BRPI0409801A - método para produzir ácido l-glutámico por fermentação - Google Patents
método para produzir ácido l-glutámico por fermentaçãoInfo
- Publication number
- BRPI0409801A BRPI0409801A BRPI0409801-3A BRPI0409801A BRPI0409801A BR PI0409801 A BRPI0409801 A BR PI0409801A BR PI0409801 A BRPI0409801 A BR PI0409801A BR PI0409801 A BRPI0409801 A BR PI0409801A
- Authority
- BR
- Brazil
- Prior art keywords
- glutamic acid
- producing
- medium
- fermentation
- accumulate
- Prior art date
Links
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 title abstract 20
- 229960002989 glutamic acid Drugs 0.000 title abstract 10
- 238000000855 fermentation Methods 0.000 title abstract 3
- 230000004151 fermentation Effects 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 235000019766 L-Lysine Nutrition 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 230000002269 spontaneous effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODO PARA PRODUZIR ACIDO L-GLUTáMICO POR FERMENTAçãO". Em um processo para produzir ácido L-glutâmico via fermentação que compreende cultivar, em um meio líquido em um valor de pH específico contendo ácido L-glutâmico na concentração de saturação e uma fonte de carbono, um microorganismo capaz de metabolizar a fonte de carbono e acumular ácido L-glutâmico no meio líquido descrito acima no valor de pH descrito acima em uma quantidade excedendo a concentração de saturação de ácido L-glutâmico sob tais condições que o meio tem sido ajustado para um nível de pH permitindo a precipitação de ácido L-glutâmico para deste modo formar e acumular ácido L-glutâmico no estado de precipitado do meio, L-Lisina é adicionada no meio e assim <244>-cristais de ácido L-glutârmico são precipitados no caso no qual a concentração de ácido L-glutâmico no meio é menor do que o nível permitindo a cristalização espontânea.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003128722 | 2003-05-07 | ||
| PCT/JP2004/006031 WO2004099426A1 (ja) | 2003-05-07 | 2004-05-07 | L-グルタミン酸の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0409801A true BRPI0409801A (pt) | 2006-05-09 |
Family
ID=33432051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409801-3A BRPI0409801A (pt) | 2003-05-07 | 2004-05-07 | método para produzir ácido l-glutámico por fermentação |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7294491B2 (pt) |
| EP (1) | EP1624069A4 (pt) |
| JP (1) | JP5325372B2 (pt) |
| KR (1) | KR20060015582A (pt) |
| CN (1) | CN100383252C (pt) |
| AU (1) | AU2004236516A1 (pt) |
| BR (1) | BRPI0409801A (pt) |
| RU (1) | RU2005138030A (pt) |
| WO (1) | WO2004099426A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| JP4599726B2 (ja) * | 2001-02-20 | 2010-12-15 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| TWI361834B (en) * | 2005-04-12 | 2012-04-11 | Kyowa Hakko Bio Co Ltd | A method for producing amino acids |
| JP2010017082A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| BRPI0806790B1 (pt) | 2007-01-22 | 2017-02-14 | Ajinomoto Kk | microorganismo, e, método para produzir um l-aminoácido |
| EP2343371B1 (en) | 2008-09-05 | 2015-10-21 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
| ES2624913T3 (es) | 2008-09-08 | 2017-07-18 | Ajinomoto Co., Inc. | Microorganismo que produce un L-aminoácido y procedimiento para producir un L-aminoácido |
| EP4239070A4 (en) | 2020-10-28 | 2025-09-10 | Ajinomoto Kk | PROCESS FOR THE PRODUCTION OF L-AMINO ACID |
| CN115088829B (zh) * | 2022-06-06 | 2024-03-01 | 呼伦贝尔东北阜丰生物科技有限公司 | 提高味精产品色度的生产工艺 |
| US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
| WO2025141837A1 (ja) | 2023-12-28 | 2025-07-03 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
| WO2025141838A1 (ja) | 2023-12-28 | 2025-07-03 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL236891A (pt) * | 1958-03-07 | |||
| US3220929A (en) * | 1964-02-10 | 1965-11-30 | Kyowa Hakko Kogyo Kk | Microbiological production of amino acid by reductive amination |
| JPS61139398A (ja) | 1984-12-12 | 1986-06-26 | Kyowa Hakko Kogyo Co Ltd | Ｌ−グルタミン酸の製造法 |
| JPS61268185A (ja) | 1984-12-27 | 1986-11-27 | Asahi Chem Ind Co Ltd | グルタミン酸デヒドロゲナ−ゼ産生遺伝子を含むｄｎａ断片 |
| JPS62288A (ja) | 1985-03-09 | 1987-01-06 | Sanraku Inc | 発酵法によるｌ−アミノ酸の製造方法 |
| JP2520895B2 (ja) | 1987-03-04 | 1996-07-31 | 旭化成工業株式会社 | Ｌ―グルタミン酸の製造方法 |
| JP3880636B2 (ja) | 1994-01-10 | 2007-02-14 | 味の素株式会社 | 発酵法によるｌ−グルタミン酸の製造法 |
| DE19681532T1 (de) | 1995-08-23 | 1998-12-03 | Ajinomoto Kk | Verfahren zur Herstellung von L-Glutaminsäure durch Fermentation |
| JPH09285294A (ja) * | 1996-04-23 | 1997-11-04 | Ajinomoto Co Inc | 発酵法によるｌ−グルタミン酸の製造法 |
| JPH1059911A (ja) * | 1996-08-16 | 1998-03-03 | Ajinomoto Co Inc | 酸性アミノ酸の晶析方法 |
| AU746542B2 (en) * | 1998-03-18 | 2002-05-02 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| AU756507B2 (en) | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| PE20001128A1 (es) | 1998-10-19 | 2000-11-14 | Ajinomoto Kk | Bacteria productora del acido l-glutamico y procedimiento para obtener el acido l-glutamico |
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| JP4560998B2 (ja) * | 2001-02-05 | 2010-10-13 | 味の素株式会社 | 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌 |
| JP4599726B2 (ja) * | 2001-02-20 | 2010-12-15 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| JP2002238592A (ja) * | 2001-02-20 | 2002-08-27 | Ajinomoto Co Inc | Ｌ−グルタミン酸の製造法 |
| JP4599725B2 (ja) | 2001-02-20 | 2010-12-15 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| JP4614180B2 (ja) * | 2001-07-30 | 2011-01-19 | 味の素株式会社 | グルタミン酸の転移再結晶による精製方法 |
| JP3932945B2 (ja) | 2002-03-27 | 2007-06-20 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
-
2004
- 2004-05-07 EP EP04731716A patent/EP1624069A4/en not_active Withdrawn
- 2004-05-07 BR BRPI0409801-3A patent/BRPI0409801A/pt not_active Application Discontinuation
- 2004-05-07 CN CNB2004800122465A patent/CN100383252C/zh not_active Expired - Fee Related
- 2004-05-07 RU RU2005138030/13A patent/RU2005138030A/ru not_active Application Discontinuation
- 2004-05-07 WO PCT/JP2004/006031 patent/WO2004099426A1/ja not_active Ceased
- 2004-05-07 KR KR1020057021045A patent/KR20060015582A/ko not_active Withdrawn
- 2004-05-07 AU AU2004236516A patent/AU2004236516A1/en not_active Abandoned
- 2004-05-07 JP JP2005505988A patent/JP5325372B2/ja not_active Expired - Fee Related
-
2005
- 2005-11-03 US US11/265,288 patent/US7294491B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004236516A1 (en) | 2004-11-18 |
| CN1833029A (zh) | 2006-09-13 |
| US7294491B2 (en) | 2007-11-13 |
| WO2004099426A1 (ja) | 2004-11-18 |
| EP1624069A4 (en) | 2011-06-29 |
| WO2004099426A8 (ja) | 2006-01-19 |
| KR20060015582A (ko) | 2006-02-17 |
| RU2005138030A (ru) | 2006-04-20 |
| US20060084151A1 (en) | 2006-04-20 |
| JP5325372B2 (ja) | 2013-10-23 |
| JPWO2004099426A1 (ja) | 2006-07-13 |
| CN100383252C (zh) | 2008-04-23 |
| EP1624069A1 (en) | 2006-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O ART. 8O COMBINADO COM ART. 13 DA LPI. |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |