BRPI0409196A - bactéria produtora de l-aminoácido, e, método para produzir um l-aminoácido aromático - Google Patents
bactéria produtora de l-aminoácido, e, método para produzir um l-aminoácido aromáticoInfo
- Publication number
- BRPI0409196A BRPI0409196A BRPI0409196-5A BRPI0409196A BRPI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A BR PI0409196 A BRPI0409196 A BR PI0409196A
- Authority
- BR
- Brazil
- Prior art keywords
- amino acid
- producing
- aromatic
- bacteria
- producing bacteria
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"BACTéRIA PRODUTORA DE L-AMINOáCIDO, E, MéTODO PARA PRODUZIR UM L-AMINOáCIDO AROMáTICO". A presente invenção diz respeito a um método para produzir L-aminoácidos, tais como L-triptofano, L-fenilalanina e L-tirosina, com o uso de uma bactéria pertencente ao gênero Escherichia, e em que a produtividade de L-aminoácido da referida bactéria é aumentada pelo aumento de uma atividade de PEP carboxiquinase, que é codificada pelo gene pckA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2003109477 | 2003-04-07 | ||
| RU2003109477/13A RU2268300C2 (ru) | 2003-04-07 | 2003-04-07 | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
| PCT/JP2004/004968 WO2004090125A2 (en) | 2003-04-07 | 2004-04-06 | Method for producing l-amino acid using bacteria having enhanced expression of the gene pcka |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0409196A true BRPI0409196A (pt) | 2006-04-11 |
| BRPI0409196B1 BRPI0409196B1 (pt) | 2015-09-22 |
Family
ID=33157466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409196-5A BRPI0409196B1 (pt) | 2003-04-07 | 2004-04-06 | Método para produzir um l-aminoácido aromático |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060035348A1 (pt) |
| EP (1) | EP1611241B1 (pt) |
| JP (1) | JP4500980B2 (pt) |
| BR (1) | BRPI0409196B1 (pt) |
| RU (1) | RU2268300C2 (pt) |
| WO (1) | WO2004090125A2 (pt) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
| US7915018B2 (en) | 2004-10-22 | 2011-03-29 | Ajinomoto Co., Inc. | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family |
| ATE417119T1 (de) | 2005-02-18 | 2008-12-15 | Ajinomoto Kk | Verfahren zur herstellung einer nichtaromatischen l-aminosäure unter verwendung eines bakteriums der familie enterobacteriaceae mit abgeschwächter expression des csra-gens |
| EP1848811B1 (en) | 2005-02-18 | 2009-08-05 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family |
| JP2006230329A (ja) * | 2005-02-28 | 2006-09-07 | Mitsukan Group Honsha:Kk | 酢酸発酵能が増強された酢酸菌、及び該酢酸菌を用いた食酢の製造方法 |
| DE102005018835A1 (de) | 2005-04-22 | 2006-11-02 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| DE102005019040A1 (de) | 2005-04-23 | 2006-10-26 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| WO2006123764A1 (en) * | 2005-05-16 | 2006-11-23 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the kefb gene |
| WO2006135075A1 (en) * | 2005-06-17 | 2006-12-21 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the fucpikur operon |
| EP1907529A1 (en) * | 2005-07-25 | 2008-04-09 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE cpxR GENE |
| EP1929027B1 (en) * | 2005-08-09 | 2009-01-14 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE ybiV GENE |
| RU2333950C2 (ru) * | 2005-12-27 | 2008-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ АРОМАТИЧЕСКИХ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Methylophilus |
| EP1979486B1 (en) | 2006-01-30 | 2013-04-17 | Ajinomoto Co., Inc. | L-amino acid producing bacterium and method of producing l-amino acid |
| WO2007119574A2 (en) * | 2006-03-23 | 2007-10-25 | Ajinomoto Co., Inc. | A method for producing an l-amino acid using bacterium of the enterobacteriaceae family with attenuated expression of a gene coding for small rna |
| EP2007873B1 (en) * | 2006-04-18 | 2015-11-18 | Ajinomoto Co., Inc. | A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| JP2010017082A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010017081A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| WO2008091627A2 (en) * | 2007-01-22 | 2008-07-31 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸または核酸の製造方法 |
| DE102007051024A1 (de) | 2007-03-05 | 2008-09-11 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP1975241A1 (de) | 2007-03-29 | 2008-10-01 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| RU2364628C2 (ru) * | 2007-07-18 | 2009-08-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Способ получения l-аминокислот с использованием бактерии семейства enterobacteriaceae |
| DE102007044134A1 (de) | 2007-09-15 | 2009-03-19 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102007052270A1 (de) | 2007-11-02 | 2009-05-07 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| EP2060636A1 (de) | 2007-11-14 | 2009-05-20 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| CN107090424A (zh) | 2008-01-22 | 2017-08-25 | 基因组股份公司 | 利用合成气或其它气态碳源和甲醇的方法和有机体 |
| JP5217780B2 (ja) * | 2008-02-08 | 2013-06-19 | 味の素株式会社 | L−アミノ酸を生産する微生物及びl−アミノ酸の製造法 |
| RU2008105793A (ru) * | 2008-02-19 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена |
| EP2098597A1 (de) | 2008-03-04 | 2009-09-09 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| EP3450550A1 (en) | 2008-03-05 | 2019-03-06 | Genomatica, Inc. | Primary alcohol producing organisms |
| PL2265709T3 (pl) * | 2008-03-27 | 2018-05-30 | Genomatica, Inc. | Mikroorganizmy do produkcji kwasu adypinowego i innych związków |
| WO2009135074A2 (en) * | 2008-05-01 | 2009-11-05 | Genomatica, Inc. | Microorganisms for the production of methacrylic acid |
| DE102008002309A1 (de) | 2008-06-09 | 2009-12-10 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102008040352A1 (de) | 2008-07-11 | 2010-01-14 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| US20100021978A1 (en) * | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
| DE102008044768A1 (de) | 2008-08-28 | 2010-03-04 | Evonik Degussa Gmbh | Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| US20100184173A1 (en) * | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| CA2746952A1 (en) * | 2008-12-16 | 2010-06-24 | Genomatica, Inc. | Microorganisms and methods for conversion of syngas and other carbon sources to useful products |
| US20120058530A1 (en) | 2009-04-02 | 2012-03-08 | University Of Florida Research Foundation Inc. | Engineering the pathway for succinate production |
| BRPI1013505A2 (pt) | 2009-04-30 | 2018-02-14 | Genomatica Inc | organismos para a produção de isopropanol, n-butanol, e isobutanol |
| EP3865569B1 (en) * | 2009-04-30 | 2023-10-04 | Genomatica, Inc. | Organisms for the production of 1,3-butanediol |
| WO2010129936A1 (en) | 2009-05-07 | 2010-11-11 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid |
| KR20120036851A (ko) * | 2009-05-15 | 2012-04-18 | 게노마티카 인코포레이티드 | 사이클로헥사논의 제조를 위한 유기체 |
| WO2010144746A2 (en) * | 2009-06-10 | 2010-12-16 | Genomatica, Inc. | Microorganisms and methods for carbon-efficient biosynthesis of mek and 2-butanol |
| DK2462221T3 (en) | 2009-08-05 | 2017-05-22 | Genomatica Inc | SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID |
| JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| US8715971B2 (en) | 2009-09-09 | 2014-05-06 | Genomatica, Inc. | Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol |
| AU2010306785B2 (en) | 2009-10-13 | 2016-01-14 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto |
| US20110097767A1 (en) * | 2009-10-23 | 2011-04-28 | Priti Pharkya | Microorganisms for the production of aniline |
| JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| CN102753698A (zh) * | 2009-12-10 | 2012-10-24 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
| CN102834508A (zh) * | 2010-01-29 | 2012-12-19 | 基因组股份公司 | 用于生物合成对甲苯甲酸和对苯二甲酸的微生物和方法 |
| US8637286B2 (en) * | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) * | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| KR20190006103A (ko) | 2010-05-05 | 2019-01-16 | 게노마티카 인코포레이티드 | 부타디엔을 생합성하기 위한 미생물 및 방법 |
| WO2012018624A2 (en) | 2010-07-26 | 2012-02-09 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| KR101327093B1 (ko) * | 2012-01-06 | 2013-11-07 | 씨제이제일제당 (주) | L-아미노산을 생산할 수 있는 미생물 및 이를 이용하여 l-아미노산을 생산하는 방법 |
| CN106459857B (zh) | 2013-10-02 | 2019-04-19 | 味之素株式会社 | 氨控制装置及氨控制方法 |
| US10428359B2 (en) * | 2016-10-03 | 2019-10-01 | Ajinomoto Co, Inc. | Method for producing L-amino acid |
| BR112022015402A2 (pt) * | 2020-02-07 | 2022-10-11 | Metabolic Explorer Sa | Micro-organismo modificado e método para a produção de ectoína melhorada |
| CN116790568A (zh) * | 2022-03-15 | 2023-09-22 | 廊坊梅花生物技术开发有限公司 | 磷酸烯醇式丙酮酸羧激酶突变体及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2002A (en) * | 1841-03-12 | Tor and planter for plowing | ||
| US2004A (en) * | 1841-03-12 | Improvement in the manner of constructing and propelling steam-vessels | ||
| US2003A (en) * | 1841-03-12 | Improvement in horizontal windivhlls | ||
| US2005A (en) * | 1841-03-16 | Improvement in the manner of constructing molds for casting butt-hinges | ||
| DE4232468A1 (de) * | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung |
| EP0782621B1 (en) * | 1994-09-16 | 2006-03-08 | THE TEXAS A&M UNIVERSITY SYSTEM | Microorganisms and method for overproduction of DAHP by cloned PPS gene |
| US5985617A (en) * | 1997-02-18 | 1999-11-16 | Liao; James C. | Microorganisms and methods for overproduction of DAHP by cloned PPS gene |
| JP4032441B2 (ja) * | 1995-08-30 | 2008-01-16 | 味の素株式会社 | L−アミノ酸の製造方法 |
| RU2144564C1 (ru) * | 1998-10-13 | 2000-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | ФРАГМЕНТ ДНК rhtB, КОДИРУЮЩИЙ СИНТЕЗ БЕЛКА RhtB, ПРИДАЮЩЕГО УСТОЙЧИВОСТЬ К L-ГОМОСЕРИНУ БАКТЕРИЯМ ESCHERICHIA COLI, И СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ |
| RU2212447C2 (ru) * | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| WO2002029080A2 (en) * | 2000-09-30 | 2002-04-11 | Degussa Ag | Fermentation process for the preparation of l-amino acids using strains of the family enterobacteriaceae |
| US6916637B2 (en) * | 2000-09-30 | 2005-07-12 | Degussa Ag | Fermentation process for the preparation of L-amino acids using strains of the family Enterobacteriaceae |
| EP1449918B1 (en) * | 2001-11-23 | 2010-06-09 | Ajinomoto Co., Inc. | Process for producing l-amino acid using escherichia |
-
2003
- 2003-04-07 RU RU2003109477/13A patent/RU2268300C2/ru active
-
2004
- 2004-04-06 JP JP2006507708A patent/JP4500980B2/ja not_active Expired - Lifetime
- 2004-04-06 BR BRPI0409196-5A patent/BRPI0409196B1/pt not_active IP Right Cessation
- 2004-04-06 WO PCT/JP2004/004968 patent/WO2004090125A2/en not_active Ceased
- 2004-04-06 EP EP04726021.1A patent/EP1611241B1/en not_active Expired - Lifetime
-
2005
- 2005-09-27 US US11/235,254 patent/US20060035348A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1611241A2 (en) | 2006-01-04 |
| US20060035348A1 (en) | 2006-02-16 |
| WO2004090125A3 (en) | 2004-11-25 |
| RU2268300C2 (ru) | 2006-01-20 |
| JP4500980B2 (ja) | 2010-07-14 |
| WO2004090125A8 (en) | 2005-06-30 |
| JP2006521816A (ja) | 2006-09-28 |
| BRPI0409196B1 (pt) | 2015-09-22 |
| WO2004090125A2 (en) | 2004-10-21 |
| EP1611241B1 (en) | 2016-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2004090125A8 (en) | Method for producing l-amino acid using bacteria having enhanced expression of the gene pcka | |
| BR0004832A (pt) | Bacéteria pertencendo ao gênero escherichia, e, processo para produzir l-aminoácido | |
| BR0114101A (pt) | cepas de escherichia coli que superproduzem l-treonina e processos para a produção de l-treonina por fermentação | |
| BR0200350A (pt) | Bactéria produtora de l-aminoácido pertencente ao gênero escherichia, e, método produzir l-aminoácido | |
| ATE518951T1 (de) | Mikroorganismus des genus corynebacterium mit verstärkter l-lysin-produktivität und verfahren zur herstellung von l-lysin damit | |
| BRPI0715584B8 (pt) | método para produzir um l-aminoácido | |
| MY141980A (en) | L- amino acid-producing bacterium and a method for producing l-amino acid | |
| ATE461270T1 (de) | Verfahren zur herstellung von l-aminosäuren | |
| BR112013018385A2 (pt) | microorganismo com produtividade de l-aminoácidos aumentada e processo de produção de l-aminoácidos usando o mesmo | |
| ATE460496T1 (de) | Verfahren zur herstellung von l-aminosäure | |
| BR0016656A (pt) | Bactéria corineforme, método para produzir um l-aminoácido, e, dna | |
| BR112021021294A2 (pt) | Organismo microbiano e microrganismo de ocorrência não natural, métodos para produzir adipato-semialdeído, ácido 6-aminocapróico, hexametileno diamina, caprolactama, e, ácido 6-aminocapróico, hexametilenodiamina, 1,6-hexanodiol, caprolactona ou caprolactama bioderivado | |
| WO2005103228A3 (en) | L-amino acid-producing bacterium and a method for producing l-amino acid | |
| SE0502254L (sv) | Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission | |
| ATE438731T1 (de) | Verfahren zur herstellung einer l-aminosäure unter verwendung eines bakteriums der familie enterobacteriaceae | |
| DE602006019763D1 (de) | Mikroorganismus und verfahren zur herstellung von l-methionin | |
| BRPI0507978A (pt) | bactéria produtora de l-aminoácido pertencente à famìlia enterobacteriaceae, e, método para produzir um l-aminoácido | |
| CY1111730T1 (el) | Διαδικασια για την παρασκευη γκαμπαπεντινης | |
| BRPI0517008A8 (pt) | Método para produzir l-treonina | |
| BR0308255A (pt) | Alelos do gene acea de bactérias corineforme | |
| BRPI0408219A (pt) | seqüências de nucleotìdeos de bactérias corineformes codificando proteìnas envolvidas no metabolismo da l-serina bem como microorganismo e processo para a preparação microbiana de l-serina | |
| BR0202782A (pt) | Método de produção de ácido pirrolidona carboxìlico ou de um sal do mesmo | |
| BR0002493A (pt) | Processo para a preparação de l-aminoácidos por fermentação e sequências de nucleotìdeos que codificam o gene accda | |
| BRPI0417230A (pt) | bactéria produtora da l-treonina pertencente ao gênero escherichia, e, método para produzir l-treonina | |
| DE50107566D1 (de) | Nukleotidsequenzen kodierend fur proteine beteiligt an der biosynthese von l-serin, verbessertes verfahren zur mikrobiellen herstellung von l-serin sowie ein dazu geeigneter genetisch veranderter mikroorganismus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/09/2015, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 22/09/2025 |