BRPI0407845A - formulação intranasal de rotigotina - Google Patents

formulação intranasal de rotigotina

Info

Publication number
BRPI0407845A
BRPI0407845A BRPI0407845-4A BRPI0407845A BRPI0407845A BR PI0407845 A BRPI0407845 A BR PI0407845A BR PI0407845 A BRPI0407845 A BR PI0407845A BR PI0407845 A BRPI0407845 A BR PI0407845A
Authority
BR
Brazil
Prior art keywords
rotigotine
intranasal
intranasal formulation
formulation
cyclodextrin
Prior art date
Application number
BRPI0407845-4A
Other languages
English (en)
Inventor
Robert Kraemer
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of BRPI0407845A publication Critical patent/BRPI0407845A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"FORMULAçãO INTRANASAL DE ROTIGOTINA". A invenção é relacionada a uma formulação líquida farmacêutica intranasal que compreende um sal ácido de adição farmaceuticamente aceitável de rotigotina e <244>-cyclodextrina, preferivelmente na forma de uma solução tampão aquosa com uma viscosidade de 0,5-1,5 mm¬ 2¬/S.
BRPI0407845-4A 2003-12-23 2004-12-22 formulação intranasal de rotigotina BRPI0407845A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03029680A EP1547592A1 (en) 2003-12-23 2003-12-23 Intranasal formulation of rotigotine
PCT/EP2004/014626 WO2005063236A1 (en) 2003-12-23 2004-12-22 Intranasal formulation of rotigotine

Publications (1)

Publication Number Publication Date
BRPI0407845A true BRPI0407845A (pt) 2006-02-14

Family

ID=34530709

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407845-4A BRPI0407845A (pt) 2003-12-23 2004-12-22 formulação intranasal de rotigotina

Country Status (27)

Country Link
US (1) US7683040B2 (pt)
EP (2) EP1547592A1 (pt)
JP (1) JP4430067B2 (pt)
KR (1) KR100718760B1 (pt)
CN (1) CN100374112C (pt)
AT (1) ATE326961T1 (pt)
AU (1) AU2004308641B2 (pt)
BR (1) BRPI0407845A (pt)
CA (1) CA2516400C (pt)
CY (1) CY1105131T1 (pt)
DE (1) DE602004000982T2 (pt)
DK (1) DK1605932T3 (pt)
EA (1) EA008005B1 (pt)
ES (1) ES2262122T3 (pt)
HR (1) HRP20060240T3 (pt)
IL (1) IL170297A (pt)
IS (1) IS2310B (pt)
MX (1) MXPA05008909A (pt)
NO (1) NO20054018L (pt)
NZ (1) NZ541875A (pt)
PL (1) PL1605932T3 (pt)
PT (1) PT1605932E (pt)
RS (1) RS50534B (pt)
SI (1) SI1605932T1 (pt)
UA (1) UA79196C2 (pt)
WO (1) WO2005063236A1 (pt)
ZA (1) ZA200506550B (pt)

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US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8246979B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE60204229T2 (de) 2002-12-02 2006-02-02 Schwarz Pharma Ag Verabreichung von Rotigotine zur Behandlung der Parkinson'schen Krankheit durch Iontophorese
DE10261696A1 (de) * 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
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EP1547592A1 (en) 2003-12-23 2005-06-29 Schwarz Pharma Ag Intranasal formulation of rotigotine
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TWI392670B (zh) * 2006-06-22 2013-04-11 Ucb Pharma Gmbh 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途
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RS54235B1 (sr) 2007-11-28 2015-12-31 Ucb Pharma Gmbh Polimorfni oblik rotigotina
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HRP20181173T1 (hr) 2009-12-22 2018-09-21 Ucb Biopharma Sprl Polivinilpirolidon za stabilizaciju čvrste disperzije nekristalnog oblika rotigotina
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DE102012013439A1 (de) 2012-07-03 2014-01-23 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor
WO2013075822A1 (en) 2011-11-22 2013-05-30 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system (tts) with rotigotine
DE102012013421A1 (de) 2012-07-03 2014-01-09 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TTS) mit Rotigotin
CN103768043B (zh) * 2012-10-22 2015-12-09 苏州药明康德新药开发股份有限公司 采用羟丙基-β-环糊精配制四氢化萘类化合物均一稳定溶液的方法
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
CA2916183C (en) 2013-07-03 2022-03-29 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with electronic component
US10598672B2 (en) 2014-02-18 2020-03-24 Cyrano Therapeutics, Inc. Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
JP6895755B2 (ja) 2014-05-20 2021-06-30 エルテーエス ローマン テラピー−ジステーメ アーゲー 経皮送達システムにおける活性薬剤の放出を調節するための方法
JP6573913B2 (ja) 2014-05-20 2019-09-11 エルテーエス ローマン テラピー−ジステーメ アーゲー ロチゴチンを含む経皮送達システム
EP4238580A3 (en) 2014-05-20 2023-10-25 LTS Lohmann Therapie-Systeme AG Transdermal delivery system including an interface mediator
US9956201B2 (en) 2014-07-21 2018-05-01 Spriaso Llc Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms
CN110917125B (zh) * 2020-01-02 2022-08-12 安徽中医药大学 一种罗替戈汀鼻用胶束温敏凝胶的制备方法
WO2021194893A1 (en) 2020-03-24 2021-09-30 Cyrano Therapeutics, Inc. Treatment of chemosensory dysfunction from a coronavirus infection
KR20240134157A (ko) * 2022-01-06 2024-09-06 시라노 테라퓨틱스, 아이엔씨. 파킨슨 치료제의 개선된 코 투여
CN118697690B (zh) * 2024-05-31 2025-03-21 纳索菲德(上海)制药技术有限公司 一种巴氯芬鼻脑递释组合物

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Also Published As

Publication number Publication date
CA2516400C (en) 2009-10-27
IS2310B (is) 2007-11-15
HK1083596A1 (en) 2006-07-07
EP1547592A1 (en) 2005-06-29
CY1105131T1 (el) 2009-11-04
CN1777422A (zh) 2006-05-24
NZ541875A (en) 2008-08-29
ES2262122T3 (es) 2006-11-16
EP1605932B1 (en) 2006-05-24
MXPA05008909A (es) 2005-10-05
AU2004308641B2 (en) 2006-10-26
DE602004000982D1 (de) 2006-06-29
NO20054018L (no) 2005-08-30
KR20060040578A (ko) 2006-05-10
ATE326961T1 (de) 2006-06-15
AU2004308641A1 (en) 2005-07-14
RS50534B (sr) 2010-05-07
PL1605932T3 (pl) 2006-09-29
PT1605932E (pt) 2006-08-31
EA008005B1 (ru) 2007-02-27
ZA200506550B (en) 2006-05-31
EA200501159A1 (ru) 2006-02-24
IL170297A (en) 2010-06-30
JP2006526004A (ja) 2006-11-16
JP4430067B2 (ja) 2010-03-10
DE602004000982T2 (de) 2007-05-10
US7683040B2 (en) 2010-03-23
CA2516400A1 (en) 2005-07-14
WO2005063236A1 (en) 2005-07-14
DK1605932T3 (da) 2006-09-18
US20070191308A1 (en) 2007-08-16
UA79196C2 (en) 2007-05-25
SI1605932T1 (sl) 2006-08-31
HRP20060240T3 (hr) 2007-05-31
IS8487A (is) 2006-05-26
EP1605932A1 (en) 2005-12-21
KR100718760B1 (ko) 2007-05-15
CN100374112C (zh) 2008-03-12

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 31/381, A61P 25/16

Ipc: A61K 31/381 (2011.01), A61P 25/16 (2011.01)

B25D Requested change of name of applicant approved

Owner name: UCB PHARMA GMBH (DE)

Free format text: NOME ALTERADO DE: SCHWARZ PHARMA AG

B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 8A E 9A ANUIDADES.

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 8A, 9A, 10A, 11A, 12A, 13A, 14A E 15A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.