BRPI0408453A - composto, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio afetivo - Google Patents

composto, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio afetivo

Info

Publication number
BRPI0408453A
BRPI0408453A BRPI0408453-5A BRPI0408453A BRPI0408453A BR PI0408453 A BRPI0408453 A BR PI0408453A BR PI0408453 A BRPI0408453 A BR PI0408453A BR PI0408453 A BRPI0408453 A BR PI0408453A
Authority
BR
Brazil
Prior art keywords
compound
treating
disorder
pharmaceutical composition
affective disorder
Prior art date
Application number
BRPI0408453-5A
Other languages
English (en)
Inventor
Ask Pueschl
Benny Bang-Andersen
Morten Jorgensen
Karsten Juhl
Thomas Ruhland
Kim Andersen
Jan Kehler
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35432910&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0408453(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of BRPI0408453A publication Critical patent/BRPI0408453A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM COMPOSTO, E, MéTODO PARA O TRATAMENTO DE UM DISTúRBIO AFETIVO". A invenção proporciona compostos representados pela fórmula na qual os substituintes são definidos no relatório descritivo. Os compostos são úteis no tratamento de um distúrbio afetivo incluindo depressão, distúrbios de ansiedade incluindo distúrbio de ansiedade generalizada e distúrbio de pânico e distúrbio obsessivo compulsivo.
BRPI0408453-5A 2003-04-04 2004-04-02 composto, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio afetivo BRPI0408453A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46026603P 2003-04-04 2003-04-04
DKPA200300518 2003-04-04
PCT/DK2004/000243 WO2004087662A1 (en) 2003-04-04 2004-04-02 4-(2-phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors

Publications (1)

Publication Number Publication Date
BRPI0408453A true BRPI0408453A (pt) 2006-04-04

Family

ID=35432910

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408453-5A BRPI0408453A (pt) 2003-04-04 2004-04-02 composto, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio afetivo

Country Status (27)

Country Link
US (1) US20070173522A1 (pt)
EP (1) EP1613594B1 (pt)
JP (1) JP2006522029A (pt)
KR (1) KR20060021825A (pt)
CN (1) CN100384822C (pt)
AR (1) AR043964A1 (pt)
AT (1) ATE390413T1 (pt)
AU (1) AU2004226319A1 (pt)
BR (1) BRPI0408453A (pt)
CA (1) CA2521172A1 (pt)
CL (1) CL2004000730A1 (pt)
CO (1) CO5700777A2 (pt)
DE (1) DE602004012724T2 (pt)
DK (1) DK1613594T3 (pt)
EA (1) EA009282B1 (pt)
ES (1) ES2301979T3 (pt)
HR (1) HRP20080243T3 (pt)
IS (1) IS8007A (pt)
MX (1) MXPA05010678A (pt)
NO (1) NO20055205L (pt)
NZ (1) NZ541944A (pt)
PL (1) PL1613594T3 (pt)
PT (1) PT1613594E (pt)
SI (1) SI1613594T1 (pt)
UA (1) UA81300C2 (pt)
WO (1) WO2004087662A1 (pt)
ZA (1) ZA200507182B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20080478T3 (hr) 2003-04-04 2009-02-28 H. Lundbeck A/S Derivati 4-(2-fenilsulfanil-fenil)-piperidina kaoinhibitori ponovne pohrane serotonina
EP2248524A3 (en) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Preventives/remedies for stress urinary incontinence and method of screening the same
EP2742936A1 (en) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
EP2789338A3 (en) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Condensed pyridine derivate and use thereof
UA98698C2 (en) * 2008-03-03 2012-06-11 Х. Луннбек А/С Phenylsulfanylphenyl-piperidines and process for the preparation thereof
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
EP2930171A1 (en) * 2014-04-07 2015-10-14 LEK Pharmaceuticals d.d. Synthesis of vortioxetine via (2,4-dimethylphenyl)(2-iodophenyl)sulfane intermediate
CN105294554B (zh) * 2015-11-18 2017-11-07 乳源瑶族自治县大众药品贸易有限公司 苯基哌嗪衍生物及其使用方法和用途
EP3733204A4 (en) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited THERAPEUTIC AGENT FOR URINARY INCONTINENCE OF STRESS AND FECAL INCONTINENCE

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
US4018830A (en) * 1969-09-22 1977-04-19 Merck & Co., Inc. Phenylthioaralkylamines
US4055665A (en) * 1974-11-25 1977-10-25 Merck & Co., Inc. Treating arrythmia with phenylthioaralkylamines
US4066654A (en) * 1975-04-16 1978-01-03 G. D. Searle & Co. 1-triarylalkyl-4-phenyl-4-piperidine carboxylic acids and derivatives
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
US4241071A (en) * 1977-01-27 1980-12-23 American Hoechst Corporation Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
DE2802306A1 (de) * 1977-01-27 1978-08-10 Hoechst Ag Azacycloalkane, azacycloalkene und ihre derivate
US4198417A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenoxyphenylpiperidines
US4198419A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenylthiophenylpiperidines
GB8912971D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
US6410736B1 (en) * 1999-11-29 2002-06-25 Pfizer Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
AP2002002481A0 (en) * 1999-10-13 2002-06-30 Pfizer Prod Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors.
EA006071B1 (ru) * 1999-12-30 2005-08-25 Х.Лундбекк А/С Замещенные производные фенилпиперазина, их получение и применение
US6436938B1 (en) * 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression
US20020107244A1 (en) * 2001-02-02 2002-08-08 Howard Harry R. Combination treatment for depression
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну

Also Published As

Publication number Publication date
WO2004087662A1 (en) 2004-10-14
DE602004012724T2 (de) 2009-04-09
HRP20080243T3 (hr) 2009-04-30
ES2301979T3 (es) 2008-07-01
ATE390413T1 (de) 2008-04-15
DE602004012724D1 (de) 2008-05-08
CN1777585A (zh) 2006-05-24
AU2004226319A1 (en) 2004-10-14
CO5700777A2 (es) 2006-11-30
PL1613594T3 (pl) 2008-09-30
AR043964A1 (es) 2005-08-17
EP1613594B1 (en) 2008-03-26
CA2521172A1 (en) 2004-10-14
UA81300C2 (en) 2007-12-25
EA200501579A1 (ru) 2006-04-28
MXPA05010678A (es) 2005-12-12
ZA200507182B (en) 2006-12-27
PT1613594E (pt) 2008-07-01
KR20060021825A (ko) 2006-03-08
CN100384822C (zh) 2008-04-30
EA009282B1 (ru) 2007-12-28
US20070173522A1 (en) 2007-07-26
CL2004000730A1 (es) 2005-02-18
IS8007A (is) 2005-08-29
DK1613594T3 (da) 2008-07-14
SI1613594T1 (sl) 2008-08-31
JP2006522029A (ja) 2006-09-28
EP1613594A1 (en) 2006-01-11
HK1090051A1 (en) 2006-12-15
NZ541944A (en) 2008-05-30
NO20055205L (no) 2005-11-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.