BRPI0409196A - bactéria produtora de l-aminoácido, e, método para produzir um l-aminoácido aromático - Google Patents
bactéria produtora de l-aminoácido, e, método para produzir um l-aminoácido aromáticoInfo
- Publication number
- BRPI0409196A BRPI0409196A BRPI0409196-5A BRPI0409196A BRPI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A
- Authority
- BR
- Brazil
- Prior art keywords
- amino acid
- producing
- aromatic
- bacteria
- producing bacteria
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"BACTéRIA PRODUTORA DE L-AMINOáCIDO, E, MéTODO PARA PRODUZIR UM L-AMINOáCIDO AROMáTICO". A presente invenção diz respeito a um método para produzir L-aminoácidos, tais como L-triptofano, L-fenilalanina e L-tirosina, com o uso de uma bactéria pertencente ao gênero Escherichia, e em que a produtividade de L-aminoácido da referida bactéria é aumentada pelo aumento de uma atividade de PEP carboxiquinase, que é codificada pelo gene pckA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003109477/13A RU2268300C2 (ru) | 2003-04-07 | 2003-04-07 | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
| RU2003109477 | 2003-04-07 | ||
| PCT/JP2004/004968 WO2004090125A2 (en) | 2003-04-07 | 2004-04-06 | Method for producing l-amino acid using bacteria having enhanced expression of the gene pcka |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0409196A true BRPI0409196A (pt) | 2006-04-11 |
| BRPI0409196B1 BRPI0409196B1 (pt) | 2015-09-22 |
Family
ID=33157466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409196-5A BRPI0409196B1 (pt) | 2003-04-07 | 2004-04-06 | Método para produzir um l-aminoácido aromático |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060035348A1 (pt) |
| EP (1) | EP1611241B1 (pt) |
| JP (1) | JP4500980B2 (pt) |
| BR (1) | BRPI0409196B1 (pt) |
| RU (1) | RU2268300C2 (pt) |
| WO (1) | WO2004090125A2 (pt) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
| US7915018B2 (en) * | 2004-10-22 | 2011-03-29 | Ajinomoto Co., Inc. | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family |
| WO2006088231A1 (en) | 2005-02-18 | 2006-08-24 | Ajinomoto Co., Inc. | A method for producing a non-aromatic l-amino acid using a bacterium of the enterobacteriaceae family having expression of the csra gene attenuated |
| WO2006088235A1 (en) | 2005-02-18 | 2006-08-24 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family |
| JP2006230329A (ja) * | 2005-02-28 | 2006-09-07 | Mitsukan Group Honsha:Kk | 酢酸発酵能が増強された酢酸菌、及び該酢酸菌を用いた食酢の製造方法 |
| DE102005018835A1 (de) | 2005-04-22 | 2006-11-02 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| DE102005019040A1 (de) | 2005-04-23 | 2006-10-26 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| DE602006015302D1 (de) * | 2005-05-16 | 2010-08-19 | Ajinomoto Kk | Verfahren zur herstellung einer l-aminosäure unter verwendung eines bakteriums der familie enterobacteriaceae mit abgeschwächter expression des kefb-gens |
| EP1899452B1 (en) * | 2005-06-17 | 2010-10-20 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the fucpikur operon |
| EP1907529A1 (en) * | 2005-07-25 | 2008-04-09 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE cpxR GENE |
| EP1929027B1 (en) * | 2005-08-09 | 2009-01-14 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE ybiV GENE |
| RU2333950C2 (ru) * | 2005-12-27 | 2008-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ АРОМАТИЧЕСКИХ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Methylophilus |
| EP1979486B1 (en) | 2006-01-30 | 2013-04-17 | Ajinomoto Co., Inc. | L-amino acid producing bacterium and method of producing l-amino acid |
| EP2004803A2 (en) | 2006-03-23 | 2008-12-24 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using bacterium of theenterobacteriaceae family with attenuated expression of a gene coding for small rna |
| EP2007873B1 (en) * | 2006-04-18 | 2015-11-18 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| JP2010017081A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
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| US8673601B2 (en) * | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸または核酸の製造方法 |
| DE102007051024A1 (de) | 2007-03-05 | 2008-09-11 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP1975241A1 (de) | 2007-03-29 | 2008-10-01 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| RU2364628C2 (ru) * | 2007-07-18 | 2009-08-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Способ получения l-аминокислот с использованием бактерии семейства enterobacteriaceae |
| DE102007044134A1 (de) | 2007-09-15 | 2009-03-19 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102007052270A1 (de) | 2007-11-02 | 2009-05-07 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| EP2060636A1 (de) | 2007-11-14 | 2009-05-20 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| CA2712779C (en) * | 2008-01-22 | 2021-03-16 | Genomatica, Inc. | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol |
| JP5217780B2 (ja) * | 2008-02-08 | 2013-06-19 | 味の素株式会社 | L−アミノ酸を生産する微生物及びl−アミノ酸の製造法 |
| RU2008105793A (ru) * | 2008-02-19 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена |
| EP2098597A1 (de) | 2008-03-04 | 2009-09-09 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DK2262901T3 (en) | 2008-03-05 | 2019-01-21 | Genomatica Inc | ORGANISMS PRODUCING PRIMARY ALCOHOL |
| ES2656790T3 (es) * | 2008-03-27 | 2018-02-28 | Genomatica, Inc. | Microorganismos para la producción de ácido adípico y otros compuestos |
| WO2009135074A2 (en) * | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| DE102008002309A1 (de) | 2008-06-09 | 2009-12-10 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102008040352A1 (de) | 2008-07-11 | 2010-01-14 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| US20100021978A1 (en) * | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
| DE102008044768A1 (de) | 2008-08-28 | 2010-03-04 | Evonik Degussa Gmbh | Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| WO2010057022A1 (en) * | 2008-11-14 | 2010-05-20 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| EP2373781A4 (en) * | 2008-12-16 | 2012-10-10 | Genomatica Inc | MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS |
| CA2756705C (en) | 2009-04-02 | 2017-04-11 | University Of Florida Research Foundation, Inc. | Engineered bacterial cells for succinate production |
| MY176050A (en) * | 2009-04-30 | 2020-07-22 | Genomatica Inc | Organisms for the production of 1,3-butanediol |
| BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
| EP2427544B1 (en) | 2009-05-07 | 2019-07-17 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid |
| JP2012526561A (ja) * | 2009-05-15 | 2012-11-01 | ゲノマチカ, インク. | シクロヘキサノンの産生のための生物 |
| EP2440669A4 (en) * | 2009-06-10 | 2013-08-28 | Genomatica Inc | MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL |
| EP3190174A1 (en) | 2009-08-05 | 2017-07-12 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
| JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| US8715971B2 (en) | 2009-09-09 | 2014-05-06 | Genomatica, Inc. | Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol |
| KR20120083908A (ko) | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-coa, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
| KR20180014240A (ko) | 2009-10-23 | 2018-02-07 | 게노마티카 인코포레이티드 | 아닐린의 제조를 위한 미생물 |
| JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| KR20120120493A (ko) * | 2009-12-10 | 2012-11-01 | 게노마티카 인코포레이티드 | 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체 |
| JP2013517796A (ja) | 2010-01-29 | 2013-05-20 | ジェノマティカ・インコーポレイテッド | p−トルイル酸およびテレフタル酸を生合成するための方法および微生物 |
| US8445244B2 (en) * | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) * | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| CA2797409C (en) | 2010-05-05 | 2019-12-24 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of butadiene |
| PH12013500158A1 (en) | 2010-07-26 | 2013-03-11 | Genomatica Inc | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| KR101327093B1 (ko) * | 2012-01-06 | 2013-11-07 | 씨제이제일제당 (주) | L-아미노산을 생산할 수 있는 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법 |
| JP5958653B2 (ja) | 2013-10-02 | 2016-08-02 | 味の素株式会社 | アンモニア制御装置およびアンモニア制御方法 |
| US10428359B2 (en) * | 2016-10-03 | 2019-10-01 | Ajinomoto Co, Inc. | Method for producing L-amino acid |
| MX2022009706A (es) * | 2020-02-07 | 2022-09-07 | Metabolic Explorer Sa | Microorganismo modificado y metodo para la produccion mejorada de ectoina. |
| CN116790568A (zh) * | 2022-03-15 | 2023-09-22 | 廊坊梅花生物技术开发有限公司 | 磷酸烯醇式丙酮酸羧激酶突变体及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2004A (en) * | 1841-03-12 | Improvement in the manner of constructing and propelling steam-vessels | ||
| US2003A (en) * | 1841-03-12 | Improvement in horizontal windivhlls | ||
| US2005A (en) * | 1841-03-16 | Improvement in the manner of constructing molds for casting butt-hinges | ||
| US2002A (en) * | 1841-03-12 | Tor and planter for plowing | ||
| DE4232468A1 (de) * | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung |
| US5985617A (en) * | 1997-02-18 | 1999-11-16 | Liao; James C. | Microorganisms and methods for overproduction of DAHP by cloned PPS gene |
| CA2199853C (en) * | 1994-09-16 | 2009-03-24 | James C. Liao | Microorganisms and methods for overproduction of dahp by cloned pps gene |
| JP4032441B2 (ja) * | 1995-08-30 | 2008-01-16 | 味の素株式会社 | L−アミノ酸の製造方法 |
| RU2144564C1 (ru) * | 1998-10-13 | 2000-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | ФРАГМЕНТ ДНК rhtB, КОДИРУЮЩИЙ СИНТЕЗ БЕЛКА RhtB, ПРИДАЮЩЕГО УСТОЙЧИВОСТЬ К L-ГОМОСЕРИНУ БАКТЕРИЯМ ESCHERICHIA COLI, И СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ |
| RU2212447C2 (ru) * | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| US6916637B2 (en) * | 2000-09-30 | 2005-07-12 | Degussa Ag | Fermentation process for the preparation of L-amino acids using strains of the family Enterobacteriaceae |
| EP1320626B1 (en) * | 2000-09-30 | 2009-11-04 | Evonik Degussa GmbH | Fermentation process for the preparation of l-amino acids using strains of the family enterobacteriaceae |
| MXPA04004874A (es) * | 2001-11-23 | 2004-09-03 | Ajinomoto Kk | Procedimiento para producir l-aminoacido utilizando escherichia. |
-
2003
- 2003-04-07 RU RU2003109477/13A patent/RU2268300C2/ru active
-
2004
- 2004-04-06 WO PCT/JP2004/004968 patent/WO2004090125A2/en not_active Ceased
- 2004-04-06 EP EP04726021.1A patent/EP1611241B1/en not_active Expired - Lifetime
- 2004-04-06 BR BRPI0409196-5A patent/BRPI0409196B1/pt not_active IP Right Cessation
- 2004-04-06 JP JP2006507708A patent/JP4500980B2/ja not_active Expired - Lifetime
-
2005
- 2005-09-27 US US11/235,254 patent/US20060035348A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0409196B1 (pt) | 2015-09-22 |
| US20060035348A1 (en) | 2006-02-16 |
| JP4500980B2 (ja) | 2010-07-14 |
| JP2006521816A (ja) | 2006-09-28 |
| WO2004090125A2 (en) | 2004-10-21 |
| EP1611241B1 (en) | 2016-11-02 |
| EP1611241A2 (en) | 2006-01-04 |
| WO2004090125A8 (en) | 2005-06-30 |
| RU2268300C2 (ru) | 2006-01-20 |
| WO2004090125A3 (en) | 2004-11-25 |
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