ATE390413T1 - 4-(2-phenylsulfanyl-phenyl)-1,2,3,6- tetrahydropyridinderivaten zur verwendung als serotonin-wiederaufnahmehemmer - Google Patents

4-(2-phenylsulfanyl-phenyl)-1,2,3,6- tetrahydropyridinderivaten zur verwendung als serotonin-wiederaufnahmehemmer

Info

Publication number
ATE390413T1
ATE390413T1 AT04725299T AT04725299T ATE390413T1 AT E390413 T1 ATE390413 T1 AT E390413T1 AT 04725299 T AT04725299 T AT 04725299T AT 04725299 T AT04725299 T AT 04725299T AT E390413 T1 ATE390413 T1 AT E390413T1
Authority
AT
Austria
Prior art keywords
reuppost
phenylsulfanyl
serotonin
inhibitors
phenyl
Prior art date
Application number
AT04725299T
Other languages
English (en)
Inventor
Ask Pueschl
Benny Bang-Andersen
Morten Jorgensen
Karsten Juhl
Thomas Ruhland
Kim Andersen
Jan Kehler
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35432910&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE390413(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE390413T1 publication Critical patent/ATE390413T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT04725299T 2003-04-04 2004-04-02 4-(2-phenylsulfanyl-phenyl)-1,2,3,6- tetrahydropyridinderivaten zur verwendung als serotonin-wiederaufnahmehemmer ATE390413T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46026603P 2003-04-04 2003-04-04
DKPA200300518 2003-04-04

Publications (1)

Publication Number Publication Date
ATE390413T1 true ATE390413T1 (de) 2008-04-15

Family

ID=35432910

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04725299T ATE390413T1 (de) 2003-04-04 2004-04-02 4-(2-phenylsulfanyl-phenyl)-1,2,3,6- tetrahydropyridinderivaten zur verwendung als serotonin-wiederaufnahmehemmer

Country Status (27)

Country Link
US (1) US20070173522A1 (de)
EP (1) EP1613594B1 (de)
JP (1) JP2006522029A (de)
KR (1) KR20060021825A (de)
CN (1) CN100384822C (de)
AR (1) AR043964A1 (de)
AT (1) ATE390413T1 (de)
AU (1) AU2004226319A1 (de)
BR (1) BRPI0408453A (de)
CA (1) CA2521172A1 (de)
CL (1) CL2004000730A1 (de)
CO (1) CO5700777A2 (de)
DE (1) DE602004012724T2 (de)
DK (1) DK1613594T3 (de)
EA (1) EA009282B1 (de)
ES (1) ES2301979T3 (de)
HR (1) HRP20080243T3 (de)
IS (1) IS8007A (de)
MX (1) MXPA05010678A (de)
NO (1) NO20055205L (de)
NZ (1) NZ541944A (de)
PL (1) PL1613594T3 (de)
PT (1) PT1613594E (de)
SI (1) SI1613594T1 (de)
UA (1) UA81300C2 (de)
WO (1) WO2004087662A1 (de)
ZA (1) ZA200507182B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004087156A1 (en) 2003-04-04 2004-10-14 H. Lundbeck A/S 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
EP2727585A1 (de) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo Screening-Methode
EP2789338A3 (de) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Kondensiertes Pyridinderivat und seine Verwendung
UA98698C2 (en) * 2008-03-03 2012-06-11 Х. Луннбек А/С Phenylsulfanylphenyl-piperidines and process for the preparation thereof
EP2510949A4 (de) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutikum für fibromyalgie
EP2930171A1 (de) * 2014-04-07 2015-10-14 LEK Pharmaceuticals d.d. Synthese von Vortioxetin über (2,4-Dimethylphenyl) (2-Iodophenyl)sulfan-Zwischenprodukt
CN105294554B (zh) * 2015-11-18 2017-11-07 乳源瑶族自治县大众药品贸易有限公司 苯基哌嗪衍生物及其使用方法和用途
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
US4018830A (en) * 1969-09-22 1977-04-19 Merck & Co., Inc. Phenylthioaralkylamines
US4055665A (en) * 1974-11-25 1977-10-25 Merck & Co., Inc. Treating arrythmia with phenylthioaralkylamines
US4066654A (en) * 1975-04-16 1978-01-03 G. D. Searle & Co. 1-triarylalkyl-4-phenyl-4-piperidine carboxylic acids and derivatives
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
DE2802306A1 (de) * 1977-01-27 1978-08-10 Hoechst Ag Azacycloalkane, azacycloalkene und ihre derivate
US4241071A (en) * 1977-01-27 1980-12-23 American Hoechst Corporation Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
US4198419A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenylthiophenylpiperidines
US4198417A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenoxyphenylpiperidines
GB8912971D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
WO2001027068A1 (en) * 1999-10-13 2001-04-19 Pfizer Products Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
US6410736B1 (en) * 1999-11-29 2002-06-25 Pfizer Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
ATE261959T1 (de) * 1999-12-30 2004-04-15 Lundbeck & Co As H Substituierte phenyl-piperazin-derivate, deren herstellung und verwendung
US6436938B1 (en) * 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression
US20020107244A1 (en) * 2001-02-02 2002-08-08 Howard Harry R. Combination treatment for depression
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну

Also Published As

Publication number Publication date
NO20055205L (no) 2005-11-04
PT1613594E (pt) 2008-07-01
WO2004087662A1 (en) 2004-10-14
MXPA05010678A (es) 2005-12-12
DE602004012724D1 (de) 2008-05-08
EA200501579A1 (ru) 2006-04-28
EP1613594B1 (de) 2008-03-26
KR20060021825A (ko) 2006-03-08
ES2301979T3 (es) 2008-07-01
BRPI0408453A (pt) 2006-04-04
UA81300C2 (en) 2007-12-25
EA009282B1 (ru) 2007-12-28
DE602004012724T2 (de) 2009-04-09
US20070173522A1 (en) 2007-07-26
IS8007A (is) 2005-08-29
CL2004000730A1 (es) 2005-02-18
CN1777585A (zh) 2006-05-24
EP1613594A1 (de) 2006-01-11
PL1613594T3 (pl) 2008-09-30
CA2521172A1 (en) 2004-10-14
HK1090051A1 (en) 2006-12-15
ZA200507182B (en) 2006-12-27
CO5700777A2 (es) 2006-11-30
AU2004226319A1 (en) 2004-10-14
CN100384822C (zh) 2008-04-30
JP2006522029A (ja) 2006-09-28
SI1613594T1 (sl) 2008-08-31
HRP20080243T3 (hr) 2009-04-30
DK1613594T3 (da) 2008-07-14
AR043964A1 (es) 2005-08-17
NZ541944A (en) 2008-05-30

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