BRPI0408601A - compostos com ação nootrópica, sua preparação, composições farmacêuticas os contendo, e seu uso - Google Patents

compostos com ação nootrópica, sua preparação, composições farmacêuticas os contendo, e seu uso

Info

Publication number
BRPI0408601A
BRPI0408601A BRPI0408601-5A BRPI0408601A BRPI0408601A BR PI0408601 A BRPI0408601 A BR PI0408601A BR PI0408601 A BRPI0408601 A BR PI0408601A BR PI0408601 A BRPI0408601 A BR PI0408601A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
action
nootropic
Prior art date
Application number
BRPI0408601-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Carlo Farina
Stefania Gagliardi
Carlo Parini
Marisa Martinelli
Carla Ghelardini
Original Assignee
Nikem Research Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikem Research Srl filed Critical Nikem Research Srl
Publication of BRPI0408601A publication Critical patent/BRPI0408601A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0408601-5A 2003-03-24 2004-03-22 compostos com ação nootrópica, sua preparação, composições farmacêuticas os contendo, e seu uso BRPI0408601A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000573A ITMI20030573A1 (it) 2003-03-24 2003-03-24 Composti ad azione nootropica, loro preparazione,
PCT/EP2004/050339 WO2004085438A2 (fr) 2003-03-24 2004-03-22 Composes presentant une action nootropique, leur preparation, compositions pharmaceutiques les contenant, et leur utilisation

Publications (1)

Publication Number Publication Date
BRPI0408601A true BRPI0408601A (pt) 2006-03-07

Family

ID=33042696

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408601-5A BRPI0408601A (pt) 2003-03-24 2004-03-22 compostos com ação nootrópica, sua preparação, composições farmacêuticas os contendo, e seu uso

Country Status (23)

Country Link
US (3) US7544705B2 (fr)
EP (1) EP1608655B8 (fr)
JP (1) JP4920408B2 (fr)
CN (1) CN100522963C (fr)
AT (1) ATE401327T1 (fr)
AU (1) AU2004224087B2 (fr)
BR (1) BRPI0408601A (fr)
CA (1) CA2520008C (fr)
CY (1) CY1108401T1 (fr)
DE (1) DE602004015089D1 (fr)
DK (1) DK1608655T3 (fr)
EA (1) EA009558B1 (fr)
ES (1) ES2309534T3 (fr)
HR (1) HRP20050833A2 (fr)
IT (1) ITMI20030573A1 (fr)
NO (1) NO20054898L (fr)
NZ (1) NZ543154A (fr)
PL (2) PL378939A1 (fr)
PT (1) PT1608655E (fr)
RS (1) RS20050725A (fr)
SI (1) SI1608655T1 (fr)
WO (1) WO2004085438A2 (fr)
ZA (1) ZA200508578B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
EP1925304A1 (fr) * 2006-11-15 2008-05-28 Nikem Research S.R.L. Pyrrolo[1,2-a]imidazoledione pour traitement d'une neuropathie périphérique induite par une chimiothérapie
AU2012201853B2 (en) * 2007-04-16 2013-06-27 Neurotune Ag Use of dimiracetam in the treatment of chronic pain
ITMI20070770A1 (it) * 2007-04-16 2008-10-17 Brane Discovery S R L Impiego di dimiracetam nel trattamento del dolore cronico
ES2865504T3 (es) 2008-10-16 2021-10-15 Univ Johns Hopkins Procedimientos y composiciones para la mejora de la función cognitiva
US9125898B2 (en) 2008-11-14 2015-09-08 Neurotune Ag Acetam derivatives for pain relief
AU2011215870B2 (en) * 2010-02-09 2016-01-28 The Johns Hopkins University Methods and compositions for improving cognitive function
PT2598504E (pt) * 2010-07-26 2014-07-14 Neurotune Ag Novo processo de fabrico de dimiracetam
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
WO2014144663A1 (fr) 2013-03-15 2014-09-18 The Johns Hopkins University Procédés et compositions pour améliorer la fonction cognitive
WO2016191288A1 (fr) 2015-05-22 2016-12-01 Agenebio, Inc. Compositions pharmaceutiques de lévétiracétam à libération prolongée
JOP20190251A1 (ar) 2017-05-31 2019-10-21 Metys Pharmaceuticals AG تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية
CN113195494B (zh) 2018-12-04 2024-06-28 美蒂斯制药公司 包含非外消旋比例的R-2-（取代的磺酰基）-六氢-吡咯并[1,2-a]吡嗪-6（2H）-酮和S-2-（取代的磺酰基）-六氢-吡咯并[1,2- a]吡嗪-6（2H）-酮的协同组合物
BR112021010739A2 (pt) 2018-12-04 2021-08-24 Metys Pharmaceuticals AG Composições sinérgicas compreendendo (r)-(2-(2-oxopirrolidina-1-il)butanamida e (s)-2-(2-oxopirrolidina-1-il)butanamida) em uma proporção não racêmica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582838A (en) * 1984-08-24 1986-04-15 Warner-Lambert Company Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators
IT1233860B (it) * 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
US5200406A (en) * 1988-02-08 1993-04-06 I.S.F. Societa Per Azioni Pharmaceutically useful 2,5-dioxo-1H-octahydroimidazo[1,2-A]azepines
JP3400466B2 (ja) * 1991-10-28 2003-04-28 日本水産株式会社 高純度エイコサペンタエン酸またはそのエステルの製造方法
GB9123641D0 (en) * 1991-11-07 1992-01-02 Isf Spa Process
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
EP1925304A1 (fr) * 2006-11-15 2008-05-28 Nikem Research S.R.L. Pyrrolo[1,2-a]imidazoledione pour traitement d'une neuropathie périphérique induite par une chimiothérapie

Also Published As

Publication number Publication date
EP1608655B8 (fr) 2008-10-15
EP1608655B1 (fr) 2008-07-16
EA200501501A1 (ru) 2006-04-28
US7544705B2 (en) 2009-06-09
DK1608655T3 (da) 2008-11-03
ITMI20030573A1 (it) 2004-09-25
PT1608655E (pt) 2008-10-07
ZA200508578B (en) 2007-04-25
EP1608655A2 (fr) 2005-12-28
NZ543154A (en) 2008-03-28
US20100173945A1 (en) 2010-07-08
CA2520008C (fr) 2011-08-23
CN100522963C (zh) 2009-08-05
SI1608655T1 (sl) 2008-12-31
CA2520008A1 (fr) 2004-10-07
CY1108401T1 (el) 2014-02-12
EA009558B1 (ru) 2008-02-28
AU2004224087A1 (en) 2004-10-07
WO2004085438A3 (fr) 2004-11-25
US7732473B2 (en) 2010-06-08
US20070027137A1 (en) 2007-02-01
AU2004224087B2 (en) 2010-04-01
ES2309534T3 (es) 2008-12-16
RS20050725A (sr) 2007-11-15
WO2004085438A2 (fr) 2004-10-07
CN1756757A (zh) 2006-04-05
JP4920408B2 (ja) 2012-04-18
DE602004015089D1 (de) 2008-08-28
JP2006523198A (ja) 2006-10-12
HK1083837A1 (en) 2006-07-14
HRP20050833A2 (en) 2006-02-28
NO20054898L (no) 2005-10-24
US20090163565A1 (en) 2009-06-25
PL1608655T3 (pl) 2009-03-31
ATE401327T1 (de) 2008-08-15
PL378939A1 (pl) 2006-06-12

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: C07D 487/04, A61K 31/4188, A61P 25/00

Ipc: C07D 487/04 (2011.01), A61K 31/4188 (2011.01)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: BRANE DISCOVERY S.R.L. IN LIQUIDAZIONE (IT)

Free format text: TRANSFERIDO DE: NIKEM RESEARCH S.R.L.

B25A Requested transfer of rights approved

Owner name: BRANE DISCOVERY S.R.L. IN LIQUIDAZIONE (IT) , NIKE

Free format text: TRANSFERIDO DE: BRANE DISCOVERY S.R.L. IN LIQUIDAZIONE

B25A Requested transfer of rights approved

Owner name: BRANE DISCOVERY S.R.L. IN LIQUIDAZIONE (IT) , NEUR

Free format text: TRANSFERIDO DE: NIKEM RESEARCH S.R.L.

B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11M Decision cancelled [chapter 11.13 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements