en) * 2005-11-14 2007-05-24 The New England Medical Center Hospitals, Inc. Methods for preparing cord matrix stem cells (cmsc) for long term storage and for preparing a segment of umbilical cord for cryopreservation
CN101374946B (zh) 2005-12-16 2017-07-18 伊西康公司 用于在组织相容性不匹配的移植中抑制有害的免疫反应的组合物和方法
AU2006327073B2 (en) * 2005-12-19 2012-08-30 Ethicon, Inc. In vitro expansion of postpartum derived cells in roller bottles
EP1976980B1 (en) * 2005-12-22 2019-03-06 Jane Ennis Viable cells from frozen umbilical cord tissue
SG170789A1 (en) * 2005-12-28 2011-05-30 Ethicon Inc Treatment of peripheral vascular disease using postpartum-derived cells
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
ES2708933T3 (es) 2005-12-29 2019-04-12 Celularity Inc Poblaciones de células madre placentarias
EP1989294A4 (en) * 2006-03-01 2009-09-23 Regenerative Medicine Inst COMPOSITIONS AND POPULATIONS OF CELLS OBTAINED FROM THE UMBILICAL CORD AND METHODS OF PRODUCING THE SAME
KR101507174B1 (ko) * 2006-05-05 2015-04-01 존 이. 다비스 면역 특권 및 조절 전구 세포
US20080050814A1 (en) * 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2007146105A2 (en) * 2006-06-05 2007-12-21 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2007146123A2 (en) * 2006-06-09 2007-12-21 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US20090124007A1 (en) * 2006-11-15 2009-05-14 Seoul National University Industry Foundation Method for the Simultaneous Primary-Isolation and Expansion of Endothelial Stem/Progenitor Cell and Mesenchymal Stem Cell Derived From Mammal Including Human Umbilical Cord
KR100902569B1 (ko) * 2007-01-19 2009-06-11 재단법인서울대학교산학협력재단 인간 탯줄 유래 중간엽 줄기세포 및 이의 확립방법
EP2099290A4 (en) * 2006-12-07 2010-01-13 Teva Pharma PROCESS FOR GENERATING AND EXPANDING PROGENITOR CELLS OF TISSUES AND TISSUE CELLS MILLED FROM INTACT BONE MARROW OR UMBILICAL INTACT CORD TISSUE
KR101569168B1 (ko) 2007-02-12 2015-11-13 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
WO2009021333A1 (en) * 2007-08-14 2009-02-19 Tissue Regeneration Therapeutics Inc. Blood vessel extraction from umbilical cord
US12129481B2 (en) 2007-09-13 2024-10-29 Reprobiogen Inc. Use of cells derived from first trimester umbilical cord tissue
US10925903B2 (en) 2007-09-13 2021-02-23 Reprobiogen Inc. Use of cells derived from first trimester umbilical cord tissue
CA2630708C (en) * 2007-09-13 2017-08-01 Clifford L. Librach Method of isolation and use of cells derived from first trimester umbilical cord tissue
CA2700617C (en) 2007-09-28 2018-11-06 Celgene Cellular Therapeutics Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US8034329B2 (en) * 2007-10-05 2011-10-11 Advanced Technologies And Regenerative Medicine, Llc Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells
US20090142836A1 (en) * 2007-11-28 2009-06-04 Organogenesis, Inc. Bioengineered tissue constructs and methods for production and use
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
KR20170005148A (ko) 2008-04-21 2017-01-11 티슈 리제너레이션 쎄라퓨틱스, 인코포레이티드 생물학적 또는 화학적 물질에 대한 예방 또는 치료를 위한 유전적으로 변형된 인간 탯줄 혈관주위 세포
DK2330889T3 (en) 2008-08-20 2017-01-30 Anthrogenesis Corp Improved cell composition and process for making the same
JP5950577B2 (ja) 2008-08-20 2016-07-13 アンスロジェネシス コーポレーション 単離胎盤細胞を使用した脳卒中の治療
HRP20130812T1 (en) 2008-08-22 2013-09-30 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
CN102282252B (zh) 2008-11-19 2017-07-04 人类起源公司 羊膜来源的贴壁细胞
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
BRPI0923068B1 (pt) 2008-12-19 2021-05-25 Advanced Technologies And Regenerative Medicine, Llc Uso de células derivadas de tecido de cordão umbilical para tratar um paciente tendo uma doença, distúrbio ou injúria pulmonar
US8771677B2 (en) 2008-12-29 2014-07-08 Vladimir B Serikov Colony-forming unit cell of human chorion and method to obtain and use thereof
CN102498204B (zh) * 2009-03-26 2015-02-04 德普伊新特斯产品有限责任公司 人脐带组织细胞作为用于阿尔茨海默病的疗法
CN102712905A (zh) * 2009-12-18 2012-10-03 C.B.B.生命线生物技术有限公司 从脐带组织分离包括间充质祖细胞亚群的单核细胞和包括内皮祖细胞亚群的血管细胞的方法
US20110293667A1 (en) * 2010-01-14 2011-12-01 Dolores Baksh Bioengineered Tissue Constructs and Methods for Producing and Using Thereof
ES2646750T3 (es) 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
JP5591995B2 (ja) 2010-03-30 2014-09-17 イストセル，エセ．エレ． ウォートンジェリー臍帯由来の新規の生体材料
IL250234B2 (en) 2010-04-07 2023-10-01 Anthrogenesis Llc Angiogenesis using placental stem cells
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
WO2011153205A1 (en) 2010-06-01 2011-12-08 Auxocell Laboratories, Inc. Native wharton's jelly stem cells and their purification
KR20180099915A (ko) 2010-07-13 2018-09-05 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
CN103168236B (zh) 2010-08-23 2016-01-20 哈佛大学管理委员会 用于膜电位测定的光遗传学探针
AU2011352036A1 (en) 2010-12-31 2013-07-18 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
CN104220081A (zh) 2011-06-01 2014-12-17 人类起源公司 利用胎盘干细胞治疗疼痛
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
ES2725564T3 (es) 2011-11-08 2019-09-24 Auxocell Laboratories Inc Sistemas y métodos de procesamiento celular
JP6301263B2 (ja) 2011-12-23 2018-03-28 デピュイ・シンセス・プロダクツ・インコーポレイテッド ヒト臍帯組織由来細胞の検出
PL3321355T3 (pl) 2011-12-30 2021-12-27 Amit Patel Sposoby i kompozycje do klinicznego pozyskiwania komórek alogenicznych oraz zastosowania terapeutyczne
US8940294B2 (en) 2012-03-02 2015-01-27 Tissuetech, Inc. Methods of isolating and culturing stem cells
WO2013149003A1 (en) 2012-03-28 2013-10-03 Purdue Research Foundation Methods and systems useful for foodborne pathogen detection
US9670457B2 (en) * 2012-05-08 2017-06-06 Stem Cell Reserve Lp Stem cells and matrix from cord tissue
EP2756754B1 (de) 2013-01-17 2017-01-04 Vita 34 Ag Verfahren zur Behandlung von Nabelschnurgewebe, insbesondere im Zusammenhang mit der Konservierung des Gewebes
AU2014215458A1 (en) 2013-02-05 2015-08-13 Anthrogenesis Corporation Natural killer cells from placenta
JP2016509863A (ja) 2013-03-15 2016-04-04 ラーソン、マルクス カーレ、トールレイフＬＡＲＳＳＯＮ， Ｍａｒｃｕｓ Ｋａｒｅ， Ｔｏｒｌｅｉｆ 細胞、臍帯血収集のための方法及び装置、並びに細胞の単離のための方法及び装置
US10400211B1 (en) 2014-04-28 2019-09-03 Donnie Rudd Cell composition for tissue regeneration
US9993748B2 (en) 2014-08-11 2018-06-12 Auxocell Laboratories, Inc. Centrifuge clip and method
USD748462S1 (en) 2014-08-11 2016-02-02 Auxocell Laboratories, Inc. Centrifuge clip
US10542743B2 (en) 2015-01-05 2020-01-28 Hygieia Therapeutics Sdn Bhd Isolation, expansion and characterization of wharton's jelly mesenchymal stem cells
WO2017053701A1 (en) 2015-09-23 2017-03-30 Osiris Therapeutics, Inc. Umbilical tissue compositions and methods of use
WO2018073615A1 (en) 2016-10-21 2018-04-26 Longboat Explorers Ab Methods and compositions for generating hematopoietic cells
US20210369786A1 (en) * 2017-10-27 2021-12-02 Alis Pharma Ltd. Fetal tissue extract, methods for producing the extract, and the use thereof
KR102777940B1 (ko) * 2017-12-22 2025-03-11 키에시 파르마슈티시 엣스. 피. 에이. 중간엽 기질세포 및 탯줄로부터 중간엽 기질세포를 얻기 위한 방법
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
TWI882956B (zh) 2018-04-12 2025-05-11 新加坡商細胞研究私人有限公司 一種誘導或改善間質幹細胞傷口癒合特性的方法
US12460178B2 (en) 2018-04-12 2025-11-04 Cellresearch Corporation Pte. Ltd. Method of inducing or improving wound healing properties of mesenchymal stem cells
US20210269768A1 (en) 2018-07-02 2021-09-02 Vetbiobank Neonatal stromal cells having low mhc-i expression and uses therof
WO2020256628A1 (en) 2019-06-20 2020-12-24 Amniotics Ab An apparatus for filtering amniotic fluid
WO2021003254A1 (en) * 2019-07-01 2021-01-07 Auxocell Laboratories, Inc. Cryopreservation medium comprising a tissue extract
JP7714535B2 (ja) 2019-10-18 2025-07-29 アムニオティクス・アーベー 羊水およびそれに由来する細胞から羊水間葉系幹細胞を得るためのプロセスならびに装置
WO2021092199A1 (en) 2019-11-08 2021-05-14 Kansas State University Research Foundation Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells
EP3909593A1 (en) 2020-05-15 2021-11-17 Rigshospitalet Stem cells for treating skin lesions
US12435308B2 (en) 2020-11-06 2025-10-07 Amniotics Ab Immunomodulation by amniotic fluid mesenchymal stem cells
US20240400622A1 (en) 2021-09-23 2024-12-05 President And Fellows Of Harvard College Genetically encoded voltage indicators and uses thereof
WO2023223303A1 (en) 2022-05-20 2023-11-23 Alt Atlas Ltd. Novel cell lines and systems and methods for a machine learning manufacturing software platform that optimize unique functional ingredients and solutions for the biotech and foodtech industries

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2578743B3 (fr) * 1985-03-13 1987-06-12 Bontemps Raymond Procede de fabrication d'une preparation medicamenteuse a base de substance mesenchymateuse du type microsepteurs
SU1708328A1 (ru) * 1989-07-11 1992-01-30 Кемеровский государственный медицинский институт Способ изготовлени сосудистого протеза
US5919702A (en) * 1996-10-23 1999-07-06 Advanced Tissue Science, Inc. Production of cartilage tissue using cells isolated from Wharton's jelly
US20050158289A1 (en) * 1999-07-07 2005-07-21 Simmons Paul J. Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals
US7670628B2 (en) * 1999-07-07 2010-03-02 Angioblast Systems, Inc. Mesenchymal precursor cell
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) * 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
CA2381292C (en) * 1999-08-05 2016-05-24 Mcl Llc Multipotent adult stem cells and methods for isolation
US20020045260A1 (en) * 2000-10-17 2002-04-18 Shih-Chieh Hung Method of isolating mesenchymal stem cells
ES2328460T3 (es) * 2001-04-24 2009-11-13 Dolores Baksh Poblaciones de celulas progenitoras, expansion de las mismas y crecimiento de tipos de celulas no hematopoyeticas y tejidos provenientes de las mismas.
US7736892B2 (en) * 2002-02-25 2010-06-15 Kansas State University Research Foundation Cultures, products and methods using umbilical cord matrix cells
US20030161818A1 (en) * 2002-02-25 2003-08-28 Kansas State University Research Foundation Cultures, products and methods using stem cells
WO2004072273A1 (en) 2003-02-11 2004-08-26 Davies John E Progenitor cells from wharton's jelly of human umbilical cord
AU2003304250A1 (en) * 2003-06-27 2005-01-13 Universite Laval Method of isolating cells from umbilical cord
ES2564044T3 (es) 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
US20080113434A1 (en) 2004-03-05 2008-05-15 Davies John E Serum-Free Suspension Culture System For Mesenchymal Progenitor Cells
EP1976980B1 (en) 2005-12-22 2019-03-06 Jane Ennis Viable cells from frozen umbilical cord tissue
EP1989294A4 (en) 2006-03-01 2009-09-23 Regenerative Medicine Inst COMPOSITIONS AND POPULATIONS OF CELLS OBTAINED FROM THE UMBILICAL CORD AND METHODS OF PRODUCING THE SAME
KR101507174B1 (ko) 2006-05-05 2015-04-01 존 이. 다비스 면역 특권 및 조절 전구 세포

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